TargetScan_136 megaCluster: 1 Residual: 0.10

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_136 1 0.10 6 0 0.608187 0.995

Members

Displaying 1 - 34 of 34
14102 Fas (TNF receptor superfamily member 6)

Details for - - Fas (TNF receptor superfamily member 6)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14102

Tuberculist Genomic Region

14766 G protein-coupled receptor 56

Details for - - G protein-coupled receptor 56

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14766

Tuberculist Genomic Region

15903 inhibitor of DNA binding 3

Details for RP23-118A9.1 - inhibitor of DNA binding 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15903

Tuberculist Genomic Region

18033 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105

Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18033

Tuberculist Genomic Region

18590 platelet derived growth factor, alpha

Details for - - platelet derived growth factor, alpha

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18590

Tuberculist Genomic Region

20448 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

Details for RP23-17P12.1 - ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20448

Tuberculist Genomic Region

21949 tumor necrosis factor (ligand) superfamily, member 8

Details for - - tumor necrosis factor (ligand) superfamily, member 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 21949

Tuberculist Genomic Region

353346 G protein-coupled receptor 141

Details for - - G protein-coupled receptor 141

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 353346

Tuberculist Genomic Region

69573 hypoxia inducible lipid droplet associated

Details for - - hypoxia inducible lipid droplet associated

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69573

Tuberculist Genomic Region

71720 oxysterol binding protein-like 3

Details for - - oxysterol binding protein-like 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71720

Tuberculist Genomic Region

72536 T cell activation Rho GTPase activating protein

Details for - - T cell activation Rho GTPase activating protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72536

Tuberculist Genomic Region

100504169 predicted gene, 20098

Details for - - predicted gene, 20098

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100504169

Tuberculist Genomic Region

104709 phosphoinositide-3-kinase, regulatory subunit 6

Details for RP23-432M23.3 - phosphoinositide-3-kinase, regulatory subunit 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 104709

Tuberculist Genomic Region

108078 oxidized low density lipoprotein (lectin-like) receptor 1

Details for - - oxidized low density lipoprotein (lectin-like) receptor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 108078

Tuberculist Genomic Region

12504 CD4 antigen

Details for - - CD4 antigen

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12504

Tuberculist Genomic Region

14696 guanine nucleotide binding protein (G protein), beta 4

Details for - - guanine nucleotide binding protein (G protein), beta 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14696

Tuberculist Genomic Region

15901 inhibitor of DNA binding 1

Details for RP23-106A3.1 - inhibitor of DNA binding 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15901

Tuberculist Genomic Region

16362 interferon regulatory factor 1

Details for RP23-303F24.1 - interferon regulatory factor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16362

Tuberculist Genomic Region

170716 cytochrome P450, family 4, subfamily f, polypeptide 13

Details for - - cytochrome P450, family 4, subfamily f, polypeptide 13

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 170716

Tuberculist Genomic Region

17261 myocyte enhancer factor 2D

Details for - - myocyte enhancer factor 2D

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17261

Tuberculist Genomic Region

17873 growth arrest and DNA-damage-inducible 45 beta

Details for - - growth arrest and DNA-damage-inducible 45 beta

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17873

Tuberculist Genomic Region

18414 oncostatin M receptor

Details for - - oncostatin M receptor

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18414

Tuberculist Genomic Region

20299 chemokine (C-C motif) ligand 22

Details for - - chemokine (C-C motif) ligand 22

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20299

Tuberculist Genomic Region

22164 tumor necrosis factor (ligand) superfamily, member 4

Details for - - tumor necrosis factor (ligand) superfamily, member 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22164

Tuberculist Genomic Region

286940 filamin, beta

Details for - - filamin, beta

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 286940

Tuberculist Genomic Region

320129 adrenergic receptor kinase, beta 2

Details for - - adrenergic receptor kinase, beta 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 320129

Tuberculist Genomic Region

628746 predicted gene 6910

Details for - - predicted gene 6910

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 628746

Tuberculist Genomic Region

66610 ABI gene family, member 3

Details for RP23-151M22.4 - ABI gene family, member 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66610

Tuberculist Genomic Region

69660 transmembrane BAX inhibitor motif containing 1

Details for - - transmembrane BAX inhibitor motif containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69660

Tuberculist Genomic Region

70435 inverted formin, FH2 and WH2 domain containing

Details for - - inverted formin, FH2 and WH2 domain containing

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70435

Tuberculist Genomic Region

70640 DCP2 decapping enzyme homolog (S. cerevisiae)

Details for - - DCP2 decapping enzyme homolog (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70640

Tuberculist Genomic Region

71973 RNA binding protein with multiple splicing 2

Details for - - RNA binding protein with multiple splicing 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71973

Tuberculist Genomic Region

74257 tetraspanin 17

Details for - - tetraspanin 17

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74257

Tuberculist Genomic Region

99633 latrophilin 2

Details for - - latrophilin 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 99633

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
Hoxa6.1 0.15625 0.000000731

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.00000000014 NAAAGAAAMAAA NA 4.2 CCCCRCCCCCW SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$ZFP281_01_M01597, V$SP1_03_M02281, V$SP1_Q2_01_M00933, V$SP4_Q5_M01273, V$SP1_Q4_01_M00932, V$SP1_Q6_M00196, V$SP1_02_M01303, V$KLF7_03_M02773, V$SP4_03_M02810, V$GKLF_02_M01588, V$GC_01_M00255, V$CACD_01_M01113, V$SP1_Q6_01_M00931, V$UF1H3BETA_Q6_M01068, V$ZFP281_04_M02831, V$EKLF_Q5_M01874, V$KROX_Q6_M00982, V$SP1SP3_Q4_M01219, V$EGR1_Q6_M01873, V$ZBP89_Q4_M01816, V$MAZ_Q6_01_M02023, V$CKROX_Q2_M01175, V$EGR1_06_M02744, V$MAZ_Q6_M00649, V$MAZR_01_M00491, V$CACBINDINGPROTEIN_Q6_M00720, V$ZFP740_03_M02834, V$ZNF219_01_M01122, V$SP1_01_M00008, V$WT1_Q6_01_M02036, V$BCL6B_04_M02844, V$WT1_Q6_M01118, V$KLF15_Q2_M01714, V$CACCCBINDINGFACTOR_Q6_M00721, V$EGR_Q6_M00807, V$FKLF_Q5_M01837, V$ASCL2_04_M02841, V$GLI3_Q5_01_M01657, V$ZFP410_04_M02936, V$MOVOB_01_M01104, V$INSM1_01_M02268, V$E2F3_Q6_M02089, V$SOX14_04_M02901, V$SMAD4_04_M02898, V$EGR2_Q6_M02092, V$NGFIC_01_M00244, Sp4.1, Klf7.1, Zfp281.2, Egr1.1, Zfp740.1, Bcl6b.2, Ascl2.2, Zfp410.1, Sox13.2, Smad3.1, Zif268.1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, ZNF740_C2H2_full_monomeric_10_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, KLF13_C2H2_full_monomeric_18_1, Zfp740_C2H2_DBD_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
0.77 CGGAGC NA 1.05 CGAGCAGC

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.72 CGTCGA NA NA 0.82 GGTCGACG NA NA

3p UTR PITA

miRNAs percTargets pValue
mmu-miR-331-3p 0.607143 0.0000675

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-150 0.433333 0.0000138

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