TargetScan_166 megaCluster: 11 Residual: 0.16 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_166	11	0.16	15	0	0.956694	0

Members

Displaying 1 - 35 of 35

13722 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 Details for - - aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13722 Tuberculist Genomic Region	19184 protease (prosome, macropain) 26S subunit, ATPase 5 Details for RP23-418O11.3 - protease (prosome, macropain) 26S subunit, ATPase 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19184 Tuberculist Genomic Region
52683 non-SMC condensin II complex, subunit H2 Details for - - non-SMC condensin II complex, subunit H2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52683 Tuberculist Genomic Region	66752 RIKEN cDNA 4933404O12 gene Details for - - RIKEN cDNA 4933404O12 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66752 Tuberculist Genomic Region
66975 trafficking protein particle complex 13 Details for - - trafficking protein particle complex 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66975 Tuberculist Genomic Region	67881 magnesium-dependent phosphatase 1 Details for - - magnesium-dependent phosphatase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67881 Tuberculist Genomic Region
109785 phosphoglucomutase 3 Details for - - phosphoglucomutase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109785 Tuberculist Genomic Region	11739 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 Details for - - solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11739 Tuberculist Genomic Region
11792 apurinic/apyrimidinic endonuclease 1 Details for - - apurinic/apyrimidinic endonuclease 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11792 Tuberculist Genomic Region	11891 RAB27A, member RAS oncogene family Details for - - RAB27A, member RAS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11891 Tuberculist Genomic Region
17846 COMM domain containing 1 Details for RP23-242C19.3 - COMM domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17846 Tuberculist Genomic Region	18203 N-terminal Asn amidase Details for - - N-terminal Asn amidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18203 Tuberculist Genomic Region
27398 mitochondrial ribosomal protein L2 Details for RP23-76I16.2 - mitochondrial ribosomal protein L2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27398 Tuberculist Genomic Region	30932 zinc finger protein 330 Details for - - zinc finger protein 330 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30932 Tuberculist Genomic Region
381038 presenilin associated, rhomboid-like Details for - - presenilin associated, rhomboid-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381038 Tuberculist Genomic Region	381678 zinc finger, CW type with PWWP domain 1 Details for - - zinc finger, CW type with PWWP domain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381678 Tuberculist Genomic Region
52653 NudC domain containing 2 Details for RP23-382C18.4 - NudC domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52653 Tuberculist Genomic Region	53331 syntaxin 7 Details for - - syntaxin 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53331 Tuberculist Genomic Region
56451 succinate-CoA ligase, GDP-forming, alpha subunit Details for - - succinate-CoA ligase, GDP-forming, alpha subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56451 Tuberculist Genomic Region	56532 receptor-interacting serine-threonine kinase 3 Details for - - receptor-interacting serine-threonine kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56532 Tuberculist Genomic Region
66191 immediate early response 3 interacting protein 1 Details for - - immediate early response 3 interacting protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66191 Tuberculist Genomic Region	66411 tubulin folding cofactor B Details for - - tubulin folding cofactor B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66411 Tuberculist Genomic Region
67201 glyoxalase domain containing 4 Details for RP23-147P4.6 - glyoxalase domain containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67201 Tuberculist Genomic Region	68080 GPN-loop GTPase 3 Details for - - GPN-loop GTPase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68080 Tuberculist Genomic Region
68114 melanoma associated antigen (mutated) 1 Details for - - melanoma associated antigen (mutated) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68114 Tuberculist Genomic Region	68202 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 Details for - - NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68202 Tuberculist Genomic Region
69574 carboxymethylenebutenolidase-like (Pseudomonas) Details for - - carboxymethylenebutenolidase-like (Pseudomonas) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69574 Tuberculist Genomic Region	69957 CDC16 cell division cycle 16 Details for - - CDC16 cell division cycle 16 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69957 Tuberculist Genomic Region
71881 adipocyte plasma membrane associated protein Details for RP23-156P22.2 - adipocyte plasma membrane associated protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71881 Tuberculist Genomic Region	71968 WD repeat domain 73 Details for - - WD repeat domain 73 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71968 Tuberculist Genomic Region
72354 tetratricopeptide repeat domain 4 Details for RP23-97O7.5 - tetratricopeptide repeat domain 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72354 Tuberculist Genomic Region	72562 pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 Details for - - pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72562 Tuberculist Genomic Region
80280 CDK5 regulatory subunit associated protein 3 Details for RP23-353J21.7 - CDK5 regulatory subunit associated protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80280 Tuberculist Genomic Region	18634 peroxisomal biogenesis factor 7 Details for - - peroxisomal biogenesis factor 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18634 Tuberculist Genomic Region
26411 mitogen-activated protein kinase kinase kinase kinase 1 Details for - - mitogen-activated protein kinase kinase kinase kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26411 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
NA

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000000081	YTTNTNTTYTT	NA	32	ARGCCCCGCCCC	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$GC_01_M00255, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$KLF7_03_M02773, V$SP2_01_M01783, V$SP1_02_M01303, V$UF1H3BETA_Q6_M01068, V$GKLF_02_M01588, V$SP1_03_M02281, V$SP1_01_M00008, V$ZFP281_01_M01597, V$CKROX_Q2_M01175, V$SP4_03_M02810, V$MAZR_01_M00491, V$MAZ_Q6_M00649, V$KROX_Q6_M00982, V$BCL6B_04_M02844, V$EGR1_06_M02744, V$SMAD4_04_M02898, V$EGR1_Q6_M01873, V$E2F3_Q6_M02089, V$ZFP281_04_M02831, V$ETF_Q6_M00695, V$CACD_01_M01113, V$SP4_04_M02914, V$ZBP89_Q4_M01816, V$ZFP410_04_M02936, Klf7.1, Sp4.1, Egr1.1, Bcl6b.2, Zfp281.2, Smad3.1, Sp4.2, Zif268.1, Zfp410.1, Zfp740.1, Ascl2.2, Glis2.1, Egr1.2, Sox13.2, Klf7.2, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, SP1_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, Klf12_C2H2_DBD_monomeric_15_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.25	CGCCCA	Egr1_MA0162.1, Klf7.2, Zif268.1, Egr1.1, Klf7.1, EGR2_C2H2_DBD_monomeric_11_1, Egr3_C2H2_DBD_monomeric_15_1, EGR2_C2H2_full_monomeric_15_1, EGR1_C2H2_full_monomeric_14_1, EGR4_C2H2_DBD_monomeric_16_2, SP8_C2H2_DBD_monomeric_12_1	1.39	CTGCGCGN	V$ZFP161_04_M02933, Zfp161.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.61	ACGCGG	NA	NA	0.62	GGGGNNAT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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