TargetScan_169 megaCluster: 10 Residual: 0.25

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_169	10	0.25	9	0	0.695028	0.664

Members

Displaying 1 - 39 of 39

TFBS DB TF

TFs	percTargets	pValue
KLF16_C2H2_DBD_monomeric_11_1	0.974359	0.0000107

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000029	AAAAAWGMAAAA	NA	6700	GCCCCGCCNCNC	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273, V$GC_01_M00255, V$SP1_Q2_01_M00933, V$SMAD4_04_M02898, V$ETF_Q6_M00695, V$SP1_02_M01303, V$GKLF_02_M01588, V$CKROX_Q2_M01175, V$KLF7_03_M02773, V$SP1_03_M02281, V$MAZ_Q6_01_M02023, V$MAZR_01_M00491, V$MAZ_Q6_M00649, V$BCL6B_04_M02844, V$SP1_01_M00008, V$ZFP410_04_M02936, V$SP2_01_M01783, V$ZFP281_01_M01597, V$E2F3_Q6_M02089, V$ZFP281_04_M02831, V$UF1H3BETA_Q6_M01068, V$KLF15_Q2_M01714, V$SP4_03_M02810, V$PAX9_B_M00329, V$SP4_04_M02914, V$ZFP740_03_M02834, V$KROX_Q6_M00982, V$ZBP89_Q4_M01816, V$FKLF_Q5_M01837, V$SP1SP3_Q4_M01219, V$ASCL2_04_M02841, Smad3.1, Klf7.1, Bcl6b.2, Zfp410.1, Zfp281.2, Sp4.1, Sp4.2, Zfp740.1, Ascl2.2, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, KLF14_C2H2_DBD_monomeric_14_1, KLF13_C2H2_full_monomeric_18_1, SP4_C2H2_full_monomeric_17_1, ZNF740_C2H2_full_monomeric_10_1, Zfp740_C2H2_DBD_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, GLIS2_C2H2_DBD_monomeric_14_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.21	CGCAGG	NA	1.29	CCGCNCGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.48	CGGATA	NA	NA	0.54	ACCAACTT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

11927 ATX1 (antioxidant protein 1) homolog 1 (yeast) Details for RP23-336J1.1 - ATX1 (antioxidant protein 1) homolog 1 (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11927 Tuberculist Genomic Region	12747 CDC-like kinase 1 Details for - - CDC-like kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12747 Tuberculist Genomic Region
16337 insulin receptor Details for - - insulin receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16337 Tuberculist Genomic Region	16553 kinesin family member 13A Details for - - kinesin family member 13A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16553 Tuberculist Genomic Region
18749 protein kinase, cAMP dependent, catalytic, beta Details for - - protein kinase, cAMP dependent, catalytic, beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18749 Tuberculist Genomic Region	19360 RAD50 homolog (S. cerevisiae) Details for RP23-239O19.3 - RAD50 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19360 Tuberculist Genomic Region
210544 TBC1 domain family, member 31 Details for - - TBC1 domain family, member 31 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 210544 Tuberculist Genomic Region	210710 growth factor receptor bound protein 2-associated protein 3 Details for RP23-184H6.3 - growth factor receptor bound protein 2-associated protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 210710 Tuberculist Genomic Region
218639 ADP-ribosylation factor-like 15 Details for - - ADP-ribosylation factor-like 15 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 218639 Tuberculist Genomic Region	229499 Fc receptor-like 1 Details for - - Fc receptor-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229499 Tuberculist Genomic Region
233406 protein regulator of cytokinesis 1 Details for - - protein regulator of cytokinesis 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233406 Tuberculist Genomic Region	380686 cannabinoid receptor interacting protein 1 Details for RP23-348N2.3 - cannabinoid receptor interacting protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 380686 Tuberculist Genomic Region
56473 fatty acid desaturase 2 Details for - - fatty acid desaturase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56473 Tuberculist Genomic Region	72749 tonsoku-like, DNA repair protein Details for - - tonsoku-like, DNA repair protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72749 Tuberculist Genomic Region
74131 SAM and SH3 domain containing 3 Details for RP23-351G20.2 - SAM and SH3 domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74131 Tuberculist Genomic Region	75619 FAST kinase domains 2 Details for - - FAST kinase domains 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75619 Tuberculist Genomic Region
76464 cancer susceptibility candidate 5 Details for RP23-15I21.2 - cancer susceptibility candidate 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76464 Tuberculist Genomic Region	77011 TOPBP1-interacting checkpoint and replication regulator Details for - - TOPBP1-interacting checkpoint and replication regulator GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77011 Tuberculist Genomic Region
108062 cleavage stimulation factor, 3' pre-RNA subunit 2 Details for RP23-182N4.2 - cleavage stimulation factor, 3' pre-RNA subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108062 Tuberculist Genomic Region	108156 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Details for - - methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108156 Tuberculist Genomic Region
12419 chromobox 5 Details for - - chromobox 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12419 Tuberculist Genomic Region	16211 karyopherin (importin) beta 1 Details for RP23-81D2.3 - karyopherin (importin) beta 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16211 Tuberculist Genomic Region
17434 molybdenum cofactor synthesis 2 Details for - - molybdenum cofactor synthesis 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17434 Tuberculist Genomic Region	18242 ornithine aminotransferase Details for - - ornithine aminotransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18242 Tuberculist Genomic Region
18441 purinergic receptor P2Y, G-protein coupled 1 Details for - - purinergic receptor P2Y, G-protein coupled 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18441 Tuberculist Genomic Region	20024 SUB1 homolog (S. cerevisiae) Details for - - SUB1 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20024 Tuberculist Genomic Region
212285 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 Details for - - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 212285 Tuberculist Genomic Region	22129 tetratricopeptide repeat domain 3 Details for - - tetratricopeptide repeat domain 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22129 Tuberculist Genomic Region
231327 phosphoribosyl pyrophosphate amidotransferase Details for - - phosphoribosyl pyrophosphate amidotransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231327 Tuberculist Genomic Region	239743 kelch-like 6 Details for - - kelch-like 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 239743 Tuberculist Genomic Region
242474 transmembrane protein 245 Details for RP23-455B1.3 - transmembrane protein 245 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 242474 Tuberculist Genomic Region	29807 thiamine pyrophosphokinase Details for - - thiamine pyrophosphokinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 29807 Tuberculist Genomic Region
328801 zinc finger protein 414 Details for - - zinc finger protein 414 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 328801 Tuberculist Genomic Region	384009 GLI pathogenesis-related 2 Details for RP23-209M8.2 - GLI pathogenesis-related 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 384009 Tuberculist Genomic Region
68659 family with sequence similarity 198, member B Details for - - family with sequence similarity 198, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68659 Tuberculist Genomic Region	69634 citrate lyase beta like Details for - - citrate lyase beta like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69634 Tuberculist Genomic Region
69900 major facilitator superfamily domain containing 11 Details for RP23-468A19.8 - major facilitator superfamily domain containing 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69900 Tuberculist Genomic Region	74108 poly(A)-specific ribonuclease (deadenylation nuclease) Details for - - poly(A)-specific ribonuclease (deadenylation nuclease) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74108 Tuberculist Genomic Region
74205 acyl-CoA synthetase long-chain family member 3 Details for - - acyl-CoA synthetase long-chain family member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74205 Tuberculist Genomic Region

TargetScan_169 megaCluster: 10 Residual: 0.25

Summary

Members

Details for RP23-336J1.1 - ATX1 (antioxidant protein 1) homolog 1 (yeast)

Details for - - CDC-like kinase 1

Details for - - insulin receptor

Details for - - kinesin family member 13A

Details for - - protein kinase, cAMP dependent, catalytic, beta

Details for RP23-239O19.3 - RAD50 homolog (S. cerevisiae)

Details for - - TBC1 domain family, member 31

Details for RP23-184H6.3 - growth factor receptor bound protein 2-associated protein 3

Details for - - ADP-ribosylation factor-like 15

Details for - - Fc receptor-like 1

Details for - - protein regulator of cytokinesis 1

Details for RP23-348N2.3 - cannabinoid receptor interacting protein 1

Details for - - fatty acid desaturase 2

Details for - - tonsoku-like, DNA repair protein

Details for RP23-351G20.2 - SAM and SH3 domain containing 3

Details for - - FAST kinase domains 2

Details for RP23-15I21.2 - cancer susceptibility candidate 5

Details for - - TOPBP1-interacting checkpoint and replication regulator

Details for RP23-182N4.2 - cleavage stimulation factor, 3' pre-RNA subunit 2

Details for - - methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase

Details for - - chromobox 5

Details for RP23-81D2.3 - karyopherin (importin) beta 1

Details for - - molybdenum cofactor synthesis 2

Details for - - ornithine aminotransferase

Details for - - purinergic receptor P2Y, G-protein coupled 1

Details for - - SUB1 homolog (S. cerevisiae)

Details for - - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

Details for - - tetratricopeptide repeat domain 3

Details for - - phosphoribosyl pyrophosphate amidotransferase

Details for - - kelch-like 6

Details for RP23-455B1.3 - transmembrane protein 245

Details for - - thiamine pyrophosphokinase

Details for - - zinc finger protein 414

Details for RP23-209M8.2 - GLI pathogenesis-related 2

Details for - - family with sequence similarity 198, member B

Details for - - citrate lyase beta like

Details for RP23-468A19.8 - major facilitator superfamily domain containing 11

Details for - - poly(A)-specific ribonuclease (deadenylation nuclease)

Details for - - acyl-CoA synthetase long-chain family member 3

GO Terms

3p UTR PITA