TargetScan_19 megaCluster: 10 Residual: 0.23 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_19	10	0.23	13	0	0.830777	0

Members

Displaying 1 - 34 of 34

104348 zinc finger protein 120 Details for RP23-11F9.2 - zinc finger protein 120 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104348 Tuberculist Genomic Region	105377 ankyrin repeat domain 32 Details for - - ankyrin repeat domain 32 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 105377 Tuberculist Genomic Region
106795 transcription factor 19 Details for - - transcription factor 19 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106795 Tuberculist Genomic Region	106821 O-acyl-ADP-ribose deacylase 1 Details for - - O-acyl-ADP-ribose deacylase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106821 Tuberculist Genomic Region
107476 acetyl-Coenzyme A carboxylase alpha Details for RP23-123O10.1 - acetyl-Coenzyme A carboxylase alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107476 Tuberculist Genomic Region	12144 Bloom syndrome, RecQ helicase-like Details for - - Bloom syndrome, RecQ helicase-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12144 Tuberculist Genomic Region
12802 cannabinoid receptor 2 (macrophage) Details for RP23-161N17.5 - cannabinoid receptor 2 (macrophage) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12802 Tuberculist Genomic Region	14056 enhancer of zeste homolog 2 (Drosophila) Details for - - enhancer of zeste homolog 2 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14056 Tuberculist Genomic Region
15201 helicase, lymphoid specific Details for - - helicase, lymphoid specific GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15201 Tuberculist Genomic Region	16162 interleukin 12 receptor, beta 2 Details for - - interleukin 12 receptor, beta 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16162 Tuberculist Genomic Region
17216 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) Details for - - minichromosome maintenance deficient 2 mitotin (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17216 Tuberculist Genomic Region	17864 myeloblastosis oncogene-like 1 Details for - - myeloblastosis oncogene-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17864 Tuberculist Genomic Region
207474 potassium channel tetramerisation domain containing 12b Details for RP23-106P7.1 - potassium channel tetramerisation domain containing 12b GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 207474 Tuberculist Genomic Region	217304 CD300 antigen like family member B Details for - - CD300 antigen like family member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217304 Tuberculist Genomic Region
227102 ORM1-like 1 (S. cerevisiae) Details for - - ORM1-like 1 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227102 Tuberculist Genomic Region	239570 tetratricopeptide repeat domain 38 Details for - - tetratricopeptide repeat domain 38 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 239570 Tuberculist Genomic Region
269582 claspin Details for RP23-204N19.4 - claspin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269582 Tuberculist Genomic Region	52592 breast cancer metastasis-suppressor 1-like Details for - - breast cancer metastasis-suppressor 1-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52592 Tuberculist Genomic Region
56196 tyrosyl-DNA phosphodiesterase 2 Details for RP23-92G13.1 - tyrosyl-DNA phosphodiesterase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56196 Tuberculist Genomic Region	57257 vav 3 oncogene Details for DN-315E9.1 - vav 3 oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57257 Tuberculist Genomic Region
57373 A kinase (PRKA) interacting protein 1 Details for - - A kinase (PRKA) interacting protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57373 Tuberculist Genomic Region	66273 adipogenesis associated Mth938 domain containing Details for - - adipogenesis associated Mth938 domain containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66273 Tuberculist Genomic Region
67219 mediator complex subunit 18 Details for RP23-63D8.2 - mediator complex subunit 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67219 Tuberculist Genomic Region	69069 RIKEN cDNA 1810011H11 gene Details for - - RIKEN cDNA 1810011H11 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69069 Tuberculist Genomic Region
70472 ATPase family, AAA domain containing 2 Details for - - ATPase family, AAA domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70472 Tuberculist Genomic Region	71435 Rho GTPase activating protein 21 Details for RP23-436G18.3 - Rho GTPase activating protein 21 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71435 Tuberculist Genomic Region
72572 spermatogenesis associated, serine-rich 2 Details for - - spermatogenesis associated, serine-rich 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72572 Tuberculist Genomic Region	75216 centrosomal protein 128 Details for - - centrosomal protein 128 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75216 Tuberculist Genomic Region
76454 F-box protein 31 Details for MNCb-2609 - F-box protein 31 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76454 Tuberculist Genomic Region	79464 lipoic acid synthetase Details for - - lipoic acid synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 79464 Tuberculist Genomic Region
99138 START domain containing 7 Details for RP23-206D14.5 - START domain containing 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99138 Tuberculist Genomic Region	17850 methylmalonyl-Coenzyme A mutase Details for - - methylmalonyl-Coenzyme A mutase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17850 Tuberculist Genomic Region
20384 serine/arginine-rich splicing factor 5 Details for - - serine/arginine-rich splicing factor 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20384 Tuberculist Genomic Region	12566 cyclin-dependent kinase 2 Details for - - cyclin-dependent kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12566 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_E2F_Q6_01_M00920	0.323529	0.00000512

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000089	TTTGTTTTTTT	Foxd3_MA0041.1, FOXI1_MA0042.1	14000	GCYCCGCCCCYT	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$GC_01_M00255, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$KLF7_03_M02773, V$SP4_Q5_M01273, V$SP4_03_M02810, V$GKLF_02_M01588, V$SP1_02_M01303, V$ZFP281_01_M01597, V$SP1_03_M02281, V$SP1_01_M00008, V$UF1H3BETA_Q6_M01068, V$SP1SP3_Q4_M01219, V$BCL6B_04_M02844, V$SP2_01_M01783, V$MAZR_01_M00491, V$ETF_Q6_M00695, V$KLF15_Q2_M01714, V$MAZ_Q6_01_M02023, V$CACD_01_M01113, V$EGR1_Q6_M01873, V$ZFP410_04_M02936, V$ZBP89_Q4_M01816, V$KROX_Q6_M00982, V$EGR1_06_M02744, V$SMAD4_04_M02898, Klf7.1, Sp4.1, Bcl6b.2, Zfp410.1, Egr1.1, Smad3.1, Zfp740.1, Zfp281.2, SP1_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, KLF14_C2H2_DBD_monomeric_14_1, KLF13_C2H2_full_monomeric_18_1, Klf12_C2H2_DBD_monomeric_15_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.4	TTCGCG	V$E2F_01_M00024, V$E2F_Q6_M00427, V$E2F1_Q6_01_M00940, V$E2F1_Q6_M00431, V$E2F_Q4_M00426, V$E2F_Q3_M00425, V$E2F4DP1_01_M00738, V$E2F_03_M00516, V$E2F_Q4_02_M00939, V$E2F_Q3_01_M00918, V$E2F_02_M00050, V$E2F4DP2_01_M00739, V$E2F1DP1RB_01_M00740, V$E2F1DP1_01_M00736, V$E2F_Q4_01_M00919	1.53	TTTCGCGC	V$E2F1_Q6_01_M00940, V$E2F1_Q6_M00431, V$E2F1_Q3_01_M00938, V$E2F_Q6_M00427, V$E2F4_Q6_M02090, V$E2F1DP1_01_M00736, V$E2F_Q3_M00425, V$E2F4DP2_01_M00739, V$E2F_Q4_M00426, V$E2F_03_M00516, V$E2F4DP1_01_M00738, V$E2F1DP1RB_01_M00740, V$E2F1DP2_01_M00737, V$E2F_Q3_01_M00918, V$E2F_02_M00050, V$E2F_01_M00024, V$E2F_Q4_02_M00939, V$E2F_Q6_01_M00920, V$E2F_Q4_01_M00919, V$ZF5_01_M00716

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.38	TATTGC	NA	NA	0.5	TTGTCNNC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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