TargetScan_190 megaCluster: 1 Residual: 0.26 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_190	1	0.26	15	0	0.874479	0

Members

Displaying 1 - 35 of 35

11847 EGL nine homolog 3 (C. elegans) Details for - - EGL nine homolog 3 (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 112407 Tuberculist Genomic Region	13653 arginase type II Details for - - arginase type II GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11847 Tuberculist Genomic Region
14629 early growth response 1 Details for - - early growth response 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13653 Tuberculist Genomic Region	14674 glutamate-cysteine ligase, catalytic subunit Details for - - glutamate-cysteine ligase, catalytic subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14629 Tuberculist Genomic Region
16172 guanine nucleotide binding protein, alpha 13 Details for RP23-465A12.1 - guanine nucleotide binding protein, alpha 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14674 Tuberculist Genomic Region	16177 interleukin 17 receptor A Details for - - interleukin 17 receptor A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16172 Tuberculist Genomic Region
17135 interleukin 1 receptor, type I Details for - - interleukin 1 receptor, type I GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16177 Tuberculist Genomic Region	19696 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) Details for - - v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17135 Tuberculist Genomic Region
20238 reticuloendotheliosis oncogene Details for - - reticuloendotheliosis oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19696 Tuberculist Genomic Region	20266 ataxin 1 Details for - - ataxin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20238 Tuberculist Genomic Region
20893 sodium channel, voltage-gated, type I, beta Details for - - sodium channel, voltage-gated, type I, beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20266 Tuberculist Genomic Region	214150 basic helix-loop-helix family, member e40 Details for - - basic helix-loop-helix family, member e40 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20893 Tuberculist Genomic Region
21812 argonaute RISC catalytic subunit 3 Details for RP23-113P22.6 - argonaute RISC catalytic subunit 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 214150 Tuberculist Genomic Region	22339 transforming growth factor, beta receptor I Details for RP23-457P12.1 - transforming growth factor, beta receptor I GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21812 Tuberculist Genomic Region
230752 vascular endothelial growth factor A Details for - - vascular endothelial growth factor A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22339 Tuberculist Genomic Region	231130 eva-1 homolog B (C. elegans) Details for RP23-365D10.2 - eva-1 homolog B (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230752 Tuberculist Genomic Region
235380 TNFAIP3 interacting protein 2 Details for - - TNFAIP3 interacting protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231130 Tuberculist Genomic Region	236285 Dmx-like 2 Details for RP24-383M20.1 - Dmx-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 235380 Tuberculist Genomic Region
242509 LanC lantibiotic synthetase component C-like 3 (bacterial) Details for RP23-423L11.1 - LanC lantibiotic synthetase component C-like 3 (bacterial) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236285 Tuberculist Genomic Region	26397 basonuclin 2 Details for RP23-229A22.1 - basonuclin 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 242509 Tuberculist Genomic Region
338367 mitogen-activated protein kinase kinase 3 Details for RP23-467E19.1 - mitogen-activated protein kinase kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26397 Tuberculist Genomic Region	380921 myosin ID Details for - - myosin ID GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 338367 Tuberculist Genomic Region
387609 diacylglycerol kinase, eta Details for mCG_120030 - diacylglycerol kinase, eta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 380921 Tuberculist Genomic Region	53376 zinc fingers and homeoboxes 2 Details for - - zinc fingers and homeoboxes 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 387609 Tuberculist Genomic Region
54604 ubiquitin specific peptidase 2 Details for MNCb-0190 - ubiquitin specific peptidase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53376 Tuberculist Genomic Region	67533 pecanex homolog (Drosophila) Details for - - pecanex homolog (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54604 Tuberculist Genomic Region
68074 PTPRF interacting protein, binding protein 1 (liprin beta 1) Details for - - PTPRF interacting protein, binding protein 1 (liprin beta 1) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67533 Tuberculist Genomic Region	71602 RIKEN cDNA A930013F10 gene Details for - - RIKEN cDNA A930013F10 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68074 Tuberculist Genomic Region
72504 myosin IE Details for - - myosin IE GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71602 Tuberculist Genomic Region	75869 TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor Details for - - TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72504 Tuberculist Genomic Region
80859 ADP-ribosylation factor-like 5B Details for - - ADP-ribosylation factor-like 5B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75869 Tuberculist Genomic Region	16402 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80859 Tuberculist Genomic Region
240396 integrin alpha 5 (fibronectin receptor alpha) Details for - - integrin alpha 5 (fibronectin receptor alpha) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16402 Tuberculist Genomic Region	57783 mex3 homolog C (C. elegans) Details for - - mex3 homolog C (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240396 Tuberculist Genomic Region
Details for - - TNFAIP3 interacting protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57783 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_SP1_Q6_01_M00931, SP1_MA0079.2, V_SP1_03_M02281, KLF16_C2H2_DBD_monomeric_11_1, V_GC_01_M00255, V_SP1_Q6_M00196, Ascl2.2, V_ASCL2_04_M02841, V_SP1_Q2_01_M00933, V_SP1_Q4_01_M00932	1, 1, 1, 1, 1, 1, 1, 1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000000012	TTTYTTTTTCTT	NA	0.00000000068	CYSCCYCCNCCC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_02_M01303, V$ZNF219_01_M01122, V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$ZFP281_04_M02831, V$SP1_Q2_01_M00933, V$SP1_Q4_01_M00932, V$SP1_Q6_M00196, V$ZFP281_01_M01597, V$SP1SP3_Q4_M01219, V$WT1_Q6_M01118, V$GC_01_M00255, V$SP1_03_M02281, V$MAZ_Q6_01_M02023, V$FKLF_Q5_M01837, V$UF1H3BETA_Q6_M01068, V$KLF7_03_M02773, V$ZFP740_03_M02834, V$CACD_01_M01113, V$MAZR_01_M00491, V$ZBP89_Q4_M01816, V$KROX_Q6_M00982, V$GKLF_02_M01588, V$CKROX_Q2_M01175, V$MAZ_Q6_M00649, V$BCL6B_04_M02844, V$ZFP410_04_M02936, Zfp281.2, Klf7.1, Zfp740.1, Bcl6b.2, Zfp410.1, Egr1.1, Ascl2.2, Sp4.1, Smad3.1, Zif268.1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.41	CGAGCG	NA	1.57	CCGNCCCG	Zfp410.1, Bcl6b.2, Smad3.1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.6	GCAACT	NA	NA	0.7	CNGACACG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-182	0.464286	0.0000151

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