TargetScan_198 megaCluster: 2 Residual: 0.15

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_198	2	0.15	9	0	0.656142	0.946

Members

Displaying 1 - 42 of 42

TFBS DB TF

TFs	percTargets	pValue
ZNF740_C2H2_full_monomeric_10_1	0.85	0.000000846

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
7.6e-23	AAARNAANAAAA	NA	53	CCCNCCCCNCCC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_02_M01303, V$ZNF219_01_M01122, V$SP1_Q6_01_M00931, V$ZFP281_04_M02831, V$SP1_03_M02281, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$CKROX_Q2_M01175, V$MAZ_Q6_01_M02023, V$SP1SP3_Q4_M01219, V$UF1H3BETA_Q6_M01068, V$ZFP281_01_M01597, V$SP1_Q4_01_M00932, V$MAZ_Q6_M00649, V$SP1_Q6_M00196, V$CACD_01_M01113, V$ZBP89_Q4_M01816, V$WT1_Q6_M01118, V$GC_01_M00255, V$EGR1_Q6_M01873, V$KLF7_03_M02773, V$KROX_Q6_M00982, V$FKLF_Q5_M01837, V$ZFP740_03_M02834, V$MAZR_01_M00491, V$GKLF_02_M01588, V$SP2_01_M01783, V$SP1_01_M00008, V$WT1_Q6_01_M02036, V$KLF15_Q2_M01714, V$RREB1_01_M00257, V$ASCL2_04_M02841, Zfp281.2, Klf7.1, Zfp740.1, Ascl2.2, Zfp410.1, Egr1.2, Bcl6b.2, Sox13.2, Egr1.1, Smad3.1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.06	GCGACT	NA	1.12	TGGCGCGA	V$E2F_Q2_M00803, V$E2F1_Q3_01_M00938, V$E2F_Q4_01_M00919, V$E2F_Q6_01_M00920, V$E2F_03_M00516, V$SMAD4_04_M02898, V$E2F_Q4_02_M00939, V$E2F_Q3_01_M00918, V$E2F3_Q6_M02089, Smad3.1, E2F2.2, E2F3.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.58	TCGACG	NA	NA	0.68	CCKGTCGT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

14825 chemokine (C-X-C motif) ligand 1 Details for - - chemokine (C-X-C motif) ligand 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14825 Tuberculist Genomic Region	212127 proline and serine rich 1 Details for - - proline and serine rich 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 212127 Tuberculist Genomic Region
241694 Ral GTPase activating protein, alpha subunit 2 (catalytic) Details for RP23-185F7.2 - Ral GTPase activating protein, alpha subunit 2 (catalytic) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241694 Tuberculist Genomic Region	67956 SET domain containing (lysine methyltransferase) 8 Details for - - SET domain containing (lysine methyltransferase) 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67956 Tuberculist Genomic Region
74761 matrix-remodelling associated 8 Details for RP23-242K15.14-001 - matrix-remodelling associated 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74761 Tuberculist Genomic Region	100503890 PET100 homolog (S. cerevisiae) Details for - - PET100 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503890 Tuberculist Genomic Region
104836 Casitas B-lineage lymphoma-like 1 Details for - - Casitas B-lineage lymphoma-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104836 Tuberculist Genomic Region	107569 5'-nucleotidase, cytosolic III Details for - - 5'-nucleotidase, cytosolic III GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107569 Tuberculist Genomic Region
12524 CD86 antigen Details for - - CD86 antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12524 Tuberculist Genomic Region	14528 GTP cyclohydrolase 1 Details for - - GTP cyclohydrolase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14528 Tuberculist Genomic Region
14977 solute carrier family 39 (zinc transporter), member 7 Details for - - solute carrier family 39 (zinc transporter), member 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14977 Tuberculist Genomic Region	15903 inhibitor of DNA binding 3 Details for RP23-118A9.1 - inhibitor of DNA binding 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15903 Tuberculist Genomic Region
16468 jumonji, AT rich interactive domain 2 Details for - - jumonji, AT rich interactive domain 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16468 Tuberculist Genomic Region	17087 lymphocyte antigen 96 Details for - - lymphocyte antigen 96 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17087 Tuberculist Genomic Region
18591 platelet derived growth factor, B polypeptide Details for - - platelet derived growth factor, B polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18591 Tuberculist Genomic Region	18712 proviral integration site 1 Details for - - proviral integration site 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18712 Tuberculist Genomic Region
19731 ral guanine nucleotide dissociation stimulator,-like 1 Details for - - ral guanine nucleotide dissociation stimulator,-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19731 Tuberculist Genomic Region	20728 Spi-C transcription factor (Spi-1/PU.1 related) Details for - - Spi-C transcription factor (Spi-1/PU.1 related) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20728 Tuberculist Genomic Region
21810 transforming growth factor, beta induced Details for - - transforming growth factor, beta induced GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21810 Tuberculist Genomic Region	244864 layilin Details for - - layilin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 244864 Tuberculist Genomic Region
268490 LSM12 homolog (S. cerevisiae) Details for RP23-167N11.2 - LSM12 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 268490 Tuberculist Genomic Region	29815 breast cancer anti-estrogen resistance 3 Details for - - breast cancer anti-estrogen resistance 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 29815 Tuberculist Genomic Region
29817 insulin-like growth factor binding protein 7 Details for - - insulin-like growth factor binding protein 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 29817 Tuberculist Genomic Region	330122 chemokine (C-X-C motif) ligand 3 Details for - - chemokine (C-X-C motif) ligand 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 330122 Tuberculist Genomic Region
387230 microRNA 99b Details for - - microRNA 99b GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 387230 Tuberculist Genomic Region	434219 tripartite motif-containing 30C Details for - - tripartite motif-containing 30C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 434219 Tuberculist Genomic Region
434484 Sp140 nuclear body protein Details for - - Sp140 nuclear body protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 434484 Tuberculist Genomic Region	67092 glycine amidinotransferase (L-arginine:glycine amidinotransferase) Details for RP23-101F14.1 - glycine amidinotransferase (L-arginine:glycine amidinotransferase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67092 Tuberculist Genomic Region
68544 RIKEN cDNA 2310036O22 gene Details for - - RIKEN cDNA 2310036O22 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68544 Tuberculist Genomic Region	74211 RIKEN cDNA 1700017B05 gene Details for - - RIKEN cDNA 1700017B05 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74211 Tuberculist Genomic Region
74442 sphingomyelin synthase 2 Details for - - sphingomyelin synthase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74442 Tuberculist Genomic Region	78655 eukaryotic translation initiation factor 3, subunit J1 Details for - - eukaryotic translation initiation factor 3, subunit J1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78655 Tuberculist Genomic Region
239122 SET domain, bifurcated 2 Details for mCG_13852 - SET domain, bifurcated 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 239122 Tuberculist Genomic Region	27226 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) Details for - - phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27226 Tuberculist Genomic Region
547253 poly (ADP-ribose) polymerase family, member 14 Details for - - poly (ADP-ribose) polymerase family, member 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 547253 Tuberculist Genomic Region	14042 exostoses (multiple) 1 Details for - - exostoses (multiple) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14042 Tuberculist Genomic Region
20821 tripartite motif-containing 21 Details for - - tripartite motif-containing 21 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20821 Tuberculist Genomic Region	21939 CD40 antigen Details for RP23-428M13.1 - CD40 antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21939 Tuberculist Genomic Region
229898 guanylate binding protein 5 Details for - - guanylate binding protein 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229898 Tuberculist Genomic Region	245944 vacuolar protein sorting 54 (yeast) Details for RP23-154K13.1 - vacuolar protein sorting 54 (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245944 Tuberculist Genomic Region
18035 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18035 Tuberculist Genomic Region	628705 PHD finger protein 11C Details for mCG_1037415 - PHD finger protein 11C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 628705 Tuberculist Genomic Region

TargetScan_198 megaCluster: 2 Residual: 0.15

Summary

Members

Details for - - chemokine (C-X-C motif) ligand 1

Details for - - proline and serine rich 1

Details for RP23-185F7.2 - Ral GTPase activating protein, alpha subunit 2 (catalytic)

Details for - - SET domain containing (lysine methyltransferase) 8

Details for RP23-242K15.14-001 - matrix-remodelling associated 8

Details for - - PET100 homolog (S. cerevisiae)

Details for - - Casitas B-lineage lymphoma-like 1

Details for - - 5'-nucleotidase, cytosolic III

Details for - - CD86 antigen

Details for - - GTP cyclohydrolase 1

Details for - - solute carrier family 39 (zinc transporter), member 7

Details for RP23-118A9.1 - inhibitor of DNA binding 3

Details for - - jumonji, AT rich interactive domain 2

Details for - - lymphocyte antigen 96

Details for - - platelet derived growth factor, B polypeptide

Details for - - proviral integration site 1

Details for - - ral guanine nucleotide dissociation stimulator,-like 1

Details for - - Spi-C transcription factor (Spi-1/PU.1 related)

Details for - - transforming growth factor, beta induced

Details for - - layilin

Details for RP23-167N11.2 - LSM12 homolog (S. cerevisiae)

Details for - - breast cancer anti-estrogen resistance 3

Details for - - insulin-like growth factor binding protein 7

Details for - - chemokine (C-X-C motif) ligand 3

Details for - - microRNA 99b

Details for - - tripartite motif-containing 30C

Details for - - Sp140 nuclear body protein

Details for RP23-101F14.1 - glycine amidinotransferase (L-arginine:glycine amidinotransferase)

Details for - - RIKEN cDNA 2310036O22 gene

Details for - - RIKEN cDNA 1700017B05 gene

Details for - - sphingomyelin synthase 2

Details for - - eukaryotic translation initiation factor 3, subunit J1

Details for mCG_13852 - SET domain, bifurcated 2

Details for - - phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Details for - - poly (ADP-ribose) polymerase family, member 14

Details for - - exostoses (multiple) 1

Details for - - tripartite motif-containing 21

Details for RP23-428M13.1 - CD40 antigen

Details for - - guanylate binding protein 5

Details for RP23-154K13.1 - vacuolar protein sorting 54 (yeast)

Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

Details for mCG_1037415 - PHD finger protein 11C

GO Terms

3p UTR PITA