TargetScan_204 megaCluster: 8 Residual: 0.14 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_204	8	0.14	15	0	0.967697	0

Members

Displaying 1 - 23 of 23

11555 adrenergic receptor, beta 2 Details for - - adrenergic receptor, beta 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11555 Tuberculist Genomic Region	320271 suppressor of cancer cell invasion Details for RP23-322M5.1 - suppressor of cancer cell invasion GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320271 Tuberculist Genomic Region
67460 2,4-dienoyl CoA reductase 1, mitochondrial Details for RP23-338J24.3 - 2,4-dienoyl CoA reductase 1, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67460 Tuberculist Genomic Region	68183 breast carcinoma amplified sequence 2 Details for - - breast carcinoma amplified sequence 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68183 Tuberculist Genomic Region
11545 poly (ADP-ribose) polymerase family, member 1 Details for - - poly (ADP-ribose) polymerase family, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11545 Tuberculist Genomic Region	14957 histone cluster 1, H1d Details for mCG_50184 - histone cluster 1, H1d GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14957 Tuberculist Genomic Region
234865 nucleoporin 133 Details for - - nucleoporin 133 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234865 Tuberculist Genomic Region	23938 mitogen-activated protein kinase kinase 5 Details for - - mitogen-activated protein kinase kinase 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23938 Tuberculist Genomic Region
26462 thioredoxin reductase 2 Details for - - thioredoxin reductase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26462 Tuberculist Genomic Region	26904 SH2 domain protein 1B1 Details for - - SH2 domain protein 1B1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26904 Tuberculist Genomic Region
270198 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Details for - - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 270198 Tuberculist Genomic Region	29858 phosphomannomutase 1 Details for - - phosphomannomutase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 29858 Tuberculist Genomic Region
30841 lysine (K)-specific demethylase 2B Details for - - lysine (K)-specific demethylase 2B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30841 Tuberculist Genomic Region	30951 chromobox 8 Details for RP23-458A23.1 - chromobox 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30951 Tuberculist Genomic Region
65099 interleukin-1 receptor-associated kinase 1 binding protein 1 Details for - - interleukin-1 receptor-associated kinase 1 binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 65099 Tuberculist Genomic Region	66841 electron transferring flavoprotein, dehydrogenase Details for - - electron transferring flavoprotein, dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66841 Tuberculist Genomic Region
70209 transmembrane protein 143 Details for - - transmembrane protein 143 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70209 Tuberculist Genomic Region	71375 forkhead box N3 Details for - - forkhead box N3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71375 Tuberculist Genomic Region
72519 transmembrane protein 55A Details for RP23-379L17.2 - transmembrane protein 55A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72519 Tuberculist Genomic Region	73668 tetratricopeptide repeat domain 21B Details for RP23-353H5.2 - tetratricopeptide repeat domain 21B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73668 Tuberculist Genomic Region
74552 NIPA-like domain containing 3 Details for RP23-332E2.5 - NIPA-like domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74552 Tuberculist Genomic Region	74610 ATP-binding cassette, sub-family B (MDR/TAP), member 8 Details for - - ATP-binding cassette, sub-family B (MDR/TAP), member 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74610 Tuberculist Genomic Region
272396 threonyl-tRNA synthetase-like 2 Details for - - threonyl-tRNA synthetase-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 272396 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
NA

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00025	GCCNCGCCCCTC	Klf4_MA0039.2, V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$GKLF_02_M01588, V$SP1_Q2_01_M00933, V$KLF7_03_M02773, V$SP1_02_M01303, V$GC_01_M00255, V$MAZ_Q6_M00649, V$CKROX_Q2_M01175, V$ZFP281_04_M02831, V$SP1_01_M00008, V$SP2_01_M01783, V$KLF15_Q2_M01714, V$BCL6B_04_M02844, V$SP4_03_M02810, V$UF1H3BETA_Q6_M01068, V$ZFP410_04_M02936, V$ZNF219_01_M01122, V$ZFP281_01_M01597, V$SMAD4_04_M02898, V$CACD_01_M01113, V$SP1_03_M02281, V$MAZ_Q6_01_M02023, V$SP1SP3_Q4_M01219, V$ZFP740_03_M02834, V$MAZR_01_M00491, V$ETF_Q6_M00695, Klf7.1, Zfp281.2, Bcl6b.2, Sp4.1, Zfp410.1, Smad3.1, Zfp740.1, Sp4.2, Egr1.1, Gcm1.2, KLF16_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, SP1_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP8_C2H2_DBD_monomeric_12_1, SP4_C2H2_full_monomeric_17_1, SP3_C2H2_DBD_monomeric_11_1, Klf12_C2H2_DBD_monomeric_15_1, ZNF740_C2H2_full_monomeric_10_1	9	AKTTTTTCMAGA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.16	GCGCCT	NA	1.56	ACCGCGAG

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.66	AGGTCG	NA	NA	0.83	AGGTCGNG	mmu-mir-6406	8mer

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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