TargetScan_212 megaCluster: 8 Residual: 0.27

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_212 8 0.27 15 0 0.867907 0

Members

Displaying 1 - 45 of 45
14712 glyceronephosphate O-acyltransferase

Details for - - glyceronephosphate O-acyltransferase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14712

Tuberculist Genomic Region

100561 solute carrier family 15, member 4

Details for - - solute carrier family 15, member 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100561

Tuberculist Genomic Region

109299 RIKEN cDNA C330006A16 gene

Details for - - RIKEN cDNA C330006A16 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 109299

Tuberculist Genomic Region

114714 RAD51 homolog C

Details for RP23-209O5.3 - RAD51 homolog C

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 114714

Tuberculist Genomic Region

13864 nuclear receptor subfamily 2, group F, member 6

Details for - - nuclear receptor subfamily 2, group F, member 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13864

Tuberculist Genomic Region

140742 sestrin 1

Details for - - sestrin 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 140742

Tuberculist Genomic Region

15115 histidyl-tRNA synthetase

Details for - - histidyl-tRNA synthetase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15115

Tuberculist Genomic Region

16987 lanosterol synthase

Details for - - lanosterol synthase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16987

Tuberculist Genomic Region

17916 myosin IF

Details for - - myosin IF

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17916

Tuberculist Genomic Region

17966 neighbor of Brca1 gene 1

Details for RP23-382C19.1 - neighbor of Brca1 gene 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17966

Tuberculist Genomic Region

18640 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Details for - - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18640

Tuberculist Genomic Region

19765 ralA binding protein 1

Details for - - ralA binding protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19765

Tuberculist Genomic Region

20598 sphingomyelin phosphodiesterase 2, neutral

Details for - - sphingomyelin phosphodiesterase 2, neutral

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20598

Tuberculist Genomic Region

209011 sirtuin 7

Details for RP23-84C12.8 - sirtuin 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 209011

Tuberculist Genomic Region

212114 NHL repeat containing 3

Details for - - NHL repeat containing 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 212114

Tuberculist Genomic Region

216829 membrane magnesium transporter 2

Details for - - membrane magnesium transporter 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 216829

Tuberculist Genomic Region

233204 TBC1 domain family, member 17

Details for - - TBC1 domain family, member 17

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 233204

Tuberculist Genomic Region

245638 TBC1 domain family, member 8B

Details for - - TBC1 domain family, member 8B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 245638

Tuberculist Genomic Region

26401 mitogen-activated protein kinase kinase kinase 1

Details for - - mitogen-activated protein kinase kinase kinase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 26401

Tuberculist Genomic Region

269254 senataxin

Details for RP23-426D2.7 - senataxin

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 269254

Tuberculist Genomic Region

27878 transcriptional adaptor 1

Details for - - transcriptional adaptor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 27878

Tuberculist Genomic Region

387175 microRNA 15b

Details for - - microRNA 15b

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 387175

Tuberculist Genomic Region

52830 proline-rich nuclear receptor coactivator 2

Details for RP23-161N17.3 - proline-rich nuclear receptor coactivator 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 52830

Tuberculist Genomic Region

56452 origin recognition complex, subunit 6

Details for - - origin recognition complex, subunit 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56452

Tuberculist Genomic Region

66193 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1

Details for RP23-161N17.10-001 - PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66193

Tuberculist Genomic Region

68118 RIKEN cDNA 9430023L20 gene

Details for - - RIKEN cDNA 9430023L20 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68118

Tuberculist Genomic Region

69807 tripartite motif-containing 32

Details for RP23-468K2.1 - tripartite motif-containing 32

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69807

Tuberculist Genomic Region

70381 tectonin beta-propeller repeat containing 1

Details for - - tectonin beta-propeller repeat containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70381

Tuberculist Genomic Region

72039 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)

Details for - - methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72039

Tuberculist Genomic Region

72144 solute carrier family 37 (glycerol-3-phosphate transporter), member 3

Details for - - solute carrier family 37 (glycerol-3-phosphate transporter), member 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72144

Tuberculist Genomic Region

74412 GLE1 RNA export mediator (yeast)

Details for RP23-443G7.5 - GLE1 RNA export mediator (yeast)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74412

Tuberculist Genomic Region

74653 protein-O-mannose kinase

Details for - - protein-O-mannose kinase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74653

Tuberculist Genomic Region

75735 pantothenate kinase 1

Details for - - pantothenate kinase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 75735

Tuberculist Genomic Region

16558 kinesin family member 16B

Details for RP23-442B16.1 - kinesin family member 16B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16558

Tuberculist Genomic Region

232196 expressed sequence C87436

Details for - - expressed sequence C87436

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 232196

Tuberculist Genomic Region

269180 inositol polyphosphate-4-phosphatase, type I

Details for - - inositol polyphosphate-4-phosphatase, type I

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 269180

Tuberculist Genomic Region

74360 centrosomal protein 57

Details for RP23-133A3.3 - centrosomal protein 57

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74360

Tuberculist Genomic Region

74551 phosphoenolpyruvate carboxykinase 2 (mitochondrial)

Details for - - phosphoenolpyruvate carboxykinase 2 (mitochondrial)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74551

Tuberculist Genomic Region

76608 HECT domain containing 3

Details for RP23-419D6.4 - HECT domain containing 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 76608

Tuberculist Genomic Region

94181 N-acetylneuraminic acid synthase (sialic acid synthase)

Details for RP23-117B19.4 - N-acetylneuraminic acid synthase (sialic acid synthase)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 94181

Tuberculist Genomic Region

140500 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3

Details for RP23-242K15.11-002 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 140500

Tuberculist Genomic Region

16319 inner centromere protein

Details for - - inner centromere protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16319

Tuberculist Genomic Region

84505 SET domain, bifurcated 1

Details for - - SET domain, bifurcated 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 84505

Tuberculist Genomic Region

17252 retinol dehydrogenase 11

Details for - - retinol dehydrogenase 11

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17252

Tuberculist Genomic Region

18861 postmeiotic segregation increased 2 (S. cerevisiae)

Details for - - postmeiotic segregation increased 2 (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18861

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
Etv5.1 0.409091 0.000000726

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.0000063 AAAYAAWAACAA FOXI1_MA0042.1, Foxa2.1, Foxk1.2, Zfp105.1, Foxj3.2, Foxl1.1, Foxk1.1, FOXJ2_forkhead_DBD_dimeric_13_1, Foxj3_forkhead_DBD_dimeric_13_1 0.0000042 KCCCCKCCCNCT SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_Q4_01_M00932, V$SP1_Q2_01_M00933, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$GC_01_M00255, V$SP4_Q5_M01273, V$SP1_03_M02281, V$KLF7_03_M02773, V$MAZ_Q6_01_M02023, V$SP4_03_M02810, V$GKLF_02_M01588, V$MAZR_01_M00491, V$ZFP281_01_M01597, V$CKROX_Q2_M01175, V$SP1_02_M01303, V$SP1_01_M00008, V$SMAD4_04_M02898, V$MAZ_Q6_M00649, V$SP2_01_M01783, V$ZFP740_03_M02834, V$ZBP89_Q4_M01816, V$UF1H3BETA_Q6_M01068, V$EGR1_Q6_M01873, V$SP1SP3_Q4_M01219, V$KROX_Q6_M00982, V$E2F3_Q6_M02089, V$EGR1_06_M02744, V$BCL6B_04_M02844, V$CACBINDINGPROTEIN_Q6_M00720, V$EGR_Q6_M00807, V$ZNF219_01_M01122, V$ZFP281_04_M02831, V$ZFP410_04_M02936, V$CACD_01_M01113, V$ASCL2_04_M02841, V$WT1_Q6_M01118, V$WT1_Q6_01_M02036, V$FKLF_Q5_M01837, V$ETF_Q6_M00695, V$EKLF_Q5_M01874, V$SOX14_04_M02901, V$FPM315_01_M01587, V$BTEB3_Q5_M01865, V$CTCF_01_M01200, V$KLF15_Q2_M01714, Klf7.1, Sp4.1, Smad3.1, Zfp740.1, Egr1.1, Bcl6b.2, Zfp281.2, Zfp410.1, Ascl2.2, Sox13.2, Zif268.1, Sp4.2, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, SP4_C2H2_full_monomeric_17_1, SP3_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, ZNF740_C2H2_full_monomeric_10_1, KLF13_C2H2_full_monomeric_18_1, Zfp740_C2H2_DBD_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.3 CGGCGT NA 1.43 TCGCGGAC NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.49 TCGCCG NA NA 0.51 GCNNGCAT NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-497 0.153846 0.0000235

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