TargetScan_31 megaCluster: 10 Residual: 0.16 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_31	10	0.16	15	0	0.958615	0

Members

Displaying 1 - 26 of 26

101739 PC4 and SFRS1 interacting protein 1 Details for RP23-311B24.4 - PC4 and SFRS1 interacting protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 101739 Tuberculist Genomic Region	104444 REX2, RNA exonuclease 2 homolog (S. cerevisiae) Details for - - REX2, RNA exonuclease 2 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104444 Tuberculist Genomic Region
12544 cell division cycle 45 Details for - - cell division cycle 45 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12544 Tuberculist Genomic Region	16319 inner centromere protein Details for - - inner centromere protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16319 Tuberculist Genomic Region
18971 polymerase (DNA directed), delta 1, catalytic subunit Details for - - polymerase (DNA directed), delta 1, catalytic subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18971 Tuberculist Genomic Region	20873 polo-like kinase 4 Details for - - polo-like kinase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20873 Tuberculist Genomic Region
21749 telomeric repeat binding factor 1 Details for - - telomeric repeat binding factor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21749 Tuberculist Genomic Region	22248 unc-119 homolog (C. elegans) Details for RP23-185A18.16-002 - unc-119 homolog (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22248 Tuberculist Genomic Region
27878 transcriptional adaptor 1 Details for - - transcriptional adaptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27878 Tuberculist Genomic Region	66131 timeless interacting protein Details for - - timeless interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66131 Tuberculist Genomic Region
66634 minichromosome maintenance deficient 8 (S. cerevisiae) Details for RP23-77H16.3 - minichromosome maintenance deficient 8 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66634 Tuberculist Genomic Region	66953 cell division cycle associated 7 Details for RP23-146F24.2 - cell division cycle associated 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66953 Tuberculist Genomic Region
67872 non-SMC element 4 homolog A (S. cerevisiae) Details for - - non-SMC element 4 homolog A (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67872 Tuberculist Genomic Region	68201 coiled-coil domain containing 34 Details for RP23-300M9.1 - coiled-coil domain containing 34 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68201 Tuberculist Genomic Region
69724 ribonuclease H2, large subunit Details for - - ribonuclease H2, large subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69724 Tuberculist Genomic Region	70238 ring finger protein 168 Details for - - ring finger protein 168 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70238 Tuberculist Genomic Region
71876 centromere protein U Details for - - centromere protein U GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71876 Tuberculist Genomic Region	20492 stem-loop binding protein Details for - - stem-loop binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20492 Tuberculist Genomic Region
56427 tubulin, delta 1 Details for RP23-467J12.3 - tubulin, delta 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56427 Tuberculist Genomic Region	76832 hydrolethalus syndrome 1 Details for - - hydrolethalus syndrome 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76832 Tuberculist Genomic Region
12545 cell division cycle 7 (S. cerevisiae) Details for - - cell division cycle 7 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12545 Tuberculist Genomic Region	16881 ligase I, DNA, ATP-dependent Details for - - ligase I, DNA, ATP-dependent GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16881 Tuberculist Genomic Region
17688 mutS homolog 6 (E. coli) Details for - - mutS homolog 6 (E. coli) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17688 Tuberculist Genomic Region	19075 DNA primase, p49 subunit Details for - - DNA primase, p49 subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19075 Tuberculist Genomic Region
230376 HAUS augmin-like complex, subunit 6 Details for RP23-95O1.3 - HAUS augmin-like complex, subunit 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230376 Tuberculist Genomic Region	52504 centromere protein O Details for RP23-6C18.1 - centromere protein O GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52504 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
E2F8_E2F_DBD_dimeric_12_1	0.461538	0.00000000498

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000009	TTTTNTTTTTT	NA	3300	NGCCCCGCCCC	Klf4_MA0039.2, SP1_MA0079.2, V$SP4_Q5_M01273, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$SP1_02_M01303, V$SP1_Q4_01_M00932, V$KLF7_03_M02773, V$GC_01_M00255, V$SP4_03_M02810, V$UF1H3BETA_Q6_M01068, V$SP1_Q2_01_M00933, V$GKLF_02_M01588, V$ZFP281_01_M01597, V$SP2_01_M01783, V$SP1_03_M02281, V$MAZR_01_M00491, V$CKROX_Q2_M01175, V$CACD_01_M01113, V$E2F3_Q6_M02089, V$MAZ_Q6_M00649, V$SP1_01_M00008, V$BCL6B_04_M02844, V$KROX_Q6_M00982, V$SMAD4_04_M02898, V$EGR1_06_M02744, V$ZFP281_04_M02831, V$EGR1_Q6_M01873, V$CNOT3_01_M01253, V$ZFP410_04_M02936, V$ZBP89_Q4_M01816, V$FKLF_Q5_M01837, V$KLF15_Q2_M01714, V$E2F_Q2_M00803, V$EKLF_Q5_M01874, V$ETF_Q6_M00695, V$SP4_04_M02914, Klf7.1, Sp4.1, Bcl6b.2, Egr1.1, Smad3.1, Zfp281.2, Zfp410.1, Sp4.2, Zfp740.1, Ascl2.2, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, KLF13_C2H2_full_monomeric_18_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, Klf12_C2H2_DBD_monomeric_15_1, SP8_C2H2_DBD_monomeric_12_1, SP3_C2H2_DBD_monomeric_11_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.37	TGGCGG	V$SMAD4_04_M02898, Smad3.1, E2F8_E2F_DBD_dimeric_12_1, YY2_C2H2_full_dimeric_12_1	1.55	ACGCGCCA	V$E2F_Q2_M00803, Smad3.1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.63	GTAAGT	NA	NA	0.73	TTCAGGTA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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