TargetScan_64 megaCluster: 2 Residual: 0.15 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_64	2	0.15	15	0	0.950668	0

Members

Displaying 1 - 21 of 21

16164 interleukin 13 receptor, alpha 1 Details for RP23-132G2.1 - interleukin 13 receptor, alpha 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16164 Tuberculist Genomic Region	16452 Janus kinase 2 Details for - - Janus kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16452 Tuberculist Genomic Region
16648 karyopherin (importin) alpha 3 Details for - - karyopherin (importin) alpha 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16648 Tuberculist Genomic Region	17135 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) Details for - - v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17135 Tuberculist Genomic Region
17355 AF4/FMR2 family, member 1 Details for AL731554.2 - AF4/FMR2 family, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17355 Tuberculist Genomic Region	17357 MARCKS-like 1 Details for RP23-209C6.6 - MARCKS-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17357 Tuberculist Genomic Region
17857 myxovirus (influenza virus) resistance 1 Details for - - myxovirus (influenza virus) resistance 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17857 Tuberculist Genomic Region	19730 ral guanine nucleotide dissociation stimulator Details for RP23-430H1.6 - ral guanine nucleotide dissociation stimulator GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19730 Tuberculist Genomic Region
21417 zinc finger E-box binding homeobox 1 Details for - - zinc finger E-box binding homeobox 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21417 Tuberculist Genomic Region	215257 interleukin 1 family, member 9 Details for RP23-176J12.3 - interleukin 1 family, member 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 215257 Tuberculist Genomic Region
22778 IKAROS family zinc finger 1 Details for RP23-373H2.2 - IKAROS family zinc finger 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22778 Tuberculist Genomic Region	338523 lysine (K)-specific demethylase 7A Details for - - lysine (K)-specific demethylase 7A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 338523 Tuberculist Genomic Region
383619 absent in melanoma 2 Details for - - absent in melanoma 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 383619 Tuberculist Genomic Region	627049 zinc finger protein 800 Details for - - zinc finger protein 800 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 627049 Tuberculist Genomic Region
80885 niacin receptor 1 Details for - - niacin receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80885 Tuberculist Genomic Region	12515 CD69 antigen Details for - - CD69 antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12515 Tuberculist Genomic Region
13163 Fas death domain-associated protein Details for - - Fas death domain-associated protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13163 Tuberculist Genomic Region	66205 CD302 antigen Details for RP23-10L17.2 - CD302 antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66205 Tuberculist Genomic Region
66674 SPRY domain containing 7 Details for RP23-38F20.1 - SPRY domain containing 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66674 Tuberculist Genomic Region	74646 splA/ryanodine receptor domain and SOCS box containing 1 Details for RP23-169H13.1 - splA/ryanodine receptor domain and SOCS box containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74646 Tuberculist Genomic Region
54199 chemokine (C-C motif) receptor-like 2 Details for - - chemokine (C-C motif) receptor-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54199 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
EGR2_C2H2_full_monomeric_15_1	0.809524	0.00000996

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
300	CCGCCCCGCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, V$SP1_03_M02281, V$SP1_02_M01303, V$SP1_Q6_M00196, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP1_Q2_01_M00933, V$ZNF219_01_M01122, V$ZFP281_01_M01597, V$KLF7_03_M02773, V$UF1H3BETA_Q6_M01068, V$MAZR_01_M00491, V$GKLF_02_M01588, V$KROX_Q6_M00982, V$CKROX_Q2_M01175, V$ZFP281_04_M02831, V$SP2_01_M01783, V$MAZ_Q6_01_M02023, V$ZFP410_04_M02936, V$BCL6B_04_M02844, V$CACD_01_M01113, V$SMAD4_04_M02898, V$KLF15_Q2_M01714, V$SP1_01_M00008, V$EGR1_06_M02744, V$EGR1_Q6_M01873, V$MAZ_Q6_M00649, V$SP1SP3_Q4_M01219, V$ETF_Q6_M00695, V$WT1_Q6_01_M02036, V$ZFP740_03_M02834, V$SP4_03_M02810, V$ZBP89_Q4_M01816, V$ASCL2_04_M02841, V$FKLF_Q5_M01837, Klf7.1, Zfp281.2, Zfp410.1, Bcl6b.2, Smad3.1, Egr1.1, Zfp740.1, Sp4.1, Ascl2.2, Glis2.1, Myf6.1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, ZNF740_C2H2_full_monomeric_10_1, SP8_C2H2_DBD_monomeric_12_1, Zfp740_C2H2_DBD_monomeric_10_1	810	ATCTTTWAAMAA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.4	CCGACG	NA	1.59	GNCTCCGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.61	ACGCCG	NA	NA	0.98	AAACGCCG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-1264-3p	0.611111	0.0000064

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