TargetScan_89 megaCluster: 11 Residual: 0.23 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_89	11	0.23	15	0	0.901941	0

Members

Displaying 1 - 37 of 37

100972 RAB28, member RAS oncogene family Details for - - RAB28, member RAS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100972 Tuberculist Genomic Region	15182 histone deacetylase 2 Details for - - histone deacetylase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15182 Tuberculist Genomic Region
15510 heat shock protein 1 (chaperonin) Details for - - heat shock protein 1 (chaperonin) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15510 Tuberculist Genomic Region	19286 6-pyruvoyl-tetrahydropterin synthase Details for - - 6-pyruvoyl-tetrahydropterin synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19286 Tuberculist Genomic Region
20018 polymerase (RNA) I polypeptide D Details for AL513345.2 - polymerase (RNA) I polypeptide D GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20018 Tuberculist Genomic Region	20813 signal recognition particle 14 Details for RP23-450P9.3 - signal recognition particle 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20813 Tuberculist Genomic Region
22099 translin Details for - - translin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22099 Tuberculist Genomic Region	52705 KRR1, small subunit (SSU) processome component, homolog (yeast) Details for - - KRR1, small subunit (SSU) processome component, homolog (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52705 Tuberculist Genomic Region
53415 HIV-1 tat interactive protein 2, homolog (human) Details for - - HIV-1 tat interactive protein 2, homolog (human) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53415 Tuberculist Genomic Region	56372 RIKEN cDNA 1110004F10 gene Details for - - RIKEN cDNA 1110004F10 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56372 Tuberculist Genomic Region
57423 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 Details for - - ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57423 Tuberculist Genomic Region	58521 EP300 interacting inhibitor of differentiation 1 Details for RP23-323D9.2 - EP300 interacting inhibitor of differentiation 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 58521 Tuberculist Genomic Region
65113 Nedd4 family interacting protein 1 Details for - - Nedd4 family interacting protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 65113 Tuberculist Genomic Region	66591 MAD2L1 binding protein Details for - - MAD2L1 binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66591 Tuberculist Genomic Region
66911 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 Details for - - nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66911 Tuberculist Genomic Region	67089 proteasome (prosome, macropain) 26S subunit, ATPase, 6 Details for - - proteasome (prosome, macropain) 26S subunit, ATPase, 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67089 Tuberculist Genomic Region
67418 peptidylprolyl isomerase (cyclophilin)-like 4 Details for - - peptidylprolyl isomerase (cyclophilin)-like 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67418 Tuberculist Genomic Region	68153 general transcription factor II E, polypeptide 2 (beta subunit) Details for - - general transcription factor II E, polypeptide 2 (beta subunit) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68153 Tuberculist Genomic Region
69790 mediator complex subunit 30 Details for - - mediator complex subunit 30 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69790 Tuberculist Genomic Region	75614 RAB26, member RAS oncogene family, opposite strand Details for - - RAB26, member RAS oncogene family, opposite strand GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75614 Tuberculist Genomic Region
78523 mitochondrial ribosomal protein L9 Details for - - mitochondrial ribosomal protein L9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78523 Tuberculist Genomic Region	106821 O-acyl-ADP-ribose deacylase 1 Details for - - O-acyl-ADP-ribose deacylase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106821 Tuberculist Genomic Region
192169 UFM1-specific peptidase 2 Details for - - UFM1-specific peptidase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192169 Tuberculist Genomic Region	209354 eukaryotic translation initiation factor 2B, subunit 1 (alpha) Details for - - eukaryotic translation initiation factor 2B, subunit 1 (alpha) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209354 Tuberculist Genomic Region
225160 THO complex 1 Details for - - THO complex 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225160 Tuberculist Genomic Region	66799 ubiquitin-conjugating enzyme E2W (putative) Details for - - ubiquitin-conjugating enzyme E2W (putative) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66799 Tuberculist Genomic Region
67013 OMA1 homolog, zinc metallopeptidase (S. cerevisiae) Details for RP23-47A6.4 - OMA1 homolog, zinc metallopeptidase (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67013 Tuberculist Genomic Region	67422 dehydrodolichyl diphosphate synthase Details for RP23-256C7.6 - dehydrodolichyl diphosphate synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67422 Tuberculist Genomic Region
69871 protein phosphatase 1, regulatory subunit 35 Details for - - protein phosphatase 1, regulatory subunit 35 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69871 Tuberculist Genomic Region	74326 heterogeneous nuclear ribonucleoprotein R Details for RP24-315O23.1 - heterogeneous nuclear ribonucleoprotein R GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74326 Tuberculist Genomic Region
78935 serum amyloid A-like 1 Details for - - serum amyloid A-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78935 Tuberculist Genomic Region	105446 guanosine monophosphate reductase 2 Details for - - guanosine monophosphate reductase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 105446 Tuberculist Genomic Region
14227 FK506 binding protein 2 Details for - - FK506 binding protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14227 Tuberculist Genomic Region	66880 arginine/serine-rich coiled-coil 1 Details for - - arginine/serine-rich coiled-coil 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66880 Tuberculist Genomic Region
69554 kelch domain containing 2 Details for - - kelch domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69554 Tuberculist Genomic Region	13682 eukaryotic translation initiation factor 4A2 Details for - - eukaryotic translation initiation factor 4A2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13682 Tuberculist Genomic Region
19182 proteasome (prosome, macropain) 26S subunit, ATPase 3 Details for RP23-263H8.1 - proteasome (prosome, macropain) 26S subunit, ATPase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19182 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_SP1SP3_Q4_M01219	0.972222	0.00000274

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.00000000015	AAAARAAAAA	NA	5.9	GCYCCGCCCCCY	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_Q6_M00196, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$SP4_03_M02810, V$SP1_03_M02281, V$SP4_Q5_M01273, V$SP1SP3_Q4_M01219, V$SP2_01_M01783, V$ZFP281_01_M01597, V$SP1_01_M00008, V$UF1H3BETA_Q6_M01068, V$EGR1_Q6_M01873, V$KLF7_03_M02773, V$SP1_02_M01303, V$EGR1_06_M02744, V$ETF_Q6_M00695, V$KROX_Q6_M00982, V$MAZ_Q6_01_M02023, V$GKLF_02_M01588, V$SMAD4_04_M02898, V$ZBP89_Q4_M01816, V$E2F3_Q6_M02089, V$MAZR_01_M00491, V$ZFP281_04_M02831, V$BCL6B_04_M02844, V$WT1_Q6_01_M02036, V$ZFP410_04_M02936, V$ZNF219_01_M01122, V$RNF96_01_M01199, V$ZFP740_03_M02834, V$EGR_Q6_M00807, Sp4.1, Klf7.1, Egr1.1, Smad3.1, Zfp281.2, Bcl6b.2, Zfp410.1, Zfp740.1, Sp4.2, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, SP3_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.53	ACGCCG	NA	1.68	CTTCGGCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.58	NGGTTATA	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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