Brca1 breast cancer 1 (12189) | Macrophage Network Portal

Summary

	Symbol	Product	Feature Type	Strand	Chr
12189	Brca1	breast cancer 1	protein-coding		11

Synonyms

Synonyms
-

DB XRef

Ensembl	MGI	VEGA
ENSMUSG00000017146	MGI:104537	OTTMUSG00000002870

GO Terms

GO ID	Category	Definition	Evidence
GO:0000724 GO:0000793 GO:0000794 GO:0001726 GO:0003677 GO:0003684 GO:0003723 GO:0004842 GO:0005634 GO:0005694 GO:0005737 GO:0005759 GO:0005813 GO:0005886 GO:0005925 GO:0006260 GO:0006281 GO:0006301 GO:0006302 GO:0006310 GO:0006349 GO:0006629 GO:0006631 GO:0006633 GO:0006974 GO:0007049 GO:0007059 GO:0007098 GO:0008270 GO:0008630 GO:0009048 GO:0010212 GO:0016567 GO:0016874 GO:0019899 GO:0030529 GO:0031398 GO:0031436 GO:0031572 GO:0031625 GO:0031941 GO:0034446 GO:0035066 GO:0035067 GO:0043009 GO:0043234 GO:0043627 GO:0044030 GO:0044212 GO:0045717 GO:0045739 GO:0045892 GO:0045944 GO:0046872 GO:0051298 GO:0051571 GO:0051572 GO:0051573 GO:0051574 GO:0051865 GO:0070512 GO:0070531 GO:0071158 GO:0071681 GO:0085020 GO:2000145 GO:2000617 GO:2000620	Process Component Function	double-strand break repair via homologous recombination condensed chromosome condensed nuclear chromosome ruffle DNA binding damaged DNA binding RNA binding ubiquitin-protein ligase activity nucleus chromosome cytoplasm mitochondrial matrix centrosome plasma membrane focal adhesion DNA replication DNA repair postreplication repair double-strand break repair DNA recombination regulation of gene expression by genetic imprinting lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process cellular response to DNA damage stimulus cell cycle chromosome segregation centrosome cycle zinc ion binding intrinsic apoptotic signaling pathway in response to DNA damage dosage compensation by inactivation of X chromosome response to ionizing radiation protein ubiquitination ligase activity enzyme binding ribonucleoprotein complex positive regulation of protein ubiquitination BRCA1-BARD1 complex G2 DNA damage checkpoint ubiquitin protein ligase binding filamentous actin substrate adhesion-dependent cell spreading positive regulation of histone acetylation negative regulation of histone acetylation chordate embryonic development protein complex response to estrogen regulation of DNA methylation transcription regulatory region DNA binding negative regulation of fatty acid biosynthetic process positive regulation of DNA repair negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter metal ion binding centrosome duplication positive regulation of histone H3-K4 methylation negative regulation of histone H3-K4 methylation negative regulation of histone H3-K9 methylation positive regulation of histone H3-K9 methylation protein autoubiquitination positive regulation of histone H4-K20 methylation BRCA1-A complex positive regulation of cell cycle arrest cellular response to indole-3-methanol protein K6-linked ubiquitination regulation of cell motility positive regulation of histone H3-K9 acetylation positive regulation of histone H4-K16 acetylation	ISO IDA IEA TAS IMP IGI

Regulatory Modules

	Motif 1	Motif 2	Residual
PITA_129 \| PITA_129 Residual: 0.13			0.13
PITA_196 \| PITA_196 Residual: 0.19			0.19
PITA_2 \| PITA_2 Residual: 0.15			0.15
TargetScan_104 \| TargetScan_104 Residual: 0.17			0.17
TargetScan_115 \| TargetScan_115 Residual: 0.14			0.14
TargetScan_138 \| TargetScan_138 Residual: 0.64			0.64

Regulation

Displaying 1 - 6 of 6

Regulator Locus	Interaction	Weight

String Network

Entrez ID	STRINGS Network
STRING

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