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- regulation of cyclin-dependent protein serine/threonine kinase activity
- G1/S transition of mitotic cell cycle
- G2/M transition of mitotic cell cycle
- cyclin-dependent protein kinase holoenzyme complex
- protein kinase inhibitor activity
- cyclin-dependent protein serine/threonine kinase inhibitor activity
- protein binding
- intracellular
- nucleus
- cytoplasm
- cytosol
- protein phosphorylation
- cellular response to DNA damage stimulus
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
- cell cycle
- cell cycle arrest
- regulation of mitotic cell cycle
- negative regulation of cell proliferation
- response to UV
- negative regulation of gene expression
- kinase activity
- phosphorylation
- transferase activity
- cyclin-dependent protein kinase activating kinase activity
- negative regulation of cell growth
- cyclin binding
- positive regulation of B cell proliferation
- cellular response to extracellular stimulus
- protein complex binding
- regulation of protein import into nucleus, translocation
- negative regulation of phosphorylation
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
- negative regulation of apoptotic process
- positive regulation of programmed cell death
- negative regulation of cyclin-dependent protein serine/threonine kinase activity
- positive regulation of protein kinase activity
- metal ion binding
- positive regulation of fibroblast proliferation
- regulation of cell cycle
- PCNA-p21 complex
- cellular response to ionizing radiation
- mitotic cell cycle arrest
- cellular senescence
- regulation of DNA biosynthetic process
- positive regulation of reactive oxygen species metabolic process
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