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- activation of MAPKKK activity
- core promoter binding
- protein binding
- nucleus
- cytoplasm
- negative regulation of protein kinase activity
- response to stress
- cellular response to DNA damage stimulus
- cell cycle
- cell cycle arrest
- centrosome cycle
- signal transduction in response to DNA damage
- positive regulation of apoptotic process
- positive regulation of JNK cascade
- regulation of cell cycle
- cellular response to ionizing radiation
- positive regulation of p38MAPK cascade
- positive regulation of reactive oxygen species metabolic process
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