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- ubiquitin-protein ligase activity
- protein binding
- nucleus
- cytoplasm
- early endosome
- cytosol
- plasma membrane
- ubiquitin-dependent protein catabolic process
- apoptotic process
- cell cycle
- male meiosis I
- multicellular organismal development
- spermatogenesis
- protein C-terminus binding
- zinc ion binding
- post-embryonic development
- protein ubiquitination
- ligase activity
- cell differentiation
- protein catabolic process
- beta-catenin destruction complex
- protein destabilization
- regulation of multicellular organism growth
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process
- protein homodimerization activity
- positive regulation of apoptotic process
- proteasome-mediated ubiquitin-dependent protein catabolic process
- metal ion binding
- neuron apoptotic process
- positive regulation of intrinsic apoptotic signaling pathway
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