Tgfb1 transforming growth factor, beta 1 (21803)

Symbol Product Feature Type Strand Chr
21803 Tgfb1 transforming growth factor, beta 1 protein-coding 7
Synonyms
TGF-beta1 | TGFbeta1 | Tgfb | Tgfb-1
GO ID Category Definition Evidence
  • protein import into nucleus, translocation
  • negative regulation of transcription from RNA polymerase II promoter
  • MAPK cascade
  • skeletal system development
  • morphogenesis of a branching structure
  • cell activation
  • epithelial to mesenchymal transition
  • negative regulation of protein phosphorylation
  • positive regulation of protein phosphorylation
  • regulation of sodium ion transport
  • chondrocyte differentiation
  • hematopoietic progenitor cell differentiation
  • adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
  • tolerance induction to self antigen
  • type II transforming growth factor beta receptor binding
  • transforming growth factor beta receptor binding
  • protein binding
  • extracellular region
  • proteinaceous extracellular matrix
  • extracellular space
  • nucleus
  • cytoplasm
  • microvillus
  • protein phosphorylation
  • protein export from nucleus
  • ATP biosynthetic process
  • phosphate-containing compound metabolic process
  • cellular calcium ion homeostasis
  • defense response
  • inflammatory response
  • cell cycle arrest
  • mitotic cell cycle checkpoint
  • epidermal growth factor receptor signaling pathway
  • transforming growth factor beta receptor signaling pathway
  • common-partner SMAD protein phosphorylation
  • SMAD protein complex assembly
  • SMAD protein import into nucleus
  • negative regulation of neuroblast proliferation
  • endoderm development
  • skeletal muscle tissue development
  • growth factor activity
  • negative regulation of DNA replication
  • cell death
  • cell proliferation
  • positive regulation of cell proliferation
  • negative regulation of cell proliferation
  • germ cell migration
  • defense response to fungus, incompatible interaction
  • organ morphogenesis
  • cell surface
  • response to organic substance
  • positive regulation of gene expression
  • positive regulation of epithelial to mesenchymal transition
  • positive regulation of fibroblast migration
  • positive regulation of peptidyl-threonine phosphorylation
  • positive regulation of pathway-restricted SMAD protein phosphorylation
  • negative regulation of macrophage cytokine production
  • cell growth
  • regulation of striated muscle tissue development
  • regulation of transforming growth factor beta receptor signaling pathway
  • evasion or tolerance of host defenses by virus
  • enzyme binding
  • negative regulation of cell-cell adhesion
  • secretory granule
  • hyaluronan catabolic process
  • T cell differentiation
  • negative regulation of ossification
  • negative regulation of cell growth
  • positive regulation of cell migration
  • axon
  • mammary gland development
  • extracellular matrix
  • positive regulation of histone deacetylation
  • organ regeneration
  • positive regulation of protein complex assembly
  • positive regulation of exit from mitosis
  • lipopolysaccharide-mediated signaling pathway
  • positive regulation of cellular protein metabolic process
  • response to estradiol
  • response to progesterone
  • positive regulation of interleukin-17 production
  • receptor catabolic process
  • positive regulation of superoxide anion generation
  • mononuclear cell proliferation
  • positive regulation of collagen biosynthetic process
  • positive regulation of peptidyl-serine phosphorylation
  • positive regulation of histone acetylation
  • positive regulation of protein dephosphorylation
  • growth
  • wound healing
  • T cell activation
  • regulation of cell proliferation
  • negative regulation of T cell proliferation
  • regulation of protein import into nucleus
  • positive regulation of protein import into nucleus
  • positive regulation of odontogenesis
  • myelination
  • protein homodimerization activity
  • myeloid dendritic cell differentiation
  • neuronal cell body
  • T cell homeostasis
  • positive regulation of apoptotic process
  • positive regulation of MAP kinase activity
  • protein kinase B signaling
  • positive regulation of blood vessel endothelial cell migration
  • negative regulation of blood vessel endothelial cell migration
  • positive regulation of phosphatidylinositol 3-kinase activity
  • regulatory T cell differentiation
  • cell-cell junction organization
  • negative regulation of fat cell differentiation
  • negative regulation of myoblast differentiation
  • negative regulation of cell cycle
  • negative regulation of transcription, DNA-templated
  • positive regulation of transcription, DNA-templated
  • negative regulation of mitotic cell cycle
  • positive regulation of transcription from RNA polymerase II promoter
  • protein heterodimerization activity
  • protein N-terminus binding
  • positive regulation of isotype switching to IgA isotypes
  • lymph node development
  • negative regulation of skeletal muscle tissue development
  • positive regulation of epithelial cell proliferation
  • negative regulation of epithelial cell proliferation
  • positive regulation of protein secretion
  • negative regulation of phagocytosis
  • negative regulation of immune response
  • negative regulation of T cell activation
  • positive regulation of chemotaxis
  • positive regulation of NF-kappaB transcription factor activity
  • regulation of binding
  • regulation of DNA binding
  • positive regulation of smooth muscle cell differentiation
  • negative regulation of release of sequestered calcium ion into cytosol
  • positive regulation of cell division
  • positive regulation of protein kinase B signaling
  • pathway-restricted SMAD protein phosphorylation
  • positive regulation of SMAD protein import into nucleus
  • mammary gland branching involved in thelarche
  • branch elongation involved in mammary gland duct branching
  • regulation of branching involved in mammary gland duct morphogenesis
  • regulation of cartilage development
  • lens fiber cell differentiation
  • response to cholesterol
  • positive regulation of cell cycle arrest
  • cellular response to growth factor stimulus
  • cellular response to organic cyclic compound
  • cellular response to dexamethasone stimulus
  • extracellular matrix assembly
  • positive regulation of branching involved in ureteric bud morphogenesis
  • extrinsic apoptotic signaling pathway
  • negative regulation of hyaluronan biosynthetic process
  • positive regulation of protein localization to nucleus
  • positive regulation of NAD+ ADP-ribosyltransferase activity
  • regulation of actin cytoskeleton reorganization
  • positive regulation of transcription regulatory region DNA binding
Motif 1 Motif 2 Residual
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Entrez ID STRINGS Network
STRING
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