Trp53 transformation related protein 53 (22059)

Symbol Product Feature Type Strand Chr
22059 Trp53 transformation related protein 53 protein-coding 11
Synonyms
Tp53 | bbl | bfy | bhy | p44 | p53
GO ID Category Definition Evidence
  • protein import into nucleus, translocation
  • negative regulation of transcription from RNA polymerase II promoter
  • DNA strand renaturation
  • chromatin
  • nuclear chromatin
  • RNA polymerase II core promoter sequence-specific DNA binding
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
  • RNA polymerase II transcription factor binding
  • transcription cofactor binding
  • RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
  • in utero embryonic development
  • somitogenesis
  • release of cytochrome c from mitochondria
  • protease binding
  • p53 binding
  • T cell proliferation involved in immune response
  • B cell lineage commitment
  • T cell lineage commitment
  • positive regulation of leukocyte migration
  • response to ischemia
  • DNA binding
  • chromatin binding
  • damaged DNA binding
  • double-stranded DNA binding
  • sequence-specific DNA binding transcription factor activity
  • copper ion binding
  • protein binding
  • ATP binding
  • intracellular
  • nucleus
  • nucleoplasm
  • replication fork
  • transcription factor complex
  • transcription factor TFIID complex
  • nucleolus
  • cytoplasm
  • mitochondrion
  • mitochondrial matrix
  • endoplasmic reticulum
  • cytosol
  • nucleotide-excision repair
  • double-strand break repair
  • transcription, DNA-templated
  • regulation of transcription, DNA-templated
  • transcription from RNA polymerase II promoter
  • protein complex assembly
  • apoptotic process
  • cellular response to DNA damage stimulus
  • DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
  • DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
  • response to oxidative stress
  • ER overload response
  • cell cycle
  • cell cycle arrest
  • transforming growth factor beta receptor signaling pathway
  • multicellular organismal development
  • gastrulation
  • negative regulation of neuroblast proliferation
  • central nervous system development
  • cell aging
  • protein C-terminus binding
  • protein localization
  • transcription factor binding
  • negative regulation of DNA replication
  • negative regulation of cell proliferation
  • determination of adult lifespan
  • rRNA transcription
  • response to UV
  • response to salt stress
  • embryo development ending in birth or egg hatching
  • response to X-ray
  • response to gamma radiation
  • positive regulation of cardiac muscle cell apoptotic process
  • programmed cell death
  • nuclear matrix
  • nuclear body
  • PML body
  • enzyme binding
  • protein kinase binding
  • negative regulation of cell growth
  • DNA damage response, signal transduction by p53 class mediator
  • negative regulation of transforming growth factor beta receptor signaling pathway
  • receptor tyrosine kinase binding
  • positive regulation of histone deacetylation
  • chromatin assembly
  • mitotic G1 DNA damage checkpoint
  • ubiquitin protein ligase binding
  • positive regulation of protein oligomerization
  • T cell differentiation in thymus
  • regulation of tissue remodeling
  • cellular protein localization
  • cellular response to UV
  • histone deacetylase regulator activity
  • histone acetyltransferase binding
  • multicellular organism growth
  • positive regulation of mitochondrial membrane permeability
  • regulation of cell proliferation
  • cellular response to glucose starvation
  • response to drug
  • intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
  • identical protein binding
  • regulation of apoptotic process
  • positive regulation of apoptotic process
  • negative regulation of apoptotic process
  • protein complex
  • regulation of neuron apoptotic process
  • positive regulation of neuron apoptotic process
  • sequence-specific DNA binding
  • transcription regulatory region DNA binding
  • positive regulation of cell cycle
  • negative regulation of transcription, DNA-templated
  • positive regulation of transcription, DNA-templated
  • positive regulation of transcription from RNA polymerase II promoter
  • metal ion binding
  • protein heterodimerization activity
  • protein N-terminus binding
  • negative regulation of fibroblast proliferation
  • embryonic organ development
  • negative regulation of smooth muscle cell proliferation
  • positive regulation of peptidyl-tyrosine phosphorylation
  • regulation of catalytic activity
  • chaperone binding
  • protein tetramerization
  • chromosome organization
  • neuron apoptotic process
  • regulation of intracellular pH
  • protein phosphatase 2A binding
  • regulation of cell cycle
  • regulation of thymocyte apoptotic process
  • positive regulation of thymocyte apoptotic process
  • necroptotic process
  • positive regulation of cell cycle arrest
  • cellular response to ionizing radiation
  • mitotic cell cycle arrest
  • intrinsic apoptotic signaling pathway by p53 class mediator
  • positive regulation of release of cytochrome c from mitochondria
  • positive regulation of cell aging
  • replicative senescence
  • oxidative stress-induced premature senescence
  • oligodendrocyte apoptotic process
  • MDM2/MDM4 family protein binding
  • negative regulation of macromitophagy
  • regulation of mitochondrial membrane permeability involved in apoptotic process
  • negative regulation of DNA biosynthetic process
  • negative regulation of reactive oxygen species metabolic process
  • positive regulation of reactive oxygen species metabolic process
  • positive regulation of intrinsic apoptotic signaling pathway
Motif 1 Motif 2 Residual
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Entrez ID STRINGS Network
STRING
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