Park2 Parkinson disease (autosomal recessive, juvenile) 2, parkin (50873)

Symbol Product Feature Type Strand Chr
50873 Park2 Parkinson disease (autosomal recessive, juvenile) 2, parkin protein-coding 17
Synonyms
PRKN
Ensembl MGI VEGA
NA MGI:1355296 NA
GO ID Category Definition Evidence
  • Golgi membrane
  • protein polyubiquitination
  • mitochondrion degradation
  • negative regulation of protein phosphorylation
  • synaptic transmission, dopaminergic
  • startle response
  • ubiquitin-protein ligase activity
  • protein binding
  • intracellular
  • nucleus
  • cytoplasm
  • mitochondrion
  • endoplasmic reticulum
  • Golgi apparatus
  • cytosol
  • plasma membrane
  • transcription, DNA-templated
  • regulation of transcription, DNA-templated
  • ubiquitin-dependent protein catabolic process
  • protein monoubiquitination
  • autophagy
  • response to unfolded protein
  • learning
  • locomotory behavior
  • synaptic vesicle
  • cell death
  • zinc ion binding
  • adult locomotory behavior
  • regulation of autophagy
  • postsynaptic density
  • membrane
  • aggresome
  • protein ubiquitination
  • ligase activity
  • acid-amino acid ligase activity
  • protein metabolic process
  • kinase binding
  • protein kinase binding
  • cell junction
  • PDZ domain binding
  • cytoplasmic vesicle
  • ubiquitin protein ligase binding
  • negative regulation of actin filament bundle assembly
  • protein complex binding
  • synaptic transmission, glutamatergic
  • norepinephrine metabolic process
  • dopamine metabolic process
  • protein ubiquitination involved in ubiquitin-dependent protein catabolic process
  • identical protein binding
  • cell projection
  • neuron projection
  • positive regulation of I-kappaB kinase/NF-kappaB signaling
  • protein complex
  • negative regulation of neuron apoptotic process
  • membrane raft
  • synapse
  • postsynaptic membrane
  • metal ion binding
  • regulation of neurotransmitter secretion
  • perinuclear region of cytoplasm
  • regulation of synaptic transmission
  • chaperone binding
  • dopamine uptake involved in synaptic transmission
  • protein autoubiquitination
  • negative regulation of cell death
  • protein K63-linked ubiquitination
  • aggresome assembly
  • protein K48-linked ubiquitination
  • neuron death
  • negative regulation of release of cytochrome c from mitochondria
  • regulation of reactive oxygen species metabolic process
Motif 1 Motif 2 Residual
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Entrez ID STRINGS Network
STRING
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