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- nucleotide binding
- activation of MAPKK activity
- protein kinase activity
- protein serine/threonine kinase activity
- MAP kinase kinase kinase activity
- ATP binding
- cytoplasm
- protein phosphorylation
- JNK cascade
- IkappaB kinase complex
- membrane
- kinase activity
- phosphorylation
- transferase activity
- transferase activity, transferring phosphorus-containing groups
- identical protein binding
- protein homodimerization activity
- protein autophosphorylation
- metal ion binding
- positive regulation of NF-kappaB transcription factor activity
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