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- protein polyubiquitination
- ubiquitin-protein ligase activity
- nucleus
- cytoplasm
- plasma membrane
- protein export from nucleus
- transforming growth factor beta receptor signaling pathway
- membrane
- protein ubiquitination
- ligase activity
- cell differentiation
- negative regulation of ossification
- axon
- BMP signaling pathway
- negative regulation of transforming growth factor beta receptor signaling pathway
- ubiquitin-dependent SMAD protein catabolic process
- receptor catabolic process
- protein localization to cell surface
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process
- neuronal cell body
- proteasome-mediated ubiquitin-dependent protein catabolic process
- I-SMAD binding
- R-SMAD binding
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