|  |  | nucleotide bindingtranscription corepressor activityprotein kinase activityprotein serine/threonine kinase activityMAP kinase kinase kinase activityprotein bindingATP bindingcytoplasmprotein phosphorylationsmoothened signaling pathwaycell deathkinase activityphosphorylationtransferase activitytransferase activity, transferring phosphorus-containing groupspeptidyl-serine phosphorylationpeptidyl-threonine phosphorylationpositive regulation of apoptotic processbHLH transcription factor bindingnegative regulation of sequence-specific DNA binding transcription factor activitypositive regulation of JUN kinase activitynegative regulation of transcription, DNA-templatedpositive regulation of JNK cascade
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