GO:0008440

inositol-1,4,5-trisphosphate 3-kinase activity

Details: 
Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+). [EC:2.7.1.127, RHEA:11023]
Evidence Code: 
IMP