Rv1985c HTH-type transcriptional regulator

Rv1985c (HTH-type transcriptional regulator) is predicted to be co-regulated in modules bicluster_0007 with residual 0.55 and bicluster_0380 with residual 0.52.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0007 and 0.07 and 0.10 for bicluster_0380 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 101 - 110 of 147
Gene Target Differential Expression Distance Expression pvalue Type
Transcriptional regulator, AsnC family
No 59 -0.26 0.538269 Internal.TSS
Transcriptional regulator, AsnC family
No 17 -0.26 0.538269 CDS
Alanine dehydrogenase (EC 1.4.1.1)
No -28 -0.03 0.954975 Primary.TSS
No -77 0.01 0.979652 Primary.TSS
CRISPR-associated protein Cas2
No -92 0.34 0.607512 Internal.TSS
No 35 0.09 0.834859 Primary.TSS
Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129)
Repressed 35 -0.7 0.0144298 CDS
(MTCY24G1.02), len: 496 aa, Probable polyketide synthase, almost identical to G560508 PKS002B (495 aa), fasta scores, opt: 3270, E(): 0, (99.6% identity in 496 aa overlap); contains PS00606 Beta-ketoacyl synthases active site; similar to MTCY338.20 (49.9% identity in 465 aa overlap) and MTCY24G1.09 (50.2% identity in 454 aa overlap) and MTCY22H8.03 (47.6% identity in 437 aa overlap)
No -25 -0.05 0.904253 CDS
ESAT-6-like protein EsxQ
No 39 -0.2 0.637318 CDS
10 kDa antigen CFP7
No -2 -0.38 0.664239 CDS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 8.34 U
D3I 3 3 3.83 7.89 I
D3U 3 3 3.83 8.32 U
D5I 9 5 6.00 10.84 I
D5U 17 5 6.00 11.33 U
D7I 18 7 8.14 6.54 I
D7U 19 7 8.14 7.53 U
D14I 4 14 15.63 3.27 I
D14U 4 14 15.63 6.73 U
D17I 3 17 19.15 I
D17U 3 17 19.15 5.97 U
D21I 4 21 23.23 2.50 I
D21U 4 21 23.23 6.26 U
D24I 3 24 26.60 I
D24U 3 24 26.60 5.95 U
D28I 4 28 30.61 I
D28U 4 28 30.61 5.77 U