Rv3765c putative two-component system response regulator

Rv3765c (putative two-component system response regulator) is predicted to be co-regulated in modules bicluster_0352 with residual 0.50 and bicluster_0526 with residual 0.56.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.01 and 2,900.00 for bicluster_0352 and 450.00 and 8,100.00 for bicluster_0526 respectively.

These modules are enriched for following go terms: cellular biosynthetic process, organic substance biosynthetic process, translational elongation, macromolecule metabolic process, biosynthetic process, intracellular, macromolecular complex, translation elongation factor activity RNA binding.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 21 - 30 of 49
Gene Target Differential Expression Distance Expression pvalue Type
No -100 -0.26 0.752689 CDS
PE family protein
No -31 -0.34 0.174511 Primary.TSS
Chalcone synthase (EC 2.3.1.74)
No -49 -0.05 0.907502 Primary.TSS
ESAT-6-like protein EsxL
No 9 0.39 0.490471 Primary.TSS
No -42 0.31 0.623743 Primary.TSS
Transcriptional repressor Mce3R, TetR family
No 38 -0.58 0.181669 Primary.TSS
HTH-type transcriptional regulator
No 62 -0.3 0.48492 CDS
Transporter, LysE family
Induced -24 1.17 0.00111204 Primary.TSS
No -102 -0.59 0.144572 CDS
Low molecular weight antigen MTB12 precursor
No 26 -0.49 0.0215989 Primary.TSS
not assigned to any KEGG Pathway.
GO:0008150

biological_process

biological_process

Details: 
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO Category: 
biological_process
66
Total items in this category:  
GO:0008150

biological_process

biological_process

Details: 
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO Category: 
biological_process
66
Total items in this category:  
GO:0010106

cellular response to iron ion starvation

cellular response to iron ion starvation

Details: 
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
GO Category: 
biological_process
14
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 13.83 U
D3I 3 3 3.83 13.94 I
D3U 3 3 3.83 13.91 U
D5I 9 5 6.00 9.27 I
D5U 17 5 6.00 12.09 U
D7I 18 7 8.14 9.96 I
D7U 19 7 8.14 13.67 U
D14I 4 14 15.63 4.75 I
D14U 4 14 15.63 11.47 U
D17I 3 17 19.15 3.15 I
D17U 3 17 19.15 10.90 U
D21I 4 21 23.23 3.00 I
D21U 4 21 23.23 9.45 U
D24I 3 24 26.60 I
D24U 3 24 26.60 9.26 U
D28I 4 28 30.61 1.73 I
D28U 4 28 30.61 7.66 U