Module Functions 1 "Energy production and conversion:Predicted sugar kinase:Molybdopterin biosynthesis enzyme:Transcriptional regulator:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Predicted transcriptional regulators:MoxR-like ATPases:Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Precorrin-6x reductase:FOG: GGDEF domain:Zn-dependent carboxypeptidase:Uncharacterized conserved protein:Plastocyanin:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Ca2+-binding protein (EF-Hand superfamily):Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Lysine biosynthesis:Nicotinate and nicotinamide metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:precor6x_red:pseudoazurin:Cytoskeleton:Poorly characterized:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Electron transport:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 2 "Predicted redox protein, regulator of disulfide bond formation:Predicted Zn-dependent peptidases:Membrane-associated phospholipid phosphatase:Uncharacterized membrane protein (homolog of Drosophila rhomboid):Exonuclease III:Deoxycytidine deaminase:ABC-type transport system involved in Fe-S cluster assembly, permease component:Predicted permeases:Cytochrome c biogenesis protein:Disulfide bond formation protein DsbB:Sulfite oxidase and related enzymes:Predicted membrane protein:Ribosomal protein L11 methylase:Secreted and surface protein containing fasciclin-like repeats:Predicted membrane protein:Uncharacterized conserved protein:Uncharacterized secreted protein:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pyrimidine metabolism:Metabolic pathways:Base excision repair:Sulfur relay system:General function prediction only:Function unknown:exoDNase_III:sufB:aProt_lowcomp:Biosynthesis of cofactors, prosthetic groups, and carriers:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Global:Replication and Repair:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Poorly characterized:Nucleotide Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Other" 3 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Molecular chaperone (small heat shock protein):Uncharacterized conserved protein:Acetolactate synthase, small (regulatory) subunit:ATP-dependent Lon protease, bacterial type:Signal transduction histidine kinase:Glutaredoxin and related proteins:Exonuclease III:Cation/multidrug efflux pump:Membrane-fusion protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Opacity protein and related surface antigens:ATP-dependent protease HslVU (ClpYQ), peptidase subunit:Uncharacterized small protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Valine leucine and isoleucine biosynthesis:Nitrotoluene degradation:Butanoate metabolism:C5-Branched dibasic acid metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:Base excision repair:Function unknown:Signal transduction mechanisms:TIGR00049:acolac_lg:acolac_sm:exoDNase_III:lon:RND_mfp:GRX_bact:sigma70-ECF:ATP_dep_HslV:Defense mechanisms:Energy metabolism:Metabolism:Metabolism:Global:Replication and Repair:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:DNA metabolism:Carbohydrate Metabolism:DNA replication, recombination, and repair:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Unknown substrate:Amino acid biosynthesis:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Electron transport" 4 "Leucyl aminopeptidase:Glycogen synthase:Aminopeptidase N:Selenocysteine lyase:Holliday junction resolvasome, DNA-binding subunit:Signal transduction histidine kinase:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Membrane-associated phospholipid phosphatase:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):ABC-type transport system involved in resistance to organic solvents, permease component:GTP cyclohydrolase II:Holliday junction resolvasome, endonuclease subunit:TRAP-type C4-dicarboxylate transport system, periplasmic component:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Predicted membrane protein:DNA polymerase III, chi subunit:Uncharacterized protein conserved in bacteria:TRAP-type mannitol/chloroaromatic compound transport system, small permease component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Purine metabolism:Pyrimidine metabolism:Glutathione metabolism:Starch and sucrose metabolism:Riboflavin metabolism:Metabolic pathways:DNA replication:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00056:ruvA:ruvC:sensory_box:ribA:glgA:pepN_proteo:Conserved:Carbohydrate Metabolism:Nucleotide Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Global:Metabolism:Energy metabolism:Biosynthesis and degradation of polysaccharides:Regulatory functions:Small molecule interactions:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Degradation of proteins, peptides, and glycopeptides:Hypothetical proteins:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Riboflavin, FMN, and FAD:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 5 "Sulfite reductase, beta subunit (hemoprotein):3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes:Predicted GTPase:Ribosomal protein S16:Membrane protease subunits, stomatin/prohibitin homologs:Leucyl-tRNA synthetase:Topoisomerase IA:UDP-N-acetylmuramate-alanine ligase:RimM protein, required for 16S rRNA processing:UDP-N-acetylmuramate dehydrogenase:Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis):Actin-like ATPase involved in cell division:ABC-type metal ion transport system, ATPase component:ABC-type spermidine/putrescine transport system, permease component II:ABC-type metal ion transport system, periplasmic component/surface antigen:Acetyltransferases, including N-acetylases of ribosomal proteins:ABC-type metal ion transport system, permease component:Membrane protein involved in the export of O-antigen and teichoic acid:Rhodanese-related sulfurtransferase:Uncharacterized protein conserved in bacteria:Alpha-N-acetylglucosamine transferase:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine biosynthesis:D-Glutamine and D-glutamate metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Sulfur metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Ribosome:Sulfur relay system:General function prediction only:Function unknown:S16:murB:RNAse_H_YqgF:TIGR00363:leuS_bact:cysH:topA_bact:murC:ftsA:16S_RimM:GTPase_YsxC:Metabolism:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Sulfur metabolism:DNA metabolism:DNA replication, recombination, and repair:Transcription:RNA processing:Protein synthesis:Other:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:Cellular processes:Cell division:Unknown function:General:Cell envelope:Other:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 6 "DNA polymerase III, alpha subunit:tRNA nucleotidyltransferase/poly(A) polymerase:S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Glycerophospholipid metabolism:RNA degradation:polc:DNA replication, recombination, and repair:Lipid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:DNA metabolism:Metabolism:Information storage and processing:Metabolism" 7 "Energy production and conversion:Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase):Putative translation initiation inhibitor, yjgF family:Lactoylglutathione lyase and related lyases:Molecular chaperone GrpE (heat shock protein):Transcriptional regulator:Glycerophosphoryl diester phosphodiesterase:ABC-type cobalt transport system, permease component CbiQ and related transporters:Cystathionine beta-lyases/cystathionine gamma-synthases:Predicted unusual protein kinase:Lipid A disaccharide synthetase:Nucleoside phosphorylase:DNA modification methylase:Nicotinic acid mononucleotide adenylyltransferase:Uncharacterized conserved protein:Trehalose-6-phosphatase:Protein-L-isoaspartate carboxylmethyltransferase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Gamma-glutamylcysteine synthetase:Uncharacterized conserved protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Cysteine and methionine metabolism:Selenocompound metabolism:Glutathione metabolism:Starch and sucrose metabolism:Lipopolysaccharide biosynthesis:Pyruvate metabolism:Nicotinate and nicotinamide metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:pimt:cyt_tran_rel:lpxB:T6PP:purK:glu_cys_lig_pln:AMP-nucleosdse:UbiB:CbiQ_TIGR:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Glutathione and analogs:Menaquinone and ubiquinone:Biosynthesis of cofactors, prosthetic groups, and carriers:Adaptations to atypical conditions:Cellular processes:Cations and iron carrying compounds:Transport and binding proteins:Protein modification and repair:Protein fate:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism" 8 "Energy production and conversion:Geranylgeranyl pyrophosphate synthase:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Phytoene dehydrogenase and related proteins:Nitrogenase subunit NifH (ATPase):Nitrogenase molybdenum-iron protein, alpha and beta chains:Amino acid transport and metabolism:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:beta-Alanine metabolism:Propanoate metabolism:Butanoate metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Carotenoid biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:bchC:phge_HK97_gp10:BchZ:BchY:BchX:crtI_fam:Photosynthesis:Mobile and extrachromosomal element functions:Prophage functions:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Chlorophyll and bacteriochlorphyll:Metabolism:Poorly characterized:Energy metabolism:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Carbohydrate Metabolism" 9 "" 10 "Energy production and conversion:Predicted sugar kinase:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:FAD/FMN-containing dehydrogenases:Selenocysteine lyase:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Glutathione S-transferase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:GTP cyclohydrolase II:Predicted glycosyltransferases:Uncharacterized protein conserved in bacteria:Transcriptional regulator of heat shock gene:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Predicted metal-dependent hydrolase with the TIM-barrel fold:Chromate transport protein ChrA:Precorrin-6x reductase:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Uncharacterized conserved protein:DNA polymerase III, gamma/tau subunits:Uncharacterized protein conserved in bacteria:Putative hemolysin:Ribonuclease I:Uncharacterized protein conserved in bacteria:L-asparaginase II:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glutathione metabolism:Pyruvate metabolism:Riboflavin metabolism:Nicotinate and nicotinamide metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Two-component system:RNA polymerase:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00046:hrcA:ribA:precor6x_red:2A51:TIGR02246:rpoN_sigma:PPK2_P_aer:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Riboflavin, FMN, and FAD:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Anions:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:Transcription factors:Transcription:DNA interactions:Regulatory functions:Phosphorus compounds:Central intermediary metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Replication and Repair:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Nucleotide Metabolism:Carbohydrate Metabolism" 11 "Nucleotidyltransferase/DNA polymerase involved in DNA repair:Transcriptional regulator:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):2-hydroxychromene-2-carboxylate isomerase:Predicted alpha/beta hydrolase:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Fructose and mannose metabolism:Bisphenol degradation:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Metabolism:Carbohydrate Metabolism:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Information storage and processing:Metabolism:Poorly characterized" 12 "Molybdopterin-guanine dinucleotide biosynthesis protein A:Cation/multidrug efflux pump:Membrane-fusion protein:Predicted branched-chain amino acid permease (azaleucine resistance):Transcriptional regulator:Molybdopterin-guanine dinucleotide biosynthesis protein:Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis:Arabinose efflux permease:Outer membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Secondary metabolites biosynthesis, transport and catabolism:mobB:RND_mfp:molyb_mobA:Defense mechanisms:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Unknown substrate:Transport and binding proteins:Cellular processes and signaling:Metabolism" 13 "Acetyltransferase (isoleucine patch superfamily):Na+-driven multidrug efflux pump:DnaJ-domain-containing proteins 1:Transcriptional regulator, effector-binding domain/component:Transcription:Posttranslational modification, protein turnover, chaperones:General function prediction only:Signal transduction mechanisms:matE:Defense mechanisms:Poorly characterized:Cellular processes and signaling:Information storage and processing:Other:Transport and binding proteins" 14 "Energy production and conversion:Glycosyltransferase:Superfamily II DNA and RNA helicases:Signal transduction histidine kinase:Transcription elongation factor:ATPase components of various ABC-type transport systems, contain duplicated ATPase:Methylmalonyl-CoA mutase, N-terminal domain/subunit:Predicted esterase of the alpha/beta hydrolase fold:Predicted lactoylglutathione lyase:Cytochrome b:Phage head maturation protease:Phage terminase-like protein, large subunit:Phage-related protein:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glyoxylate and dicarboxylate metabolism:Microbial metabolism in diverse environments:ABC transporters:Ribosome:General function prediction only:Function unknown:Signal transduction mechanisms:recQ_fam:acid_CoA_mut_C:portal_HK97:proheadase_HK97:Metabolism:Carbohydrate Metabolism:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Other:Mobile and extrachromosomal element functions:Prophage functions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 15 "Energy production and conversion:Glutamyl- and glutaminyl-tRNA synthetases:Uracil phosphoribosyltransferase:F0F1-type ATP synthase, beta subunit:Isoleucyl-tRNA synthetase:Nucleoside diphosphate kinase:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Tyrosyl-tRNA synthetase:Thymidine phosphorylase:F0F1-type ATP synthase, gamma subunit:Malic enzyme:Cytidine deaminase:F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit):F0F1-type ATP synthase, subunit a:ATPase components of ABC transporters with duplicated ATPase domains:F0F1-type ATP synthase, subunit b:Phosphopentomutase:NAD/NADP transhydrogenase beta subunit:Adenosine deaminase:Multiple antibiotic transporter:NAD/NADP transhydrogenase alpha subunit:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Pentose phosphate pathway:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Carbon fixation in photosynthetic organisms:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:ilvD:tyrS:ileS:TIGR00427:gltX_bact:pntA:atpD:upp:ATP_synt_6_or_A:ATPsyn_F1gamma:ATP_synt_epsi:cyt_deam_tetra:aden_deam:deoB:Y_phosphoryl:Intracellular trafficking, secretion, and vesicular transport:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:Electron transport:Purines, pyrimidines, nucleosides, and nucleotides:Other:Salvage of nucleosides and nucleotides:Protein synthesis:tRNA aminoacylation:Unknown function:General:Amino acid biosynthesis:Pyruvate family:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 16 "Energy production and conversion:4-aminobutyrate aminotransferase and related aminotransferases:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Glutamine synthetase:ABC-type Co2+ transport system, permease component:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:ADP-glucose pyrophosphorylase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted esterase:Signal transduction histidine kinase:Predicted permeases:Urease accessory protein UreH:Urea amidohydrolase (urease) gamma subunit:Urea amidohydrolase (urease) beta subunit:NAD-dependent aldehyde dehydrogenases:Pyruvate carboxylase:Alcohol dehydrogenase, class IV:Uncharacterized protein conserved in bacteria:Transcriptional regulators:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Putative homoserine kinase type II (protein kinase fold):Predicted ornithine cyclodeaminase, mu-crystallin homolog:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Uncharacterized protein involved in cysteine biosynthesis:Predicted N-formylglutamate amidohydrolase:TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component:TRAP-type mannitol/chloroaromatic compound transport system, large permease component:TRAP-type mannitol/chloroaromatic compound transport system, small permease component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Fructose and mannose metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Geraniol degradation:Arginine and proline metabolism:Bisphenol degradation:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Polycyclic aromatic hydrocarbon degradation:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Butanoate metabolism:Methane metabolism:Atrazine degradation:Limonene and pinene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:urease_beta:urease_gam:pyruv_carbox:glgC:fghA_ester_D:Glycolysis/gluconeogenesis:Energy metabolism:Nitrogen metabolism:Central intermediary metabolism:Detoxification:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism:Global:Metabolism:Signal Transduction:Poorly characterized:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Cellular processes:Carbohydrate Metabolism:Biosynthesis and degradation of polysaccharides" 17 "Histidinol dehydrogenase:Biotin-(acetyl-CoA carboxylase) ligase:ABC-type branched-chain amino acid transport systems, ATPase component:ABC-type branched-chain amino acid transport systems, ATPase component:Predicted choline kinase involved in LPS biosynthesis:Branched-chain amino acid ABC-type transport system, permease components:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:ABC-type branched-chain amino acid transport systems, periplasmic component:ABC-type dipeptide transport system, periplasmic component:ATPase components of various ABC-type transport systems, contain duplicated ATPase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Uncharacterized protein conserved in bacteria:TRAP-type C4-dicarboxylate transport system, periplasmic component:Choline dehydrogenase and related flavoproteins:TRAP-type C4-dicarboxylate transport system, small permease component:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type branched-chain amino acid transport system, permease component:TRAP-type mannitol/chloroaromatic compound transport system, large permease component:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pyrimidine metabolism:Histidine metabolism:beta-Alanine metabolism:Phosphonate and phosphinate metabolism:Pantothenate and CoA biosynthesis:Biotin metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:hisD:birA_ligase:sensory_box:GGDEF:dctM:hydantase:Signal transduction:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Environmental Information Processing:Membrane Transport:Global:Metabolism:Regulatory functions:Small molecule interactions:Protein fate:Protein modification and repair:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Amino acid biosynthesis:Histidine family:Metabolism:Other:Cellular processes and signaling:Metabolism:Poorly characterized" 18 "Energy production and conversion:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Phytoene dehydrogenase and related proteins:Nitrogenase subunit NifH (ATPase):Cobalamin biosynthesis protein CobN and related Mg-chelatases:Phytoene/squalene synthetase:Nitrogenase molybdenum-iron protein, alpha and beta chains:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:Carotenoid biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:puhA:bchC:DPOR_BchB:DPOR_bchN:DPOR_bchL:BchZ:BchY:BchF:crtI_fam:photo_alph_chp1:Energy metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Global:Metabolism:Metabolism:Photosynthesis:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Chlorophyll and bacteriochlorphyll:Metabolism:Poorly characterized" 19 "Energy production and conversion:Transcriptional regulator:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Signal transduction histidine kinase:Heme/copper-type cytochrome/quinol oxidases, subunit 1:ATPase components of various ABC-type transport systems, contain duplicated ATPase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type Na+ efflux pump, permease component:Permeases of the major facilitator superfamily:Transposase and inactivated derivatives:Arabinose efflux permease:Predicted lactoylglutathione lyase:Uncharacterized stress protein (general stress protein 26):Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Predicted integral membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Oxidative phosphorylation:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:efflux_Bcr_CflA:CtaD_CoxA:Metabolism:Cellular processes and signaling:Information storage and processing:Electron transport:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Metabolism:Energy Metabolism:Poorly characterized" 20 "Predicted glutamine amidotransferase:DNA repair exonuclease:Single-stranded DNA-specific exonuclease:Glutathione S-transferase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Uncharacterized protein conserved in bacteria:Pterin-4a-carbinolamine dehydratase:Methylase involved in ubiquinone/menaquinone biosynthesis:Citrate lyase beta subunit:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Signal transduction histidine kinase:Uncharacterized protein conserved in bacteria:Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase):Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glutathione metabolism:Glyoxylate and dicarboxylate metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Base excision repair:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:recJ:CobT:tol_pal_ybgF:Pal_lipo:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Carbohydrate Metabolism" 21 "Energy production and conversion:Predicted PP-loop superfamily ATPase:Rieske Fe-S protein:Cytochrome b subunit of the bc complex:Cytochrome c1:Cytochrome c2:Predicted ATP-dependent endonuclease of the OLD family:Nucleoside 2-deoxyribosyltransferase:Cytochrome c556:Sarcosine oxidase delta subunit:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Replication, recombination and repair:Oxidative phosphorylation:Glycine serine and threonine metabolism:Metabolic pathways:Nucleotide excision repair:Mismatch repair:General function prediction only:Function unknown:TAT_signal_seq:Poorly characterized:Energy Metabolism:Amino Acid Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:Protein fate:Protein and peptide secretion and trafficking:Information storage and processing:Metabolism:Metabolism" 22 "NhaP-type Na+/H+ and K+/H+ antiporters:Predicted Co/Zn/Cd cation transporters:Geranylgeranyl pyrophosphate synthase:7-keto-8-aminopelargonate synthetase and related enzymes:FOG: CheY-like receiver:Membrane-fusion protein:ABC-type antimicrobial peptide transport system, ATPase component:Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism:Predicted signal-transduction protein containing cAMP-binding and CBS domains:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Phosphonate and phosphinate metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:DNA replication:Mismatch repair:Homologous recombination:Signal transduction mechanisms:dnaq:phnA:CDF:RND_mfp:5aminolev_synth:Defense mechanisms:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Cellular processes and signaling:Metabolism:Unknown substrate:Transport and binding proteins:Degradation of DNA:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Cations and iron carrying compounds:Nucleotide Metabolism" 23 "Energy production and conversion:Glutaredoxin-related protein:Predicted membrane protein:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Putative GTPases (G3E family):Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Glutathione S-transferase:Predicted phosphatase/phosphohexomutase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type cobalt transport system, ATPase component:Flagellar biosynthesis pathway, component FlhB:Predicted acyl-CoA transferases/carnitine dehydratase:Galactose mutarotase and related enzymes:Glucose/sorbosone dehydrogenases:Lysophospholipase:Uncharacterized protein conserved in bacteria:Predicted phosphotransferase related to Ser/Thr protein kinases:Uncharacterized protein conserved in bacteria:Arginine degradation protein (predicted deacylase):Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Fructose and mannose metabolism:Benzoate degradation:Bisphenol degradation:Glycerolipid metabolism:Glycerophospholipid metabolism:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Flagellar assembly:RNA degradation:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00023:GGDEF:TIGR00365:HAD-SF-IA-v3:phge_HK97_gp10:protocat_pcaD:Intracellular trafficking, secretion, and vesicular transport:Fatty acid and phospholipid metabolism:Other:Electron transport:Energy metabolism:Metabolism:Global:Metabolism:Cell Motility:Cellular Processes:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Lipid Metabolism:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Other:Signal transduction:Enzymes of unknown specificity:Unknown function:Prophage functions:Mobile and extrachromosomal element functions:Biosynthesis" 24 "Glucose-6-phosphate isomerase:6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase:Glucose-6-phosphate 1-dehydrogenase:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Periplasmic protein TonB, links inner and outer membranes:Biopolymer transport proteins:Biopolymer transport protein:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:ABC-type multidrug transport system, ATPase and permease components:Predicted membrane protein, hemolysin III homolog:D-mannonate dehydratase:Outer membrane receptor proteins, mostly Fe transport:Siderophore-interacting protein:Uncharacterized iron-regulated protein:5-keto 4-deoxyuronate isomerase:ABC-type enterochelin transport system, ATPase component:ABC-type enterochelin transport system, permease component:ABC-type enterochelin transport system, permease component:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Glutathione metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Ribosome:General function prediction only:uxuA:zwf:pgl:tonB_Cterm:TonB-siderophor:exbB:ExbD_1:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Porins:Cations and iron carrying compounds:Transport and binding proteins:Sugars:Pentose phosphate pathway:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Metabolism of Other Amino Acids:Metabolism:Carbohydrate Metabolism" 25 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Uracil phosphoribosyltransferase:Malate/lactate dehydrogenases:Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog):Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Glutamine synthetase:Acetyl-CoA acetyltransferase:Thymidine phosphorylase:NAD-dependent DNA ligase (contains BRCT domain type II):Malic enzyme:Lactoylglutathione lyase and related lyases:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Aspartate carbamoyltransferase, catalytic chain:DNA polymerase sliding clamp subunit (PCNA homolog):ATPase involved in DNA replication initiation:Peroxiredoxin:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:Ribonucleases G and E:Predicted periplasmic solute-binding protein:D-alanyl-D-alanine carboxypeptidase:Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit:Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit:Tetrahydrodipicolinate N-succinyltransferase:TRAP-type uncharacterized transport system, periplasmic component:TRAP-type uncharacterized transport system, fused permease components:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Fatty acid metabolism:Synthesis and degradation of ketone bodies:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Lysine biosynthesis:Lysine degradation:Arginine and proline metabolism:Benzoate degradation:Tryptophan metabolism:Taurine and hypotaurine metabolism:Peptidoglycan biosynthesis:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Carbon fixation in photosynthetic organisms:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA degradation:DNA replication:Base excision repair:Nucleotide excision repair:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:gatB:TIGR00247:DnaA:dnlj:GlnA:dnan:asp_carb_tr:RNaseEG:dapD:upp:PDHac_trf_mito:MalateDH_bact:AcAcCoA_reduct:AcCoA-C-Actrans:TRAP_TAXI:TRAP_fused:pcaJ_scoB_fam:pcaI_scoA_fam:Y_phosphoryl:PDH_E1_alph_y:Carbohydrate Metabolism:Metabolism:Energy metabolism:Pyruvate dehydrogenase:TCA cycle:Fatty acid and phospholipid metabolism:Other:Purines, pyrimidines, nucleosides, and nucleotides:Other:Pyrimidine ribonucleotide biosynthesis:Salvage of nucleosides and nucleotides:DNA metabolism:DNA replication, recombination, and repair:Transcription:Degradation of RNA:Protein synthesis:tRNA aminoacylation:Transport and binding proteins:Unknown substrate:Hypothetical proteins:Conserved:Amino acid biosynthesis:Aspartate family:Glutamate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Signal Transduction:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Global" 26 "Energy production and conversion:Signal transduction histidine kinase:Shikimate kinase:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type multidrug transport system, ATPase component:Transcriptional regulator:ABC-type sugar transport system, periplasmic component:ABC-type polysaccharide/polyol phosphate export systems, permease component:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized conserved protein:Cytochrome c2:Glucose dehydrogenase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Phenylalanine tyrosine and tryptophan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Function unknown:Signal transduction mechanisms:beta_rpt_yvtn:PQQ_enz_alc_DH:phenyl_ABC_PedC:PQQ_ABC_bind:PQQ_ABC_ATP:PQQ_CXXCW:ABC_peri_MoxJ_2:4cys_cytochr:Defense mechanisms:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism" 27 "Energy production and conversion:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Polyferredoxin:Trehalose-6-phosphate synthase:Integrase:Glycine/D-amino acid oxidases (deaminating):ATPase components of various ABC-type transport systems, contain duplicated ATPase:Methylase involved in ubiquinone/menaquinone biosynthesis:TRAP-type uncharacterized transport system, periplasmic component:DNA-binding HTH domain-containing proteins:Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains:Cytochrome b:Uncharacterized copper-binding protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Starch and sucrose metabolism:One carbon pool by folate:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:General function prediction only:Signal transduction mechanisms:nifA:TRAP_TAXI:trehalose_OtsA:Information storage and processing:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Global:Metabolism:Regulatory functions:DNA interactions:Transport and binding proteins:Unknown substrate:Cellular processes:Adaptations to atypical conditions:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 28 "Sugar phosphate permease:Carbohydrate transport and metabolism:Metabolism" 29 "Trk-type K+ transport systems, membrane components:Permeases of the drug/metabolite transporter (DMT) superfamily:FOG: CheY-like receiver:Predicted transcriptional regulators:Flagellar hook protein FlgE:GAF domain-containing protein:3-methyladenine DNA glycosylase:Anti-sigma regulatory factor (Ser/Thr protein kinase):Uncharacterized conserved protein:Uncharacterized conserved protein:Bacteriophage capsid protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Flagellar assembly:Base excision repair:General function prediction only:Function unknown:Signal transduction mechanisms:3mg:portal_lambda:cas3_core:primase_Cterm:chp_TIGR02217:FlgEFG_subfam:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Prophage functions:Mobile and extrachromosomal element functions:DNA replication, recombination, and repair:DNA metabolism:Genetic Information Processing:Cell Motility:Cellular Processes:Poorly characterized:Replication and Repair" 30 "Gamma-glutamyl phosphate reductase:3-isopropylmalate dehydratase large subunit:Cysteinyl-tRNA synthetase:Glutamate 5-kinase:Molybdopterin biosynthesis enzyme:Molybdenum cofactor biosynthesis enzyme:RecA/RadA recombinase:Predicted GTPase:Alanine racemase:Lhr-like helicases:Predicted ICC-like phosphoesterases:Uncharacterized protein conserved in bacteria:SOS-response transcriptional repressors (RecA-mediated autopeptidases):Galactose mutarotase and related enzymes:Sulfite oxidase and related enzymes:Arabinose efflux permease:Thioredoxin domain-containing protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:D-Alanine metabolism:C5-Branched dibasic acid metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Homologous recombination:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:leuC:proA:cysS:alr:lexA:moaC:proB:thioredoxin:tigrfam_recA:Obg_CgtA:Cellular processes and signaling:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Translation:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Energy metabolism:Electron transport:Regulatory functions:DNA interactions:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Other:tRNA aminoacylation:Amino acid biosynthesis:Glutamate family:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 31 "Energy production and conversion:Nucleoside-diphosphate-sugar epimerases:Predicted choline kinase involved in LPS biosynthesis:Chemotaxis protein histidine kinase and related kinases:FOG: CheY-like receiver:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:NAD-dependent aldehyde dehydrogenases:ABC-type spermidine/putrescine transport system, permease component II:Methylase of chemotaxis methyl-accepting proteins:Flagellar motor protein:Flagellar basal-body P-ring protein:Predicted metal-dependent hydrolase with the TIM-barrel fold:Chemotaxis protein; stimulates methylation of MCP proteins:ABC-type thiamine transport system, ATPase component:ABC-type spermidine/putrescine transport systems, ATPase components:Uncharacterized membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Function unknown:Signal transduction mechanisms:Metabolism:Global:Metabolism:Cellular processes and signaling:Cell Motility:Cellular Processes:Metabolism:Signal Transduction:Poorly characterized:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides" 32 "Energy production and conversion:Mannitol-1-phosphate/altronate dehydrogenases:ABC-type sulfate transport system, permease component:Methionine synthase I (cobalamin-dependent), methyltransferase domain:Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit:Multisubunit Na+/H+ antiporter, MnhC subunit:NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Multisubunit Na+/H+ antiporter, MnhG subunit:Methionine synthase I, cobalamin-binding domain:TRAP-type C4-dicarboxylate transport system, large permease component:TRAP-type C4-dicarboxylate transport system, periplasmic component:Multisubunit Na+/H+ antiporter, MnhE subunit:Transcriptional regulators:Multisubunit Na+/H+ antiporter, MnhF subunit:Altronate dehydratase:TRAP-type C4-dicarboxylate transport system, small permease component:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type sulfate transport system, periplasmic component:ABC-type sulfate transport system, permease component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Cysteine and methionine metabolism:One carbon pool by folate:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:dctM:3a0106s01:3a0106s02:3a0106s03:CPA3_mnhG_phaG:metH:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transport and binding proteins:Anions:Carbohydrates, organic alcohols, and acids:Cations and iron carrying compounds:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 33 "3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase:Cobalamin-5-phosphate synthase:Predicted esterase:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:Signal transduction histidine kinase:Predicted UDP-glucose 6-dehydrogenase:NaMN:DMB phosphoribosyltransferase:Predicted permease, DMT superfamily:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Riboflavin metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Base excision repair:General function prediction only:Signal transduction mechanisms:cobS:NDP-sugDHase:cobT_DBIPRT:Metabolism:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Replication and Repair:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 34 "Energy production and conversion:Transketolase:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Fructose-1,6-bisphosphatase:Fructose/tagatose bisphosphate aldolase:Ribulose 1,5-bisphosphate carboxylase, large subunit:Phosphoribulokinase:ABC-type Co2+ transport system, periplasmic component:Carbohydrate transport and metabolism:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Carbon fixation in photosynthetic organisms:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:cbbA:tktlase_bact:GAPDH-I:phge_HK97_gp10:Mobile and extrachromosomal element functions:Prophage functions:Metabolism:Energy metabolism:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Energy Metabolism:Glycolysis/gluconeogenesis:Carbohydrate Metabolism:Pentose phosphate pathway" 35 "Energy production and conversion:Molybdopterin biosynthesis enzymes:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Thioredoxin-like proteins and domains:Zn-dependent alcohol dehydrogenases, class III:Putative threonine efflux protein:Uncharacterized protein conserved in bacteria:Recombinational DNA repair protein (RecF pathway):Predicted lactoylglutathione lyase:Ribonuclease I:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Predicted mannose-6-phosphate isomerase:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Usg protein, probable subunit of phosphoribosylanthranilate isomerase:Uncharacterized conserved small protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Arginine and proline metabolism:Tyrosine metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Homologous recombination:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:molyb_syn:reco:pro_imino_pep_1:Phn_opern_protn:Folding Sorting and Degradation:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Lipid Metabolism:DNA metabolism:Carbohydrate Metabolism:DNA replication, recombination, and repair:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Replication and Repair" 36 "Energy production and conversion:Malic enzyme:tRNA delta(2)-isopentenylpyrophosphate transferase:Protein-tyrosine-phosphatase:Kef-type K+ transport systems, membrane components:Superfamily II DNA and RNA helicases:Sugar kinases, ribokinase family:1-deoxy-D-xylulose 5-phosphate reductoisomerase:ABC-type dipeptide transport system, periplasmic component:Predicted membrane-associated Zn-dependent proteases 1:NADH dehydrogenase, FAD-containing subunit:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Phosphoenolpyruvate carboxykinase (ATP):Uncharacterized enzyme involved in pigment biosynthesis:TRAP-type uncharacterized transport system, periplasmic component:DNA polymerase III, gamma/tau subunits:Uncharacterized conserved protein:Signal transduction histidine kinase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Pentose phosphate pathway:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Pyruvate metabolism:Carbon fixation in photosynthetic organisms:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:RNA polymerase:DNA replication:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00054:miaA:pckA:Dxr:recQ_fam:TRAP_TAXI:rpoN_sigma:Poorly characterized:Transcription factors:Transcription:DNA replication, recombination, and repair:DNA metabolism:Glycolysis/gluconeogenesis:Energy metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism:Replication and Repair:Transcription:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Nucleotide Metabolism:Energy Metabolism:Protein synthesis:Carbohydrate Metabolism:tRNA and rRNA base modification:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Unknown substrate:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism" 37 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Acetyl-CoA acetyltransferase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Zn-dependent hydrolases, including glyoxylases:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted acyl-CoA transferases/carnitine dehydratase:Acyl-CoA dehydrogenases:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Dioxygenases related to 2-nitropropane dioxygenase:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component:Acetyl/propionyl-CoA carboxylase, alpha subunit:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Amino acid transport and metabolism:Lipid transport and metabolism:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:unchar_dom_1:HIBADH:AcCoA-C-Actrans:Metabolism:Global:Fatty acid and phospholipid metabolism:Amino acids and amines:Energy metabolism:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Other" 38 "Energy production and conversion:Anaerobic dehydrogenases, typically selenocysteine-containing:Heme/copper-type cytochrome/quinol oxidases, subunit 1:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):UDP-glucose 4-epimerase:dTDP-D-glucose 4,6-dehydratase:Putative threonine efflux protein:Transglutaminase-like enzymes, putative cysteine proteases:Uracil-DNA glycosylase:Transcriptional regulators:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:Uncharacterized protein conserved in bacteria:Predicted acyl esterases:Uncharacterized conserved protein:Predicted esterase of the alpha/beta hydrolase fold:Uncharacterized conserved protein:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Predicted periplasmic protein:Delta 1-pyrroline-5-carboxylate dehydrogenase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Galactose metabolism:Oxidative phosphorylation:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Amino sugar and nucleotide sugar metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:/NonD:D1pyr5carbox3:Fdhalpha-like:tape_meas_nterm:formald_GSH:CtaD_CoxA:UDG_fam_dom:Metabolism:Metabolism:Global:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Electron transport:Amino acids and amines:Energy metabolism:One-carbon metabolism:Central intermediary metabolism" 39 "tRNA and rRNA cytosine-C5-methylases:Predicted acid phosphatase:Uncharacterized membrane-associated protein:Cytosine/adenosine deaminases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted ATP-dependent serine protease:Transcriptional regulators of sugar metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:surE:sms:Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Cellular processes:Adaptations to atypical conditions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 40 "1,4-alpha-glucan branching enzyme:Glycosidases:FOG: CheY-like receiver:Na+/phosphate symporter:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Type II secretory pathway, pullulanase PulA and related glycosidases:4-alpha-glucanotransferase:Maltooligosyl trehalose synthase:Phage protein U:Uncharacterized protein conserved in bacteria:Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain:Carbohydrate transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Starch and sucrose metabolism:Metabolic pathways:Two-component system:Bacterial chemotaxis:General function prediction only:Function unknown:Signal transduction mechanisms:malQ:branching_enzym:glgX_debranch:trehalose_TreY:trehalose_TreZ:treS_nterm:Cellular processes and signaling:Carbohydrate Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:Biosynthesis and degradation of polysaccharides:Metabolism:Metabolism:Poorly characterized" 41 "Uroporphyrinogen-III methylase:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:7-keto-8-aminopelargonate synthetase and related enzymes:Putative GTPases (G3E family):ABC-type Fe3+-hydroxamate transport system, periplasmic component:Precorrin-3B methylase:Cobyrinic acid a,c-diamide synthase:Precorrin-6B methylase 1:Precorrin-2 methylase:Precorrin-4 methylase:Signal transduction histidine kinase, nitrogen specific:Outer membrane cobalamin receptor protein:Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase:Predicted metal-binding protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:cobB:L_thr_O3P_dcar:cobM_cbiF:cobJ_cbiH:cobI_cbiL:cobA_cysG_Cterm:5aminolev_synth:CobF:CbiE:CobW:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Poorly characterized:Amino Acid Metabolism:Metabolism:Cellular processes and signaling" 42 "Uncharacterized conserved protein:Na+-driven multidrug efflux pump:rRNA methylases:ABC-type antimicrobial peptide transport system, permease component:ABC-type antimicrobial peptide transport system, ATPase component:Predicted membrane protein:Inactivated superfamily I helicase:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Function unknown:rRNA_methyl_3:matE:addB_alphas:Defense mechanisms:Other:Transport and binding proteins:Poorly characterized:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:tRNA and rRNA base modification:Cellular processes and signaling:Information storage and processing" 43 "Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:S-adenosylmethionine synthetase:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Biotin carboxyl carrier protein:Superfamily II DNA and RNA helicases:Preprotein translocase subunit SecA (ATPase, RNA helicase):Preprotein translocase subunit YidC:Membrane carboxypeptidase (penicillin-binding protein):7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase:Transcription termination factor:Transcriptional regulators, similar to M. xanthus CarD:Uncharacterized conserved protein:Ribosome-associated protein Y (PSrp-1):Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems:Leu/Phe-tRNA-protein transferase:Predicted hydrolase of the alpha/beta superfamily:Cell wall hydrolyses involved in spore germination:Predicted membrane protein:Acetyl/propionyl-CoA carboxylase, alpha subunit:Outer membrane protein/protective antigen OMA87:Membrane-bound metallopeptidase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved small protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid biosynthesis:Purine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Selenocompound metabolism:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Folate biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:RNA degradation:Protein export:Bacterial secretion system:General function prediction only:Function unknown:accC:BCCP:aat:yfiA:rho:secA:metK:gyrA:folK:PBP_1a_fam:OM_YaeT:yidC_oxa1_cterm:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Other:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:Transcription factors:Protein synthesis:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Degradation of proteins, peptides, and glycopeptides:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 44 "Energy production and conversion:Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit:Esterase/lipase:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:Sugar (pentulose and hexulose) kinases:ABC-type sugar transport system, ATPase component:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain:ABC-type sugar transport system, periplasmic component:Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain:Transcriptional regulators:Sugar phosphate permease:Transcriptional regulator, contains sigma factor-related N-terminal domain:Predicted membrane protein:Histidine ammonia-lyase:Predicted membrane protein:ABC-type sugar transport systems, ATPase components:ABC-type spermidine/putrescine transport systems, ATPase components:Hydantoin racemase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Citrate cycle (TCA cycle):Oxidative phosphorylation:Bisphenol degradation:Toluene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Function unknown:dhsB:ttdA_fumA_fumB:succ_dehyd_cytB:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Energy Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Information storage and processing:TCA cycle:Energy metabolism:Metabolism" 45 "Energy production and conversion:Purine nucleoside phosphorylase:7-keto-8-aminopelargonate synthetase and related enzymes:Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family:Nucleoside-diphosphate-sugar epimerases:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Deoxyxylulose-5-phosphate synthase:Mg-chelatase subunit ChlI:Mg-chelatase subunit ChlD:Cytochrome B561:Cytochrome c2:Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog):Uncharacterized conserved protein:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Purine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Function unknown:Signal transduction mechanisms:dxs:salvage_mtnA:apt:MTAP:5aminolev_synth:BchI-ChlI:BchD-ChlD:Thiamine:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:Amino acid biosynthesis:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Metabolism:Chlorophyll and bacteriochlorphyll:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 46 "Energy production and conversion:Acyl carrier protein:Adenylate kinase and related kinases:Transcriptional regulator:Signal transduction histidine kinase:Thioredoxin-like proteins and domains:UDP-3-O-acyl-N-acetylglucosamine deacetylase:NifU homolog involved in Fe-S cluster formation:Ribosome-binding factor A:Serine acetyltransferase:Uncharacterized conserved protein:Predicted glutamine amidotransferases:DNA-binding HTH domain-containing proteins:Outer membrane lipoprotein-sorting protein:Putative arginyl-tRNA:protein arginylyltransferase:Uncharacterized protein involved in tellurite resistance:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Lipopolysaccharide biosynthesis:Sulfur metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:rbfA:lpxC:cysE:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Serine family:Amino acid biosynthesis:RNA processing:Transcription:Metabolism:Global:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Metabolism:Energy Metabolism:Poorly characterized:Metabolism" 47 "Methionyl-tRNA formyltransferase:Ribosomal protein S16:N-formylmethionyl-tRNA deformylase:Nucleoside-diphosphate-sugar epimerases:Adenylate kinase and related kinases:Cell division protein FtsI/penicillin-binding protein 2:Bacterial cell division membrane protein:FOG: CheY-like receiver:RimM protein, required for 16S rRNA processing:ABC-type (unclassified) transport system, ATPase component:ABC-type spermidine/putrescine transport system, permease component II:Chorismate mutase:Predicted hydrolases of HD superfamily:Sugar transferases involved in lipopolysaccharide synthesis:SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Protein involved in catabolism of external DNA:Uncharacterized protein conserved in bacteria:Alpha-N-acetylglucosamine transferase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Purine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Peptidoglycan biosynthesis:One carbon pool by folate:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Ribosome:General function prediction only:Function unknown:Signal transduction mechanisms:S16:pept_deformyl:fmt:adk:CM_mono_cladeE:rodA_shape:16S_RimM:pbp2_mrdA:Cell division:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Transcription:RNA processing:Protein synthesis:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:Protein fate:Protein modification and repair:Cellular processes:Metabolism:Amino acid biosynthesis:Aromatic amino acid family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 48 "Energy production and conversion:Acyl carrier protein:Single-stranded DNA-binding protein:Holliday junction resolvasome, DNA-binding subunit:Protease subunit of ATP-dependent Clp proteases:Bacterial nucleoid DNA-binding protein:Holliday junction resolvasome, endonuclease subunit:NifU homolog involved in Fe-S cluster formation:Acetyl-CoA carboxylase alpha subunit:ABC-type cobalt transport system, ATPase component:ATP-dependent protease Clp, ATPase subunit:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:DNA-binding protein H-NS:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved small protein:Uncharacterized conserved protein:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Ribosome:DNA replication:Protein export:Bacterial secretion system:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:S21p:ruvA:ruvC:clpX:accA:ssb:hip:tatAE:diverge_rpsU:Intracellular trafficking, secretion, and vesicular transport:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Metabolism:Translation:Genetic Information Processing:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:Ribosomal proteins: synthesis and modification:Protein fate:Protein and peptide secretion and trafficking:Degradation of proteins, peptides, and glycopeptides:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction" 49 "Energy production and conversion:Short-chain dehydrogenases of various substrate specificities:NADH dehydrogenase, FAD-containing subunit:Multidrug resistance efflux pump:Predicted acyltransferases:Cation transport ATPase:Uncharacterized protein conserved in bacteria:Cytochrome B561:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Inorganic ion transport and metabolism:Fatty acid metabolism:Oxidative phosphorylation:Metabolic pathways:Two-component system:General function prediction only:Function unknown:ATPase_P-type:Defense mechanisms:Poorly characterized:Energy Metabolism:Lipid Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Cellular processes and signaling:Metabolism:Metabolism" 50 "Indole-3-glycerol phosphate synthase:Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis:Amino acid transport and metabolism:Cell wall/membrane/envelope biogenesis:Phenylalanine tyrosine and tryptophan biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Protein export:TIGR00006:PQQ_syn_pqqA:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cellular processes and signaling:Metabolism:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism:Amino Acid Metabolism" 51 "Energy production and conversion:Glutamyl- and glutaminyl-tRNA synthetases:Phenylalanyl-tRNA synthetase beta subunit:Imidazoleglycerol-phosphate synthase:AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful):Tryptophan synthase alpha chain:Argininosuccinate lyase:5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase:3-oxoacyl-(acyl-carrier-protein) synthase:Ribonuclease D:Predicted esterase:Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains:Membrane GTPase LepA:Predicted phosphatases:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Parvulin-like peptidyl-prolyl isomerase:Periplasmic protease:N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains):Peroxiredoxin:N-acetylglutamate synthase (N-acetylornithine aminotransferase):Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fatty acid biosynthesis:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Histidine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Amino sugar and nucleotide sugar metabolism:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Carbon fixation pathways in prokaryotes:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:ArgJ:prc:small_GTP:trpA:purH:gltX_bact:pheT_bact:hisF:argH:glmS:glmU:rnd:Ubi-OHases:fabF:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Metabolism:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Central intermediary metabolism:Amino sugars:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Transcription:RNA processing:Protein synthesis:tRNA aminoacylation:Protein fate:Protein modification and repair:Unknown function:General:Amino acid biosynthesis:Aromatic amino acid family:Glutamate family:Histidine family" 52 "Energy production and conversion:Imidazoleglycerol-phosphate synthase:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Ketopantoate hydroxymethyltransferase:Anthranilate/para-aminobenzoate synthases component II:Anthranilate phosphoribosyltransferase:Transcriptional regulator:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Glutathione S-transferase:NAD-dependent aldehyde dehydrogenases:Zn-dependent alcohol dehydrogenases, class III:ATP-dependent protease Clp, ATPase subunit:N-acetylglutamate synthase (N-acetylornithine aminotransferase):Aspartate/tyrosine/aromatic aminotransferase:Uncharacterized protein required for cytochrome oxidase assembly:D-alanyl-D-alanine carboxypeptidase:Uncharacterized protein, possibly involved in aromatic compounds catabolism:ABC-type proline/glycine betaine transport systems, periplasmic components:Zn-dependent carboxypeptidase:O-acetylhomoserine sulfhydrylase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Ornithine/acetylornithine aminotransferase:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Oxidative phosphorylation:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Lysine biosynthesis:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Peptidoglycan biosynthesis:Inositol phosphate metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Propanoate metabolism:Methane metabolism:Pantothenate and CoA biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:ArgJ:panB:sensory_box:unchar_dom_1:clpX:trpG_papA:argD:hisF:TIGR01244:trpD:OAH_OAS_sulfhy:MMSDH:adh_III_F_hyde:ABC_choline_bnd:Serine family:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Amino acids and amines:Fermentation:Regulatory functions:Small molecule interactions:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Amino acids, peptides and amines:Hypothetical proteins:Conserved:Amino acid biosynthesis:Aromatic amino acid family:Glutamate family:Metabolism:Histidine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 53 "Predicted redox protein, regulator of disulfide bond formation:Glycine cleavage system H protein (lipoate-binding):Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain:Predicted flavoproteins:Amino acid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Glycine serine and threonine metabolism:Metabolic pathways:Sulfur relay system:General function prediction only:TIGR00275:gcvP:gcvH:Amino acids and amines:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Energy metabolism:Metabolism:Unknown function:Enzymes of unknown specificity:Cellular processes and signaling:Metabolism:Poorly characterized" 54 "Diaminopimelate decarboxylase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Pseudouridylate synthases, 23S RNA-specific:Transcriptional regulator:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Arsenite efflux pump ACR3 and related permeases:S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase):Transcription-repair coupling factor (superfamily II helicase):Primosomal protein N' (replication factor Y) - superfamily II helicase:Arsenate reductase and related proteins, glutaredoxin family:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Putative periplasmic protein kinase ArgK and related GTPases of G3E family:Transcriptional regulators:Threonine aldolase:Uncharacterized protein containing a von Willebrand factor type A (vWA) domain:Predicted membrane protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:CBS-domain-containing membrane protein:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Lysine biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:Nucleotide excision repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:rluA_subfam:queA:mfd:priA:lao:acr3:lysA:aProt_lowcomp:sigma70-ECF:Regulatory functions:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Replication and Repair:Transcription:Genetic Information Processing:tRNA and rRNA base modification:Amino Acid Metabolism:Transport and binding proteins:Anions:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Protein interactions" 55 "Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:ABC-type branched-chain amino acid transport systems, ATPase component:ABC-type branched-chain amino acid transport systems, ATPase component:Branched-chain amino acid ABC-type transport system, permease components:Transcriptional regulator:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:ABC-type branched-chain amino acid transport systems, periplasmic component:Catalase:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:ABC-type multidrug transport system, ATPase and permease components:Outer membrane receptor proteins, mostly Fe transport:ABC-type Fe3+ transport system, periplasmic component:Choline dehydrogenase and related flavoproteins:ABC-type branched-chain amino acid transport system, permease component:ABC-type enterochelin transport system, ATPase component:ABC-type enterochelin transport system, permease component:ABC-type enterochelin transport system, permease component:ABC-type enterochelin transport system, periplasmic component:TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component:TRAP-type mannitol/chloroaromatic compound transport system, large permease component:TRAP-type mannitol/chloroaromatic compound transport system, small permease component:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Tryptophan metabolism:Phosphonate and phosphinate metabolism:Methane metabolism:Limonene and pinene degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:dctM:TonB-siderophor:Defense mechanisms:Amino Acid Metabolism:Information storage and processing:Energy Metabolism:Cellular processes and signaling:Metabolism:Metabolism:Porins:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Metabolism:Global:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids" 56 "Mannitol-1-phosphate/altronate dehydrogenases:ABC-type sugar transport system, permease component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type sugar transport systems, permease components:Cold shock proteins:ABC-type sugar transport system, periplasmic component:Phosphate starvation-inducible protein PhoH, predicted ATPase:Uncharacterized host factor I protein:Acyl dehydratase:Uncharacterized conserved protein:ABC-type sugar transport systems, ATPase components:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Fructose and mannose metabolism:ABC transporters:Ribosome:RNA degradation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:S21p:Hfq:PPK2_P_aer:Phosphorus compounds:Central intermediary metabolism:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Metabolism:Translation:Genetic Information Processing:Other:Carbohydrate Metabolism:Protein synthesis:Ribosomal proteins: synthesis and modification:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Regulatory functions" 57 "Energy production and conversion:Site-specific DNA methylase:Nitrogen regulatory protein PII:Cytosine deaminase and related metal-dependent hydrolases:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Spermidine/putrescine-binding periplasmic protein:ABC-type dipeptide transport system, periplasmic component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Pyruvate carboxylase:Uncharacterized ABC-type transport system, permease component:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Predicted metal-dependent hydrolase:ABC-type sugar transport system, periplasmic component:Uncharacterized conserved protein:FOG: GGDEF domain:DNA-binding HTH domain-containing proteins:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type uncharacterized transport systems, ATPase components:ABC-type uncharacterized transport system, permease component:ABC-type uncharacterized transport system, permease component:Uncharacterized membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Pyrimidine metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Pyruvate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:dcm:ahpD_dom:potA:pyruv_carbox:Poorly characterized:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:General:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 58 "Energy production and conversion:Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain:Glycosyltransferase:FOG: CBS domain:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Peroxiredoxin:Fe2+/Zn2+ uptake regulation proteins:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Cold shock proteins:Methylase of chemotaxis methyl-accepting proteins:Uncharacterized conserved protein:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Predicted transcriptional regulators:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Uncharacterized conserved protein:Sugar transferases involved in lipopolysaccharide synthesis:Choline dehydrogenase and related flavoproteins:Cytochrome c2:Uncharacterized protein conserved in bacteria:Predicted integral membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Purine metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:PduO_Nterm:FGAM_synth_I:sigma70-ECF:Poorly characterized:Lipid Metabolism:Nucleotide Metabolism:Genetic Information Processing:Transcription:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Regulatory functions:Small molecule interactions:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 59 "Energy production and conversion:Histidinol dehydrogenase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Spermidine/putrescine-binding periplasmic protein:Permeases of the drug/metabolite transporter (DMT) superfamily:NAD-dependent aldehyde dehydrogenases:Enoyl-CoA hydratase/carnithine racemase:Predicted nucleoside-diphosphate sugar epimerases:Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):Predicted phosphohydrolases:Large-conductance mechanosensitive channel:Uncharacterized protein, possibly involved in aromatic compounds catabolism:GTPases:Predicted acetamidase/formamidase:Cytochrome c2:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Galactose metabolism:Ascorbate and aldarate metabolism:Fatty acid metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Limonene and pinene degradation:Nitrogen metabolism:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:hisD:mscL:GGDEF:SSADH:VCBS_repeat:GTP_HflX:1-PFK:Metabolism:Poorly characterized:Cellular processes:Other:Central intermediary metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism:Adaptations to atypical conditions:Carbohydrate Metabolism:Unknown function:General:Amino acid biosynthesis:Histidine family:Signal transduction:Other:Cellular processes and signaling" 60 "Transcriptional regulator:Methyl-accepting chemotaxis protein:Signal transduction histidine kinase regulating citrate/malate metabolism:Flp pilus assembly protein CpaB:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Flp pilus assembly protein TadG:Flp pilus assembly protein, ATPase CpaF:Flp pilus assembly protein, ATPase CpaE:Flp pilus assembly protein TadB:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Transcription:Cell motility:Two-component system:Bacterial chemotaxis:Function unknown:Signal transduction mechanisms:sensory_box:pilus_cpaB:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:Small molecule interactions:Regulatory functions:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Poorly characterized" 61 "Energy production and conversion:Xaa-Pro aminopeptidase:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Phosphoglycerate dehydrogenase and related dehydrogenases:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Uncharacterized NAD(FAD)-dependent dehydrogenases:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type polar amino acid transport system, ATPase component:Alcohol dehydrogenase, class IV:Uncharacterized proteins, homologs of lactam utilization protein B:TRAP-type C4-dicarboxylate transport system, large permease component:TRAP-type C4-dicarboxylate transport system, periplasmic component:Allophanate hydrolase subunit 2:Pyridoxal phosphate biosynthesis protein:Allophanate hydrolase subunit 1:Transcriptional regulators:Predicted acetamidase/formamidase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:TRAP-type mannitol/chloroaromatic compound transport system, small permease component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Glycine serine and threonine metabolism:Lysine biosynthesis:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:D-Arginine and D-ornithine metabolism:D-Alanine metabolism:Methane metabolism:Vitamin B6 metabolism:Atrazine degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00370:pdxA:urea_amlyse_rel:dctM:HEQRo_perm_3TM:hydantase:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pyridoxine:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Conserved:Hypothetical proteins:Carbohydrates, organic alcohols, and acids:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism" 62 "Energy production and conversion:Polyferredoxin:Zn-dependent protease with chaperone function:Biotin synthase and related enzymes:Transcriptional regulator:Glutathione S-transferase:Predicted membrane metal-binding protein:Zn-dependent alcohol dehydrogenases:Mg-chelatase subunit ChlD:Transcriptional regulator:Transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted N-acetylglucosamine kinase:Uncharacterized conserved protein:Predicted naringenin-chalcone synthase:Predicted transcriptional regulator:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Tyrosine metabolism:Glutathione metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Biotin metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ComEC_N-term:bioB:ccoG_rdxA_fixG:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Biotin:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 63 "Energy production and conversion:5-formyltetrahydrofolate cyclo-ligase:Diaminopimelate epimerase:Lipoate-protein ligase B:Cytosine deaminase and related metal-dependent hydrolases:Adenylate kinase and related kinases:K+ transport systems, NAD-binding component:2-methylthioadenine synthetase:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Predicted hydrolase (HAD superfamily):Transcriptional regulators:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:AraC-type DNA-binding domain-containing proteins:Mg/Co/Ni transporter MgtE (contains CBS domain):Predicted ATPase:Uncharacterized conserved protein:Predicted N-formylglutamate amidohydrolase:ABC-type oligopeptide transport system, periplasmic component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Lysine biosynthesis:One carbon pool by folate:Lipoic acid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:TIGR00089:lipB:mgtE:DapF:Ubi-OHases:Pyr-5-nucltdase:MTHFS_bact:guan_deamin:tRNA_sel_U_synt:Protein synthesis:Other:Purines, pyrimidines, nucleosides, and nucleotides:One-carbon metabolism:Central intermediary metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Protein fate:Nucleotide Metabolism:Protein modification and repair:Transport and binding proteins:Cations and iron carrying compounds:Amino acid biosynthesis:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Information storage and processing:Metabolism:Poorly characterized:tRNA and rRNA base modification" 64 "Energy production and conversion:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Mannitol-1-phosphate/altronate dehydrogenases:ABC-type sugar transport system, permease component:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis:Cation/multidrug efflux pump:Membrane-fusion protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Serine acetyltransferase:ABC-type sugar transport systems, permease components:NADH dehydrogenase, FAD-containing subunit:Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:ABC-type sugar transport system, periplasmic component:Transcriptional regulators:Acyl-CoA dehydrogenases:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:ABC-type sugar transport systems, ATPase components:ABC-type oligopeptide transport system, periplasmic component:Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits:Putative virion core protein (lumpy skin disease virus):Uncharacterized protein conserved in bacteria:Predicted secreted protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Glyoxylate and dicarboxylate metabolism:Nitrotoluene degradation:Methane metabolism:Pantothenate and CoA biosynthesis:Terpenoid backbone biosynthesis:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ispG_gcpE:ilvE_I:cysE:RND_mfp:Defense mechanisms:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Serine family:Pyruvate family:Amino acid biosynthesis:Unknown substrate:Transport and binding proteins:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 65 "Glutamine synthetase:Methionyl-tRNA formyltransferase:N-formylmethionyl-tRNA deformylase:ABC-type branched-chain amino acid transport systems, ATPase component:ABC-type branched-chain amino acid transport systems, ATPase component:Nucleotide-binding protein implicated in inhibition of septum formation:CTP synthase (UTP-ammonia lyase):Branched-chain amino acid ABC-type transport system, permease components:Uncharacterized conserved protein:GTPase:Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog):NAD(FAD)-utilizing enzyme possibly involved in translation:Ribonucleases G and E:Methylmalonyl-CoA mutase, N-terminal domain/subunit:Uncharacterized MobA-related protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:ABC-type arginine/histidine transport system, permease component:ABC-type branched-chain amino acid transport system, permease component:ABC-type arginine transport system, permease component:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Arginine and proline metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:One carbon pool by folate:Carbon fixation pathways in prokaryotes:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:pept_deformyl:gid_trmFO:maf:small_GTP:TIGR00278:PyrG:fmt:acid_CoA_mut_C:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesis:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Protein fate:Protein modification and repair:Cellular processes:Cell division:Hypothetical proteins:Conserved:Unknown function:General:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 66 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Acetyl-CoA acetyltransferase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Zn-dependent hydrolases, including glyoxylases:Predicted transcriptional regulators:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted acyl-CoA transferases/carnitine dehydratase:Acyl-CoA dehydrogenases:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Dioxygenases related to 2-nitropropane dioxygenase:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Uncharacterized conserved protein:Acetyl/propionyl-CoA carboxylase, alpha subunit:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Pyruvate metabolism:Naphthalene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:unchar_dom_1:HIBADH:AcCoA-C-Actrans:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Other:Carbohydrate Metabolism:Information storage and processing:Metabolism:Poorly characterized:Fatty acid and phospholipid metabolism:Amino acids and amines:Energy metabolism" 67 "Energy production and conversion:Purine nucleoside phosphorylase:Predicted Co/Zn/Cd cation transporters:Trk-type K+ transport systems, membrane components:Glutamine synthetase:DNA repair exonuclease:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Di- and tricarboxylate transporters:Transcriptional regulator:Glutathione S-transferase:Predicted transcriptional regulators:Predicted permeases:Nitroreductase:Sec-independent protein secretion pathway component TatC:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Enoyl-CoA hydratase/carnithine racemase:Uncharacterized ABC-type transport system, permease component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Phosphatidylserine synthase:Predicted transcriptional regulator containing the HTH domain:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:Acyl dehydratase:ABC-type histidine transport system, ATPase component:ABC-type uncharacterized transport system, permease component:Uncharacterized protein conserved in bacteria:Site-specific recombinase XerC:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Arginine and proline metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Glutathione metabolism:Peptidoglycan biosynthesis:Glycerophospholipid metabolism:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Limonene and pinene degradation:Nitrogen metabolism:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Protein export:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00281:tatC:CDF:PNPH-PUNA-XAPA:mono_pep_trsgly:Intracellular trafficking, secretion, and vesicular transport:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:DNA metabolism:Chromosome-associated proteins:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Cations and iron carrying compounds:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids" 68 "Chromatin structure and dynamics:Energy production and conversion:Xaa-Pro aminopeptidase:Pseudouridylate synthase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Uncharacterized conserved protein:Periplasmic serine proteases (ClpP class):Ferredoxin:Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Glycine/D-amino acid oxidases (deaminating):ABC-type branched-chain amino acid transport systems, periplasmic component:ABC-type sugar transport systems, permease components:ATPases involved in chromosome partitioning:Hemolysins and related proteins containing CBS domains:Transcriptional regulator:Transcriptional regulators:4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase:Uncharacterized conserved protein:ABC-type sugar transport systems, ATPase components:Predicted O-methyltransferase:Flp pilus assembly protein TadD, contains TPR repeats:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Phenylalanine metabolism:Pantothenate and CoA biosynthesis:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:hisT_truA:ispE:hemN_rel:urea_ABC_UrtA:PPK2_P_aer:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Environmental Information Processing:Membrane Transport:Global:Metabolism:Central intermediary metabolism:Phosphorus compounds:Protein synthesis:tRNA and rRNA base modification:Transport and binding proteins:Amino acids, peptides and amines:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Heme, porphyrin, and cobalamin:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 69 "Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Predicted Zn-dependent peptidases:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:CBS-domain-containing membrane protein:Membrane-bound metallopeptidase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Replication, recombination and repair:Lysine biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:parE_Gneg:dapE_proteo:Information storage and processing:Amino Acid Metabolism:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Amino acid biosynthesis:Aspartate family:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 70 "ABC-type branched-chain amino acid transport systems, periplasmic component:Spermidine/putrescine-binding periplasmic protein:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type polar amino acid transport system, ATPase component:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:ABC-type Fe3+ transport system, periplasmic component:ABC-type proline/glycine betaine transport systems, periplasmic components:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:TRAP-type uncharacterized transport system, periplasmic component:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type proline/glycine betaine transport system, ATPase component:ABC-type proline/glycine betaine transport system, permease component:ABC-type amino acid transport system, permease component:TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component:Amino acid transport and metabolism:Transcription:Inorganic ion transport and metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:potA:HEQRo_perm_3TM:TRAP_TAXI:ABC_choline_bnd:ABC_choXWV_ATP:ABC_choXWV_perm:Transport and binding proteins:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Amino acids, peptides and amines:Unknown substrate" 71 "Cysteine synthase:Glycine/serine hydroxymethyltransferase:Tryptophanyl-tRNA synthetase:Short-chain dehydrogenases of various substrate specificities:4-hydroxybenzoate polyprenyltransferase and related prenyltransferases:Glycine cleavage system T protein (aminomethyltransferase):Zn-dependent protease with chaperone function:Signal recognition particle GTPase:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Glutathione S-transferase:Cystathionine beta-lyases/cystathionine gamma-synthases:Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA:Integral membrane protein CcmA involved in cell shape determination:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Rhodanese-related sulfurtransferase:Thioredoxin domain-containing protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Tryptophan metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:One carbon pool by folate:Methane metabolism:Nitrogen metabolism:Sulfur metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Bacterial chemotaxis:Flagellar assembly:Protein export:Bacterial secretion system:Sulfur relay system:General function prediction only:Function unknown:ftsY:trpS:gcvT:thioredoxin:O_suc_HS_sulf:ubiA_proteo:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Protein synthesis:Electron transport:Amino acids and amines:Energy metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Membrane Transport:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:tRNA aminoacylation:Energy Metabolism:Protein fate:Protein and peptide secretion and trafficking:Amino acid biosynthesis:Aspartate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Information storage and processing:Cellular processes and signaling" 72 "NAD synthase:Pyridoxamine-phosphate oxidase:Aspartate/tyrosine/aromatic aminotransferase:Predicted acid phosphatase:Cytosine/adenosine deaminases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Enoyl-[acyl-carrier-protein] reductase (NADH):Alanine dehydrogenase:Lhr-like helicases:CMP-2-keto-3-deoxyoctulosonic acid synthetase:Putative threonine efflux protein:Uncharacterized protein conserved in bacteria:Predicted ICC-like phosphoesterases:Uncharacterized protein conserved in bacteria:Glucose/sorbosone dehydrogenases:Protein-L-isoaspartate carboxylmethyltransferase:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Peptide chain release factor RF-3:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fructose and mannose metabolism:Fatty acid biosynthesis:Purine metabolism:Pyrimidine metabolism:Lysine biosynthesis:Lysine degradation:Bisphenol degradation:Lipopolysaccharide biosynthesis:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Vitamin B6 metabolism:Nicotinate and nicotinamide metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:pimt:surE:small_GTP:nadE:pdxH:Protein modification and repair:Protein fate:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Pyridoxine:Carbohydrate Metabolism:Pyridine nucleotides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Adaptations to atypical conditions:Cellular processes" 73 "Energy production and conversion:Site-specific DNA methylase:Periplasmic serine proteases (ClpP class):Transcriptional regulator:DNA repair photolyase:Flagellar motor switch protein:ABC-type sugar transport system, periplasmic component:Na+/H+ antiporter:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Serine phosphatase RsbU, regulator of sigma subunit:Uncharacterized protein conserved in bacteria:Uncharacterized metal-binding protein:Trimethylamine:corrinoid methyltransferase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Methane metabolism:Microbial metabolism in diverse environments:ABC transporters:Bacterial chemotaxis:Flagellar assembly:Mismatch repair:General function prediction only:Function unknown:Signal transduction mechanisms:antiport_nhaC:LLM_2I7G:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Energy Metabolism:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Cellular Processes:Cell Motility:Global:Metabolism:Transport and binding proteins:Cations and iron carrying compounds:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 74 "Energy production and conversion:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:MoxR-like ATPases:Predicted amidophosphoribosyltransferases:Uncharacterized conserved protein:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):DNA replication protein:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:ATP-dependent DNA ligase:Topoisomerase IB:Phage terminase, small subunit:Uncharacterized protein conserved in bacteria:Phage terminase-like protein, large subunit:Signal transduction histidine kinase:Lipid transport and metabolism:Replication, recombination and repair:Inorganic ion transport and metabolism:Purine metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Base excision repair:Nucleotide excision repair:Mismatch repair:Non-homologous end-joining:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ant_ant_sig:sm_term_P27:Ku_bact:NHEJ_ligase_prk:Information storage and processing:Nucleotide Metabolism:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Regulatory functions:Protein interactions:DNA metabolism:DNA replication, recombination, and repair:Mobile and extrachromosomal element functions:Prophage functions:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 75 "Energy production and conversion:Ribosomal protein L33:Ribosomal protein S20:Ribosomal protein L32:Translation initiation factor 1 (IF-1):Preprotein translocase subunit SecE:Fe2+/Zn2+ uptake regulation proteins:Ferredoxin:DNA-directed RNA polymerase, subunit K/omega:Uncharacterized protein conserved in bacteria:DNA uptake lipoprotein:Uncharacterized protein conserved in bacteria:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Ribosome:RNA polymerase:Protein export:Bacterial secretion system:General function prediction only:Function unknown:infA:S20:rpoZ:secE_bact:rpmJ_bact:rpmG_bact:rpmH_bact:rpmF_bact:OM_YfiO:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Nucleotide Metabolism:Genetic Information Processing:Transcription:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transcription:DNA-dependent RNA polymerase:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 76 "Replicative DNA helicase:Lactoylglutathione lyase and related lyases:Methylated DNA-protein cysteine methyltransferase:Predicted dehydrogenases and related proteins:Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria):Sugar phosphate isomerases/epimerases:Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):ABC-type sugar transport system, ATPase component:Phosphotransferase system, fructose-specific IIC component:Transcriptional regulators:Predicted acyltransferases:ABC-type sugar transport system, periplasmic component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Fructose and mannose metabolism:Metabolic pathways:ABC transporters:Bacterial chemotaxis:Phosphotransferase system (PTS):DNA replication:General function prediction only:ogt:DnaB:FRU:PTS_HPr_family:TAT_signal_seq:1-PFK:Poorly characterized:Carbohydrate Metabolism:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Cellular Processes:Cell Motility:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein and peptide secretion and trafficking:Signal transduction:PTS:Information storage and processing:Metabolism:Metabolism" 77 "Energy production and conversion:Chaperonin GroEL (HSP60 family):Fucose permease:Methyl-accepting chemotaxis protein:NAD-dependent aldehyde dehydrogenases:ABC-type spermidine/putrescine transport system, permease component II:NADH dehydrogenase, FAD-containing subunit:Transcriptional regulator:TRAP-type C4-dicarboxylate transport system, large permease component:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Heme/copper-type cytochrome/quinol oxidases, subunit 2:TRAP-type C4-dicarboxylate transport system, periplasmic component:Transcriptional regulators:Predicted metal-dependent hydrolase of the TIM-barrel fold:Choline dehydrogenase and related flavoproteins:Transposase and inactivated derivatives:TRAP-type C4-dicarboxylate transport system, small permease component:Response regulator with putative antiterminator output domain:Uncharacterized protein conserved in bacteria:Phage terminase-like protein, large subunit:Predicted phage phi-C31 gp36 major capsid-like protein:Uncharacterized protein with a bacterial SH3 domain homologue:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Glycine serine and threonine metabolism:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:RNA degradation:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:dctM:BADH:betA:sigma70-ECF:Nterm_to_SelD:betaine_BetI:Regulatory functions:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Folding Sorting and Degradation:Metabolism:Transcription:Genetic Information Processing:Amino Acid Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Adaptations to atypical conditions:Cellular processes:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:DNA interactions" 78 "GTPases - translation elongation factors:Indole-3-glycerol phosphate synthase:Ribosomal protein S17:Translation elongation factors (GTPases):Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:DnaK suppressor protein:Bacteriophage head-tail adaptor:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Phenylalanine tyrosine and tryptophan biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Ribosome:General function prediction only:Signal transduction mechanisms:small_GTP:hemN:gp16_SPP1:S17_bact:Unknown function:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Protein synthesis:Ribosomal proteins: synthesis and modification:Mobile and extrachromosomal element functions:Prophage functions:Metabolism:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 79 "Energy production and conversion:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Acetyl-CoA acetyltransferase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Serine/threonine protein kinase:ATPases with chaperone activity, ATP-binding subunit:NAD-dependent aldehyde dehydrogenases:Phytoene dehydrogenase and related proteins:3-hydroxyacyl-CoA dehydrogenase:Predicted metal-dependent hydrolase of the TIM-barrel fold:Hemolysin-coregulated protein (uncharacterized):Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein, contains FHA domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Arginine and proline metabolism:Benzoate degradation:alpha-Linolenic acid metabolism:Ethylbenzene degradation:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:AcCoA-C-Actrans:VI_ClpV1:VI_chp_1:VI_IcmF:IV_VI_DotU:VI_chp_3:VI_chp_4:VI_FHA:VI_chp_2:VI_zyme:VI_chp_5:VI_chp_6:Cellular processes:Other:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Pathogenesis" 80 "FOG: CheY-like receiver:Signal transduction mechanisms:Cellular processes and signaling" 81 "Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Predicted flavoprotein:ADP-glucose pyrophosphorylase:Nucleoside-diphosphate-sugar epimerases:Glutathione S-transferase:ABC-type branched-chain amino acid transport systems, periplasmic component:Penicillin tolerance protein:Bacterial nucleoid DNA-binding protein:Putative threonine efflux protein:Transcriptional regulators:Uncharacterized protein containing LysM domain:Phosphohistidine phosphatase SixA:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Large extracellular alpha-helical protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Valine leucine and isoleucine degradation:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:Signal transduction mechanisms:ispH_lytB:himA:hip:glgC:diverge_rpsU:DNA replication, recombination, and repair:DNA metabolism:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function" 82 "ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:MoxR-like ATPases:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Predicted exonuclease of the beta-lactamase fold involved in RNA processing:Transglutaminase-like enzymes, putative cysteine proteases:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):ATP-dependent DNA ligase:Acyl-CoA dehydrogenases:AraC-type DNA-binding domain-containing proteins:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted proteasome-type protease:Murein endopeptidase:Uncharacterized protein conserved in bacteria:Uncharacterized protein containing double-stranded beta helix domain:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Base excision repair:Nucleotide excision repair:Mismatch repair:Non-homologous end-joining:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Global:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism:Metabolism of Terpenoids and Polyketides:Poorly characterized:Metabolism of Other Amino Acids:Metabolism:Amino Acid Metabolism:Lipid Metabolism:Cellular processes and signaling:Information storage and processing:Carbohydrate Metabolism:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Membrane Transport" 83 "Energy production and conversion:Dihydroxyacid dehydratase/phosphogluconate dehydratase:Dihydroorotate dehydrogenase:Ribosomal protein S6:Isocitrate/isopropylmalate dehydrogenase:Transcriptional regulator:Signal transduction histidine kinase:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Predicted membrane protein:Ni,Fe-hydrogenase I small subunit:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:FOG: PAS/PAC domain:AraC-type DNA-binding domain-containing proteins:Phage terminase, small subunit:Phage terminase-like protein, large subunit:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Valine leucine and isoleucine biosynthesis:Glyoxylate and dicarboxylate metabolism:Butanoate metabolism:Methane metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Ribosome:General function prediction only:Function unknown:Signal transduction mechanisms:S6:sensory_box:yihY_not_rbn:pyrD_sub1_fam:sm_term_P27:phge_HK97_gp10:TTC:Prophage functions:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:Other:Regulatory functions:Small molecule interactions:Protein synthesis:Ribosomal proteins: synthesis and modification:Mobile and extrachromosomal element functions:Metabolism:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 84 "Methionine aminopeptidase:Ribonuclease HII:Formamidopyrimidine-DNA glycosylase:Folate-dependent phosphoribosylglycinamide formyltransferase PurN:3-dehydroquinate synthetase:Predicted hydrolase of the metallo-beta-lactamase superfamily:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Tetraacyldisaccharide-1-P 4'-kinase:Transcriptional regulators:Allophanate hydrolase subunit 2:Allophanate hydrolase subunit 1:K+-transporting ATPase, A chain:K+-transporting ATPase, c chain:Osmosensitive K+ channel histidine kinase:High-affinity K+ transport system, ATPase chain B:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Predicted permeases:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):Site-specific recombinase XerD:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Lipopolysaccharide biosynthesis:One carbon pool by folate:Atrazine degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:DNA replication:Base excision repair:General function prediction only:Signal transduction mechanisms:TIGR00370:met_pdase_I:fpg:PurN:kdpA:kdpC:lpxK:urea_amlyse_rel:aroB:ATPase_P-type:potass_kdpF:PhoB:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Signal Transduction:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein modification and repair:Transport and binding proteins:Cations and iron carrying compounds:Hypothetical proteins:Conserved:Unknown function:General:Amino acid biosynthesis:Aromatic amino acid family:Signal transduction:Two-component systems:Cell envelope:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 85 "Energy production and conversion:Phosphoglycerate dehydrogenase and related dehydrogenases:Glycine/serine hydroxymethyltransferase:Delta-aminolevulinic acid dehydratase:Tryptophan synthase beta chain:S-adenosylmethionine synthetase:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Glycine/D-amino acid oxidases (deaminating):Penicillin tolerance protein:Lactate dehydrogenase and related dehydrogenases:4-diphosphocytidyl-2-methyl-D-erithritol synthase:Putative threonine efflux protein:Phosphoserine aminotransferase:Predicted transcriptional regulator:Methylase involved in ubiquinone/menaquinone biosynthesis:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Bisphenol degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Selenocompound metabolism:Cyanoamino acid metabolism:Chloroalkane and chloroalkene degradation:Butanoate metabolism:One carbon pool by folate:Methane metabolism:Vitamin B6 metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Signal transduction mechanisms:ispH_lytB:trpB:ispD:rrf2_super:metK:PGDH:serC_2:MenG_MenH_UbiE:UbiG:Menaquinone and ubiquinone:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Central intermediary metabolism:Other:Unknown function:General:Amino acid biosynthesis:Aromatic amino acid family:Serine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 86 "Energy production and conversion:Uroporphyrinogen-III methylase:Sulfite reductase, beta subunit (hemoprotein):3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:ABC-type sulfate transport system, permease component:Adenylate kinase and related kinases:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Sugar (pentulose and hexulose) kinases:Transcriptional regulators:Transcriptional regulator/sugar kinase:Xylose isomerase:Uncharacterized protein conserved in bacteria:ABC-type spermidine/putrescine transport systems, ATPase components:Predicted symporter:ABC-type sulfate transport system, periplasmic component:ABC-type sulfate transport system, permease component:ABC-type xylose transport system, periplasmic component:ABC-type xylose transport system, permease component:Predicted membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Purine metabolism:Pyruvate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Porphyrin and chlorophyll metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:cysH:3a0106s01:3a0106s02:3a0106s03:XylB:adk:cobA_cysG_Cterm:Ac_CoA_lig_AcsA:xylose_isom_A:xylF:Na_symport_sm:Na_symport_lg:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Energy Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Carbohydrate Metabolism:Nucleotide and nucleoside interconversions:Transport and binding proteins:Unknown substrate:Anions:Carbohydrates, organic alcohols, and acids:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Sugars:Energy metabolism:Sulfur metabolism:Central intermediary metabolism:Metabolism" 87 "Energy production and conversion:Dimethyladenosine transferase (rRNA methylation):Dephospho-CoA kinase:3-oxoacyl-(acyl-carrier-protein) synthase:Predicted enzyme with a TIM-barrel fold:Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division:Nucleotide-binding protein implicated in inhibition of septum formation:NAD/FAD-utilizing enzyme apparently involved in cell division:Predicted GTPase:Signal transduction histidine kinase:ABC-type transport system involved in resistance to organic solvents, permease component:Bacterial cell division membrane protein:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:ABC-type transport system involved in resistance to organic solvents, ATPase component:Organic solvent tolerance protein OstA:ABC-type transport system involved in resistance to organic solvents, periplasmic component:Predicted transcriptional regulators:Cell shape-determining protein:Phosphotransferase system, HPr-related proteins:Pyridoxal phosphate biosynthesis protein:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport system, auxiliary component:NADH:ubiquinone oxidoreductase 17.2 kD subunit:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Fatty acid biosynthesis:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Vitamin B6 metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:DNA replication:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00044:TIGR00056:gidA:gidB:TIGR00152:parB_part:mreC:small_GTP:pdxA:dnaq:ksgA:PTS_HPr_family:rodA_shape:Pantothenate and coenzyme A:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Global:Metabolism:DNA metabolism:Degradation of DNA:Protein synthesis:tRNA and rRNA base modification:Cellular processes:Cell division:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Pyridoxine:Signal transduction:PTS:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 88 "Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Predicted amidohydrolase:Predicted dehydrogenases and related proteins:Permeases of the drug/metabolite transporter (DMT) superfamily:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Sugar phosphate isomerases/epimerases:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:ABC-type sugar transport systems, permease components:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Predicted transcriptional regulators:Uncharacterized protein conserved in bacteria:AraC-type DNA-binding domain-containing proteins:ABC-type maltose transport systems, permease component:ABC-type spermidine/putrescine transport systems, ATPase components:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Inorganic ion transport and metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Aminobenzoate degradation:Styrene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:efflux_EmrB:lysidine_TilS_N:Membrane Transport:Environmental Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:tRNA and rRNA base modification:Carbohydrate Metabolism:Transport and binding proteins:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Protein synthesis:Metabolism:Global" 89 "N-methylhydantoinase A/acetone carboxylase, beta subunit:N-methylhydantoinase B/acetone carboxylase, alpha subunit:Glycine/D-amino acid oxidases (deaminating):Permeases of the drug/metabolite transporter (DMT) superfamily:Predicted transcriptional regulators:Panthothenate kinase:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:ABC-type sugar transport systems, permease components:Predicted transcriptional regulators:ABC-type sugar transport system, periplasmic component:Uncharacterized conserved protein:ABC-type sugar transport system, periplasmic component:Transcriptional regulator/sugar kinase:Cation transport ATPase:Predicted phosphosugar isomerases:Predicted N-acetylglucosamine kinase:Predicted enzyme of the cupin superfamily:ABC-type sugar transport systems, ATPase components:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:ATPase_P-type:Global:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Metabolism:Metabolism:Carbohydrate Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized:Metabolism" 90 "Chemotaxis protein histidine kinase and related kinases:FOG: CheY-like receiver:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:ATPases involved in chromosome partitioning:Flagellin and related hook-associated proteins:Flagellar capping protein:Methylase of chemotaxis methyl-accepting proteins:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Flagellin-specific chaperone FliS:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Two-component system:Bacterial chemotaxis:Flagellar assembly:RNA polymerase:Function unknown:Signal transduction mechanisms:rpoN_sigma:FlgM_jcvi:Intracellular trafficking, secretion, and vesicular transport:Transcription:Information storage and processing:Cellular processes and signaling:Poorly characterized:Genetic Information Processing:Transcription:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Transcription factors" 91 "Energy production and conversion:Fe-S oxidoreductase:FAD/FMN-containing dehydrogenases:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:DnaJ-class molecular chaperone with C-terminal Zn finger domain:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Mg2+ and Co2+ transporters:Predicted transcriptional regulators:Small-conductance mechanosensitive channel:NAD-dependent aldehyde dehydrogenases:Predicted ATP-dependent serine protease:ABC-type transport system involved in resistance to organic solvents, ATPase component:Transcriptional regulator:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:Predicted hydrolases of HD superfamily:Homoserine trans-succinylase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Transcriptional accessory protein:Transcriptional regulators:Predicted membrane protein:Uncharacterized conserved protein:Predicted enzyme related to lactoylglutathione lyase:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Flp pilus assembly protein TadD, contains TPR repeats:Uncharacterized conserved protein:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Lysine biosynthesis:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Chlorocyclohexane and chlorobenzene degradation:Bisphenol degradation:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Pyruvate metabolism:Toluene degradation:Polycyclic aromatic hydrocarbon degradation:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Limonene and pinene degradation:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:sms:metA:DnaJ_bact:PPK2_P_aer:Intracellular trafficking, secretion, and vesicular transport:Phosphorus compounds:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Central intermediary metabolism:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 92 "N-formylmethionyl-tRNA deformylase:Protein-tyrosine-phosphatase:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Transcriptional regulator:ATP:corrinoid adenosyltransferase:Bacterioferritin (cytochrome b1):Large extracellular alpha-helical protein:Uncharacterized protein involved in outer membrane biogenesis:Uncharacterized protein involved in response to NO:Signal transduction histidine kinase, glucose-6-phosphate specific:Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase:Membrane carboxypeptidase/penicillin-binding protein PbpC:Signal transduction histidine kinase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pyrimidine metabolism:beta-Alanine metabolism:Peptidoglycan biosynthesis:Pantothenate and CoA biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:pept_deformyl:sensory_box:cobA:bfr:hydantase:PBP_1c:Cell envelope:Nucleotide Metabolism:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Regulatory functions:Small molecule interactions:Protein fate:Protein modification and repair:Transport and binding proteins:Cations and iron carrying compounds:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Metabolism:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 93 "Glutamyl- and glutaminyl-tRNA synthetases:Imidazoleglycerol-phosphate dehydratase:Tryptophan synthase alpha chain:Glutamine synthetase:dGTP triphosphohydrolase:Stress-induced morphogen (activity unknown):Nitrogen regulatory protein PII:RecA/RadA recombinase:MoxR-like ATPases:Actin-like ATPase involved in cell morphogenesis:Lhr-like helicases:Predicted metal-dependent hydrolase:SOS-response transcriptional repressors (RecA-mediated autopeptidases):Transcriptional regulators:Predicted Zn peptidase:DNA-binding protein H-NS:Uncharacterized protein conserved in bacteria:Site-specific recombinase XerD:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Purine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Histidine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:trpA:gltX_bact:lexA:GlnA:mreB:dGTP_triPase:PD_CobS:tigrfam_recA:FYDLN_acid:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Metabolism:Signal Transduction:Environmental Information Processing:Replication and Repair:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Regulatory functions:Energy Metabolism:DNA interactions:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Amino acid biosynthesis:Aromatic amino acid family:Glutamate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan" 94 "Energy production and conversion:Predicted TIM-barrel enzyme:Sugar kinases, ribokinase family:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Putative transcription activator:Uncharacterized Fe-S protein:Transcriptional regulators:Cytochrome c553:Predicted ATPase:Signal transduction histidine kinase:Carbohydrate transport and metabolism:Transcription:Pentose phosphate pathway:Thiamine metabolism:General function prediction only:Signal transduction mechanisms:sensory_box:thylakoid_BtpA:Protein fate:Small molecule interactions:Regulatory functions:Metabolism of Cofactors and Vitamins:Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Protein folding and stabilization" 95 "Chromatin structure and dynamics:Energy production and conversion:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Cytosine deaminase and related metal-dependent hydrolases:Transcriptional regulator:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Predicted transcriptional regulators:ABC-type dipeptide transport system, periplasmic component:Cation/multidrug efflux pump:Membrane-fusion protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ATPase components of various ABC-type transport systems, contain duplicated ATPase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Imidazolonepropionase and related amidohydrolases:Transcriptional regulator:Uncharacterized conserved protein:Cobyric acid synthase:Transcriptional regulators:Transcriptional regulators:Histidine ammonia-lyase:Urocanate hydratase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Lysine biosynthesis:Arginine and proline metabolism:Histidine metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Styrene degradation:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:cobQ:hutI:hutH:hutU:rocF_arginase:RND_mfp:DapE-ArgE:hutF:oxido_YhdH:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Unknown substrate:Transport and binding proteins:Degradation of proteins, peptides, and glycopeptides:Protein fate:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Poorly characterized:Metabolism" 96 "Glycogen synthase:Superoxide dismutase:Predicted acyltransferases:Putative Mg2+ and Co2+ transporter CorB:Carbohydrate transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Starch and sucrose metabolism:Metabolic pathways:glgA:Biosynthesis and degradation of polysaccharides:Carbohydrate Metabolism:Global:Metabolism:Energy metabolism:Metabolism:Metabolism" 97 "Energy production and conversion:7-keto-8-aminopelargonate synthetase and related enzymes:Zn-dependent oligopeptidases:Lactoylglutathione lyase and related lyases:Cytosine deaminase and related metal-dependent hydrolases:Transcriptional regulator:Uncharacterized membrane protein (homolog of Drosophila rhomboid):5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:Diacylglycerol kinase:Zn-dependent alcohol dehydrogenases, class III:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Imidazolonepropionase and related amidohydrolases:Cobalamin biosynthesis protein CobD/CbiB:Transglutaminase-like enzymes, putative cysteine proteases:Transcriptional regulator:Transcriptional regulators:Uncharacterized conserved protein:Transcriptional regulators:Transcriptional regulators:Histidine ammonia-lyase:Urocanate hydratase:N-acyl-L-homoserine lactone synthetase:Transcriptional regulator, effector-binding domain/component:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Histidine metabolism:Tyrosine metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Nicotinate and nicotinamide metabolism:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:cobD:ahpD_dom:hutI:hutH:hutU:2am3keto_CoA:hutF:Lipid Metabolism:Energy Metabolism:General:Carbohydrate Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Unknown function:Amino acids and amines:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism" 98 "NAD-dependent DNA ligase (contains BRCT domain type II):NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Predicted transcriptional regulators:Deoxycytidine deaminase:Metal-dependent amidase/aminoacylase/carboxypeptidase:Membrane transporters of cations and cationic drugs:Amino acid transport and metabolism:Nucleotide transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Phenylalanine metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:DNA replication:Base excision repair:Nucleotide excision repair:Mismatch repair:General function prediction only:dnlj:gltD_gamma_fam:amidohydrolases:Degradation of proteins, peptides, and glycopeptides:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Metabolism:Information storage and processing:Metabolism:Poorly characterized" 99 "Esterase/lipase:NAD-dependent protein deacetylases, SIR2 family:Pyridoxal/pyridoxine/pyridoxamine kinase:Uncharacterized protein conserved in bacteria:Transcriptional regulator, contains sigma factor-related N-terminal domain:Signal transduction histidine kinase, nitrogen specific:Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Amino sugar and nucleotide sugar metabolism:Vitamin B6 metabolism:Metabolic pathways:Two-component system:Function unknown:Signal transduction mechanisms:pyridox_kin:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridoxine:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 100 "Geranylgeranyl pyrophosphate synthase:4-aminobutyrate aminotransferase and related aminotransferases:ABC-type Co2+ transport system, permease component:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:ABC-type cobalt transport system, permease component CbiQ and related transporters:Glycine/D-amino acid oxidases (deaminating):1-deoxy-D-xylulose 5-phosphate reductoisomerase:Urease accessory protein UreH:Urea amidohydrolase (urease) gamma subunit:Urea amidohydrolase (urease) beta subunit:Deoxyxylulose-5-phosphate synthase:4-diphosphocytidyl-2-methyl-D-erithritol synthase:Predicted glycosyltransferases:Phosphatidylglycerophosphatase A and related proteins:Uncharacterized protein (competence- and mitomycin-induced):Exonuclease VII small subunit:Putative homoserine kinase type II (protein kinase fold):Arabinose efflux permease:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Arginine and proline metabolism:Glycerophospholipid metabolism:Atrazine degradation:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Mismatch repair:General function prediction only:urease_beta:urease_gam:cinA_cterm:dxs:Dxr:ispD:xseB:CbiQ_TIGR:Degradation of DNA:DNA metabolism:Nitrogen metabolism:Central intermediary metabolism:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Nucleotide Metabolism:DNA replication, recombination, and repair:Lipid Metabolism:Transport and binding proteins:Cations and iron carrying compounds:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Thiamine:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 101 "Gamma-glutamyl phosphate reductase:5-formyltetrahydrofolate cyclo-ligase:Acyl carrier protein:Transcriptional regulator:Transcriptional regulator:Uncharacterized conserved protein:Uncharacterized conserved protein:Predicted membrane protein involved in D-alanine export:Acyl dehydratase:3-methyladenine DNA glycosylase:Uncharacterized protein conserved in bacteria:Predicted enzyme involved in methoxymalonyl-ACP biosynthesis:Membrane-bound metallopeptidase:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Arginine and proline metabolism:One carbon pool by folate:Metabolic pathways:Base excision repair:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:proA:3mg:TIGR00726:HAD-SF-IIIC:MTHFS_bact:Cellular processes and signaling:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Global:Metabolism:Central intermediary metabolism:One-carbon metabolism:DNA metabolism:DNA replication, recombination, and repair:Unknown function:General:Amino acid biosynthesis:Glutamate family:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 102 "Energy production and conversion:EMAP domain:Glutamine synthetase:Pyrroline-5-carboxylate reductase:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Predicted esterase:Predicted permeases:Spermidine/putrescine-binding periplasmic protein:Predicted xylanase/chitin deacetylase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:NAD-dependent aldehyde dehydrogenases:Lactate dehydrogenase and related dehydrogenases:Transcriptional regulator:Uncharacterized conserved protein:Alcohol dehydrogenase, class IV:Uncharacterized protein conserved in bacteria:Transcriptional regulators:Predicted metal-dependent hydrolase:Uncharacterized conserved protein:TRAP-type uncharacterized transport system, periplasmic component:Uncharacterized protein, possibly involved in glyoxylate utilization:Signal transduction histidine kinase:Predicted N-formylglutamate amidohydrolase:TRAP-type mannitol/chloroaromatic compound transport system, large permease component:TRAP-type mannitol/chloroaromatic compound transport system, small permease component:Membrane carboxypeptidase/penicillin-binding protein PbpC:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Geraniol degradation:Lysine biosynthesis:Arginine and proline metabolism:Bisphenol degradation:beta-Alanine metabolism:Peptidoglycan biosynthesis:Polycyclic aromatic hydrocarbon degradation:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Butanoate metabolism:Methane metabolism:Pantothenate and CoA biosynthesis:Limonene and pinene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:proC:ahpD_dom:hydantase:DapE-ArgE:PBP_1c:TRAP_TAXI:chap_CsaA:fghA_ester_D:UHCUDC:ura-cupin:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Protein fate:Protein and peptide secretion and trafficking:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Unknown substrate:Cellular processes:Detoxification:Unknown function:General:Amino acid biosynthesis:Glutamate family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism" 103 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Site-specific DNA methylase:ABC-type branched-chain amino acid transport systems, ATPase component:Chaperonin GroEL (HSP60 family):Branched-chain amino acid ABC-type transport system, permease components:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Site-specific recombinases, DNA invertase Pin homologs:Predicted metal-dependent hydrolase of the TIM-barrel fold:AraC-type DNA-binding domain-containing proteins:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF:Cytochrome b:Phage head maturation protease:Uncharacterized conserved protein:Hydantoin racemase:ABC-type branched-chain amino acid transport system, permease component:Uncharacterized protein containing caspase domain:Uncharacterized ABC-type transport system, ATPase component:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Valine leucine and isoleucine degradation:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:RNA degradation:RNA polymerase:Mismatch repair:General function prediction only:Function unknown:proheadase_HK97:sigma70-ECF:urea_trans_UrtC:urea_trans_UrtB:urea_trans_UrtE:urea_trans_UrtD:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Metabolism:Transcription:Genetic Information Processing:Amino Acid Metabolism:Information storage and processing:Energy Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Amino acids, peptides and amines:Transport and binding proteins:Other:Protein fate:Metabolism" 104 "Ribosomal protein S2:Ribosomal protein L11:Ribosomal protein L1:DNA-directed RNA polymerase, beta' subunit/160 kD subunit:Ribosomal protein S5:Transcription elongation factor:Ribosomal protein L16/L10E:Ribosomal protein L15:Ribosomal protein L7/L12:Co-chaperonin GroES (HSP10):Transcription antiterminator:Translation elongation factor Ts:Ribosomal protein L9:Chaperonin GroEL (HSP60 family):Translation initiation factor 2 (IF-2; GTPase):Uncharacterized protein conserved in bacteria:Ribosomal protein L25 (general stress protein Ctc):Ribosomal protein L30/L7E:Predicted nucleic-acid-binding protein implicated in transcription termination:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:Ribosome:RNA degradation:RNA polymerase:Function unknown:tsf:L9:small_GTP:ctc_TL5:L12:nusG:rpsB_bact:rpsE_bact:rplO_bact:rplP_bact:rplA_bact:rpmD_bact:L11_bact:NusA:rpoB:GroEL:rpoC_TIGR:Metabolism:Global:Folding Sorting and Degradation:Translation:Transcription:Genetic Information Processing:DNA-dependent RNA polymerase:Nucleotide Metabolism:Transcription factors:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Protein fate:Protein folding and stabilization:Unknown function:General:Information storage and processing:Cellular processes and signaling:Poorly characterized:Transcription:Metabolism" 105 "Energy production and conversion:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:Predicted choline kinase involved in LPS biosynthesis:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Predicted dehydrogenases and related proteins:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:ABC-type dipeptide transport system, periplasmic component:NAD-dependent aldehyde dehydrogenases:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:ATPase components of various ABC-type transport systems, contain duplicated ATPase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type spermidine/putrescine transport system, permease component I:Co/Zn/Cd efflux system component:ABC-type proline/glycine betaine transport systems, periplasmic components:Transcriptional regulators:Histidine ammonia-lyase:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase:ABC-type proline/glycine betaine transport system, ATPase component:ABC-type proline/glycine betaine transport system, permease component:Integral membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Ascorbate and aldarate metabolism:Pyrimidine metabolism:Tyrosine metabolism:beta-Alanine metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Pantothenate and CoA biosynthesis:Nitrogen metabolism:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:proV:CDF:hydantase:KdgD:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds:Amino acids, peptides and amines:Transport and binding proteins:Metabolism" 106 "Spermidine/putrescine-binding periplasmic protein:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Exonuclease VII, large subunit:ABC-type sugar transport system, periplasmic component:Zn-dependent dipeptidase, microsomal dipeptidase homolog:DNA-binding HTH domain-containing proteins:ABC-type spermidine/putrescine transport systems, ATPase components:Predicted ATPase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Mismatch repair:General function prediction only:xseA:potA:Amino acids, peptides and amines:Transport and binding proteins:Degradation of DNA:DNA metabolism:Genetic Information Processing:Replication and Repair:Poorly characterized:Metabolism:Information storage and processing" 107 "Energy production and conversion:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Phosphoribosyl-ATP pyrophosphohydrolase:Shikimate 5-dehydrogenase:Lactoylglutathione lyase and related lyases:Ribonuclease D:Methylated DNA-protein cysteine methyltransferase:Phosphatidylglycerophosphate synthase:2-methylthioadenine synthetase:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Parvulin-like peptidyl-prolyl isomerase:FOG: CheY-like receiver:Uncharacterized homolog of plant Iojap protein:NAD-dependent aldehyde dehydrogenases:Transcriptional regulators:Multidrug resistance efflux pump:Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component:Ketopantoate reductase:Pyrimidine reductase, riboflavin biosynthesis:Chromate transport protein ChrA:Membrane transporters of cations and cationic drugs:AraC-type DNA-binding domain-containing proteins:Methylase involved in ubiquinone/menaquinone biosynthesis:Putative glycerate kinase:Uncharacterized conserved protein:Uncharacterized protein involved in cation transport:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase:Predicted membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid metabolism:Purine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Lysine biosynthesis:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Tryptophan metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:beta-Alanine metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Riboflavin metabolism:Pantothenate and CoA biosynthesis:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:Signal transduction mechanisms:TIGR00089:iojap_ybeB:ribD_Cterm:TIGR00302:aroE:ogt:2A51:rnd:histidine_hisI:Defense mechanisms:General:Unknown function:Anions:Transport and binding proteins:RNA processing:Transcription:DNA replication, recombination, and repair:DNA metabolism:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Amino acid biosynthesis:Aromatic amino acid family:Histidine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 108 "Chromatin structure and dynamics:Energy production and conversion:Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase:Pseudouridylate synthase:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Geranylgeranyl pyrophosphate synthase:Acetate kinase:Lactoylglutathione lyase and related lyases:Nitrogen regulatory protein PII:Enoyl-[acyl-carrier-protein] reductase (NADH):Ferredoxin:Predicted unusual protein kinase:FOG: CheY-like receiver:Deoxyxylulose-5-phosphate synthase:Phosphatidylserine synthase:Uncharacterized protein conserved in bacteria:Chorismate mutase:Integral membrane protein CcmA involved in cell shape determination:Exonuclease VII small subunit:Predicted membrane protein:Methylase involved in ubiquinone/menaquinone biosynthesis:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Arabinose efflux permease:Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism:Oligoketide cyclase/lipid transport protein:Signal transduction histidine kinase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Valine leucine and isoleucine degradation:Taurine and hypotaurine metabolism:Phosphonate and phosphinate metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Mismatch repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ackA:hisT_truA:dxs:phnA:TIGR00701:purE:xseB:MenG_MenH_UbiE:UbiB:UbiG:metmalonyl_epim:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Fermentation:Energy metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Replication and Repair:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Unknown function:Carbohydrate Metabolism:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone:Thiamine:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Conserved:Hypothetical proteins:tRNA and rRNA base modification:Protein synthesis:Degradation of DNA:DNA metabolism" 109 "Energy production and conversion:Adenylosuccinate lyase:Phenylalanyl-tRNA synthetase alpha subunit:Argininosuccinate synthase:Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase:Seryl-tRNA synthetase:Uncharacterized conserved protein:Ribosome recycling factor:Homoserine dehydrogenase:Phosphoribosylpyrophosphate synthetase:ATPase components of ABC transporters with duplicated ATPase domains:Threonine synthase:Aspartokinases:Uridylate kinase:FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor):Acetylglutamate kinase:Glycyl-tRNA synthetase, alpha subunit:Predicted sugar phosphate isomerase involved in capsule formation:3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase:Inorganic pyrophosphatase/exopolyphosphatase:Uncharacterized membrane protein, required for colicin V production:Lysyl-tRNA synthetase (class I):ATP sulfurylase (sulfate adenylyltransferase):Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose phosphate pathway:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Selenocompound metabolism:Vitamin B6 metabolism:Sulfur metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:argG:tig:thrC:sopT:glyQ:kpsF:serS:lysS_arch:pheS:frr:asp_kin_monofn:argB:purB:TIGR01033:ribP_PPkin:bisphos_cysQ:pyrH_bact:ABC_ABC_ChvD:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Central intermediary metabolism:Sulfur metabolism:Energy metabolism:Sugars:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Purine ribonucleotide biosynthesis:Regulatory functions:DNA interactions:Protein synthesis:tRNA aminoacylation:Translation factors:Protein fate:Protein folding and stabilization:Amino acid biosynthesis:Aspartate family:Glutamate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 110 "Purine nucleoside phosphorylase:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Glutamine synthetase:Predicted EndoIII-related endonuclease:Superfamily II DNA helicase:Sugar kinases, ribokinase family:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Single-stranded DNA-specific exonuclease:Predicted phosphatase/phosphohexomutase:Glycine/D-amino acid oxidases (deaminating):ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Outer membrane protein:ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains):Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Predicted phosphosugar isomerases:Predicted acetyltransferase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein related to deoxyribodipyrimidine photolyase:Signal transduction histidine kinase:Uncharacterized protein conserved in bacteria:Response regulator:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Amino sugar and nucleotide sugar metabolism:Nicotinate and nicotinamide metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:RNA degradation:Base excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:recQ_fam:recJ:nth:agmatinase:HAD-SF-IA-v3:PNPH-PUNA-XAPA:chp_TIGR02217:addA_alphas:Prophage functions:Mobile and extrachromosomal element functions:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function" 111 "Dihydroorotase and related cyclic amidohydrolases:Phosphoglycerate dehydrogenase and related dehydrogenases:Putative translation initiation inhibitor, yjgF family:Predicted amidohydrolase:Aspartate/tyrosine/aromatic aminotransferase:Transcriptional regulator:Demethylmenaquinone methyltransferase:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Cation/multidrug efflux pump:Membrane-fusion protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type polar amino acid transport system, ATPase component:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:Hydantoin racemase:ABC-type arginine transport system, permease component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Fatty acid biosynthesis:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:beta-Alanine metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Carbon fixation in photosynthetic organisms:Pantothenate and CoA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:HEQRo_perm_3TM:RND_mfp:D-hydantoinase:Defense mechanisms:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Metabolism:Lipid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Amino acids, peptides and amines:Unknown substrate:Transport and binding proteins:Metabolism:Global:Biosynthesis of Other Secondary Metabolites" 112 "Energy production and conversion:Cysteine synthase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Carbonic anhydrase:Ferredoxin:Integral membrane protein, interacts with FtsH:Membrane carboxypeptidase (penicillin-binding protein):Nitroreductase:FOG: CheY-like receiver:7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase:Transcriptional regulators, similar to M. xanthus CarD:Uncharacterized conserved protein:Transcriptional regulators:Uncharacterized proteins, homologs of lactam utilization protein B:Citrate lyase beta subunit:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:TRAP-type uncharacterized transport system, fused permease components:Uncharacterized conserved protein:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Site-specific recombinase XerC:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:Selenocompound metabolism:D-Arginine and D-ornithine metabolism:D-Alanine metabolism:Glyoxylate and dicarboxylate metabolism:Pantothenate and CoA biosynthesis:Folate biosynthesis:Porphyrin and chlorophyll metabolism:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:ilvE_I:folK:PBP_1a_fam:TRAP_fused:BluB:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyruvate family:Amino acid biosynthesis:Unknown substrate:Transport and binding proteins:Metabolism:Global:Metabolism" 113 "Energy production and conversion:Lipoprotein signal peptidase:NADPH:quinone reductase and related Zn-dependent oxidoreductases:3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:N-acetylmuramoyl-L-alanine amidase:Predicted branched-chain amino acid permease (azaleucine resistance):Putative periplasmic protein kinase ArgK and related GTPases of G3E family:Amino acid transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Fatty acid biosynthesis:Metabolic pathways:Protein export:General function prediction only:lspA:lao:fabZ:oxido_YhdH:Intracellular trafficking, secretion, and vesicular transport:Protein and peptide secretion and trafficking:Lipid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Regulatory functions:Protein interactions:Protein fate:Metabolism:Unknown function:Enzymes of unknown specificity:Cellular processes and signaling:Metabolism:Poorly characterized" 114 "Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Glutamine synthetase:Molybdopterin biosynthesis enzyme:Cytosine deaminase and related metal-dependent hydrolases:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Universal stress protein UspA and related nucleotide-binding proteins:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type dipeptide transport system, periplasmic component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Uncharacterized ABC-type transport system, permease component:ABC-type spermidine/putrescine transport system, permease component I:Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Glycosyltransferases, probably involved in cell wall biogenesis:Predicted glycosyltransferases:GTPases:Uncharacterized protein involved in exopolysaccharide biosynthesis:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:ABC-type arginine/histidine transport system, permease component:ABC-type arginine transport system, permease component:ABC-type histidine transport system, ATPase component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:G1P_cyt_trans:GTP_HflX:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:General:Unknown function:Poorly characterized:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism" 115 "Energy production and conversion:ABC-type sugar transport system, permease component:ADP-glucose pyrophosphorylase:Glycerol kinase:Glycerol-3-phosphate dehydrogenase:Sugar phosphate isomerases/epimerases:ABC-type multidrug transport system, ATPase and permease components:ABC-type sugar transport systems, permease components:ABC-type Fe3+ transport system, permease component:Alcohol dehydrogenase, class IV:Type II secretory pathway, pullulanase PulA and related glycosidases:ABC-type sugar transport system, periplasmic component:ABC-type maltose transport systems, permease component:ABC-type sugar transport systems, ATPase components:Predicted small integral membrane protein:Carbohydrate transport and metabolism:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Bisphenol degradation:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Function unknown:glycerol_kin:B_ant_repeat:glgX_debranch:MsbA_rel:Defense mechanisms:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Lipid Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Other:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism" 116 "Predicted Fe-S oxidoreductases:Predicted dehydrogenases and related proteins:MoxR-like ATPases:ABC-type multidrug transport system, permease component:ABC-type multidrug transport system, ATPase component:Mg-chelatase subunit ChlD:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):DNA-binding HTH domain-containing proteins:Nitric oxide reductase large subunit:Predicted membrane protein:Nitric oxide reductase activation protein:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:PQQ_syn_pqqE:TIGR02118:prismane_assoc:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Biosynthesis of Other Secondary Metabolites:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Hypothetical proteins:Conserved:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 117 "Superfamily I DNA and RNA helicases:dGTP triphosphohydrolase:Uncharacterized conserved protein:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Adenylate kinase and related kinases:Predicted unusual protein kinase:Membrane-fusion protein:Predicted membrane protein:DNA-binding HTH domain-containing proteins:Nucleotide transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Purine metabolism:Pyruvate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Nucleotide excision repair:Mismatch repair:General function prediction only:Function unknown:TIGR00049:yihY_not_rbn:adk:dGTP_triPase:RND_mfp:Ac_CoA_lig_AcsA:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Unknown substrate:Transport and binding proteins:Nucleotide and nucleoside interconversions:Metabolism:Global:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Replication and Repair:Genetic Information Processing:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism" 118 "Energy production and conversion:Rieske Fe-S protein:Lactate dehydrogenase and related dehydrogenases:Cytochrome b subunit of the bc complex:D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4):Acyl dehydratase:Bacterioferritin (cytochrome b1):Cytochrome c1:Poly(3-hydroxyalkanoate) synthetase:Signal transduction histidine kinase, glucose-6-phosphate specific:Signal transduction histidine kinase:Predicted membrane protein:Membrane-bound metallopeptidase:Uncharacterized conserved small protein:Cell cycle control, cell division, chromosome partitioning:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Oxidative phosphorylation:Bisphenol degradation:Peptidoglycan biosynthesis:Chloroalkane and chloroalkene degradation:Glyoxylate and dicarboxylate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:PBP4:bfr:TAT_signal_seq:PHA_synth_I:Xenobiotics Biodegradation and Metabolism:Glycan Biosynthesis and Metabolism:Energy Metabolism:Biosynthesis:Carbohydrate Metabolism:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Cations and iron carrying compounds:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cellular processes and signaling:Metabolism:Poorly characterized:Fatty acid and phospholipid metabolism:Metabolism:Global:Metabolism" 119 "Serine/threonine protein kinase:ATPases with chaperone activity, ATP-binding subunit:Serine/threonine protein phosphatase:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Hemolysin-coregulated protein (uncharacterized):Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein, contains FHA domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:vgr_GE:VI_ClpV1:VI_chp_1:VI_IcmF:IV_VI_DotU:VI_chp_3:VI_chp_4:VI_FHA:VI_chp_2:VI_zyme:VI_chp_5:VI_chp_6:Membrane Transport:Poorly characterized:Cellular processes and signaling:Information storage and processing:Pathogenesis:Cellular processes:Environmental Information Processing" 120 "Energy production and conversion:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs:Predicted phosphohydrolases:Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase:Transcriptional regulators:ABC-type sugar transport systems, ATPase components:Glucose dehydrogenase:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Pentose phosphate pathway:Fructose and mannose metabolism:Purine metabolism:Bisphenol degradation:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:PQQ_membr_DH:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Nucleotide Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Information storage and processing:Metabolism" 121 "Energy production and conversion:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Predicted methyltransferases:Isocitrate/isopropylmalate dehydrogenase:Phosphatidylglycerophosphate synthase:Uncharacterized membrane-associated protein:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Glutamine synthetase adenylyltransferase:Uncharacterized conserved protein:Uncharacterized conserved protein:Formyltetrahydrofolate synthetase:Uncharacterized conserved protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:ABC-type uncharacterized transport system, periplasmic component:ABC-type uncharacterized transport system, permease component:ABC-type thiamine transport system, periplasmic component:Acetyl/propionyl-CoA carboxylase, alpha subunit:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00096:leuB:sfuA:Pyruvate family:Amino acid biosynthesis:Enzymes of unknown specificity:Unknown function:Other:Transport and binding proteins:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism:Global:Poorly characterized:Signal Transduction:Metabolism:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 122 "Energy production and conversion:ABC-type sugar transport system, permease component:Glycerol kinase:Glycerol-3-phosphate dehydrogenase:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Panthothenate kinase:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:ABC-type sugar transport systems, permease components:Alcohol dehydrogenase, class IV:ABC-type sugar transport system, periplasmic component:ABC-type sugar transport system, periplasmic component:Transcriptional regulator/sugar kinase:ABC-type sugar transport systems, ATPase components:Predicted small integral membrane protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Bisphenol degradation:Glycerolipid metabolism:Glycerophospholipid metabolism:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Function unknown:glycerol_kin:Information storage and processing:Other:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling" 123 "Energy production and conversion:Uncharacterized conserved protein:ABC-type transport system involved in Fe-S cluster assembly, ATPase component:Selenocysteine lyase:Isocitrate dehydrogenases:Amino acid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Citrate cycle (TCA cycle):Selenocompound metabolism:Glutathione metabolism:Carbon fixation pathways in prokaryotes:Thiamine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:nadp_idh_euk:sufC:sufS:TCA cycle:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Energy Metabolism:Energy metabolism:Carbohydrate Metabolism" 124 "Energy production and conversion:tRNA and rRNA cytosine-C5-methylases:Glycosidases:Orotate phosphoribosyltransferase:Multimeric flavodoxin WrbA:Putative intracellular protease/amidase:Catalase:Formyltetrahydrofolate hydrolase:Flagellar hook-associated protein:Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs:Transcriptional regulators of sugar metabolism:Predicted redox protein, regulator of disulfide bond formation:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Uncharacterized protein containing a von Willebrand factor type A (vWA) domain:Predicted membrane protein:Uncharacterized conserved protein:Uncharacterized metal-binding protein:Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Galactose metabolism:Purine metabolism:Pyrimidine metabolism:Tryptophan metabolism:Starch and sucrose metabolism:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Flagellar assembly:General function prediction only:Function unknown:PurU:PfpI:flgK_ends:formald_GSH:osmo_induc_OsmC:Degradation of proteins, peptides, and glycopeptides:Protein fate:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:One-carbon metabolism:Central intermediary metabolism:Metabolism:Global:Metabolism:Cell Motility:Cellular Processes:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:Information storage and processing:Chemotaxis and motility:Detoxification:Cellular processes" 125 "Signal transduction histidine kinase:Mannose-1-phosphate guanylyltransferase:HrpA-like helicases:Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component:Predicted secreted hydrolase:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Fructose and mannose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:GMP_PMI:DEAH_box_HrpB:Information storage and processing:Carbohydrate Metabolism:Global:Metabolism:Unknown function:Enzymes of unknown specificity:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 126 "Chromatin structure and dynamics:Energy production and conversion:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:FAD/FMN-containing dehydrogenases:Cytosine deaminase and related metal-dependent hydrolases:Predicted transcriptional regulators:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Predicted permeases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Chromosome segregation ATPases:2'-5' RNA ligase:Transcriptional regulators:Transcriptional regulators:Inosine-uridine nucleoside N-ribohydrolase:FOG: GGDEF domain:Uncharacterized protein conserved in bacteria:Predicted permeases:Transposase and inactivated derivatives:Predicted acetyltransferase:Uncharacterized conserved protein:2-keto-3-deoxy-galactonokinase:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Galactose metabolism:Purine metabolism:Nicotinate and nicotinamide metabolism:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:SMC_prok_B:2_5_ligase:guan_deamin:Signal transduction:RNA processing:Transcription:Chromosome-associated proteins:DNA metabolism:Other:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Other" 127 "Energy production and conversion:Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Ribose 5-phosphate isomerase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:FAD/FMN-containing dehydrogenases:23S rRNA methylase:Riboflavin synthase alpha chain:Nucleoside-diphosphate-sugar epimerases:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:Exoribonuclease R:ABC-type cobalt transport system, permease component CbiQ and related transporters:Glycine/D-amino acid oxidases (deaminating):Bacterial nucleoid DNA-binding protein:Predicted permeases:Glutamate racemase:UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase:ABC-type spermidine/putrescine transport system, permease component I:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Transcriptional regulator:Uracil-DNA glycosylase:Putative transcriptional regulator:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose phosphate pathway:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:D-Glutamine and D-glutamate metabolism:Lipopolysaccharide biosynthesis:Pyruvate metabolism:Carbon fixation in photosynthetic organisms:Riboflavin metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:RNA degradation:General function prediction only:Function unknown:rpiA:TIGR00046:ribE:3_prime_RNase:UDG_fam4:himA:potA:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Riboflavin, FMN, and FAD:Biosynthesis of cofactors, prosthetic groups, and carriers:Amino acids, peptides and amines:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:Degradation of RNA:Transcription:DNA replication, recombination, and repair:DNA metabolism:Pentose phosphate pathway:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 128 "Transcription elongation factor:Uncharacterized conserved protein:Transcription:Function unknown:Information storage and processing:Poorly characterized" 129 "Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:N-methylhydantoinase A/acetone carboxylase, beta subunit:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Fatty acid metabolism:Phenylalanine metabolism:Folate biosynthesis:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:pabB:Folic acid:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Metabolism:Poorly characterized" 130 "Glutamate-1-semialdehyde aminotransferase:Undecaprenyl pyrophosphate synthase:Predicted GTPase:dGTP triphosphohydrolase:Site-specific DNA methylase:Folylpolyglutamate synthase:Guanosine polyphosphate pyrophosphohydrolases/synthetases:Di- and tricarboxylate transporters:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:CDP-diglyceride synthetase:Predicted permeases:Polyphosphate kinase:UDP-glucose 4-epimerase:ABC-type transport system involved in resistance to organic solvents, ATPase component:ABC-type (unclassified) transport system, ATPase component:Chorismate mutase:Predicted hydrolases of HD superfamily:Pyridoxal phosphate biosynthesis protein:Predicted ATPase (AAA+ superfamily):Uncharacterized Fe-S protein:ABC-type uncharacterized transport system, permease component:ABC-type branched-chain amino acid transport system, permease component:ABC-type uncharacterized transport system, permease component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Galactose metabolism:Oxidative phosphorylation:Purine metabolism:Cysteine and methionine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Glycerophospholipid metabolism:Vitamin B6 metabolism:Folate biosynthesis:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:RNA degradation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:uppS:pdxA:dcm:spoT_relA:galE:dGTP_triPase:folC:CM_mono_cladeE:GTPase_YsxC:poly_P_kin:Cellular processes and signaling:Metabolism:Poorly characterized:DNA metabolism:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Sugars:Energy metabolism:Phosphorus compounds:Central intermediary metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Folding Sorting and Degradation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:DNA replication, recombination, and repair:Carbohydrate Metabolism:Protein synthesis:Other:Cellular processes:Adaptations to atypical conditions:Amino acid biosynthesis:Aromatic amino acid family:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Pyridoxine:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing" 131 "Energy production and conversion:Polyprenyltransferase (cytochrome oxidase assembly factor):Coproporphyrinogen III oxidase:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Cytochrome oxidase assembly factor:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Bacteriophage head-tail adaptor:Coenzyme transport and metabolism:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Ribosome:General function prediction only:Function unknown:cyoE_ctaB:gp16_SPP1:CoxB:Mobile and extrachromosomal element functions:Energy Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Electron transport:Metabolism:Prophage functions:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Cellular processes and signaling:Metabolism:Poorly characterized" 132 "Energy production and conversion:Pentose-5-phosphate-3-epimerase:Molecular chaperone (small heat shock protein):Molecular chaperone:Zn-dependent protease with chaperone function:ATPases with chaperone activity, ATP-binding subunit:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Signal transduction histidine kinase:Exonuclease III:UDP-glucose pyrophosphorylase:ATP-dependent protease HslVU (ClpYQ), ATPase subunit:Disulfide bond chaperones of the HSP33 family:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:NADH:flavin oxidoreductases, Old Yellow Enzyme family:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Molybdenum cofactor biosynthesis enzyme:Uncharacterized protein conserved in bacteria:ATP-dependent protease HslVU (ClpYQ), peptidase subunit:Uncharacterized small protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pentose phosphate pathway:Pentose and glucuronate interconversions:Galactose metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Nitrotoluene degradation:Carbon fixation in photosynthetic organisms:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:RNA polymerase:Base excision repair:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:exoDNase_III:hslU:galU:rpe:prok_dnaK:moaA:quinone_pig3:sigma70-ECF:chaperone_ClpB:oxido_grp_1:ATP_dep_HslV:Metabolism:Carbohydrate Metabolism:Energy Metabolism:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Transcription:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Energy metabolism:Pentose phosphate pathway:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein folding and stabilization:Degradation of proteins, peptides, and glycopeptides:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 133 "Energy production and conversion:Nucleotidyltransferase/DNA polymerase involved in DNA repair:Glycosyltransferase:Putative GTPases (G3E family):Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:Membrane-fusion protein:Ni,Fe-hydrogenase I small subunit:Homoserine trans-succinylase:Uncharacterized protein conserved in bacteria:Predicted permeases:Uncharacterized protein conserved in bacteria:Predicted proteasome-type protease:ABC-type uncharacterized transport system, permease component:Arginine degradation protein (predicted deacylase):Predicted permease, DMT superfamily:Amino acid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Cysteine and methionine metabolism:Methane metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:rarD:metA:primase_Cterm:RND_mfp:Information storage and processing:Aspartate family:Amino acid biosynthesis:Prophage functions:Mobile and extrachromosomal element functions:Unknown substrate:Transport and binding proteins:Metabolism:Metabolism:Global:Amino Acid Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling" 134 "Energy production and conversion:Excinuclease ATPase subunit:Peptide methionine sulfoxide reductase:Conserved domain frequently associated with peptide methionine sulfoxide reductase:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Membrane protease subunits, stomatin/prohibitin homologs:Uncharacterized conserved protein:Ca2+/Na+ antiporter:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Lysophospholipase L1 and related esterases:Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component:Metal-dependent hydrolase:Predicted aspartyl protease:Predicted periplasmic protein:Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component:Uncharacterized conserved protein:Amino acid transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Nucleotide excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00357:TIGR00367:msrA:uvra:hflK:degP_htrA_DO:clan_AA_DTGA:Poorly characterized:Lipid Metabolism:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Replication and Repair:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Degradation of proteins, peptides, and glycopeptides:Cellular processes:Adaptations to atypical conditions:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 135 "Energy production and conversion:ABC-type branched-chain amino acid transport systems, ATPase component:ABC-type branched-chain amino acid transport systems, ATPase component:Sugar kinases, ribokinase family:Branched-chain amino acid ABC-type transport system, permease components:Methionine synthase I (cobalamin-dependent), methyltransferase domain:ABC-type branched-chain amino acid transport systems, periplasmic component:NAD-dependent aldehyde dehydrogenases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type sugar transport system, ATPase component:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Methionine synthase I, cobalamin-binding domain:Coenzyme F390 synthetase:ABC-type sugar transport system, periplasmic component:Arabinose efflux permease:Predicted ABC-type sugar transport system, permease component:ABC-type branched-chain amino acid transport system, permease component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Phenylalanine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:One carbon pool by folate:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:metH:Metabolism of Terpenoids and Polyketides:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Membrane Transport:Metabolism of Other Amino Acids:Poorly characterized:Metabolism:Aspartate family:Metabolism:Amino Acid Metabolism:Amino acid biosynthesis:Lipid Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Carbohydrate Metabolism" 136 "Glycine/D-amino acid oxidases (deaminating):Amidases related to nicotinamidase:Ketopantoate reductase:2-keto-3-deoxy-galactonokinase:ABC-type uncharacterized transport system, periplasmic component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Galactose metabolism:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Poorly characterized:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Metabolism:Metabolism" 137 "Energy production and conversion:Anaerobic dehydrogenases, typically selenocysteine-containing:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Glycosyltransferase:Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Uncharacterized conserved protein:Multidrug resistance efflux pump:Predicted membrane protein:Response regulator containing a CheY-like receiver domain and a GGDEF domain:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase:Protein involved in meta-pathway of phenol degradation:Uncharacterized protein conserved in bacteria:Phage-related protein:Signal transduction histidine kinase:Carbohydrate transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Chlorocyclohexane and chlorobenzene degradation:Benzoate degradation:Xylene degradation:Glyoxylate and dicarboxylate metabolism:Styrene degradation:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:dprA:portal_HK97:Fdhalpha-like:type_I_hlyD:Ku_bact:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Signal transduction:Carbohydrate Metabolism:Energy Metabolism:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein and peptide secretion and trafficking:Cellular processes:DNA transformation:Mobile and extrachromosomal element functions:Prophage functions:Metabolism:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 138 "Energy production and conversion:Uncharacterized membrane-associated protein:NADPH:quinone reductase and related Zn-dependent oxidoreductases:ABC-type Fe3+-siderophore transport system, permease component:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Methyl-accepting chemotaxis protein:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Glycosyltransferases, probably involved in cell wall biogenesis:Uncharacterized membrane protein:DNA repair proteins:Glucose/sorbosone dehydrogenases:Phage head maturation protease:Bacteriophage head-tail adaptor:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Bisphenol degradation:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:radc:proheadase_HK97:gp16_SPP1:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:Information storage and processing:Prophage functions:Mobile and extrachromosomal element functions:Other:Protein fate" 139 "Porphobilinogen deaminase:Uroporphyrinogen-III decarboxylase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Putative protein-S-isoprenylcysteine methyltransferase:Uncharacterized enzyme involved in pigment biosynthesis:Uncharacterized protein involved in response to NO:Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains:Putative heme degradation protein:Uncharacterized protein conserved in bacteria:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:hemC:hemE:nifA:rpoN_sigma:bchO_mg_che_rel:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Transcription:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Photosynthesis:Regulatory functions:DNA interactions:Transcription:Transcription factors:Metabolism:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 140 "cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Spermidine/putrescine-binding periplasmic protein:Cold shock proteins:Uncharacterized conserved protein:Acyl-CoA dehydrogenases:Acyl dehydratase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Glyoxylate and dicarboxylate metabolism:Microbial metabolism in diverse environments:Function unknown:Signal transduction mechanisms:fdxN_nitrog:Poorly characterized:Carbohydrate Metabolism:Global:Metabolism:Central intermediary metabolism:Nitrogen fixation:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 141 "Energy production and conversion:Ammonia permease:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Serine acetyltransferase:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:ATPases involved in chromosome partitioning:Uncharacterized membrane protein:DNA polymerase III, delta subunit:TRAP-type C4-dicarboxylate transport system, periplasmic component:Transcriptional regulator/sugar kinase:Putative NADPH-quinone reductase (modulator of drug activity B):Predicted acetamidase/formamidase:Predicted acyl esterases:TRAP-type C4-dicarboxylate transport system, small permease component:Uncharacterized protein conserved in bacteria:TRAP-type mannitol/chloroaromatic compound transport system, large permease component:Nitrogen fixation protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Purine metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Nitrogen metabolism:Sulfur metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Microbial metabolism in diverse environments:DNA replication:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:dctM:amt:/NonD:nifT_nitrog:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Enzymes of unknown specificity:Unknown function:Cations and iron carrying compounds:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism" 142 "Peptidyl-tRNA hydrolase:Predicted phosphatase/phosphohexomutase:Peroxiredoxin:N6-adenine-specific methylase:Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides:Bacteriophage head-tail adaptor:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Fatty acid metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Microbial metabolism in diverse environments:General function prediction only:TIGR00095:pth:HAD-SF-IA-v3:Protein synthesis:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Metabolism:Other:tRNA and rRNA base modification:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Poorly characterized" 143 "Energy production and conversion:Dihydroorotase and related cyclic amidohydrolases:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Acetyl-CoA acetyltransferase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Predicted amidohydrolase:Uncharacterized NAD(FAD)-dependent dehydrogenases:Transcriptional regulator:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:NAD-dependent aldehyde dehydrogenases:ABC-type polar amino acid transport system, ATPase component:Phytoene dehydrogenase and related proteins:3-hydroxyacyl-CoA dehydrogenase:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:Predicted metal-dependent hydrolase of the TIM-barrel fold:Hydantoin racemase:ABC-type arginine transport system, permease component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Fatty acid metabolism:Pyrimidine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Arginine and proline metabolism:Benzoate degradation:beta-Alanine metabolism:alpha-Linolenic acid metabolism:Ethylbenzene degradation:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:HEQRo_perm_3TM:AcCoA-C-Actrans:D-hydantoinase:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Metabolism:Energy Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Amino acids, peptides and amines:Transport and binding proteins:Other:Fatty acid and phospholipid metabolism:Metabolism" 144 "Energy production and conversion:Nucleoside-diphosphate-sugar epimerases:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Sulfate permease and related transporters (MFS superfamily):ATPase components of various ABC-type transport systems, contain duplicated ATPase:Deoxyxylulose-5-phosphate synthase:Multidrug resistance efflux pump:Predicted acyltransferases:Cation transport ATPase:Uncharacterized protein conserved in bacteria:Cytochrome B561:Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog):Uncharacterized membrane-bound protein:Uncharacterized membrane-anchored protein conserved in bacteria:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid metabolism:Polycyclic aromatic hydrocarbon degradation:Naphthalene degradation:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:dxs:ATPase_P-type:cbbX_cfxQ:Defense mechanisms:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 145 "Uncharacterized ABC-type transport system, permease component:Threonine dehydratase:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family:ABC-type uncharacterized transport systems, ATPase components:ABC-type uncharacterized transport system, permease component:Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A:Xanthine dehydrogenase, molybdopterin-binding subunit B:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:xanthine_xdhA:xanthine_xdhC:Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Other:Cellular processes and signaling:Metabolism:Poorly characterized" 146 "Molecular chaperone:Signal transduction histidine kinase:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Flagellar biosynthesis pathway, component FliR:Threonine aldolase:AraC-type DNA-binding domain-containing proteins:Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component:Uncharacterized protein conserved in bacteria:Predicted ester cyclase:Uncharacterized conserved protein:Predicted secreted hydrolase:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Global:Metabolism:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing" 147 "3-oxoacyl-(acyl-carrier-protein) synthase:Nucleoside-diphosphate-sugar epimerases:Branched-chain amino acid ABC-type transport system, permease components:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:UDP-glucose 4-epimerase:Glycosyltransferases, probably involved in cell wall biogenesis:Flagellar motor component:Flagellar biosynthesis pathway, component FliP:Flagellar basal body-associated protein:Flagellar biosynthesis/type III secretory pathway lipoprotein:Site-specific recombinases, DNA invertase Pin homologs:Uncharacterized conserved protein:Beta-mannanase:Phage DNA packaging protein, Nu1 subunit of terminase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Galactose metabolism:Fatty acid biosynthesis:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Bacterial chemotaxis:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Signal transduction mechanisms:fliF:fliP:galE:urea_trans_UrtB:MotA1:Intracellular trafficking, secretion, and vesicular transport:Cellular processes:Amino acids, peptides and amines:Transport and binding proteins:Sugars:Energy metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Lipid Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Chemotaxis and motility" 148 "Energy production and conversion:Fe-S oxidoreductase:FAD/FMN-containing dehydrogenases:Sugar kinases, ribokinase family:Oligoendopeptidase F:L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:Glucose/sorbosone dehydrogenases:Transcriptional regulators:Malate synthase:Cytochrome c553:V8-like Glu-specific endopeptidase:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:malate_syn_G:M3_fam_3:Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:TCA cycle:Energy metabolism:Metabolism:Global:Carbohydrate Metabolism:Metabolism" 149 "Energy production and conversion:Putative translation factor (SUA5):Glutamine amidotransferase:Glycerol-3-phosphate dehydrogenase:Thioredoxin reductase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Thiol-disulfide isomerase and thioredoxins:Predicted permease:Glutathionylspermidine synthase:ABC-type transport system involved in cytochrome c biogenesis, permease component:Ribosome-binding factor A:Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type):Membrane-bound lytic murein transglycosylase B:Predicted periplasmic protein:ABC-type transport system involved in cytochrome c biogenesis, ATPase component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pyrimidine metabolism:Histidine metabolism:Glycerophospholipid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Phosphotransferase system (PTS):General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00057:rbfA:dsbE:ccmA:ccmC:TRX_reduct:IMP_synth_hisH:cytochro_ccmD:Poorly characterized:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Transcription:RNA processing:Protein fate:Protein folding and stabilization:Transport and binding proteins:Other:Unknown function:General:Amino acid biosynthesis:Histidine family:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 150 "Pyruvate kinase:ATPase components of ABC transporters with duplicated ATPase domains:Transcriptional regulator:Putative intracellular protease/amidase:Methyl-accepting chemotaxis protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted amidophosphoribosyltransferases:Sugar phosphate isomerases/epimerases:L-serine deaminase:DNA repair proteins:Cu/Zn superoxide dismutase:Topoisomerase IB:DNA G:T-mismatch repair endonuclease:Bacteriophage tail assembly protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Purine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Inositol phosphate metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Carbon fixation in photosynthetic organisms:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:radc:vsr:sda_mono:PfpI:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Degradation of proteins, peptides, and glycopeptides:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 151 "Ribosomal protein L14:Ribosomal protein L5:Ribosomal protein S8:Ribosomal protein L6P/L9E:Ribosomal protein S13:Ribosomal protein S11:Ribosomal protein L13:Ribosomal protein S9:Ribosomal protein L24:Ribosomal protein S14:DNA-directed RNA polymerase, alpha subunit/40 kD subunit:Ribosomal protein L17:Ribosomal protein L18:Translation, ribosomal structure and biogenesis:Transcription:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:Ribosome:RNA polymerase:L17:L18_bact:rplM_bact:rplN_bact:rplX_bact:rpoA:bact_S13:bact_S11:L6_bact:Information storage and processing:Ribosomal proteins: synthesis and modification:Protein synthesis:DNA-dependent RNA polymerase:Transcription:Metabolism:Metabolism:Global:Translation:Transcription:Genetic Information Processing:Nucleotide Metabolism" 152 "Helicase subunit of the DNA excision repair complex:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Uncharacterized conserved protein:Threonine aldolase:Predicted flavoproteins:Uncharacterized protein with SCP/PR1 domains:Predicted enzyme of the cupin superfamily:Signal transduction histidine kinase, nitrogen specific:Uncharacterized protein containing double-stranded beta helix domain:Predicted membrane protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Replication, recombination and repair:Glycine serine and threonine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Nucleotide excision repair:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00275:uvrb:Cellular processes and signaling:Amino Acid Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Unknown function:Enzymes of unknown specificity:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 153 "Deoxyribodipyrimidine photolyase:Serine/threonine protein phosphatase:MoxR-like ATPases:Mannose-1-phosphate guanylyltransferase:Phosphomannomutase:Flagellar basal body rod protein:Flagellar hook-basal body protein:Flagellar basal body protein:Flagellar biosynthesis pathway, component FliQ:Flagellar basal body L-ring protein:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Predicted phage phi-C31 gp36 major capsid-like protein:Flagellar basal body rod protein:Carbohydrate transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Fructose and mannose metabolism:Amino sugar and nucleotide sugar metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Flagellar assembly:General function prediction only:Function unknown:Signal transduction mechanisms:GMP_PMI:vgr_GE:flgG_G_neg:flgF:flgA_cterm:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Carbohydrate Metabolism:Cellular Processes:Cell Motility:Global:Metabolism:Cellular processes:Chemotaxis and motility:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 154 "Molybdopterin converting factor, large subunit:Arsenate reductase and related proteins, glutaredoxin family:Molybdopterin converting factor, small subunit:Negative regulator of beta-lactamase expression:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Sulfur relay system:moaD:Defense mechanisms:Metabolism:Folding Sorting and Degradation:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Cellular processes and signaling:Genetic Information Processing" 155 "Energy production and conversion:ABC-type phosphate transport system, periplasmic component:Anaerobic dehydrogenases, typically selenocysteine-containing:Molybdopterin biosynthesis enzyme:ABC-type sugar transport system, permease component:ABC-type phosphate transport system, permease component:ABC-type phosphate transport system, permease component:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Phosphate uptake regulator:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type phosphate transport system, ATPase component:Transcriptional regulators of sugar metabolism:Pirin-related protein:Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit:Uncharacterized component of anaerobic dehydrogenases:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:ABC transporters:Two-component system:General function prediction only:Signal transduction mechanisms:bisC_fam:3a0107s01c2:3a0107s02c:B_ant_repeat:phoU_full:phosphate_pstC:PhoB:torC:Membrane Transport:Poorly characterized:Cellular processes and signaling:Information storage and processing:Two-component systems:Signal transduction:Environmental Information Processing:Anions:Transport and binding proteins:Signal Transduction:Metabolism" 156 "Energy production and conversion:Dihydroorotase and related cyclic amidohydrolases:Fumarase:Isopropylmalate/homocitrate/citramalate synthases:Protein chain release factor A:Glycine/D-amino acid oxidases (deaminating):Apolipoprotein N-acyltransferase:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Phytoene/squalene synthetase:Cyclopropane fatty acid synthase and related methyltransferases:Intracellular septation protein A:Membrane-bound lytic murein transglycosylase B:Ureidoglycolate hydrolase:Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Citrate cycle (TCA cycle):Purine metabolism:Pyrimidine metabolism:Valine leucine and isoleucine biosynthesis:beta-Alanine metabolism:Pyruvate metabolism:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:prfA:TIGR00093:lnt:LeuA_rel:fumC_II:D-hydantoinase:MltB_2:Cellular processes and signaling:Metabolism:Poorly characterized:Energy metabolism:Metabolism:Global:Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:TCA cycle:Carbohydrate Metabolism:Protein synthesis:tRNA and rRNA base modification:Translation factors:Protein fate:Protein modification and repair:Unknown function:General:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing" 157 "Energy production and conversion:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Asparagine synthase (glutamine-hydrolyzing):ABC-type dipeptide transport system, periplasmic component:Putative heme iron utilization protein:FOG: CheY-like receiver:Ribulose kinase:ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains):ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Transcriptional regulators:Transcriptional regulators:Predicted membrane-associated, metal-dependent hydrolase:Predicted acetamidase/formamidase:Uncharacterized protein conserved in bacteria:ABC-type thiamine transport system, ATPase component:ABC-type xylose transport system, periplasmic component:ABC-type xylose transport system, permease component:Short-chain alcohol dehydrogenase of unknown specificity:Site-specific recombinase XerC:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Styrene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:5C_CHO_kinase:addA_alphas:KdgD:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Xenobiotics Biodegradation and Metabolism" 158 "Energy production and conversion:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Signal transduction histidine kinase:Aldo/keto reductases, related to diketogulonate reductase:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Recombinational DNA repair ATPase (RecF pathway):Peroxiredoxin:Cobyric acid synthase:Putative hemolysin:Predicted enzyme of the cupin superfamily:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Ascorbate and aldarate metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Homologous recombination:General function prediction only:Signal transduction mechanisms:TIGR00052:cobQ:Poorly characterized:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Unknown function:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Replication and Repair:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Heme, porphyrin, and cobalamin:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism" 159 "Isopropylmalate/homocitrate/citramalate synthases:Histidinol dehydrogenase:Thymidylate synthase:Dihydrofolate reductase:DNA primase (bacterial type):Predicted amidohydrolase:Protein-tyrosine-phosphatase:Deoxyribodipyrimidine photolyase:Acetyltransferases:Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):2-methylthioadenine synthetase:dUTPase:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:ABC-type antimicrobial peptide transport system, ATPase component:Inactive homolog of metal-dependent proteases, putative molecular chaperone:Uncharacterized conserved protein:Phytoene/squalene synthetase:Cyclopropane fatty acid synthase and related methyltransferases:Methylase of polypeptide chain release factors:Ketosteroid isomerase-related protein:ABC-type transport system, involved in lipoprotein release, permease component:Membrane carboxypeptidase/penicillin-binding protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pyrimidine metabolism:Valine leucine and isoleucine biosynthesis:Histidine metabolism:Peptidoglycan biosynthesis:Pyruvate metabolism:One carbon pool by folate:Thiamine metabolism:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:RNA polymerase:DNA replication:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:hisD:TIGR00089:hemK_fam:dut:LeuA_rel:dnaG:PBP_1a_fam:TIGR02096:lolCE:RpoD_Cterm:thym_sym:bact_YeaZ:Defense mechanisms:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope:Histidine family:Amino acid biosynthesis:General:Unknown function:Protein modification and repair:Protein and peptide secretion and trafficking:Protein fate:Transcription factors:Transcription:DNA replication, recombination, and repair:DNA metabolism:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing" 160 "Arginyl-tRNA synthetase:ATP phosphoribosyltransferase:Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase:Isoleucyl-tRNA synthetase:Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase:Histidyl-tRNA synthetase:Phosphoribosylamine-glycine ligase:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Integral membrane protein possibly involved in chromosome condensation:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:ATPase components of ABC transporters with duplicated ATPase domains:Pseudouridylate synthases, 23S RNA-specific:Glycyl-tRNA synthetase, beta subunit:Glucokinase:Na+/H+ antiporter NhaD and related arsenite permeases:Choline-glycine betaine transporter:Predicted ATPase:Cytosine/uracil/thiamine/allantoin permeases:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Galactose metabolism:Purine metabolism:Valine leucine and isoleucine biosynthesis:Histidine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:rluA_subfam:TIGR00007:hisG:glyS:valS:hisS:argS:bcct:purD:parC_Gneg:purE:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Amino Acid Metabolism:Nucleotide Metabolism:tRNA and rRNA base modification:Carbohydrate Metabolism:Transport and binding proteins:Other:Amino acid biosynthesis:Histidine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:tRNA aminoacylation:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Purine ribonucleotide biosynthesis" 161 "Energy production and conversion:Predicted Zn-dependent proteases and their inactivated homologs:Uncharacterized conserved protein:Lipoate synthase:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Fe2+/Zn2+ uptake regulation proteins:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:ABC-type Mn2+/Zn2+ transport systems, permease components:ABC-type Mn/Zn transport systems, ATPase component:Predicted membrane protein, hemolysin III homolog:Uncharacterized conserved protein:Uncharacterized conserved protein:Predicted transcriptional regulator:Predicted glutamine amidotransferases:Predicted metal-sulfur cluster biosynthetic enzyme:Bacterioferritin (cytochrome b1):Secreted and surface protein containing fasciclin-like repeats:Predicted membrane protein:Predicted periplasmic or secreted protein:Predicted thiol oxidoreductase:Uncharacterized protein conserved in bacteria:Predicted symporter:ABC-type Zn2+ transport system, periplasmic component/surface adhesin:Phage-related protein:Site-specific recombinase XerD:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Thiamine metabolism:Lipoic acid metabolism:Metabolic pathways:ABC transporters:RNA polymerase:Sulfur relay system:General function prediction only:Function unknown:TIGR00049:lipA:rrf2_super:bfr:sss:portal_HK97:sigma70-ECF:SUF_assoc:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Prophage functions:Mobile and extrachromosomal element functions:Cations and iron carrying compounds:Transport and binding proteins:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Poorly characterized:Metabolism of Cofactors and Vitamins:Metabolism:Cellular processes and signaling:Information storage and processing:Lipoate:Other" 162 "Aspartate/tyrosine/aromatic aminotransferase:Molybdopterin biosynthesis enzymes:Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:Predicted transcriptional regulators:Predicted ATPase or kinase:Predicted hydrolase (HAD superfamily):Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities:Uncharacterized protein conserved in bacteria:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Putative transcriptional regulator:dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Phosphohistidine phosphatase SixA:Transcriptional regulators:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:N-formylglutamate amidohydrolase:Uncharacterized protein conserved in bacteria:ABC-type spermidine/putrescine transport systems, ATPase components:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Selenocompound metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Carbon fixation in photosynthetic organisms:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:HI0065_YjeE:molyb_syn:sensory_box:unchar_dom_1:potA:rmlC:Pyr-5-nucltdase:rpoN_sigma:Cellular processes and signaling:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Transcription:Folding Sorting and Degradation:Environmental Information Processing:Signal Transduction:Global:Metabolism:Regulatory functions:Small molecule interactions:Transcription:Transcription factors:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:Enzymes of unknown specificity:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 163 "Energy production and conversion:Porphobilinogen deaminase:Polyferredoxin:Uroporphyrinogen-III decarboxylase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Sulfate permease and related transporters (MFS superfamily):cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Putative heme iron utilization protein:NADH:ubiquinone oxidoreductase subunit 2 (chain N):Phytoene dehydrogenase and related proteins:Predicted transcriptional regulator:Putative protein-S-isoprenylcysteine methyltransferase:ATP:corrinoid adenosyltransferase:Nitrogenase molybdenum-iron protein, alpha and beta chains:Putative heme degradation protein:Uncharacterized membrane-anchored protein conserved in bacteria:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Oxidative phosphorylation:Porphyrin and chlorophyll metabolism:Carotenoid biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:hemC:cobA:rrf2_super:DPOR_bchN:hemE:AcsF:crtI_fam:photo_alph_chp2:bchO_mg_che_rel:Information storage and processing:Energy Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Global:Metabolism:Energy metabolism:Photosynthesis:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Heme, porphyrin, and cobalamin:Chlorophyll and bacteriochlorphyll:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 164 "Energy production and conversion:Ribonuclease HII:4-hydroxybenzoate polyprenyltransferase and related prenyltransferases:Methionine synthase I (cobalamin-dependent), methyltransferase domain:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:DNA polymerase I - 3'-5' exonuclease and polymerase domains:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Ubiquinone and other terpenoid-quinone biosynthesis:Purine metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:One carbon pool by folate:Metabolic pathways:Biosynthesis of secondary metabolites:Bacterial chemotaxis:Flagellar assembly:DNA replication:Base excision repair:Nucleotide excision repair:Homologous recombination:Function unknown:pola:ubiA_proteo:Ubi-OHases:Information storage and processing:Metabolism:Poorly characterized:Cellular Processes:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Global:Metabolism:Metabolism:Cell Motility:DNA metabolism:DNA replication, recombination, and repair:Biosynthesis of cofactors, prosthetic groups, and carriers:Menaquinone and ubiquinone" 165 "Phage tail tube protein FII:Carotenoid biosynthesis:Aminoacyl-tRNA biosynthesis:Ribosome:Protein export:General function prediction only:tail_tube:Poorly characterized:Folding Sorting and Degradation:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Translation:Metabolism:Mobile and extrachromosomal element functions:Prophage functions" 166 "Energy production and conversion:Predicted GTPase, probable translation factor:Transketolase:Malate/lactate dehydrogenases:Phenylalanyl-tRNA synthetase beta subunit:3-phosphoglycerate kinase:Aspartate-semialdehyde dehydrogenase:Argininosuccinate synthase:Aspartyl-tRNA synthetase:Putative translation initiation inhibitor, yjgF family:Short-chain dehydrogenases of various substrate specificities:Threonyl-tRNA synthetase:Prolyl-tRNA synthetase:Membrane GTPase LepA:GMP synthase, PP-ATPase domain/subunit:Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Predicted GTPases:Inorganic pyrophosphatase/exopolyphosphatase:Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins:FOG: WD40-like repeat:Ribosomal protein L25 (general stress protein Ctc):DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes:Peptide chain release factor RF-3:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Pentose phosphate pathway:Fructose and mannose metabolism:Fatty acid biosynthesis:Oxidative phosphorylation:Purine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Carbon fixation in photosynthetic organisms:Carbon fixation pathways in prokaryotes:Aminoacyl-tRNA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:argG:TIGR00092:small_GTP:tktlase_bact:glpX:thrS:aspS_bact:pheT_bact:ctc_TL5:guaA_Cterm:asd_B:MalateDH_bact:3oxo_ACP_reduc:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:Pentose phosphate pathway:TCA cycle:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Protein synthesis:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:Unknown function:General:Amino acid biosynthesis:Aspartate family:Glutamate family:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 167 "Uroporphyrinogen-III methylase:Putative GTPases (G3E family):ABC-type Fe3+-siderophore transport system, permease component:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Precorrin-3B methylase:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Cobyrinic acid a,c-diamide synthase:Uncharacterized conserved protein:Precorrin-6B methylase 1:Precorrin-2 methylase:Precorrin-4 methylase:Outer membrane cobalamin receptor protein:ABC-type hemin transport system, periplasmic component:Predicted metal-binding protein:Coenzyme transport and metabolism:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:cobB:cobM_cbiF:cobJ_cbiH:cobI_cbiL:cobA_cysG_Cterm:CobF:CbiE:CobW:Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Metabolism:Poorly characterized" 168 "Chromatin structure and dynamics:Energy production and conversion:Xaa-Pro aminopeptidase:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Phosphoglycerate dehydrogenase and related dehydrogenases:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Glycosyltransferase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Glycine/D-amino acid oxidases (deaminating):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Uncharacterized conserved protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Uncharacterized protein conserved in bacteria:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Serine phosphatase RsbU, regulator of sigma subunit:Molybdenum cofactor biosynthesis enzyme:Uncharacterized protein involved in response to NO:Uncharacterized protein conserved in bacteria:Uncharacterized protein containing caspase domain:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Oxidative phosphorylation:Glycine serine and threonine metabolism:Arginine and proline metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:RNA polymerase:Non-homologous end-joining:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:rocF_arginase:phge_HK97_gp10:hydantase:moaA:Ku_bact:sigma70-ECF:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Prophage functions:Mobile and extrachromosomal element functions:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Amino Acid Metabolism:Energy Metabolism" 169 "GTPases - translation elongation factors:Ribosomal protein S2:Ribosomal protein L11:Ribosomal protein L1:Ribosomal protein S13:Ribosomal protein S11:Ribosomal protein S15P/S13E:Transcription elongation factor:Ribosomal protein L27:Ribosomal protein S18:Ribosomal protein L10:Ribosomal protein L31:Ribosomal protein L21:Translation elongation factor Ts:Ribosomal protein L35:Ribosomal protein L20:Ribosomal protein L19:Ribosomal protein L9:Ribosomal protein S4 and related proteins:Translation initiation factor 2 (IF-2; GTPase):Uncharacterized protein conserved in bacteria:Translation, ribosomal structure and biogenesis:Transcription:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:Ribosome:RNA polymerase:Function unknown:rpmI_bact:L21:L27:L31:tsf:L9:S18:small_GTP:S15_bact:rpsB_bact:rpsD_bact:rplS_bact:rplT_bact:rplA_bact:L11_bact:NusA:rpoB:bact_S13:bact_S11:Transcription:Genetic Information Processing:Protein synthesis:Nucleotide Metabolism:Ribosomal proteins: synthesis and modification:Translation factors:Unknown function:General:Information storage and processing:Poorly characterized:Transcription factors:DNA-dependent RNA polymerase:Transcription:Metabolism:Metabolism:Global:Translation" 170 "Chromatin structure and dynamics:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Predicted amidohydrolase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Demethylmenaquinone methyltransferase:Spermidine/putrescine-binding periplasmic protein:ABC-type dipeptide transport system, periplasmic component:ATPase components of various ABC-type transport systems, contain duplicated ATPase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Inorganic ion transport and metabolism:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Aminobenzoate degradation:Styrene degradation:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Information storage and processing:Metabolism:Poorly characterized" 171 "Energy production and conversion:EMAP domain:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Pyrroline-5-carboxylate reductase:Uncharacterized NAD(FAD)-dependent dehydrogenases:Integrase:Transcriptional regulator:MoxR-like ATPases:Cation/multidrug efflux pump:Membrane-fusion protein:Lactate dehydrogenase and related dehydrogenases:Cobalamin biosynthesis protein CobD/CbiB:Putative threonine efflux protein:Transcriptional regulators:ABC-type sugar transport system, periplasmic component:Acyl-CoA dehydrogenases:Rhodanese-related sulfurtransferase:Putative hemolysin:Uncharacterized conserved protein:Sarcosine oxidase gamma subunit:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose phosphate pathway:Fatty acid metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Benzoate degradation:Tryptophan metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:D-Arginine and D-ornithine metabolism:D-Alanine metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Sulfur relay system:General function prediction only:Function unknown:proC:cobD:soxA:RND_mfp:TRAP_fused:chap_CsaA:Defense mechanisms:Glutamate family:Amino acid biosynthesis:Unknown substrate:Transport and binding proteins:Protein and peptide secretion and trafficking:Protein fate:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers" 172 "Energy production and conversion:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Fe2+ transport system protein B:Uncharacterized NAD(FAD)-dependent dehydrogenases:Integrase:Cytochrome bd-type quinol oxidase, subunit 1:Cytochrome bd-type quinol oxidase, subunit 2:Fe2+ transport system protein A:Predicted transcriptional regulator:Methylase involved in ubiquinone/menaquinone biosynthesis:N-acyl-D-glucosamine 2-epimerase:Sarcosine oxidase delta subunit:Sarcosine oxidase gamma subunit:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Oxidative phosphorylation:Glycine serine and threonine metabolism:Metabolic pathways:General function prediction only:cydB:small_GTP:rrf2_super:soxA:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Global:Metabolism:Energy metabolism:Amino acids and amines:Electron transport:Unknown function:General:Information storage and processing:Metabolism:Metabolism" 173 "Tryptophan synthase beta chain:Phosphoribosylanthranilate isomerase:1-acyl-sn-glycerol-3-phosphate acyltransferase:Lactoylglutathione lyase and related lyases:Recombinational DNA repair protein (RecF pathway):ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Uncharacterized protein conserved in bacteria:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Predicted membrane protein:Cell division protein:DNA polymerase III, gamma/tau subunits:Predicted ATPase involved in cell division:ABC-type oligopeptide transport system, periplasmic component:ABC-type uncharacterized transport system, duplicated ATPase component:Predicted secreted protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Glycerolipid metabolism:Glycerophospholipid metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Ribosome:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:DNA_YbaB_EbfC:trpB:recR:TIGR00701:MJ0042_CXXC:dnaX_nterm:metmalonyl_epim:Aromatic amino acid family:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Genetic Information Processing:Translation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Hypothetical proteins:Conserved:Unknown function:General:Amino acid biosynthesis:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 174 "Energy production and conversion:Trk-type K+ transport systems, membrane components:Acetyl-CoA acetyltransferase:1-acyl-sn-glycerol-3-phosphate acyltransferase:Gamma-glutamyltransferase:Predicted permease:Dehydrogenases (flavoproteins):Phosphopentomutase:Uncharacterized ABC-type transport system, permease component:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ABC-type spermidine/putrescine transport system, permease component II:3-hydroxyacyl-CoA dehydrogenase:Uncharacterized conserved protein:Predicted transcriptional regulator containing the HTH domain:Adenosine deaminase:GAF domain-containing protein:Electron transfer flavoprotein, alpha subunit:Electron transfer flavoprotein, beta subunit:Transcriptional regulators:FOG: GGDEF domain:Uncharacterized conserved protein:Putative hemolysin:Predicted phosphotransferase related to Ser/Thr protein kinases:Uncharacterized conserved protein:ABC-type uncharacterized transport systems, ATPase components:ABC-type uncharacterized transport system, permease component:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Pentose phosphate pathway:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Purine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:Glutathione metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Arachidonic acid metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Caprolactam degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:TIGR00281:aden_deam:deoB:AcCoA-C-Actrans:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Fatty acid and phospholipid metabolism:Other:Purines, pyrimidines, nucleosides, and nucleotides:Other:DNA metabolism:Chromosome-associated proteins:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Metabolism" 175 "Energy production and conversion:Phosphoglucomutase:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Putative translation initiation inhibitor, yjgF family:Leucyl aminopeptidase:Carbonic anhydrase:Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Glycerophosphoryl diester phosphodiesterase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):NADPH:quinone reductase and related Zn-dependent oxidoreductases:Alanine dehydrogenase:Urease accessory protein UreF:Lactate dehydrogenase and related dehydrogenases:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Threonine dehydratase:Beta-lactamase class C and other penicillin binding proteins:Cytochrome P450:Uncharacterized conserved protein:FOG: GGDEF domain:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Urease accessory protein UreE:DNA polymerase III, chi subunit:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Galactose metabolism:Fatty acid metabolism:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Lysine biosynthesis:Lysine degradation:Tryptophan metabolism:Taurine and hypotaurine metabolism:Glutathione metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Pyruvate metabolism:Aminobenzoate degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:DNA replication:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ureG:GGDEF:ahpD_dom:Defense mechanisms:Lipid Metabolism:Energy Metabolism:Nitrogen metabolism:Carbohydrate Metabolism:Unknown function:General:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Central intermediary metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism" 176 "Energy production and conversion:3-oxoacyl-(acyl-carrier-protein) synthase:Lactoylglutathione lyase and related lyases:Transcriptional regulator:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Glutathione S-transferase:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Diacylglycerol kinase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:ABC-type Na+ efflux pump, permease component:Transcriptional regulators:Uncharacterized conserved protein:Predicted membrane-associated, metal-dependent hydrolase:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:AraC-type DNA-binding domain-containing proteins:Nitrate/nitrite transporter:ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain:Uncharacterized protein conserved in bacteria:Acetolactate synthase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Glutathione metabolism:Glycerolipid metabolism:Inositol phosphate metabolism:Glycerophospholipid metabolism:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:Defense mechanisms:Carbohydrate Metabolism:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Lipid Metabolism" 177 "Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Predicted thioesterase:Transcriptional regulator:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Folate biosynthesis:General function prediction only:Function unknown:TIGR00051:pabB:Poorly characterized:Metabolism of Cofactors and Vitamins:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Information storage and processing:Metabolism:Metabolism" 178 "Protein chain release factor A:ATPases with chaperone activity, ATP-binding subunit:Glycine/D-amino acid oxidases (deaminating):ATPases involved in chromosome partitioning:3-hydroxyacyl-CoA dehydrogenase:Predicted Fe-S protein:Cytochrome c biogenesis factor:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Glycine serine and threonine metabolism:Phenylalanine metabolism:Benzoate degradation:Butanoate metabolism:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:prfA:soxB:ClpA:cytochro_ccmI:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Energy metabolism:Amino acids and amines:Electron transport:Protein synthesis:Translation factors:Protein fate:Degradation of proteins, peptides, and glycopeptides:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 179 "Flagellar motor component:Flagellar basal body-associated protein:Flagellar hook protein FlgE:Flagellar basal body protein:Flagellar motor switch protein:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Flagellar basal body rod protein:Cell wall/membrane/envelope biogenesis:Cell motility:Aminoacyl-tRNA biosynthesis:Two-component system:Bacterial chemotaxis:Flagellar assembly:FlgB:fliM_switch:FlgEFG_subfam:Cellular processes and signaling:Chemotaxis and motility:Cellular processes:Genetic Information Processing:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Translation" 180 "Uroporphyrinogen-III methylase:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:cobA_cysG_Cterm:gp16_SPP1:Metabolism:Mobile and extrachromosomal element functions:Prophage functions:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism:Metabolism of Cofactors and Vitamins" 181 "Chorismate synthase:Glutamine amidotransferase:Lipoate-protein ligase B:Zn-dependent protease with chaperone function:Pyridoxal phosphate biosynthesis protein:Arsenate reductase and related proteins, glutaredoxin family:Transcriptional regulators:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type):Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Cytochrome c-type biogenesis protein CcmE:Gamma-glutamylcysteine synthetase:Uncharacterized conserved protein:Kynureninase:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Histidine metabolism:Tryptophan metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glutathione metabolism:Vitamin B6 metabolism:Lipoic acid metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Phosphotransferase system (PTS):RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:aroC:lipB:pdxJ:glu_cys_lig_pln:kynureninase:IMP_synth_hisH:yccV:sigma70-ECF:Poorly characterized:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Transcription:Translation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:Amino acids and amines:Protein fate:Protein modification and repair:Amino acid biosynthesis:Aromatic amino acid family:Histidine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridoxine:Glutathione and analogs:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 182 "Mg-dependent DNase:Imidazoleglycerol-phosphate dehydratase:Tryptophan synthase beta chain:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Predicted metal-dependent hydrolase:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division:NAD/FAD-utilizing enzyme apparently involved in cell division:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:Predicted GTPase:RNase P protein component:Fe2+/Zn2+ uptake regulation proteins:Acetyl-CoA carboxylase alpha subunit:Transcription termination factor:ATPases involved in chromosome partitioning:Metal-dependent hydrolases of the beta-lactamase superfamily I:Predicted transcriptional regulators:Multidrug resistance efflux pump:Uncharacterized conserved protein:Membrane transporters of cations and cationic drugs:Surface lipoprotein:ABC-type transport system involved in resistance to organic solvents, auxiliary component:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:ABC-type protease/lipase transport system, ATPase and permease components:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Glycine serine and threonine metabolism:Lysine biosynthesis:Histidine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Streptomycin biosynthesis:Inositol phosphate metabolism:Pyruvate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:RNA degradation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00010:TIGR00043:gidA:gidB:parB_part:rnpA:small_GTP:trpB:accA:dapA:TIGR00697:rho:gyrA:DAHP_synth_II:type_I_sec_PrtD:type_I_hlyD:Defense mechanisms:Biosynthesis:Fatty acid and phospholipid metabolism:Transcription:Information storage and processing:Aspartate family:Aromatic amino acid family:Amino acid biosynthesis:General:Enzymes of unknown specificity:Unknown function:Conserved:Hypothetical proteins:Protein and peptide secretion and trafficking:Protein fate:tRNA and rRNA base modification:Other:Protein synthesis:Metabolism:Metabolism:Global:RNA processing:Membrane Transport:Environmental Information Processing:Transcription factors:Folding Sorting and Degradation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:DNA replication, recombination, and repair:DNA metabolism" 183 "Energy production and conversion:Ammonia permease:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:DNA mismatch repair enzyme (predicted ATPase):tRNA delta(2)-isopentenylpyrophosphate transferase:Na+/proline symporter:Spermidine/putrescine-binding periplasmic protein:Predicted thioesterase:Lauroyl/myristoyl acyltransferase:Truncated, possibly inactive, lysyl-tRNA synthetase (class II):Cytochrome c553:Uncharacterized conserved protein:Bacteriophage capsid protein:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Lipopolysaccharide biosynthesis:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Mismatch repair:General function prediction only:Function unknown:TIGR00051:miaA:genX:mutl:amt:L_thr_O3P_dcar:portal_lambda:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Cations and iron carrying compounds:Transport and binding proteins:tRNA and rRNA base modification:Protein synthesis:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Mobile and extrachromosomal element functions:Glycan Biosynthesis and Metabolism:Prophage functions:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin" 184 "Energy production and conversion:Cysteine synthase:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful):Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase):5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase:Dihydropteroate synthase and related enzymes:Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains:Predicted phosphatases:Phosphatidylglycerophosphate synthase:Predicted Zn-dependent peptidases:Predicted permease:Peroxiredoxin:Exonuclease III:ABC-type transport system involved in resistance to organic solvents, permease component:N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains):CMP-2-keto-3-deoxyoctulosonic acid synthetase:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Flagellar motor protein:3-deoxy-D-manno-octulosonic-acid transferase:Chorismate mutase:Transcriptional accessory protein:Mg/Co/Ni transporter MgtE (contains CBS domain):Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis:Uncharacterized protein involved in benzoate metabolism:Uncharacterized protein conserved in bacteria:Predicted membrane protein:Predicted N-formylglutamate amidohydrolase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Purine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Phenylalanine metabolism:Selenocompound metabolism:D-Arginine and D-ornithine metabolism:D-Alanine metabolism:Glutathione metabolism:Amino sugar and nucleotide sugar metabolism:Lipopolysaccharide biosynthesis:Glycerophospholipid metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Carbon fixation pathways in prokaryotes:Folate biosynthesis:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Bacterial chemotaxis:Flagellar assembly:Base excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00056:purH:mgtE:pgsA:xth:benE:glmS:glmU:lipoamide_DH:glut_syn:DHPS:GAPDH-I:Metabolism:Global:Cell Motility:Cellular Processes:Replication and Repair:Genetic Information Processing:Metabolism:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:DNA metabolism:Carbohydrate Metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cations and iron carrying compounds:Hypothetical proteins:Conserved:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Glutathione and analogs:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis:Fatty acid and phospholipid metabolism:Glycolysis/gluconeogenesis:Energy metabolism:Amino sugars:Central intermediary metabolism" 185 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Rhodanese-related sulfurtransferase:Predicted transcriptional regulators:Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis:Cation/multidrug efflux pump:Membrane-fusion protein:Flavodoxin reductases (ferredoxin-NADPH reductases) family 1:Transcriptional regulators:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):Cation transport ATPase:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Copper chaperone:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted mannose-6-phosphate isomerase:Uncharacterized copper-binding protein:Predicted cobalamin binding protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:TIGR00003:ispG_gcpE:leuA_bact:RND_mfp:CueR:Defense mechanisms:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Translation:Global:Metabolism:Regulatory functions:DNA interactions:Transport and binding proteins:Unknown substrate:Cations and iron carrying compounds:Amino acid biosynthesis:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 186 "Energy production and conversion:Polyprenyltransferase (cytochrome oxidase assembly factor):Phosphoglycerate dehydrogenase and related dehydrogenases:Putative translation initiation inhibitor, yjgF family:Predicted Zn-dependent proteases and their inactivated homologs:ABC-type branched-chain amino acid transport systems, ATPase component:ABC-type branched-chain amino acid transport systems, ATPase component:Aspartate/tyrosine/aromatic aminotransferase:Branched-chain amino acid ABC-type transport system, permease components:Transcriptional regulator:ABC-type branched-chain amino acid transport systems, periplasmic component:Demethylmenaquinone methyltransferase:Predicted transcriptional regulators:Long-chain acyl-CoA synthetases (AMP-forming):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Coenzyme F390 synthetase:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Uncharacterized conserved protein:Heme/copper-type cytochrome/quinol oxidase, subunit 3:Cation transport ATPase:Cytochrome oxidase assembly factor:ABC-type branched-chain amino acid transport system, permease component:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Oxidative phosphorylation:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Carbon fixation in photosynthetic organisms:Porphyrin and chlorophyll metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:cyoE_ctaB:ATPase_P-type:CoxB:Lipid Metabolism:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:Information storage and processing:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:Electron transport:Energy metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Metabolism:Amino Acid Metabolism" 187 "Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain:rRNA methylases:Molecular chaperone GrpE (heat shock protein):Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Permeases of the drug/metabolite transporter (DMT) superfamily:Uncharacterized protein conserved in bacteria:Molybdopterin-guanine dinucleotide biosynthesis protein A:Transcriptional regulators:Molybdopterin-guanine dinucleotide biosynthesis protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Sulfur relay system:General function prediction only:Function unknown:DNA_YbaB_EbfC:mobB:rRNA_methyl_3:trmU:hemN_rel:molyb_mobA:Heme, porphyrin, and cobalamin:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:tRNA and rRNA base modification:Protein synthesis:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Information storage and processing:Metabolism of Cofactors and Vitamins:Cellular processes and signaling:Metabolism:Poorly characterized:Molybdopterin" 188 "Energy production and conversion:Chaperonin GroEL (HSP60 family):ABC-type Fe3+-siderophore transport system, permease component:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Predicted membrane protein:Predicted ester cyclase:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:ABC transporters:RNA degradation:General function prediction only:Function unknown:efflux_EmrB:GroEL:LLM_2I7G:Cellular processes and signaling:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Protein fate:Protein folding and stabilization:Transport and binding proteins:Other:Genetic Information Processing:Metabolism:Poorly characterized" 189 "Sugar kinases, ribokinase family:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Site-specific recombinases, DNA invertase Pin homologs:Predicted naringenin-chalcone synthase:Phage terminase-like protein, large subunit:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Uncharacterized conserved protein:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Pentose phosphate pathway:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:phage_TIGR02216:phg_TIGR02218:Poorly characterized:Carbohydrate Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Mobile and extrachromosomal element functions:Prophage functions:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 190 "Energy production and conversion:Dihydroorotase and related cyclic amidohydrolases:Fumarase:Histidinol dehydrogenase:Queuine/archaeosine tRNA-ribosyltransferase:Predicted amidohydrolase:Protein-tyrosine-phosphatase:Deoxyribodipyrimidine photolyase:Apolipoprotein N-acyltransferase:ABC-type antimicrobial peptide transport system, ATPase component:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Long-chain fatty acid transport protein:Methylase of polypeptide chain release factors:Intracellular septation protein A:Membrane-bound lytic murein transglycosylase B:Ureidoglycolate hydrolase:Ketosteroid isomerase-related protein:ABC-type transport system, involved in lipoprotein release, permease component:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Histidine metabolism:beta-Alanine metabolism:Pyruvate metabolism:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:hisD:Q_tRNA_tgt:hemK_fam:lnt:fumC_II:lipoamide_DH:D-hydantoinase:TIGR02096:lolCE:MltB_2:Defense mechanisms:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:TCA cycle:Protein synthesis:tRNA and rRNA base modification:Protein fate:Protein and peptide secretion and trafficking:Protein modification and repair:Amino acid biosynthesis:Histidine family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 191 "Pyruvate kinase:Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake:ATP-dependent DNA ligase:Glucose/sorbosone dehydrogenases:Phage protein D:Predicted phage phi-C31 gp36 major capsid-like protein:Phage-related protein:Uncharacterized conserved protein:Predicted secreted protein:Carbohydrate transport and metabolism:Replication, recombination and repair:Glycolysis / Gluconeogenesis:Fructose and mannose metabolism:Purine metabolism:Bisphenol degradation:Glycerophospholipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Carbon fixation in photosynthetic organisms:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Base excision repair:Nucleotide excision repair:Mismatch repair:Non-homologous end-joining:General function prediction only:Function unknown:dprA:portal_HK97:put_DNA_pack:phgtail_TP901_1:NHEJ_ligase_prk:Intracellular trafficking, secretion, and vesicular transport:Cellular processes:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Metabolism:DNA transformation:Mobile and extrachromosomal element functions:Prophage functions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 192 "Energy production and conversion:Predicted GTPase, probable translation factor:Ornithine carbamoyltransferase:Adenylosuccinate synthase:Xanthosine triphosphate pyrophosphatase:Aspartate-semialdehyde dehydrogenase:Seryl-tRNA synthetase:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Predicted Zn-dependent proteases and their inactivated homologs:Nucleoside-diphosphate-sugar epimerases:Threonine synthase:Na+-driven multidrug efflux pump:Acetylglutamate kinase:Prolipoprotein diacylglyceryltransferase:RNase PH:Phosphoglyceromutase:UDP-N-acetylglucosamine enolpyruvyl transferase:Predicted sugar phosphate isomerase involved in capsule formation:Predicted hydrolase (HAD superfamily):Predicted SAM-dependent methyltransferases:Peroxiredoxin:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Uncharacterized bacitracin resistance protein:Tetrahydrodipicolinate N-succinyltransferase:3-methyladenine DNA glycosylase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Oxidative phosphorylation:Purine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Lysine biosynthesis:Arginine and proline metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Pyruvate metabolism:Methane metabolism:Thiamine metabolism:Vitamin B6 metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Base excision repair:General function prediction only:TIGR00042:TIGR00092:purA:thrC:kpsF:serS:lgt:tag:orni_carb_tr:undec_PP_bacA:argB:matE:dapD:gyrB:murA:asd_B:pgm_bpd_ind:lipoamide_DH:RNasePH:Defense mechanisms:Aspartate family:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Replication and Repair:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Sugars:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:RNA processing:Protein synthesis:tRNA aminoacylation:Protein fate:Protein modification and repair:Transport and binding proteins:Other:Unknown function:General:Amino acid biosynthesis:Metabolism:Glutamate family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 193 "Energy production and conversion:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:NADPH:quinone reductase and related Zn-dependent oxidoreductases:ABC-type dipeptide transport system, periplasmic component:Cell wall-associated hydrolases (invasion-associated proteins):Uracil-DNA glycosylase:Phage head maturation protease:Phage terminase-like protein, large subunit:Predicted phage phi-C31 gp36 major capsid-like protein:Phage-related protein:Uncharacterized conserved protein:Predicted secreted protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:ABC transporters:General function prediction only:Function unknown:portal_HK97:proheadase_HK97:major_cap_HK97:oligo_HPY:phgtail_TP901_1:phage_chp_gp8:phg_TIGR02218:phage_NlpC_fam:UDG_fam_dom:Metabolism:Cellular processes and signaling:Information storage and processing:Prophage functions:Mobile and extrachromosomal element functions:Amino acids, peptides and amines:Transport and binding proteins:Other:Protein fate:Environmental Information Processing:Poorly characterized:Membrane Transport" 194 "Energy production and conversion:Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit:Periplasmic serine proteases (ClpP class):Demethylmenaquinone methyltransferase:Spermidine/putrescine-binding periplasmic protein:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:Succinate dehydrogenase/fumarate reductase, cytochrome b subunit:Succinate dehydrogenase, hydrophobic anchor subunit:Amino acid transport and metabolism:Coenzyme transport and metabolism:Posttranslational modification, protein turnover, chaperones:Citrate cycle (TCA cycle):Oxidative phosphorylation:Toluene degradation:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:dhsB:sdhA_frdA_Gneg:succ_dehyd_cytB:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:TCA cycle:Energy metabolism:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Energy Metabolism:Carbohydrate Metabolism" 195 "Energy production and conversion:Alanyl-tRNA synthetase:Acetyl-CoA acetyltransferase:N-formylmethionyl-tRNA deformylase:Diaminopimelate epimerase:Superfamily II DNA and RNA helicases:Predicted permease:Signal transduction histidine kinase:ABC-type branched-chain amino acid transport systems, periplasmic component:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:ABC-type dipeptide transport system, periplasmic component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit:Cytochrome c biogenesis factor:Flagellar motor protein:Restriction endonuclease:Transcriptional regulators:Uncharacterized protein required for cytochrome oxidase assembly:Membrane protein involved in the export of O-antigen and teichoic acid:Protein related to penicillin acylase:Predicted ATPase:Arabinose efflux permease:O-acetylhomoserine sulfhydrylase:Lipid A core - O-antigen ligase and related enzymes:Signal transduction histidine kinase:Ornithine/acetylornithine aminotransferase:Signal transduction histidine kinase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Fatty acid biosynthesis:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Lysine biosynthesis:Lysine degradation:Penicillin and cephalosporin biosynthesis:Arginine and proline metabolism:Benzoate degradation:Tryptophan metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Aminoacyl-tRNA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial chemotaxis:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:pept_deformyl:sensory_box:alaS:nrfE:DapF:argD:OAH_OAS_sulfhy:AcAcCoA_reduct:3oxo_ACP_reduc:AcCoA-C-Actrans:TRAP_fused:tRNA_sel_U_synt:PDH_E1_alph_y:Defense mechanisms:Aspartate family:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:Electron transport:Pyruvate dehydrogenase:Fatty acid and phospholipid metabolism:Other:Biosynthesis:Regulatory functions:Small molecule interactions:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Protein fate:Protein modification and repair:Transport and binding proteins:Unknown substrate:Amino acid biosynthesis:Metabolism:Serine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 196 "Energy production and conversion:Molecular chaperone (small heat shock protein):Polyferredoxin:Ribosomal protein S6:Glycosyltransferase:ABC-type Fe3+-siderophore transport system, permease component:Periplasmic serine proteases (ClpP class):Esterase/lipase:Demethylmenaquinone methyltransferase:Arsenite efflux pump ACR3 and related permeases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type multidrug transport system, ATPase and permease components:Flagellar motor switch protein:Na+/H+ antiporter:ABC-type transport system involved in cytochrome c biogenesis, permease component:ABC-type protease/lipase transport system, ATPase and permease components:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Methane metabolism:ABC transporters:Bacterial chemotaxis:Flagellar assembly:Ribosome:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:S6:acr3:antiport_nhaC:ccmB:type_I_sec_PrtD:ccoG_rdxA_fixG:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Metabolism:Energy Metabolism:Genetic Information Processing:Translation:Environmental Information Processing:Membrane Transport:Cellular Processes:Cell Motility:Protein synthesis:Ribosomal proteins: synthesis and modification:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Anions:Cations and iron carrying compounds:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 197 "Mg2+ and Co2+ transporters:Predicted transcriptional regulators:Predicted endonuclease distantly related to archaeal Holliday junction resolvase:Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family:Predicted hydrolases of HD superfamily:Uncharacterized conserved protein:Signal transduction histidine kinase, nitrogen specific:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Histidine metabolism:Chlorocyclohexane and chlorobenzene degradation:Bisphenol degradation:Toluene degradation:Polycyclic aromatic hydrocarbon degradation:Naphthalene degradation:Aminobenzoate degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism" 198 "Chemotaxis protein histidine kinase and related kinases:FOG: CheY-like receiver:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:Flagellar biosynthesis/type III secretory pathway ATPase:Flagellar biosynthesis/type III secretory pathway protein:Flagellar capping protein:Methylase of chemotaxis methyl-accepting proteins:Flagellar motor switch protein:Flagellar hook-basal body protein:Flagellar biosynthesis/type III secretory pathway lipoprotein:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Two-component system:Bacterial chemotaxis:Flagellar assembly:Signal transduction mechanisms:fliE:fliF:fliG:fliI_yscN:Intracellular trafficking, secretion, and vesicular transport:Cellular processes:ATP-proton motive force interconversion:Energy metabolism:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Cellular processes and signaling:Information storage and processing:Chemotaxis and motility" 199 "Energy production and conversion:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Hydrogenase maturation factor:Hydrogenase maturation factor:Zn finger protein HypA/HybF (possibly regulating hydrogenase expression):Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase:Hydrogenase maturation factor:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Ni,Fe-hydrogenase maturation factor:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Rubredoxin:Transcriptional regulators:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:hydrog_prot:hypB:hypC_hupF:hypD:hypA:hypE:hydrog_HybE:Membrane Transport:Environmental Information Processing:Metabolism:Cellular processes and signaling:Information storage and processing:Protein modification and repair:Protein fate:Poorly characterized" 200 "Cysteine synthase:Predicted metal-dependent hydrolase:ATP-dependent Lon protease, bacterial type:Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Enoyl-[acyl-carrier-protein] reductase (NADH):cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:MoxR-like ATPases:UDP-glucose pyrophosphorylase:Glycosyltransferases, probably involved in cell wall biogenesis:Predicted glycosyltransferases:Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains:Uncharacterized protein conserved in bacteria:D-alanyl-D-alanine carboxypeptidase:Phosphate starvation-inducible protein PhoH, predicted ATPase:Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain):Beta-glucanase/Beta-glucan synthetase:Putative arginyl-tRNA:protein arginylyltransferase:Membrane-bound lytic murein transglycosylase B:Uncharacterized iron-regulated protein:Uncharacterized protein involved in exopolysaccharide biosynthesis:Poly(3-hydroxyalkanoate) synthetase:Putative virion core protein (lumpy skin disease virus):Poly-beta-hydroxyalkanoate depolymerase:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pentose and glucuronate interconversions:Galactose metabolism:Fatty acid biosynthesis:Cysteine and methionine metabolism:Selenocompound metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Butanoate metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00043:TIGR00244:lon:galU:PHA_synth_I:PHB_depoly_PhaZ:two_anch:MltB_2:rpoH_proteo:DNA interactions:Regulatory functions:Degradation:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Transcription:Genetic Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Protein fate:Carbohydrate Metabolism:Degradation of proteins, peptides, and glycopeptides:Hypothetical proteins:Domain:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Other:Protein synthesis:Transcription factors:Transcription" 201 "Energy production and conversion:3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases:NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases:NADH:ubiquinone oxidoreductase 49 kD subunit 7:NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K):Collagenase and related proteases:NADH:ubiquinone oxidoreductase subunit 3 (chain A):NADH:ubiquinone oxidoreductase subunit 6 (chain J):NADH:ubiquinone oxidoreductase subunit 1 (chain H):NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G):Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I):NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit:NADH:ubiquinone oxidoreductase 24 kD subunit:Putative lipid carrier protein:Coenzyme transport and metabolism:Lipid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Ubiquinone and other terpenoid-quinone biosynthesis:Oxidative phosphorylation:Metabolic pathways:Biosynthesis of secondary metabolites:TIGR00148:nuoB_fam:NuoD:NuoI:NuoG:Metabolism:Energy Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Energy metabolism:Electron transport:Unknown function:General:Cellular processes and signaling:Metabolism" 202 "Phosphoribosyl-AMP cyclohydrolase:Integral membrane protein, interacts with FtsH:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Preprotein translocase subunit SecB:Lysophospholipase L1 and related esterases:Membrane-bound lytic murein transglycosylase:Protein affecting phage T7 exclusion by the F plasmid:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted transmembrane transcriptional regulator (anti-sigma factor):Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Histidine metabolism:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:RNA polymerase:Protein export:Bacterial secretion system:General function prediction only:Function unknown:secB:sigma70-ECF:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Metabolism:Global:Protein and peptide secretion and trafficking:Protein fate:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Metabolism of Terpenoids and Polyketides:Amino Acid Metabolism:Information storage and processing:Lipid Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 203 "Energy production and conversion:Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain:Riboflavin synthase beta-chain:Glucan phosphorylase:Isoleucyl-tRNA synthetase:3-isopropylmalate dehydratase large subunit:3-isopropylmalate dehydratase small subunit:Mg-dependent DNase:3,4-dihydroxy-2-butanone 4-phosphate synthase:5-enolpyruvylshikimate-3-phosphate synthase:Anthranilate/para-aminobenzoate synthases component I:Preprotein translocase subunit SecY:Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A):Acetyl-CoA hydrolase:Phosphoribosylpyrophosphate synthetase:Pyruvate kinase:Phosphatidylserine decarboxylase:F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein):Phosphatidylserine synthase:NAD/NADP transhydrogenase beta subunit:Choline-glycine betaine transporter:L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases:Preprotein translocase subunit SecG:Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins:Predicted periplasmic solute-binding protein:NAD/NADP transhydrogenase alpha subunit:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Oxidative phosphorylation:Purine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Phenylalanine tyrosine and tryptophan biosynthesis:Starch and sucrose metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:C5-Branched dibasic acid metabolism:Carbon fixation in photosynthetic organisms:Riboflavin metabolism:Nicotinate and nicotinamide metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:General function prediction only:TIGR00010:efp:lumazine-synth:PS_decarb_rel:leuC:leuD:TIGR00247:glpX:valS:pssA:ribB:pntA:trpE_most:secG:bcct:3a0501s007:pyruv_kin:ATP_synt_delta:ribP_PPkin:aroA:FGAM_synth_II:P_ylase:YgfH_subfam:Intracellular trafficking, secretion, and vesicular transport:Unknown function:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:Electron transport:Glycolysis/gluconeogenesis:Pentose phosphate pathway:Biosynthesis and degradation of polysaccharides:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Protein synthesis:tRNA aminoacylation:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Other:Hypothetical proteins:Conserved:Metabolism:Enzymes of unknown specificity:General:Amino acid biosynthesis:Aromatic amino acid family:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Riboflavin, FMN, and FAD:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 204 "Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Universal stress protein UspA and related nucleotide-binding proteins:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Spermidine/putrescine-binding periplasmic protein:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:ABC-type dipeptide transport system, periplasmic component:ABC-type amino acid transport system, permease component:ABC-type polar amino acid transport system, ATPase component:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:ABC-type Fe3+ transport system, periplasmic component:Uncharacterized conserved protein:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type uncharacterized transport systems, ATPase components:ABC-type uncharacterized transport system, permease component:ABC-type proline/glycine betaine transport system, ATPase component:ABC-type proline/glycine betaine transport system, permease component:Poly-beta-hydroxyalkanoate depolymerase:ABC-type amino acid transport system, permease component:ABC-type uncharacterized transport system, permease component:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:potA:HEQRo_perm_3TM:PHB_depoly_PhaZ:ABC_choXWV_ATP:ABC_choXWV_perm:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Amino acids, peptides and amines:Transport and binding proteins:Degradation:Fatty acid and phospholipid metabolism" 205 "" 206 "DNA-directed RNA polymerase specialized sigma subunit:Flagellar motor component:Flagellar biosynthesis pathway, component FlhA:Flagellar biosynthesis pathway, component FliP:Flagellar basal body rod protein:Flagellar basal body-associated protein:Flagellar basal-body P-ring protein:Flagellar hook capping protein:Flagellar motor switch protein:Flagellar basal body L-ring protein:Flagellar basal body rod protein:Type III secretory pathway, component EscS:Transcription:Cell motility:Two-component system:Bacterial chemotaxis:Flagellar assembly:RNA polymerase:fliP:FlgC:fliM_switch:FlhA:fliQ:FliA_WhiG:fliN:flgG_G_neg:Intracellular trafficking, secretion, and vesicular transport:Cellular processes:Transcription:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Genetic Information Processing:Chemotaxis and motility:Information storage and processing:Cellular processes and signaling" 207 "Energy production and conversion:Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:Cytidine deaminase:Riboflavin synthase alpha chain:Molybdenum cofactor biosynthesis enzyme:Membrane protease subunits, stomatin/prohibitin homologs:Ketopantoate hydroxymethyltransferase:Panthothenate synthetase:Predicted flavoprotein:Anthranilate/para-aminobenzoate synthases component II:Anthranilate phosphoribosyltransferase:Glutathione S-transferase:Glycine/D-amino acid oxidases (deaminating):Bacterial cell division membrane protein:Nitroreductase:Predicted hydrolase (HAD superfamily):Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities:Glutamine synthetase adenylyltransferase:Aspartate/tyrosine/aromatic aminotransferase:Nicotinic acid phosphoribosyltransferase:Uncharacterized protein containing LysM domain:dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Uncharacterized protein involved in cysteine biosynthesis:Uncharacterized protein involved in benzoate metabolism:Uncharacterized protein conserved in bacteria:Predicted secreted protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pyrimidine metabolism:Cysteine and methionine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:beta-Alanine metabolism:Selenocompound metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Glyoxylate and dicarboxylate metabolism:Riboflavin metabolism:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:panC:ribE:panB:trpG_papA:moaC:benE:rmlC:trpD:cyt_deam_tetra:HAD-SF-IA-v3:NAPRTase:ftsW:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Cellular processes:Cell division:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Aromatic amino acid family:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Pantothenate and coenzyme A:Riboflavin, FMN, and FAD:Pyridine nucleotides:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins" 208 "Energy production and conversion:Xaa-Pro aminopeptidase:Succinyl-CoA synthetase, beta subunit:F0F1-type ATP synthase, alpha subunit:Succinyl-CoA synthetase, alpha subunit:Molybdopterin converting factor, large subunit:Nuclease subunit of the excinuclease complex:ABC-type branched-chain amino acid transport systems, ATPase component:ABC-type branched-chain amino acid transport systems, ATPase component:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Biotin carboxyl carrier protein:Branched-chain amino acid ABC-type transport system, permease components:2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes:RNase P protein component:Uncharacterized conserved protein:Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog):Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:TRAP-type C4-dicarboxylate transport system, large permease component:TRAP-type C4-dicarboxylate transport system, periplasmic component:Uncharacterized MobA-related protein:Citrate lyase beta subunit:Leu/Phe-tRNA-protein transferase:Predicted Zn peptidase:Predicted membrane protein:Acetyl/propionyl-CoA carboxylase, alpha subunit:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Fatty acid biosynthesis:Oxidative phosphorylation:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Tryptophan metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:C5-Branched dibasic acid metabolism:Carbon fixation pathways in prokaryotes:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Nucleotide excision repair:Sulfur relay system:General function prediction only:Function unknown:rnpA:uvrC:2oxo_dh_E1:TIGR00278:accC:BCCP:aat:dctM:dctP:atpA:sucCoAbeta:sucCoAalpha:sucB:lipoamide_DH:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:TCA cycle:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:RNA processing:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Hypothetical proteins:Conserved:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 209 "Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Pseudouridine synthase:Mismatch repair ATPase (MutS family):Protoheme ferro-lyase (ferrochelatase):Cytidylate kinase:Folate-dependent phosphoribosylglycinamide formyltransferase PurN:Preprotein translocase subunit SecF:Carbamoylphosphate synthase large subunit (split gene in MJ):ATPase involved in DNA repair:Superfamily II DNA and RNA helicases:ABC-type multidrug transport system, permease component:Predicted hydrolase (HAD superfamily):Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type multidrug transport system, ATPase component:ABC-type multidrug transport system, ATPase and permease components:Predicted glycosyltransferases:Predicted membrane GTPase involved in stress response:Uncharacterized conserved protein:SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase:16S RNA G1207 methylase RsmC:Uncharacterized Fe-S protein:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:One carbon pool by folate:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:RNA degradation:Protein export:Bacterial secretion system:Mismatch repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:hemH:small_GTP:TruB:recN:PurN:2A0604s01:mutS1:CPSaseII_lrg:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Biosynthesis of cofactors, prosthetic groups, and carriers:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Pyrimidine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Protein fate:Protein and peptide secretion and trafficking:Unknown function:General:Metabolism:Heme, porphyrin, and cobalamin:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 210 "Glutathione peroxidase:Gamma-glutamyltransferase:Predicted glutathione S-transferase:Signal recognition particle GTPase:ABC-type antimicrobial peptide transport system, ATPase component:Uncharacterized conserved protein:Putative NADP-dependent oxidoreductases:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Uncharacterized conserved protein:Gluconolactonase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Tyrosine metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:Glutathione metabolism:Arachidonic acid metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:General function prediction only:Function unknown:g_glut_trans:ffh:TIGR03438:unchr_TIGR03440:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Cellular processes and signaling:Glutathione and analogs:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Enzymes of unknown specificity:Global:Unknown function:Membrane Transport:Environmental Information Processing:Protein and peptide secretion and trafficking:Folding Sorting and Degradation:Genetic Information Processing:Protein fate:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized" 211 "Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:ATPases involved in chromosome partitioning:Flagellar basal body P-ring biosynthesis protein:Flagellar biosynthesis pathway, component FliP:Methylase of chemotaxis methyl-accepting proteins:Flagellar biosynthesis pathway, component FlhB:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Flagellin-specific chaperone FliS:Flagellar biosynthesis pathway, component FliR:Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Two-component system:Bacterial chemotaxis:Flagellar assembly:RNA polymerase:Function unknown:Signal transduction mechanisms:flhB:fliP:fliR:rpoN_sigma:flgA_cterm:Intracellular trafficking, secretion, and vesicular transport:Transcription factors:Transcription:Genetic Information Processing:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Poorly characterized:Transcription:Cellular processes and signaling:Information storage and processing:Chemotaxis and motility:Cellular processes" 212 "Signal transduction histidine kinase:DNA polymerase I - 3'-5' exonuclease and polymerase domains:Predicted nucleic-acid-binding protein implicated in transcription termination:ATP phosphoribosyltransferase involved in histidine biosynthesis:Predicted integral membrane protein:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Purine metabolism:Pyrimidine metabolism:Histidine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:DNA replication:Base excision repair:Nucleotide excision repair:Homologous recombination:Function unknown:Signal transduction mechanisms:pola:Cellular processes and signaling:Metabolism:Poorly characterized:Information storage and processing:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Metabolism:Global:Replication and Repair:Genetic Information Processing:Amino Acid Metabolism:Nucleotide Metabolism" 213 "Energy production and conversion:Ribonuclease HI:Ni,Fe-hydrogenase I large subunit:Fructose-2,6-bisphosphatase:Esterase/lipase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcriptional regulator:Predicted CoA-binding protein:Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase:Signal transduction protein containing GAF and PtsI domains:Signal transduction histidine kinase, nitrogen specific:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Porphyrin and chlorophyll metabolism:Metabolic pathways:Two-component system:Phosphotransferase system (PTS):DNA replication:General function prediction only:Signal transduction mechanisms:PTS_I_fam:Poorly characterized:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 214 "tRNA-dihydrouridine synthase:Cysteinyl-tRNA synthetase:Predicted S-adenosylmethionine-dependent methyltransferase:Mannitol-1-phosphate/altronate dehydrogenases:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:ATPase components of ABC transporters with duplicated ATPase domains:Signal transduction histidine kinase:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Sortase and related acyltransferases:Transcriptional regulators:Predicted acyltransferase:Transcriptional regulators:Altronate dehydratase:DNA-binding HTH domain-containing proteins:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase, nitrogen specific:Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta):ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pentose and glucuronate interconversions:Valine leucine and isoleucine degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Carbon fixation pathways in prokaryotes:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Protein export:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:cysS:Carbohydrate Metabolism:Protein synthesis:tRNA aminoacylation:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Translation:Genetic Information Processing:Amino Acid Metabolism:Energy Metabolism" 215 "Exopolyphosphatase:Uncharacterized conserved protein:ABC-type branched-chain amino acid transport systems, ATPase component:Nucleoside-diphosphate-sugar epimerases:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Nicotinic acid mononucleotide adenylyltransferase:Sortase and related acyltransferases:Transcriptional regulator:Predicted phosphohydrolases:2'-5' RNA ligase:Dihydroneopterin aldolase:Thiamine pyrophosphokinase:Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase:Acetyltransferases, including N-acetylases of ribosomal proteins:Transcriptional regulators:Sugar transferases involved in lipopolysaccharide synthesis:Uncharacterized protein conserved in bacteria:Uncharacterized protein involved in biosynthesis of c-type cytochromes:Uncharacterized protein conserved in bacteria:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Phosphonate and phosphinate metabolism:Thiamine metabolism:Nicotinate and nicotinamide metabolism:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:cyt_tran_rel:sensory_box:folB_dom:thi_PPkinase:2_5_ligase:RNA processing:Transcription:Small molecule interactions:Regulatory functions:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers" 216 "Energy production and conversion:Excinuclease ATPase subunit:Acetyl-CoA acetyltransferase:Peptide methionine sulfoxide reductase:Uncharacterized conserved protein:Ca2+/Na+ antiporter:ATPases with chaperone activity, ATP-binding subunit:Transcriptional regulator:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Periplasmic serine proteases (ClpP class):Glutathione S-transferase:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):ABC-type multidrug transport system, ATPase and permease components:3-hydroxyacyl-CoA dehydrogenase:Uncharacterized protein conserved in bacteria:Transcriptional regulator of heat shock gene:Uncharacterized protein required for formate dehydrogenase activity:Transcriptional regulators:NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit:NADH:ubiquinone oxidoreductase 24 kD subunit:ATPase related to the helicase subunit of the Holliday junction resolvase:Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component:Uncharacterized anaerobic dehydrogenase:Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component:Uncharacterized conserved protein:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Ascorbate and aldarate metabolism:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Glutathione metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Terpenoid backbone biosynthesis:Limonene and pinene degradation:Caprolactam degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Nucleotide excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:fdhD_narQ:hrcA:TIGR00367:msrA:uvra:Fdh-alpha:AcCoA-C-Actrans:quinone_pig3:chaperone_ClpB:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Carbohydrate Metabolism:Energy metabolism:Electron transport:Fatty acid and phospholipid metabolism:Other:Regulatory functions:DNA interactions:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein folding and stabilization:Cellular processes:Adaptations to atypical conditions:Unknown function:Enzymes of unknown specificity:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Global:Signal Transduction:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism" 217 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Glycosyltransferase:Nucleoside-diphosphate-sugar epimerases:Predicted dehydrogenases and related proteins:Threonine dehydrogenase and related Zn-dependent dehydrogenases:UDP-glucose 4-epimerase:dTDP-D-glucose 4,6-dehydratase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Galactose metabolism:Valine leucine and isoleucine degradation:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:Ku_bact:Cellular processes and signaling:Carbohydrate Metabolism:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Biosynthesis of Other Secondary Metabolites:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Metabolism:Metabolism:Poorly characterized" 218 "Glutamine phosphoribosylpyrophosphate amidotransferase:Predicted Zn-dependent proteases and their inactivated homologs:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase):DNA modification methylase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Recombinational DNA repair ATPase (RecF pathway):Metal-dependent hydrolases of the beta-lactamase superfamily I:Thiamine pyrophosphokinase:ABC-type metal ion transport system, permease component:Ribosomal protein L11 methylase:Cytochrome c-type biogenesis protein CcmE:Rhodanese-related sulfurtransferase:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Thiamine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Homologous recombination:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:queA:purF:thi_PPkinase:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Purine ribonucleotide biosynthesis:Carbohydrate Metabolism:Protein synthesis:tRNA and rRNA base modification:Biosynthesis of cofactors, prosthetic groups, and carriers:Thiamine:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism" 219 "FOG: CheY-like receiver:TRAP-type mannitol/chloroaromatic compound transport system, large permease component:Secondary metabolites biosynthesis, transport and catabolism:Signal transduction mechanisms:pufM:puhA:pufL:Cellular processes and signaling:Metabolism:Photosynthesis:Energy metabolism" 220 "Energy production and conversion:Glycosyltransferase:Chaperonin GroEL (HSP60 family):Isocitrate/isopropylmalate dehydrogenase:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):MoxR-like ATPases:Flagellar biosynthesis pathway, component FlhA:Micrococcal nuclease (thermonuclease) homologs:Transcriptional regulators:Site-specific recombinases, DNA invertase Pin homologs:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Protein containing von Willebrand factor type A (vWA) domain:DNA G:T-mismatch repair endonuclease:Uncharacterized protein conserved in bacteria:Predicted DNA-binding protein with the Helix-hairpin-helix motif:Site-specific recombinase XerD:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Benzoate degradation:Glyoxylate and dicarboxylate metabolism:Butanoate metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:Flagellar assembly:RNA degradation:General function prediction only:Function unknown:vsr:FlhA:TTC:TIGR02118:GroEL:protocat_pcaD:rSAM_link_UDG:Intracellular trafficking, secretion, and vesicular transport:DNA metabolism:Other:Energy metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Folding Sorting and Degradation:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Protein folding and stabilization:Carbohydrate Metabolism:Cellular processes:Chemotaxis and motility:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Protein fate:DNA replication, recombination, and repair" 221 "Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase):Predicted methyltransferases:Sugar kinases, ribokinase family:Predicted permeases:ABC-type branched-chain amino acid transport systems, periplasmic component:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:Uncharacterized membrane protein, putative virulence factor:UDP-N-acetylmuramate-alanine ligase:Predicted endonuclease distantly related to archaeal Holliday junction resolvase:UDP-N-acetylmuramate dehydrogenase:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Beta-glucosidase-related glycosidases:D-Tyr-tRNAtyr deacylase:Uncharacterized protein with SCP/PR1 domains:UTP:GlnB (protein PII) uridylyltransferase:Uncharacterized conserved protein:Predicted membrane protein:Lyzozyme M1 (1,4-beta-N-acetylmuramidase):ABC-type spermidine/putrescine transport systems, ATPase components:Predicted phage phi-C31 gp36 major capsid-like protein:Flp pilus assembly protein, secretin CpaC:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Fructose and mannose metabolism:D-Glutamine and D-glutamate metabolism:D-Alanine metabolism:Glutathione metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Metabolic pathways:Two-component system:General function prediction only:Function unknown:TIGR00096:murB:TIGR00256:murC:potA:D_ala_D_alaTIGR:glut_syn:major_cap_HK97:UTase_glnD:mviN:beta_rpt_yvtn:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis of cofactors, prosthetic groups, and carriers:Carbohydrate Metabolism:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Environmental Information Processing:Signal Transduction:Global:Metabolism:Regulatory functions:Protein interactions:Protein synthesis:tRNA aminoacylation:Transport and binding proteins:Amino acids, peptides and amines:Mobile and extrachromosomal element functions:Prophage functions:Unknown function:Enzymes of unknown specificity:General:Metabolism:Glutathione and analogs:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 222 "" 223 "Energy production and conversion:ABC-type cobalt transport system, permease component CbiQ and related transporters:Signal transduction histidine kinase:Phosphopantetheine adenylyltransferase:MoxR-like ATPases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Parvulin-like peptidyl-prolyl isomerase:Predicted permeases:Glutamate racemase:UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:UDP-glucose pyrophosphorylase:Uncharacterized conserved protein:Ribonucleases G and E:Outer membrane protein:Periplasmic protein involved in polysaccharide export:Predicted P-loop-containing kinase:DnaK suppressor protein:Phosphotransferase system, mannose/fructose-specific component IIA:Small protein A (tmRNA-binding):Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Galactose metabolism:D-Glutamine and D-glutamate metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Lipopolysaccharide biosynthesis:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Phosphotransferase system (PTS):RNA degradation:Bacterial secretion system:General function prediction only:Signal transduction mechanisms:cyt_tran_rel:RNaseEG:galU:type_I_sec_TolC:dksA:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Porins:Transport and binding proteins:Degradation of RNA:Transcription:Small molecule interactions:Regulatory functions:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Carbohydrate Metabolism" 224 "Dihydroorotase and related cyclic amidohydrolases:Ribosomal protein L23:Ribosomal protein S9:Enolase:Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit:Ribosomal protein L16/L10E:Ribosomal protein L15:Preprotein translocase subunit SecY:Ribosomal protein L32:Preprotein translocase subunit SecF:Preprotein translocase subunit SecD:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:IMP dehydrogenase/GMP reductase:Aspartate carbamoyltransferase, catalytic chain:Adenylate kinase and related kinases:Signal peptidase I:GTPase:Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase):Ribosomal protein L30/L7E:Preprotein translocase subunit YajC:Invasion protein B, involved in pathogenesis:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Glycolysis / Gluconeogenesis:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:RNA degradation:Protein export:Bacterial secretion system:General function prediction only:small_GTP:asp_carb_tr:yajC:pyrC_multi:2A0604s01:3a0501s007:rpmF_bact:eno:parC_Gneg:rplO_bact:rplP_bact:IMP_dehydrog:rpmD_bact:adk:sigpep_I_bact:polynuc_phos:Intracellular trafficking, secretion, and vesicular transport:Protein and peptide secretion and trafficking:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Purine ribonucleotide biosynthesis:Pyrimidine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:Degradation of RNA:Protein synthesis:Ribosomal proteins: synthesis and modification:Protein fate:Metabolism:Unknown function:General:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 225 "Aminoacyl-tRNA biosynthesis:Genetic Information Processing:Translation" 226 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Uncharacterized conserved protein:Predicted Fe-S oxidoreductases:NifU homolog involved in Fe-S cluster formation:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Nitrogenase subunit NifH (ATPase):Nitrogenase molybdenum-iron protein, alpha and beta chains:Predicted NADH:ubiquinone oxidoreductase, subunit RnfB:Uncharacterized protein conserved in bacteria:Predicted NADH:ubiquinone oxidoreductase, subunit RnfC:Predicted NADH:ubiquinone oxidoreductase, subunit RnfA:Predicted NADH:ubiquinone oxidoreductase, subunit RnfD:Predicted NADH:ubiquinone oxidoreductase, subunit RnfG:Predicted NADH:ubiquinone oxidoreductase, subunit RnfE:Amino acid transport and metabolism:Inorganic ion transport and metabolism:Lysine biosynthesis:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Thiamine metabolism:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Sulfur relay system:General function prediction only:Function unknown:TIGR00049:nifD:nifE:nifN:nifK:nifH:nifB:rnfA:rnfB:rnfC:rnfD:rnfG:rnfE:nifX:TIGR02935:FeS_nifS:Biosynthesis of cofactors, prosthetic groups, and carriers:Electron transport:Energy metabolism:Nitrogen fixation:Central intermediary metabolism:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Other" 227 "NhaP-type Na+/H+ and K+/H+ antiporters:Geranylgeranyl pyrophosphate synthase:Nucleoside-diphosphate-sugar epimerases:Glycine cleavage system H protein (lipoate-binding):Ribosomal protein S1:Predicted dehydrogenase:Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain:Uncharacterized conserved protein:Predicted homoserine dehydrogenase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Ribosome:General function prediction only:Function unknown:gcvP:gcvH:rpsA:Cellular processes and signaling:Amino Acid Metabolism:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:Amino acids and amines:Protein synthesis:Ribosomal proteins: synthesis and modification:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 228 "Energy production and conversion:NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases:Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit:NADH:ubiquinone oxidoreductase 49 kD subunit 7:NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K):NADH:ubiquinone oxidoreductase subunit 3 (chain A):NADH:ubiquinone oxidoreductase subunit 6 (chain J):Heme/copper-type cytochrome/quinol oxidases, subunit 1:NADH:ubiquinone oxidoreductase 27 kD subunit:NADH:ubiquinone oxidoreductase subunit 1 (chain H):NADH:ubiquinone oxidoreductase subunit 2 (chain N):NADH:ubiquinone oxidoreductase subunit 4 (chain M):NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G):NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit:NADH:ubiquinone oxidoreductase 24 kD subunit:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Inorganic ion transport and metabolism:Oxidative phosphorylation:Benzoate degradation:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Function unknown:NDH_I_N:nuoB_fam:nuoE_fam:nuoF_fam:NuoC_fam:NuoD:NDH_I_M:NuoG:NDH_I_L:CtaD_CoxA:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Electron transport" 229 "Energy production and conversion:NAD synthase:Glycosidases:ABC-type sugar transport system, permease component:Predicted transcriptional regulators:Cold shock proteins:Lauroyl/myristoyl acyltransferase:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Cu/Zn superoxide dismutase:Cation transport ATPase:Copper chaperone:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:Cytochrome b:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Galactose metabolism:Oxidative phosphorylation:Cyanoamino acid metabolism:Starch and sucrose metabolism:Lipopolysaccharide biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:TIGR00003:cinA_cterm:CueR:BGL:Information storage and processing:Cations and iron carrying compounds:Transport and binding proteins:DNA replication, recombination, and repair:DNA metabolism:DNA interactions:Regulatory functions:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism" 230 "TRAP-type mannitol/chloroaromatic compound transport system, large permease component:Secondary metabolites biosynthesis, transport and catabolism:pufM:pufL:Photosynthesis:Energy metabolism:Metabolism" 231 "Energy production and conversion:Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain:Glutamate synthase domain 2:Glutathione peroxidase:Predicted glutathione S-transferase:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Aldo/keto reductases, related to diketogulonate reductase:Small-conductance mechanosensitive channel:2-keto-3-deoxy-6-phosphogluconate aldolase:Uncharacterized conserved protein:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Uncharacterized conserved protein:Putative NADP-dependent oxidoreductases:Predicted acyltransferase:Predicted Zn-dependent hydrolases of the beta-lactamase fold:Uncharacterized protein, similar to the N-terminal domain of Lon protease:Arabinose efflux permease:Uncharacterized conserved protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fatty acid metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Tyrosine metabolism:Glutathione metabolism:Arachidonic acid metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Glyoxylate and dicarboxylate metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:PduO_Nterm:eda:FGAM_synth_I:TIGR03438:unchr_TIGR03440:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Enzymes of unknown specificity:Carbohydrate Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Cellular processes and signaling:Metabolism:Poorly characterized:Unknown function:Purine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Entner-Doudoroff:Energy metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism" 232 "Periplasmic protein TonB, links inner and outer membranes:Biopolymer transport proteins:Biopolymer transport protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:ABC-type Fe3+ transport system, periplasmic component:Bacterioferritin (cytochrome b1):Na+/melibiose symporter and related transporters:Predicted NAD/FAD-binding protein:Uncharacterized iron-regulated protein:Predicted periplasmic lipoprotein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Anti-sigma factor:ABC-type enterochelin transport system, periplasmic component:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:ABC transporters:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:bfr:tonB_Cterm:anti_sig_ChrR:exbB:ExbD_1:sigma70-ECF:Intracellular trafficking, secretion, and vesicular transport:Transport and binding proteins:Other:Regulatory functions:Membrane Transport:Environmental Information Processing:Transcription:Genetic Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds" 233 "Short-chain dehydrogenases of various substrate specificities:ABC-type sugar transport system, permease component:Predicted TIM-barrel enzyme:Predicted glutathione S-transferase:Glycosyltransferase:Putative transcription activator:ABC-type sugar transport systems, permease components:ABC-type Fe3+ transport system, permease component:Type II secretory pathway, pullulanase PulA and related glycosidases:ABC-type sugar transport system, periplasmic component:Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase:ABC-type sugar transport systems, ATPase components:ABC-type uncharacterized transport system, duplicated ATPase component:Predicted membrane protein:Predicted phage phi-C31 gp36 major capsid-like protein:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Cyanoamino acid metabolism:Starch and sucrose metabolism:Thiamine metabolism:Biosynthesis of secondary metabolites:ABC transporters:General function prediction only:Function unknown:thylakoid_BtpA:phge_HK97_gp10:glgX_debranch:BGL:Protein fate:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:Information storage and processing:Prophage functions:Mobile and extrachromosomal element functions:Protein folding and stabilization" 234 "Energy production and conversion:Diaminopimelate decarboxylase:Chorismate synthase:Thymidylate kinase:Replicative DNA helicase:3-dehydroquinate synthetase:Nucleotide-binding protein implicated in inhibition of septum formation:Signal transduction histidine kinase:Predicted sugar phosphatases of the HAD superfamily:Shikimate kinase:Predicted permeases:Transcription termination factor:ABC-type Fe3+ transport system, permease component:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Tetraacyldisaccharide-1-P 4'-kinase:Large-conductance mechanosensitive channel:Multiple antibiotic transporter:Transcriptional activator of acetoin/glycerol metabolism:Uncharacterized conserved protein:ABC-type thiamine transport system, periplasmic component:Uncharacterized protein conserved in bacteria:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pyrimidine metabolism:Lysine biosynthesis:Phenylalanine tyrosine and tryptophan biosynthesis:Glutathione metabolism:Lipopolysaccharide biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:DNA replication:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:aroC:DTMP_kinase:mscL:sensory_box:TIGR00427:DnaB:lpxK:lysA:sfuA:aroB:gluta_reduc_2:HAD-SF-IIA-hyp4:nusB:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Regulatory functions:Small molecule interactions:DNA metabolism:DNA replication, recombination, and repair:Transcription:Transcription factors:Transport and binding proteins:Other:Cellular processes:Adaptations to atypical conditions:Unknown function:General:Amino acid biosynthesis:Aromatic amino acid family:Aspartate family:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 235 "Energy production and conversion:ABC-type sugar transport system, permease component:Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Protease subunit of ATP-dependent Clp proteases:Cell wall-associated hydrolases (invasion-associated proteins):Methyl-accepting chemotaxis protein:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Flagellar biosynthesis/type III secretory pathway ATPase:Transcriptional regulators of sugar metabolism:DNA-binding HTH domain-containing proteins:Phage head maturation protease:Predicted membrane protein:Predicted phage phi-C31 gp36 major capsid-like protein:Phage-related protein:Outer membrane receptor for monomeric catechols:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:ABC transporters:Flagellar assembly:General function prediction only:Function unknown:Signal transduction mechanisms:fliI_yscN:portal_HK97:proheadase_HK97:major_cap_HK97:TonB-siderophor:phage_chp_gp8:phage_NlpC_fam:Intracellular trafficking, secretion, and vesicular transport:Membrane Transport:Mobile and extrachromosomal element functions:Prophage functions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Environmental Information Processing:Transport and binding proteins:Other:Protein fate:ATP-proton motive force interconversion:Energy metabolism:Cell Motility:Cellular Processes:Porins" 236 "Energy production and conversion:Zn-dependent hydrolases, including glyoxylases:Esterase/lipase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Glycosyltransferases, probably involved in cell wall biogenesis:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted membrane protein:Cytochrome P450:Response regulator containing a CheY-like receiver domain and a GGDEF domain:Response regulator with putative antiterminator output domain:Phage head maturation protease:ABC-type spermidine/putrescine transport systems, ATPase components:Phage-related protein:Site-specific recombinase XerD:Uncharacterized protein with a bacterial SH3 domain homologue:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Bisphenol degradation:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:RNA polymerase:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:portal_HK97:proheadase_HK97:sigma70-ECF:Metabolism:Global:Signal Transduction:Metabolism:Membrane Transport:Environmental Information Processing:Transcription:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Other:Nucleotide Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Signal transduction:Prophage functions:Mobile and extrachromosomal element functions:Other:Protein fate" 237 "Energy production and conversion:Superfamily I DNA and RNA helicases:Stress-induced morphogen (activity unknown):Glutaredoxin-related protein:ATP-dependent Zn proteases:ABC-type multidrug transport system, ATPase and permease components:NADH dehydrogenase, FAD-containing subunit:Cytochrome bd-type quinol oxidase, subunit 1:Cytochrome bd-type quinol oxidase, subunit 2:ATPase related to the helicase subunit of the Holliday junction resolvase:Uncharacterized protein conserved in bacteria:Predicted ATPase:Predicted membrane protein:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Metabolic pathways:Two-component system:Protein export:Bacterial secretion system:Nucleotide excision repair:Mismatch repair:General function prediction only:Function unknown:Signal transduction mechanisms:cydB:TIGR00365:FtsH_fam:tatAE:hyp_HI0043:Defense mechanisms:Information storage and processing:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking:Protein fate:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism:Energy Metabolism:Poorly characterized:Cellular processes and signaling" 238 "Energy production and conversion:Nicotinate-nucleotide pyrophosphorylase:NAD synthase:Predicted ATPase with chaperone activity:Demethylmenaquinone methyltransferase:5,10-methylenetetrahydrofolate reductase:Heme/copper-type cytochrome/quinol oxidases, subunit 1:Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain:Glycosyltransferases, probably involved in cell wall biogenesis:DNA replication protein:Pirin-related protein:ATP-dependent DNA ligase:Site-specific recombinases, DNA invertase Pin homologs:Cytochrome P450:Uncharacterized protein conserved in bacteria:Transcriptional activator of acetoin/glycerol metabolism:Cellobiose phosphorylase:Uncharacterized conserved protein:Predicted transcriptional regulator:Site-specific recombinase XerD:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Bisphenol degradation:Polycyclic aromatic hydrocarbon degradation:Aminobenzoate degradation:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Base excision repair:Nucleotide excision repair:Mismatch repair:Non-homologous end-joining:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:cinA_cterm:TIGR00368:CtaD_CoxA:Electron transport:Energy metabolism:Metabolism:Global:Metabolism:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Poorly characterized:Energy Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:DNA replication, recombination, and repair:DNA metabolism" 239 "Energy production and conversion:7-keto-8-aminopelargonate synthetase and related enzymes:Glutamate dehydrogenase/leucine dehydrogenase:Lactoylglutathione lyase and related lyases:Gamma-glutamyltransferase:Zn-dependent hydrolases, including glyoxylases:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Transcriptional regulator:Uncharacterized protein required for formate dehydrogenase activity:NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit:NADH:ubiquinone oxidoreductase 24 kD subunit:Malate synthase:Siderophore-interacting protein:Formyltetrahydrofolate synthetase:Uncharacterized anaerobic dehydrogenase:ABC-type oligopeptide transport system, periplasmic component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Arginine and proline metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:D-Glutamine and D-glutamate metabolism:Glutathione metabolism:Arachidonic acid metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Signal transduction mechanisms:g_glut_trans:fdhD_narQ:malate_syn_G:Fdh-alpha:crot-CoA-red:2am3keto_CoA:GSH_gloB:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Energy metabolism:Amino acids and amines:Electron transport:TCA cycle:Cellular processes:Detoxification:Biosynthesis of cofactors, prosthetic groups, and carriers:Glutathione and analogs:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins" 240 "Energy production and conversion:tRNA-dihydrouridine synthase:Argininosuccinate lyase:Exopolyphosphatase:Glutamate 5-kinase:Aspartate/tyrosine/aromatic aminotransferase:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Phosphopantetheine adenylyltransferase:3-dehydroquinate dehydratase II:Lipid A disaccharide synthetase:Transcription termination factor:Transcription elongation factor:NAD(FAD)-utilizing enzyme possibly involved in translation:Sortase and related acyltransferases:FOG: WD40-like repeat:Molybdopterin converting factor, small subunit:Cytochrome c, mono- and diheme variants:Small protein A (tmRNA-binding):Predicted acetyltransferase:ABC-type uncharacterized transport system, auxiliary component:Signal transduction protein containing GAF and PtsI domains:Cytochrome c556:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Arginine and proline metabolism:Tyrosine metabolism:Phenylalanine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Phosphonate and phosphinate metabolism:Lipopolysaccharide biosynthesis:Carbon fixation in photosynthetic organisms:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Phosphotransferase system (PTS):RNA degradation:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:cyt_tran_rel:gid_trmFO:lpxB:nifR3_yhdG:argH:proB:aroQ:PTS_I_fam:greA:moaD:nusB:Poorly characterized:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Transcription:Transcription factors:Protein synthesis:tRNA and rRNA base modification:Unknown function:General:Amino acid biosynthesis:Aromatic amino acid family:Glutamate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Molybdopterin:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 241 "Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:ABC-type Co2+ transport system, periplasmic component:Carbohydrate transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:gp16_SPP1:Membrane Transport:Prophage functions:Metabolism:Poorly characterized:Environmental Information Processing:Mobile and extrachromosomal element functions" 242 "Chromatin structure and dynamics:Energy production and conversion:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Dihydroxyacid dehydratase/phosphogluconate dehydratase:FAD/FMN-containing dehydrogenases:Phosphopantothenoylcysteine synthetase/decarboxylase:NTP pyrophosphohydrolases including oxidative damage repair enzymes:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:Cytochrome c biogenesis protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Threonine dehydrogenase and related Zn-dependent dehydrogenases:DnaJ-domain-containing proteins 1:Predicted membrane protein:Flagellar biosynthesis pathway, component FlhB:Transcriptional regulators:NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding:Putative hemolysin:Uncharacterized protein conserved in bacteria:Murein endopeptidase:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Butanoate metabolism:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:coaBC_dfp:yihY_not_rbn:PHB_DH:Intracellular trafficking, secretion, and vesicular transport:Carbohydrate Metabolism:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Lipid Metabolism:Unknown function" 243 "" 244 "Energy production and conversion:Dihydroorotate dehydrogenase:Nucleotidyltransferase/DNA polymerase involved in DNA repair:Uncharacterized flavoproteins:Uncharacterized NAD(FAD)-dependent dehydrogenases:Serine/threonine protein kinase:Ferredoxin:ABC-type cobalt transport system, ATPase component:ABC-type transport system involved in resistance to organic solvents, ATPase component:Membrane-associated lipoprotein involved in thiamine biosynthesis:DNA repair photolyase:L-serine deaminase:Ni,Fe-hydrogenase I cytochrome b subunit:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Nitrogen fixation protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:sda_mono:pyrD_sub1_fam:CytB-hydogenase:nifT_nitrog:Energy Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Glycolysis/gluconeogenesis:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Poorly characterized" 245 "Energy production and conversion:Hydrogenase maturation factor:Hydrogenase maturation factor:Site-specific DNA methylase:Zn finger protein HypA/HybF (possibly regulating hydrogenase expression):Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase:Hydrogenase maturation factor:Glutathione S-transferase:Ni,Fe-hydrogenase maturation factor:ABC-type dipeptide transport system, periplasmic component:Rubredoxin:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Predicted acetamidase/formamidase:Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain:Flp pilus assembly protein TadD, contains TPR repeats:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Arginine and proline metabolism:Phenylalanine metabolism:Tryptophan metabolism:Cyanoamino acid metabolism:Glutathione metabolism:Aminobenzoate degradation:Styrene degradation:Microbial metabolism in diverse environments:ABC transporters:Mismatch repair:General function prediction only:Signal transduction mechanisms:hydrog_prot:hypB:hypC_hupF:hypD:hypA:sensory_box:hypE:hydrog_HybE:Intracellular trafficking, secretion, and vesicular transport:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Metabolism:Amino Acid Metabolism:Poorly characterized:Cellular processes and signaling:Information storage and processing:Protein modification and repair:Protein fate" 246 "Short-chain dehydrogenases of various substrate specificities:Glycosyltransferase:Predicted permease:Predicted dehydrogenases and related proteins:Methyl-accepting chemotaxis protein:Sugar phosphate isomerases/epimerases:Phosphomannomutase:Flagellar hook-associated protein:Flagellar motor protein:Multidrug resistance efflux pump:Flagellar basal-body P-ring protein:Flagellar hook protein FlgE:Uncharacterized enzyme involved in inositol metabolism:Acetolactate synthase:ABC-type protease/lipase transport system, ATPase and permease components:P2-like prophage tail protein X:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Fructose and mannose metabolism:Amino sugar and nucleotide sugar metabolism:Inositol phosphate metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Bacterial chemotaxis:Flagellar assembly:General function prediction only:Signal transduction mechanisms:type_I_sec_PrtD:type_I_hlyD:flgK_ends:FlgEFG_subfam:Defense mechanisms:Chemotaxis and motility:Cellular processes:Protein and peptide secretion and trafficking:Protein fate:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Carbohydrate Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 247 "Predicted esterase:ABC-type multidrug transport system, ATPase and permease components:Transcriptional regulator:Multidrug resistance efflux pump:Permeases of the major facilitator superfamily:Bacteriophage protein gp37:Transcription:ABC transporters:General function prediction only:Function unknown:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Membrane Transport:Poorly characterized:Environmental Information Processing" 248 "Aspartyl-tRNA synthetase:Thymidylate synthase:Ribosomal protein L28:Dihydrofolate reductase:DNA primase (bacterial type):Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:Predicted phosphatases:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:2-methylthioadenine synthetase:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Predicted phosphatase/phosphohexomutase:Glycine/D-amino acid oxidases (deaminating):dUTPase:N-acetylmuramoyl-L-alanine amidase:16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases:Uncharacterized conserved protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Long-chain fatty acid transport protein:N-acyl-D-glucosamine 2-epimerase:Membrane carboxypeptidase/penicillin-binding protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pyrimidine metabolism:Arginine and proline metabolism:Peptidoglycan biosynthesis:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Carbon fixation in photosynthetic organisms:Folate biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Ribosome:RNA polymerase:DNA replication:General function prediction only:Function unknown:L28:TIGR00089:TIGR00093:aspS_bact:dut:dnaG:PGP_bact:HAD-SF-IA-v3:AcOrn-deacetyl:PBP_1a_fam:RpoD_Cterm:thym_sym:Cellular processes and signaling:Metabolism:Poorly characterized:DNA metabolism:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Sugars:Energy metabolism:Metabolism:Global:Metabolism:Replication and Repair:Translation:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:DNA replication, recombination, and repair:Carbohydrate Metabolism:Transcription:Transcription factors:Protein synthesis:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:tRNA and rRNA base modification:Unknown function:Enzymes of unknown specificity:Amino acid biosynthesis:Glutamate family:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing" 249 "Predicted glutathione S-transferase:Serine/threonine protein kinase:Transcriptional regulator:Uncharacterized membrane-associated protein:ATPase components of various ABC-type transport systems, contain duplicated ATPase:ABC-type transport system involved in resistance to organic solvents, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Glycosyltransferases, probably involved in cell wall biogenesis:Transglutaminase-like enzymes, putative cysteine proteases:Uncharacterized protein conserved in bacteria:FOG: GGDEF domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein involved in response to NO:Predicted membrane protein:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Metabolic pathways:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:cas3_core:Mobile and extrachromosomal element functions:Metabolism:Global:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Other:Signal transduction:Other" 250 "Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Rhodanese-related sulfurtransferase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Cold shock proteins:Restriction endonuclease:Transcriptional regulators:SufE protein probably involved in Fe-S center assembly:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Uncharacterized conserved protein:Predicted lactoylglutathione lyase:Uncharacterized conserved protein, contains double-stranded beta-helix domain:Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain:Uncharacterized protein conserved in bacteria:Usg protein, probable subunit of phosphoribosylanthranilate isomerase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Inorganic ion transport and metabolism:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:PHA_reg_PhaR:Defense mechanisms:Cellular processes and signaling:Information storage and processing:DNA interactions:Regulatory functions:Signal Transduction:Environmental Information Processing:Poorly characterized:Metabolism" 251 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Short-chain dehydrogenases of various substrate specificities:Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Methyl-accepting chemotaxis protein:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:Ribulose kinase:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Transcriptional regulators:Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain:Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain:Predicted membrane protein:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type xylose transport system, periplasmic component:ABC-type xylose transport system, permease component:Short-chain alcohol dehydrogenase of unknown specificity:Delta 1-pyrroline-5-carboxylate dehydrogenase:Site-specific recombinase XerD:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Pentose and glucuronate interconversions:Oxidative phosphorylation:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Toluene degradation:Glyoxylate and dicarboxylate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial chemotaxis:General function prediction only:Function unknown:Signal transduction mechanisms:dhsB:ttdA_fumA_fumB:D1pyr5carbox3:5C_CHO_kinase:succ_dehyd_cytB:Energy metabolism:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Metabolism:Amino acids and amines:TCA cycle:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 252 "Flagellar biosynthesis/type III secretory pathway ATPase:DNA-directed RNA polymerase specialized sigma subunit:Flagellar hook-associated protein:Flagellar basal body P-ring biosynthesis protein:Flagellar biosynthesis/type III secretory pathway protein:Flagellin and related hook-associated proteins:Flagellar biosynthesis pathway, component FlhB:Flagellar motor switch protein:Flagellar hook-basal body protein:Flagellar biosynthesis pathway, component FliR:Flagellar biosynthesis/type III secretory pathway lipoprotein:Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains:Type III secretory pathway, component EscS:Transcription:Cell motility:Posttranslational modification, protein turnover, chaperones:Two-component system:Bacterial chemotaxis:Flagellar assembly:RNA polymerase:Signal transduction mechanisms:fliE:fliF:fliG:flhB:fliI_yscN:fliR:fliQ:FliA_WhiG:fliN:flgK_ends:flagell_flgL:flgA_cterm:Intracellular trafficking, secretion, and vesicular transport:Transcription:ATP-proton motive force interconversion:Cellular processes:Chemotaxis and motility:Information storage and processing:Cellular processes and signaling:Genetic Information Processing:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Energy metabolism" 253 "Energy production and conversion:Molecular chaperone (small heat shock protein):Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase:Thiamine monophosphate synthase:Ni,Fe-hydrogenase I large subunit:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type Fe3+-siderophore transport system, permease component:MoxR-like ATPases:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type sulfate/molybdate transport systems, ATPase component:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Predicted metal-dependent hydrolase with the TIM-barrel fold:Ni,Fe-hydrogenase I small subunit:Transcriptional regulators:Methylmalonyl-CoA mutase, N-terminal domain/subunit:Hydroxyethylthiazole kinase, sugar kinase family:Pyridoxal/pyridoxine/pyridoxamine kinase:Uncharacterized protein conserved in bacteria:Hydrogenase/urease accessory protein:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Glyoxylate and dicarboxylate metabolism:Nitrotoluene degradation:Thiamine metabolism:Vitamin B6 metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:HMP-P_kinase:hydA:acid_CoA_mut_C:pyridox_kin:thiE:thiM:kduD:degP_htrA_DO:Degradation of proteins, peptides, and glycopeptides:Protein fate:Biosynthesis and degradation of polysaccharides:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Thiamine:Pyridoxine:Biosynthesis of cofactors, prosthetic groups, and carriers" 254 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Oligoendopeptidase F:Putative effector of murein hydrolase:Putative effector of murein hydrolase LrgA:Transcriptional regulators:V8-like Glu-specific endopeptidase:Predicted membrane protein:Amino acid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Peptidoglycan biosynthesis:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:General function prediction only:Function unknown:mono_pep_trsgly:M3_fam_3:Metabolism:Carbohydrate Metabolism:Glycan Biosynthesis and Metabolism:Global:Metabolism:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 255 "Energy production and conversion:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Uncharacterized conserved protein:ABC-type transport system involved in Fe-S cluster assembly, ATPase component:Selenocysteine lyase:Sugar kinases, ribokinase family:Isocitrate dehydrogenases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type sugar transport system, ATPase component:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:ABC-type sugar transport system, periplasmic component:Uncharacterized conserved protein:Predicted ABC-type sugar transport system, permease component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Posttranslational modification, protein turnover, chaperones:Citrate cycle (TCA cycle):Fructose and mannose metabolism:Selenocompound metabolism:Glutathione metabolism:Carbon fixation pathways in prokaryotes:Thiamine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:nadp_idh_euk:sufC:sufS:Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Poorly characterized:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:TCA cycle:Energy metabolism:Metabolism:Global" 256 "Aminopeptidase N:Cobalamin-5-phosphate synthase:Dihydroorotase:UDP-N-acetylmuramoylalanine-D-glutamate ligase:Exonuclease VII, large subunit:Uncharacterized host factor I protein:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase):Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pyrimidine metabolism:D-Glutamine and D-glutamate metabolism:Glutathione metabolism:Peptidoglycan biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:Two-component system:RNA degradation:Mismatch repair:General function prediction only:Signal transduction mechanisms:xseA:cobS:pyrC_dimer:murD:CobT:Hfq:pepN_proteo:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Signal Transduction:Environmental Information Processing:Metabolism:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Nucleotide Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesis:Regulatory functions:Other:DNA metabolism:Degradation of DNA:Protein fate:Degradation of proteins, peptides, and glycopeptides" 257 "Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis:Cell wall/membrane/envelope biogenesis:Aminoacyl-tRNA biosynthesis:Ribosome:TIGR00006:PQQ_syn_pqqA:Cellular processes and signaling:Biosynthesis of cofactors, prosthetic groups, and carriers:Translation:Genetic Information Processing:Other:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan" 258 "Energy production and conversion:Glutamyl- and glutaminyl-tRNA synthetases:Dihydroorotase and related cyclic amidohydrolases:Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain:Isoleucyl-tRNA synthetase:Adenylosuccinate synthase:Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase:Histidyl-tRNA synthetase:Xanthosine triphosphate pyrophosphatase:Phosphoribosylaminoimidazole (AIR) synthetase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Tyrosyl-tRNA synthetase:Guanylate kinase:Putative translation initiation inhibitor, yjgF family:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Queuine/archaeosine tRNA-ribosyltransferase:Prolyl-tRNA synthetase:Isocitrate/isopropylmalate dehydrogenase:Carbamoylphosphate synthase small subunit:IMP dehydrogenase/GMP reductase:GMP synthase, PP-ATPase domain/subunit:Phosphoserine phosphatase:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:RNase PH:Glycyl-tRNA synthetase, beta subunit:Glycyl-tRNA synthetase, alpha subunit:Glucokinase:Uncharacterized stress-induced protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Galactose metabolism:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Histidine metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Methane metabolism:Thiamine metabolism:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:TIGR00007:TIGR00042:gatA:leuB:purA:glyS:tyrS:TIGR00255:serB:glyQ:ileS:Q_tRNA_tgt:hisS:gltX_bact:pyrC_multi:purM:guaA_Cterm:IMP_dehydrog:CPSaseIIsmall:FGAM_synth_II:RNasePH:guanyl_kin:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Purine ribonucleotide biosynthesis:Pyrimidine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:RNA processing:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Hypothetical proteins:Conserved:Amino acid biosynthesis:Pyruvate family:Serine family:Histidine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Translation" 259 "Glutamine synthetase:Deoxyribose-phosphate aldolase:Transcriptional regulator:Signal transduction histidine kinase:Glycine/D-amino acid oxidases (deaminating):Outer membrane protein:Predicted thioesterase:ADP-ribose pyrophosphatase:ABC-type sugar transport system, ATPase component:Glycosyltransferases, probably involved in cell wall biogenesis:Transcriptional regulator:Transcriptional regulators of sugar metabolism:Beta-glucosidase-related glycosidases:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Signal transduction histidine kinase regulating citrate/malate metabolism:Endoglucanase Y:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Pentose phosphate pathway:Alanine aspartate and glutamate metabolism:Arginine and proline metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:deoC:sensory_box:CelA:Information storage and processing:Small molecule interactions:Regulatory functions:Other:Energy metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Metabolism:Signal Transduction:Environmental Information Processing:Amino Acid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 260 "Energy production and conversion:Geranylgeranyl pyrophosphate synthase:7-keto-8-aminopelargonate synthetase and related enzymes:4-hydroxybenzoate polyprenyltransferase and related prenyltransferases:Dehydrogenases (flavoproteins):Fe-S oxidoreductase:Phytoene dehydrogenase and related proteins:Mg-chelatase subunit ChlI:Mg-chelatase subunit ChlD:Nitrogenase subunit NifH (ATPase):Isopentenyldiphosphate isomerase:Phytoene/squalene synthetase:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Coenzyme transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Carotenoid biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:chlor_syn_BchG:5aminolev_synth:BchX:BchJ:BchF:BchM-ChlM:BchP-ChlP:BchE:BchI-ChlI:BchD-ChlD:IPP_isom_1:crtI_fam:Metabolism of Cofactors and Vitamins:Energy metabolism:Amino Acid Metabolism:Photosynthesis:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Heme, porphyrin, and cobalamin:Chlorophyll and bacteriochlorphyll:Metabolism:Metabolism:Metabolism:Global:Metabolism of Terpenoids and Polyketides" 261 "Energy production and conversion:Glucan phosphorylase:Ketol-acid reductoisomerase:Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase:1-acyl-sn-glycerol-3-phosphate acyltransferase:Cell division GTPase:Stress-induced morphogen (activity unknown):Acetyl-CoA hydrolase:Single-stranded DNA-binding protein:MoxR-like ATPases:Membrane proteins related to metalloendopeptidases:Integral membrane protein CcmA involved in cell shape determination:Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component:Uncharacterized protein conserved in bacteria:Cell division protein:Predicted ATPase involved in cell division:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Purine metabolism:Valine leucine and isoleucine biosynthesis:Starch and sucrose metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Pantothenate and CoA biosynthesis:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:ftsZ:TIGR00302:ilvC:ssb:PD_CobS:P_ylase:MJ0042_CXXC:YgfH_subfam:Cellular processes and signaling:Carbohydrate Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Biosynthesis and degradation of polysaccharides:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Cellular processes:Cell division:Amino acid biosynthesis:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 262 "Energy production and conversion:Exopolyphosphatase:(acyl-carrier-protein) S-malonyltransferase:Lactoylglutathione lyase and related lyases:Exoribonuclease R:Predicted Zn-dependent peptidases:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Uncharacterized membrane protein (homolog of Drosophila rhomboid):Periplasmic protease:NAD-dependent aldehyde dehydrogenases:Cytochrome c biogenesis factor:ABC-type spermidine/putrescine transport system, permease component I:Uncharacterized protein conserved in bacteria:Protein-disulfide isomerase:Beta-glucanase/Beta-glucan synthetase:Protein-L-isoaspartate carboxylmethyltransferase:Arabinose efflux permease:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Membrane-bound lytic murein transglycosylase B:Lipid A core - O-antigen ligase and related enzymes:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:N-formylglutamate amidohydrolase:Uncharacterized protein conserved in bacteria:Predicted secreted (periplasmic) protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Purine metabolism:Valine leucine and isoleucine degradation:Arginine and proline metabolism:Inositol phosphate metabolism:Propanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:RNA degradation:General function prediction only:Function unknown:Signal transduction mechanisms:fabD:prc:nrfE:3_prime_RNase:TIGR01244:MMSDH:AcOrn-deacetyl:MltB_2:Pal_lipo:Glutamate family:Amino acid biosynthesis:Conserved:Hypothetical proteins:Protein modification and repair:Protein fate:Degradation of RNA:Transcription:Biosynthesis:Fatty acid and phospholipid metabolism:Electron transport:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of murein sacculus and peptidoglycan:Cell envelope" 263 "Prephenate dehydratase:Guanylate kinase:Phosphate/sulphate permeases:3-oxoacyl-[acyl-carrier-protein] synthase III:ABC-type branched-chain amino acid transport systems, ATPase component:ABC-type branched-chain amino acid transport systems, ATPase component:Fatty acid/phospholipid biosynthesis enzyme:Nucleotide-binding protein implicated in inhibition of septum formation:Carbamoylphosphate synthase small subunit:Branched-chain amino acid ABC-type transport system, permease components:rRNA methylase:dsRNA-specific ribonuclease:Transcriptional regulator:Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily:ABC-type branched-chain amino acid transport systems, periplasmic component:ABC-type metal ion transport system, ATPase component:ABC-type metal ion transport system, periplasmic component/surface antigen:Ribonucleases G and E:Uncharacterized stress-induced protein:Predicted Rossmann fold nucleotide-binding protein:Citrate lyase beta subunit:Uncharacterized protein conserved in bacteria:ABC-type branched-chain amino acid transport system, permease component:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glycerolipid metabolism:Glycerophospholipid metabolism:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:rRNA_methyl_1:maf:plsX:TIGR00255:TIGR00363:TIGR00730:fabH:CPSaseIIsmall:RNaseIII:guanyl_kin:Cell division:Carbohydrate Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Pyrimidine ribonucleotide biosynthesis:Transcription:RNA processing:Protein synthesis:tRNA and rRNA base modification:Cellular processes:Metabolism:Hypothetical proteins:Conserved:Cell envelope:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 264 "Energy production and conversion:Pentose-5-phosphate-3-epimerase:Fructose/tagatose bisphosphate aldolase:Short-chain dehydrogenases of various substrate specificities:Predicted phosphatases:Predicted phosphatase/phosphohexomutase:Multidrug resistance efflux pump:Beta-lactamase class C and other penicillin binding proteins:Transcriptional regulators:Ribulose 1,5-bisphosphate carboxylase, large subunit:Cytochrome b:Cytochrome c556:Ribulose bisphosphate carboxylase small subunit:Carbohydrate transport and metabolism:Transcription:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Carbon fixation in photosynthetic organisms:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:cbbA:efflux_EmrB:rpe:PGP_bact:HAD-SF-IA-v3:cbbX_cfxQ:Defense mechanisms:Glycolysis/gluconeogenesis:Energy metabolism:Metabolism:Metabolism:Global:Energy Metabolism:Pentose phosphate pathway:Carbohydrate Metabolism:Sugars:Transport and binding proteins:Other:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 265 "Energy production and conversion:Ni,Fe-hydrogenase I large subunit:Phosphopantetheinyl transferase (holo-ACP synthase):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:2-keto-3-deoxy-6-phosphogluconate aldolase:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Inactive homolog of metal-dependent proteases, putative molecular chaperone:Transcriptional regulators:Arabinose efflux permease:Arylsulfatase A and related enzymes:Uncharacterized conserved protein:ABC-type sugar transport systems, ATPase components:Inactivated superfamily I helicase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Galactose metabolism:Glycine serine and threonine metabolism:Pantothenate and CoA biosynthesis:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:acpS:addB_alphas:chol_sulfatase:bact_YeaZ:Carbohydrate Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:DNA metabolism:Biosynthesis:Fatty acid and phospholipid metabolism:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:DNA replication, recombination, and repair" 266 "Energy production and conversion:Periplasmic serine proteases (ClpP class):Dehydrogenases (flavoproteins):Predicted transcriptional regulators:ABC-type metal ion transport system, periplasmic component/surface adhesin:Predicted Fe-S-cluster redox enzyme:ABC-type Mn2+/Zn2+ transport systems, permease components:ABC-type Mn/Zn transport systems, ATPase component:Acyl-CoA dehydrogenases:Electron transfer flavoprotein, alpha subunit:Precorrin isomerase:Electron transfer flavoprotein, beta subunit:Bacteriophage head-tail adaptor:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Geraniol degradation:Naphthalene degradation:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:TIGR00048:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Protein synthesis:tRNA and rRNA base modification:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 267 "Dimethyladenosine transferase (rRNA methylation):Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Dephospho-CoA kinase:(acyl-carrier-protein) S-malonyltransferase:Nucleoside-diphosphate-sugar epimerases:Acetyltransferases:ABC-type antimicrobial peptide transport system, permease component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Phosphopantetheinyl transferase (holo-ACP synthase):Cell division protein FtsI/penicillin-binding protein 2:2-keto-3-deoxy-6-phosphogluconate aldolase:DNA polymerase III, epsilon subunit and related 3'-5' exonucleases:ATPase components of various ABC-type transport systems, contain duplicated ATPase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Hemolysins and related proteins containing CBS domains:Flagellar motor protein:Uncharacterized protein conserved in bacteria:Protein involved in catabolism of external DNA:Uncharacterized conserved protein:ABC-type spermidine/putrescine transport systems, ATPase components:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Galactose metabolism:Purine metabolism:Pyrimidine metabolism:Peptidoglycan biosynthesis:Pantothenate and CoA biosynthesis:Metabolic pathways:ABC transporters:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:TIGR00152:acpS:dnaq:ksgA:parE_Gneg:pbp2_mrdA:Defense mechanisms:Biosynthesis and degradation of murein sacculus and peptidoglycan:Carbohydrate Metabolism:Nucleotide Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:Degradation of DNA:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Cell envelope:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 268 "Glutamine phosphoribosylpyrophosphate amidotransferase:ATP phosphoribosyltransferase:Acetyltransferase (isoleucine patch superfamily):Anthranilate/para-aminobenzoate synthases component I:FAD synthase:Dihydrodipicolinate reductase:Superfamily II DNA and RNA helicases:K+ transport systems, NAD-binding component:Predicted Zn-dependent peptidases:Exonuclease III:Formyltetrahydrofolate hydrolase:Predicted Fe-S-cluster redox enzyme:Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase:Na+/H+ antiporter NhaD and related arsenite permeases:Organic solvent tolerance protein OstA:Acetyltransferases, including N-acetylases of ribosomal proteins:Transcriptional regulators:Uncharacterized protein conserved in bacteria:ATP phosphoribosyltransferase involved in histidine biosynthesis:Invasion protein B, involved in pathogenesis:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Alanine aspartate and glutamate metabolism:Lysine biosynthesis:Histidine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Lipopolysaccharide biosynthesis:Glyoxylate and dicarboxylate metabolism:One carbon pool by folate:Riboflavin metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:RNA degradation:Base excision repair:General function prediction only:Function unknown:dapB:TIGR00048:hisG:ribF:trpE_most:xth:PurU:purF:lipid_A_lpxA:Poorly characterized:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA and rRNA base modification:Amino acid biosynthesis:Aromatic amino acid family:Aspartate family:Histidine family:Biosynthesis of cofactors, prosthetic groups, and carriers:Riboflavin, FMN, and FAD:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 269 "Energy production and conversion:NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases:Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit:NADH:ubiquinone oxidoreductase 49 kD subunit 7:NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K):NADH:ubiquinone oxidoreductase subunit 3 (chain A):NADH:ubiquinone oxidoreductase subunit 6 (chain J):NADH:ubiquinone oxidoreductase 27 kD subunit:NADH:ubiquinone oxidoreductase subunit 1 (chain H):NADH:ubiquinone oxidoreductase subunit 2 (chain N):NADH:ubiquinone oxidoreductase subunit 4 (chain M):NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G):Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I):NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit:NADH:ubiquinone oxidoreductase 24 kD subunit:Inorganic ion transport and metabolism:Oxidative phosphorylation:Benzoate degradation:Metabolic pathways:Microbial metabolism in diverse environments:Function unknown:NDH_I_N:nuoB_fam:nuoE_fam:nuoF_fam:NuoC_fam:NuoD:NuoI:NDH_I_M:NuoG:NDH_I_L:Energy metabolism:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Poorly characterized:Energy Metabolism:Metabolism:Electron transport" 270 "Energy production and conversion:Phosphotransacetylase:Acetate kinase:Polyferredoxin:Enoyl-[acyl-carrier-protein] reductase (NADH):Cytochrome c, mono- and diheme variants:Cation transport ATPase:Outer membrane protein:Cbb3-type cytochrome oxidase, cytochrome c subunit:Outer membrane protein W:Uncharacterized protein, possibly involved in nitrogen fixation:Poly(3-hydroxyalkanoate) synthetase:Cbb3-type cytochrome oxidase, subunit 1:Cbb3-type cytochrome oxidase, subunit 3:Predicted integral membrane protein linked to a cation pump:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Oxidative phosphorylation:Taurine and hypotaurine metabolism:Pyruvate metabolism:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Microbial metabolism in diverse environments:ackA:ccoN:ccoO:ccoP:ccoS:ATPase_P-type:ccoG_rdxA_fixG:Cellular processes and signaling:Protein modification and repair:Metabolism:Global:Metabolism:Metabolism of Other Amino Acids:Lipid Metabolism:Protein fate:Fermentation:Energy Metabolism:Electron transport:Energy metabolism:Metabolism:Carbohydrate Metabolism" 271 "Energy production and conversion:Diaminopimelate decarboxylase:Glutamate synthase domain 2:Prephenate dehydratase:Ribonucleotide reductase, alpha subunit:Protein chain release factor A:Cytidylate kinase:Sugar kinases, ribokinase family:Aspartokinases:rRNA methylase:2-methylthioadenine synthetase:Predicted phosphatase/phosphohexomutase:N6-adenine-specific methylase:Predicted GTPases:Predicted membrane GTPase involved in stress response:Predicted Rossmann fold nucleotide-binding protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Saccharopine dehydrogenase and related proteins:ATP sulfurylase (sulfate adenylyltransferase):Uncharacterized conserved protein:Cytochrome c2:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Inorganic ion transport and metabolism:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Bisphenol degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Selenocompound metabolism:Polycyclic aromatic hydrocarbon degradation:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Nitrogen metabolism:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:Signal transduction mechanisms:prfB:rRNA_methyl_1:TIGR00089:TIGR00095:small_GTP:sopT:asp_kin_monofn:TIGR00730:nspC:HAD-SF-IA-v3:NrdJ_Z:Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Polyamine biosynthesis:Carbohydrate Metabolism:Sulfur metabolism:Purines, pyrimidines, nucleosides, and nucleotides:2'-Deoxyribonucleotide metabolism:Protein synthesis:tRNA and rRNA base modification:Translation factors:Hypothetical proteins:Conserved:Unknown function:Enzymes of unknown specificity:General:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Central intermediary metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism" 272 "Ribosomal protein S7:Ribosomal protein S10:Ribosomal protein L3:Ribosomal protein L4:Ribosomal protein L2:Ribosomal protein L22:Ribosomal protein S3:Ribosomal protein L14:Ribosomal protein L5:Ribosomal protein S8:Ribosomal protein L6P/L9E:Ribosomal protein S5:Ribosomal protein S19:Ribosomal protein L24:Ribosomal protein S14:Ribosomal protein L18:Translation elongation factors (GTPases):Translation, ribosomal structure and biogenesis:Ribosome:L18_bact:small_GTP:rpsC_bact:rpsE_bact:rpsG_bact:rplV_bact:rpsJ_bact:rpsS_bact:rplN_bact:rplX_bact:rplB_bact:L3_bact:L6_bact:rplD_bact:General:Translation:Protein synthesis:Ribosomal proteins: synthesis and modification:Unknown function:Genetic Information Processing:Information storage and processing" 273 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase:GMP synthase - Glutamine amidotransferase domain:Transcriptional regulator:Alanine dehydrogenase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):NADH dehydrogenase, FAD-containing subunit:Ca2+-binding protein (EF-Hand superfamily):Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Fatty acid biosynthesis:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine biosynthesis:Taurine and hypotaurine metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Pantothenate and CoA biosynthesis:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Base excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:alaDH:Nterm_to_SelD:Cytoskeleton:Amino acids and amines:Carbohydrate Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Global:Metabolism:Energy metabolism:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 274 "Energy production and conversion:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Coproporphyrinogen III oxidase:Glycosyltransferase:FOG: CBS domain:Sugar kinases, ribokinase family:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Lactate dehydrogenase and related dehydrogenases:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Cold shock proteins:Uncharacterized conserved protein:Predicted transcriptional regulators:ABC-type sugar transport system, periplasmic component:Cytochrome c, mono- and diheme variants:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Cytochrome c556:Delta 1-pyrroline-5-carboxylate dehydrogenase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid biosynthesis:Fatty acid metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Porphyrin and chlorophyll metabolism:Limonene and pinene degradation:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:D_ribokin_bact:Xenobiotics Biodegradation and Metabolism:Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Sugars:Energy metabolism:Metabolism:Global" 275 "Energy production and conversion:3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases:3-polyprenyl-4-hydroxybenzoate decarboxylase:Phosphotransacetylase:Transcriptional regulator:Enoyl-[acyl-carrier-protein] reductase (NADH):Coproporphyrinogen III oxidase and related Fe-S oxidoreductases:Collagenase and related proteases:DnaK suppressor protein:Cytochrome B561:Putative lipid carrier protein:Poly(3-hydroxyalkanoate) synthetase:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Fatty acid biosynthesis:Ubiquinone and other terpenoid-quinone biosynthesis:Alanine aspartate and glutamate metabolism:beta-Alanine metabolism:Taurine and hypotaurine metabolism:Pyruvate metabolism:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Signal transduction mechanisms:TIGR00148:ubiX_pad:hemN:Information storage and processing:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Global:Metabolism:Unknown function:Enzymes of unknown specificity:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Metabolism:Cellular processes and signaling:Metabolism" 276 "Transcriptional regulator:Flp pilus assembly protein CpaB:Flp pilus assembly protein TadG:Flp pilus assembly protein, ATPase CpaF:Flp pilus assembly protein, ATPase CpaE:Flp pilus assembly protein TadB:Transcription:pilus_cpaB:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing" 277 "3-isopropylmalate dehydratase small subunit:Phosphoribosyl-AMP cyclohydrolase:Folylpolyglutamate synthase:3-oxoacyl-(acyl-carrier-protein) synthase:Signal recognition particle GTPase:Preprotein translocase subunit SecA (ATPase, RNA helicase):Preprotein translocase subunit SecE:tmRNA-binding protein:Biopolymer transport proteins:Predicted metal-dependent hydrolase:Protein-disulfide isomerase:Transcriptional regulators:Membrane glycosyltransferase:Periplasmic glucans biosynthesis protein:Uncharacterized protein conserved in bacteria:ABC-type oligopeptide transport system, periplasmic component:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Valine leucine and isoleucine biosynthesis:Histidine metabolism:C5-Branched dibasic acid metabolism:Folate biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Protein export:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:smpB:leuD:ffh:secA:secE_bact:folC:FYDLN_acid:tolQ:fabF:Intracellular trafficking, secretion, and vesicular transport:Protein synthesis:Biosynthesis:Fatty acid and phospholipid metabolism:Metabolism:Global:Metabolism:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Lipid Metabolism:Protein fate:Carbohydrate Metabolism:Protein and peptide secretion and trafficking:Cellular processes:Pathogenesis:Amino acid biosynthesis:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Folic acid:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Other" 278 "Energy production and conversion:Triosephosphate isomerase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Glutamate dehydrogenase/leucine dehydrogenase:Lactoylglutathione lyase and related lyases:Gamma-glutamyltransferase:Panthothenate synthetase:Glycosyltransferase:ATPases involved in chromosome partitioning:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:Glycine/D-amino acid oxidases (deaminating):Predicted oxidoreductases (related to aryl-alcohol dehydrogenases):Predicted dehydrogenases and related proteins:Enoyl-CoA hydratase/carnithine racemase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Zn-dependent alcohol dehydrogenases, class III:Sugar phosphate isomerases/epimerases:ABC-type sugar transport system, ATPase component:Outer membrane protein:Transcriptional regulators:ABC-type sugar transport system, periplasmic component:Protein-L-isoaspartate carboxylmethyltransferase:Predicted membrane protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fructose and mannose metabolism:Fatty acid metabolism:Synthesis and degradation of ketone bodies:Ubiquinone and other terpenoid-quinone biosynthesis:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Arginine and proline metabolism:Tyrosine metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:Taurine and hypotaurine metabolism:Selenocompound metabolism:Cyanoamino acid metabolism:D-Glutamine and D-glutamate metabolism:Glutathione metabolism:Inositol phosphate metabolism:Arachidonic acid metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Aminobenzoate degradation:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Carbon fixation in photosynthetic organisms:Pantothenate and CoA biosynthesis:Limonene and pinene degradation:Nitrogen metabolism:Caprolactam degradation:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Bacterial chemotaxis:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:panC:tim:TAT_signal_seq:type_I_sec_TolC:PHB_DH:Ubi-OHases:adh_III_F_hyde:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Membrane Transport:Environmental Information Processing:Metabolism:Cellular processes and signaling:Information storage and processing:Pantothenate and coenzyme A:Translation:Genetic Information Processing:Menaquinone and ubiquinone:Biosynthesis of cofactors, prosthetic groups, and carriers:Porins:Transport and binding proteins:Xenobiotics Biodegradation and Metabolism:Protein and peptide secretion and trafficking:Metabolism of Terpenoids and Polyketides:Protein fate:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Metabolism:Lipid Metabolism:Glycolysis/gluconeogenesis:Fermentation:Energy metabolism:Energy Metabolism:Global:Carbohydrate Metabolism:Cell Motility:Cellular Processes" 279 "Energy production and conversion:Riboflavin synthase beta-chain:3,4-dihydroxy-2-butanone 4-phosphate synthase:Transaldolase:N-formylmethionyl-tRNA deformylase:tRNA-(guanine-N1)-methyltransferase:Citrate synthase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Predicted GTPase:Isocitrate dehydrogenases:Phosphoserine phosphatase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Predicted sugar phosphatases of the HAD superfamily:tmRNA-binding protein:Selenophosphate synthase:ABC-type dipeptide transport system, periplasmic component:Aconitase A:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Lysyl-tRNA synthetase (class I):Metal-dependent amidase/aminoacylase/carboxypeptidase:3-deoxy-D-manno-octulosonic-acid transferase:Beta-lactamase class C and other penicillin binding proteins:Protein related to penicillin acylase:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Citrate cycle (TCA cycle):Pentose phosphate pathway:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Penicillin and cephalosporin biosynthesis:Phenylalanine metabolism:Selenocompound metabolism:Glutathione metabolism:Lipopolysaccharide biosynthesis:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Carbon fixation pathways in prokaryotes:Riboflavin metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Bacterial chemotaxis:General function prediction only:Function unknown:pept_deformyl:smpB:trmD:lumazine-synth:nadp_idh_euk:serB:mazG:lysS_arch:selD:ribB:fsa_talC_mipB:aconitase_1:HAD-SF-IIA-hyp4:cit_synth_I:amidohydrolases:Obg_CgtA:Defense mechanisms:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Biosynthesis of cofactors, prosthetic groups, and carriers:Serine family:Amino acid biosynthesis:General:Unknown function:Protein modification and repair:Degradation of proteins, peptides, and glycopeptides:Protein fate:tRNA and rRNA base modification:tRNA aminoacylation:Other:Protein synthesis:TCA cycle:Pentose phosphate pathway:Energy metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Riboflavin, FMN, and FAD:Carbohydrate Metabolism" 280 "Zn-dependent hydrolases, including glyoxylases:Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted unusual protein kinase:Glycine/D-amino acid oxidases (deaminating):Alanine dehydrogenase:Uncharacterized membrane protein (homolog of Drosophila rhomboid):Exonuclease III:MoxR-like ATPases:Predicted permeases:Phosphomannomutase:Predicted exonuclease of the beta-lactamase fold involved in RNA processing:Predicted membrane protein:Putative salt-induced outer membrane protein:Predicted membrane protein:Gluconolactonase:Predicted symporter:Predicted membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Alanine aspartate and glutamate metabolism:Phenylalanine metabolism:Taurine and hypotaurine metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Nitrogen metabolism:Metabolic pathways:Base excision repair:General function prediction only:Function unknown:exoDNase_III:alaDH:sss:glmM:GSH_gloB:Detoxification:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Replication and Repair:Global:Metabolism:Central intermediary metabolism:Amino sugars:Energy metabolism:Amino acids and amines:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Cations and iron carrying compounds:Cellular processes:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 281 "Aspartate/tyrosine/aromatic aminotransferase:Hypoxanthine-guanine phosphoribosyltransferase:3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:Methyl-accepting chemotaxis protein:Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase:ABC-type sugar transport systems, permease components:N-acetylglucosamine-6-phosphate deacetylase:Cytosine/uracil/thiamine/allantoin permeases:ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Fatty acid biosynthesis:Purine metabolism:Amino sugar and nucleotide sugar metabolism:Lipopolysaccharide biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Bacterial chemotaxis:Signal transduction mechanisms:nagA:HGPRTase:fabZ:lipid_A_lpxA:Defense mechanisms:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Carbohydrate Metabolism:Lipid Metabolism:Nucleotide Metabolism:Glycan Biosynthesis and Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Central intermediary metabolism:Amino sugars:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:Cell envelope:Metabolism:Cellular processes and signaling:Metabolism" 282 "Nucleotidyltransferase/DNA polymerase involved in DNA repair:Deoxyribodipyrimidine photolyase:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Predicted ATPase with chaperone activity:ABC-type dipeptide transport system, periplasmic component:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Glucose/sorbosone dehydrogenases:FOG: GGDEF domain:Phage protein D:ABC-type spermidine/putrescine transport systems, ATPase components:Proline racemase:Uncharacterized protein conserved in bacteria:P2-like prophage tail protein X:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Arginine and proline metabolism:Metabolic pathways:ABC transporters:Two-component system:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:TIGR00368:oligo_HPY:Metabolism:Amino Acid Metabolism:Genetic Information Processing:Transcription:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:General:Signal transduction:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 283 "Energy production and conversion:NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases:NADH:ubiquinone oxidoreductase 49 kD subunit 7:NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K):NADH:ubiquinone oxidoreductase subunit 3 (chain A):NADH:ubiquinone oxidoreductase subunit 6 (chain J):NADH:ubiquinone oxidoreductase subunit 1 (chain H):NADH:ubiquinone oxidoreductase subunit 2 (chain N):NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G):Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I):NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit:NADH:ubiquinone oxidoreductase 24 kD subunit:Inorganic ion transport and metabolism:Oxidative phosphorylation:Alanine aspartate and glutamate metabolism:beta-Alanine metabolism:Propanoate metabolism:Butanoate metabolism:Metabolic pathways:nuoB_fam:NuoD:NuoI:NuoG:Energy metabolism:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Global:Metabolism:Metabolism:Electron transport:Metabolism" 284 "Energy production and conversion:Transketolase:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Fructose-1,6-bisphosphatase:Fructose/tagatose bisphosphate aldolase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Ribulose 1,5-bisphosphate carboxylase, large subunit:Phosphoribulokinase:Ribulose bisphosphate carboxylase small subunit:Carbohydrate transport and metabolism:Lipid transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Carbon fixation in photosynthetic organisms:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:cbbA:tktlase_bact:GAPDH-I:Energy metabolism:Carbohydrate Metabolism:Energy Metabolism:Global:Metabolism:Metabolism:Glycolysis/gluconeogenesis:Pentose phosphate pathway:Metabolism:Poorly characterized" 285 "Energy production and conversion:Predicted flavoprotein:Zn-dependent hydrolases, including glyoxylases:Zn-dependent protease with chaperone function:Transcriptional regulator:Glutathione S-transferase:ABC-type branched-chain amino acid transport systems, periplasmic component:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Nitroreductase:FOG: CheY-like receiver:Adenine deaminase:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Transcriptional regulators:Transcriptional regulator/sugar kinase:4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase:Uncharacterized conserved protein:Transposase and inactivated derivatives:Uncharacterized protein conserved in bacteria:Bacterial lipocalin:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Site-specific recombinase XerC:Flp pilus assembly protein TadD, contains TPR repeats:Predicted cobalamin binding protein:Uncharacterized conserved small protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Glutathione metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:ispE:ahpD_dom:ade:BluB:resist_ArsH:Intracellular trafficking, secretion, and vesicular transport:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Detoxification:Cellular processes:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Metabolism:Cell Motility:Cellular Processes:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism of Terpenoids and Polyketides:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Nucleotide Metabolism:Carbohydrate Metabolism" 286 "Methionine aminopeptidase:Isopropylmalate/homocitrate/citramalate synthases:Zn-dependent hydrolases, including glyoxylases:Predicted transcriptional regulators:Biopolymer transport proteins:Biopolymer transport protein:Pyridoxal phosphate biosynthesis protein:Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA:ABC-type antimicrobial peptide transport system, ATPase component:Peroxiredoxin:DNA-binding HTH domain-containing proteins:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Vitamin B6 metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:met_pdase_I:pdxJ:leuA_bact:tolQ:tolR:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyruvate family:Amino acid biosynthesis:Pathogenesis:Cellular processes:Protein modification and repair:Protein fate:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Pyridoxine" 287 "Zn-dependent hydrolases, including glyoxylases:DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32):Predicted permease:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Parvulin-like peptidyl-prolyl isomerase:UDP-3-O-acyl-N-acetylglucosamine deacetylase:Uncharacterized conserved protein:Outer membrane lipoprotein-sorting protein:Uncharacterized secreted protein:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Lipopolysaccharide biosynthesis:Metabolic pathways:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:lpxC:rpoH_proteo:Cellular processes and signaling:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Transcription:Global:Metabolism:Transcription:Transcription factors:Cell envelope:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Metabolism:Poorly characterized" 288 "Trk-type K+ transport systems, membrane components:Predicted amidohydrolase:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Predicted permease:Spermidine/putrescine-binding periplasmic protein:Threonine dehydrogenase and related Zn-dependent dehydrogenases:ABC-type multidrug transport system, ATPase and permease components:Co/Zn/Cd efflux system component:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Predicted O-methyltransferase:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Bacteriophage protein gp37:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Amino acid transport and metabolism:Transcription:Inorganic ion transport and metabolism:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:CDF:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds:Transport and binding proteins:Signal Transduction:Membrane Transport:Environmental Information Processing:Poorly characterized:Metabolism" 289 "Energy production and conversion:Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:ATPases with chaperone activity, ATP-binding subunit:ABC-type transport system involved in Fe-S cluster assembly, permease component:Transcriptional regulator:Lysine 2,3-aminomutase:Predicted transcriptional regulator:Sugar phosphate permease:Predicted enzyme related to lactoylglutathione lyase:Predicted thiol oxidoreductase:Predicted periplasmic lipoprotein:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein, contains double-stranded beta-helix domain:2-hydroxychromene-2-carboxylate isomerase:Predicted alpha/beta hydrolase:Uncharacterized conserved protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Fructose and mannose metabolism:Lysine degradation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:TIGR00238:rrf2_super:sufB:degP_htrA_DO:ClpA:Biosynthesis of cofactors, prosthetic groups, and carriers:General:Unknown function:Degradation of proteins, peptides, and glycopeptides:Protein fate:Electron transport:Energy metabolism:Amino Acid Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Metabolism:Information storage and processing:Other" 290 "Nucleoside-diphosphate-sugar epimerases:UDP-glucose 4-epimerase:Glycosyltransferases, probably involved in cell wall biogenesis:Flagellar motor component:Flagellar biosynthesis pathway, component FliP:Flagellar basal body-associated protein:Flagellar biosynthesis/type III secretory pathway lipoprotein:Uncharacterized conserved protein:Uncharacterized conserved protein:Beta-mannanase:Carbohydrate transport and metabolism:Cell wall/membrane/envelope biogenesis:Cell motility:Galactose metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Polyketide sugar unit biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Bacterial chemotaxis:Flagellar assembly:Function unknown:fliF:fliP:galE:MotA1:Intracellular trafficking, secretion, and vesicular transport:Chemotaxis and motility:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Translation:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Terpenoids and Polyketides:Energy metabolism:Carbohydrate Metabolism:Sugars:Cellular processes" 291 "Energy production and conversion:Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:DNA polymerase III, alpha subunit:Na+/proline symporter:Spermidine/putrescine-binding periplasmic protein:Sec-independent protein secretion pathway component TatC:Uncharacterized ABC-type transport system, permease component:ABC-type spermidine/putrescine transport system, permease component I:ABC-type spermidine/putrescine transport system, permease component II:Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein:Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family:TRAP-type uncharacterized transport system, periplasmic component:ABC-type uncharacterized transport systems, ATPase components:Predicted symporter:Predicted membrane protein:ABC-type uncharacterized transport system, permease component:Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A:Xanthine dehydrogenase, molybdopterin-binding subunit B:TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component:TRAP-type mannitol/chloroaromatic compound transport system, small permease component:Amino acid transport and metabolism:Nucleotide transport and metabolism:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Purine metabolism:Pyrimidine metabolism:Valine leucine and isoleucine biosynthesis:Pyruvate metabolism:Butanoate metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:DNA replication:Protein export:Bacterial secretion system:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:polc:tatC:PDHac_trf_mito:TRAP_TAXI:xanthine_xdhA:xanthine_xdhC:Na_symport_sm:Na_symport_lg:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Carbohydrate Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Pyruvate dehydrogenase:Purines, pyrimidines, nucleosides, and nucleotides:Other:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Unknown substrate:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 292 "Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Hydrogenase maturation factor:Nicotinate-nucleotide pyrophosphorylase:Glycosyltransferase:Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family:Biotin synthase and related enzymes:Metal-dependent proteases with possible chaperone activity:Methyl-accepting chemotaxis protein:Transcriptional regulators of sugar metabolism:Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor):DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog:Cellobiose phosphorylase:Uncharacterized conserved protein:Phage DNA packaging protein, Nu1 subunit of terminase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Posttranslational modification, protein turnover, chaperones:Arginine and proline metabolism:Biotin metabolism:Metabolic pathways:Two-component system:Bacterial chemotaxis:RNA polymerase:Function unknown:Signal transduction mechanisms:hypF:gcp_kae1:ant_ant_sig:bioB:Information storage and processing:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Transcription:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Regulatory functions:Protein interactions:Protein fate:Degradation of proteins, peptides, and glycopeptides:Protein modification and repair:Biosynthesis of cofactors, prosthetic groups, and carriers:Biotin:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 293 "Predicted glutamine amidotransferase:Dihydroorotate dehydrogenase:Trk-type K+ transport systems, membrane components:1-acyl-sn-glycerol-3-phosphate acyltransferase:Ribonucleotide reductase, alpha subunit:Di- and tricarboxylate transporters:ATPases involved in chromosome partitioning:FOG: GGDEF domain:Predicted ornithine cyclodeaminase, mu-crystallin homolog:Uncharacterized protein conserved in bacteria:Arylsulfatase A and related enzymes:Putative hemolysin:Uncharacterized conserved protein:ABC-type spermidine/putrescine transport systems, ATPase components:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Arginine and proline metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:Signal transduction mechanisms:GGDEF:pyrD_sub2:NrdJ_Z:chol_sulfatase:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Other:Signal transduction:2'-Deoxyribonucleotide metabolism" 294 "Phosphoribosyl-ATP pyrophosphohydrolase:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Membrane protease subunits, stomatin/prohibitin homologs:Thiamine monophosphate synthase:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Biopolymer transport protein:ABC-type transport system involved in resistance to organic solvents, ATPase component:Arsenate reductase and related proteins, glutaredoxin family:ABC-type transport system involved in resistance to organic solvents, periplasmic component:Threonine aldolase:Predicted flavoprotein involved in K+ transport:Negative regulator of beta-lactamase expression:Predicted acetyltransferase:Kynureninase:Predicted membrane protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Histidine metabolism:Tryptophan metabolism:Thiamine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:kynureninase:tolR:histidine_hisI:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Histidine family:Amino acid biosynthesis:Pathogenesis:Cellular processes:Amino acids and amines:Energy metabolism:Metabolism:Metabolism:Global:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 295 "Acetyltransferases:TRAP-type C4-dicarboxylate transport system, large permease component:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:TRAP-type C4-dicarboxylate transport system, periplasmic component:Transcriptional regulators:Glucuronate isomerase:Na+/melibiose symporter and related transporters:Predicted NAD/FAD-binding protein:TRAP-type C4-dicarboxylate transport system, small permease component:Uncharacterized conserved protein:Anti-sigma factor:Carbohydrate transport and metabolism:Transcription:Pentose and glucuronate interconversions:Metabolic pathways:RNA polymerase:General function prediction only:Function unknown:Signal transduction mechanisms:dctM:dctP:anti_sig_ChrR:sigma70-ECF:Cellular processes and signaling:Carbohydrate Metabolism:Genetic Information Processing:Transcription:Global:Metabolism:Regulatory functions:Other:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 296 "ADP-glucose pyrophosphorylase:Predicted permease:Uncharacterized conserved protein:Type II secretory pathway, pullulanase PulA and related glycosidases:Arabinose efflux permease:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:General function prediction only:Function unknown:glgX_debranch:Biosynthesis and degradation of polysaccharides:Carbohydrate Metabolism:Genetic Information Processing:Translation:Global:Metabolism:Energy metabolism:Metabolism:Metabolism:Poorly characterized" 297 "Energy production and conversion:Succinyl-CoA synthetase, beta subunit:Succinyl-CoA synthetase, alpha subunit:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Membrane protease subunits, stomatin/prohibitin homologs:Molecular chaperone:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component:Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit:DnaJ-class molecular chaperone with C-terminal Zn finger domain:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes:Isocitrate dehydrogenases:2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Aconitase A:Succinate dehydrogenase/fumarate reductase, flavoprotein subunit:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Acetyltransferases, including N-acetylases of ribosomal proteins:Phosphoenolpyruvate carboxykinase (ATP):Succinate dehydrogenase/fumarate reductase, cytochrome b subunit:Succinate dehydrogenase, hydrophobic anchor subunit:Amino acid transport and metabolism:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Citrate cycle (TCA cycle):Oxidative phosphorylation:Lysine degradation:Tryptophan metabolism:Glutathione metabolism:Pyruvate metabolism:Toluene degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:C5-Branched dibasic acid metabolism:Carbon fixation in photosynthetic organisms:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:RNA degradation:nadp_idh_euk:pckA:2oxo_dh_E1:dhsB:sucCoAbeta:sucCoAalpha:aconitase_1:sucB:sdhA_frdA_Gneg:hflK:degP_htrA_DO:DnaJ_bact:prok_dnaK:succ_dehyd_cytB:Protein fate:TCA cycle:Glycolysis/gluconeogenesis:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Energy Metabolism:Cellular processes and signaling:Carbohydrate Metabolism:Metabolism:Information storage and processing:Degradation of proteins, peptides, and glycopeptides:Protein folding and stabilization" 298 "DNA polymerase III, alpha subunit:Methionine synthase I (cobalamin-dependent), methyltransferase domain:Predicted acyltransferases:Predicted flavoproteins:Permeases of the major facilitator superfamily:DNA-binding HTH domain-containing proteins:Uncharacterized conserved protein:Uncharacterized conserved protein:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cysteine and methionine metabolism:One carbon pool by folate:Metabolic pathways:Biosynthesis of secondary metabolites:General function prediction only:Function unknown:TIGR00275:polc:Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Unknown function:Enzymes of unknown specificity:Information storage and processing:Metabolism:Poorly characterized" 299 "Energy production and conversion:Acetylglutamate semialdehyde dehydrogenase:Putative translation factor (SUA5):3-phosphoglycerate kinase:NAD synthase:Cell division GTPase:Mismatch repair ATPase (MutS family):Dihydrodipicolinate reductase:Homoserine dehydrogenase:S-adenosylhomocysteine hydrolase:Thiol-disulfide isomerase and thioredoxins:Phosphoglyceromutase:ABC-type transport system involved in cytochrome c biogenesis, permease component:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Uncharacterized membrane protein, required for colicin V production:DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes:Uncharacterized protein conserved in bacteria:Cyclopropane fatty acid synthase and related methyltransferases:Holliday junction resolvasome, helicase subunit:ABC-type transport system involved in cytochrome c biogenesis, permease component:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type transport system involved in cytochrome c biogenesis, ATPase component:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Arginine and proline metabolism:Selenocompound metabolism:Glutathione metabolism:Methane metabolism:Carbon fixation in photosynthetic organisms:Nicotinate and nicotinamide metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:dapB:TIGR00052:TIGR00057:ftsZ:dsbE:nadE:ruvB:ahcY:mutS1:ccmA:ccmB:ccmC:pgm_bpd_ind:gluta_reduc_2:argC:cytochro_ccmD:Aspartate family:Carbohydrate Metabolism:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Amino acids and amines:Electron transport:Glycolysis/gluconeogenesis:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein folding and stabilization:Transport and binding proteins:Other:Cellular processes:Cell division:Unknown function:Enzymes of unknown specificity:General:Amino acid biosynthesis:Metabolism:Glutamate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pyridine nucleotides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 300 "Energy production and conversion:Ni,Fe-hydrogenase I large subunit:Uncharacterized flavoproteins:Uncharacterized NAD(FAD)-dependent dehydrogenases:Metal-dependent proteases with possible chaperone activity:Ferredoxin:ABC-type branched-chain amino acid transport systems, periplasmic component:Membrane-associated lipoprotein involved in thiamine biosynthesis:Ni,Fe-hydrogenase I small subunit:Ni,Fe-hydrogenase I cytochrome b subunit:Hydrogenase/urease accessory protein:Protein involved in meta-pathway of phenol degradation:Amino acid transport and metabolism:Coenzyme transport and metabolism:Posttranslational modification, protein turnover, chaperones:Chlorocyclohexane and chlorobenzene degradation:Benzoate degradation:Xylene degradation:Nitrotoluene degradation:Styrene degradation:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:gcp_kae1:hydA:CytB-hydogenase:tape_meas_nterm:urea_ABC_UrtA:Poorly characterized:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Electron transport:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes and signaling:Metabolism:Metabolism" 301 "Glucose-6-phosphate isomerase:Mannitol-1-phosphate/altronate dehydrogenases:Lactoylglutathione lyase and related lyases:6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase:Glucose-6-phosphate 1-dehydrogenase:Pyruvate kinase:Catalase:2-keto-3-deoxy-6-phosphogluconate aldolase:ABC-type metal ion transport system, periplasmic component/surface adhesin:Cation/multidrug efflux pump:Membrane-fusion protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ABC-type Mn2+/Zn2+ transport systems, permease components:ABC-type Mn/Zn transport systems, ATPase component:D-mannonate dehydratase:TRAP-type C4-dicarboxylate transport system, large permease component:TRAP-type C4-dicarboxylate transport system, periplasmic component:Transcriptional regulators:Glucuronate isomerase:TRAP-type C4-dicarboxylate transport system, small permease component:5-keto 4-deoxyuronate isomerase:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Purine metabolism:Arginine and proline metabolism:Tryptophan metabolism:Glutathione metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Methane metabolism:Carbon fixation in photosynthetic organisms:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:uxuA:dctM:dctP:zwf:2A0602:pyruv_kin:eda:pgl:RND_mfp:kduD:Defense mechanisms:Sugars:Biosynthesis and degradation of polysaccharides:Pentose phosphate pathway:Glycolysis/gluconeogenesis:Entner-Doudoroff:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Carbohydrates, organic alcohols, and acids:Unknown substrate:Transport and binding proteins" 302 "Energy production and conversion:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Chromosome segregation ATPases:Membrane transporters of cations and cationic drugs:Permeases of the major facilitator superfamily:Uncharacterized conserved protein:Plastocyanin:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Inorganic ion transport and metabolism:ABC transporters:General function prediction only:Function unknown:SMC_prok_B:pseudoazurin:Energy metabolism:Chromosome-associated proteins:Membrane Transport:Cellular processes and signaling:Metabolism:Poorly characterized:Environmental Information Processing:DNA metabolism:Electron transport" 303 "Energy production and conversion:NAD-dependent aldehyde dehydrogenases:Sugar (pentulose and hexulose) kinases:ABC-type sugar transport system, ATPase component:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Transcriptional regulator:N-acetylglucosamine-6-phosphate deacetylase:ABC-type sugar transport system, periplasmic component:Site-specific recombinases, DNA invertase Pin homologs:Putative NADPH-quinone reductase (modulator of drug activity B):Choline dehydrogenase and related flavoproteins:Transcriptional regulator, contains sigma factor-related N-terminal domain:Predicted membrane protein:Bacteriophage head-tail adaptor:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Glycine serine and threonine metabolism:Amino sugar and nucleotide sugar metabolism:ABC transporters:General function prediction only:Function unknown:nagA:gp16_SPP1:BADH:betA:betaine_BetI:Metabolism:Carbohydrate Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Central intermediary metabolism:Amino sugars:Regulatory functions:DNA interactions:Cellular processes:Adaptations to atypical conditions:Mobile and extrachromosomal element functions:Prophage functions:Information storage and processing:Metabolism:Poorly characterized" 304 "Energy production and conversion:Short-chain dehydrogenases of various substrate specificities:Predicted amidohydrolase:ABC-type branched-chain amino acid transport systems, ATPase component:Predicted dehydrogenases and related proteins:5,10-methylenetetrahydrofolate reductase:Protease subunit of ATP-dependent Clp proteases:Threonine dehydrogenase and related Zn-dependent dehydrogenases:Predicted membrane protein:Heme/copper-type cytochrome/quinol oxidases, subunit 2:Acyl-CoA dehydrogenases:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Anti-sigma regulatory factor (Ser/Thr protein kinase):Phage protein U:Phage terminase, small subunit:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase:Phage terminase-like protein, large subunit:Signal transduction histidine kinase:P2-like prophage tail protein X:S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase:Trimethylamine:corrinoid methyltransferase:Predicted integral membrane protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Oxidative phosphorylation:Purine metabolism:Streptomycin biosynthesis:Inositol phosphate metabolism:Glycerophospholipid metabolism:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:General function prediction only:Function unknown:Signal transduction mechanisms:sensory_box:urea_trans_UrtE:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Amino acids, peptides and amines:Transport and binding proteins:Small molecule interactions:Regulatory functions:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism" 305 "Energy production and conversion:Polyferredoxin:Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Predicted PP-loop superfamily ATPase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:3-deoxy-D-manno-octulosonic-acid transferase:Cytochrome c peroxidase:Cytochrome c, mono- and diheme variants:Cation transport ATPase:Cbb3-type cytochrome oxidase, cytochrome c subunit:Uncharacterized protein, possibly involved in nitrogen fixation:Cbb3-type cytochrome oxidase, subunit 1:Nucleoside 2-deoxyribosyltransferase:ABC-type oligopeptide transport system, periplasmic component:ABC-type uncharacterized transport system, duplicated ATPase component:Cbb3-type cytochrome oxidase, subunit 3:Predicted integral membrane protein linked to a cation pump:Amino acid transport and metabolism:Nucleotide transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Oxidative phosphorylation:Lipopolysaccharide biosynthesis:Propanoate metabolism:Metabolic pathways:ABC transporters:General function prediction only:ccoN:ccoO:ccoP:ccoS:ATPase_P-type:ccoG_rdxA_fixG:Metabolism:Global:Membrane Transport:Environmental Information Processing:Glycan Biosynthesis and Metabolism:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Protein modification and repair:Protein fate:Electron transport:Energy metabolism:Metabolism" 306 "Energy production and conversion:ABC-type phosphate transport system, periplasmic component:N-formylmethionyl-tRNA deformylase:ABC-type phosphate transport system, permease component:ABC-type phosphate transport system, permease component:Phosphatidylserine decarboxylase:Phosphate uptake regulator:Methyl-accepting chemotaxis protein:ABC-type phosphate transport system, ATPase component:Phosphatidylserine synthase:A/G-specific DNA glycosylase:Protein-disulfide isomerase:Predicted acyl-CoA transferases/carnitine dehydratase:Uncharacterized protein conserved in bacteria:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Glycine serine and threonine metabolism:Glycerophospholipid metabolism:Metabolic pathways:ABC transporters:Two-component system:Bacterial chemotaxis:Protein export:Bacterial secretion system:Base excision repair:Function unknown:Signal transduction mechanisms:pept_deformyl:PS_decarb_rel:pssA:3a0107s01c2:3a0107s02c:mutY:phoU_full:phosphate_pstC:Cellular processes and signaling:Lipid Metabolism:Amino Acid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Replication and Repair:Environmental Information Processing:Membrane Transport:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein modification and repair:Transport and binding proteins:Anions:Unknown function:General:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 307 "Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Urease accessory protein UreF:ABC-type sugar transport systems, permease components:Transcriptional regulators of sugar metabolism:ABC-type sugar transport system, periplasmic component:K+-transporting ATPase, A chain:K+-transporting ATPase, c chain:Osmosensitive K+ channel histidine kinase:High-affinity K+ transport system, ATPase chain B:Urease accessory protein UreE:Arabinose efflux permease:Predicted transcriptional regulator:Predicted periplasmic protein:Carbohydrate transport and metabolism:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:ureG:kdpA:kdpC:efflux_Bcr_CflA:ATPase_P-type:potass_kdpF:Transport and binding proteins:Nitrogen metabolism:Central intermediary metabolism:Signal Transduction:Environmental Information Processing:Membrane Transport:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Cations and iron carrying compounds" 308 "Energy production and conversion:Shikimate 5-dehydrogenase:Anaerobic dehydrogenases, typically selenocysteine-containing:Exopolyphosphatase:FAD/FMN-containing dehydrogenases:23S rRNA methylase:Dihydropteroate synthase and related enzymes:Molybdopterin biosynthesis enzyme:Glycosyltransferase:Nucleoside-diphosphate-sugar epimerases:Predicted dehydrogenase:Predicted Zn-dependent peptidases:Nucleoside phosphorylase:Predicted hydrolase (HAD superfamily):Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria):Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):Phosphomannomutase:Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon):Predicted glycosyltransferases:Phosphotransferase system, fructose-specific IIC component:Cell division septal protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Transcriptional regulators:Uncharacterized protein conserved in bacteria:Molybdenum cofactor biosynthesis enzyme:Predicted permeases:Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit:Uncharacterized component of anaerobic dehydrogenases:Predicted homoserine dehydrogenase:Signal transduction histidine kinase:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Purine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Folate biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Phosphotransferase system (PTS):RNA polymerase:Sulfur relay system:General function prediction only:Function unknown:Signal transduction mechanisms:aroE:bisC_fam:rarD:FRU:PTS_HPr_family:glmM:DHPS:HAD-SF-IA-v3:AMP-nucleosdse:torC:G1P_cyt_trans:moaA:sigma70-ECF:1-PFK:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:PTS:Signal transduction:Molybdopterin:Folic acid:Biosynthesis of cofactors, prosthetic groups, and carriers:Aromatic amino acid family:Amino acid biosynthesis:Enzymes of unknown specificity:Unknown function:Unknown substrate:Transport and binding proteins:Amino sugars:Central intermediary metabolism:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Poorly characterized:Carbohydrate Metabolism" 309 "Energy production and conversion:Diaminopimelate decarboxylase:Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog):Dihydroxyacid dehydratase/phosphogluconate dehydratase:Ribosomal protein L27:Uncharacterized conserved protein:Lipoate synthase:Citrate synthase:Glycine cleavage system T protein (aminomethyltransferase):Signal recognition particle GTPase:Integrase:Acetyl-CoA carboxylase beta subunit:Actin-like ATPase involved in cell morphogenesis:Multidrug resistance efflux pump:Integral membrane protein CcmA involved in cell shape determination:Acetyltransferases, including N-acetylases of ribosomal proteins:Inosine-uridine nucleoside N-ribohydrolase:Predicted metal-sulfur cluster biosynthetic enzyme:Surface lipoprotein:ABC-type transport system involved in resistance to organic solvents, auxiliary component:3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase:Opacity protein and related surface antigens:N-acyl-L-homoserine lactone synthetase:ABC-type protease/lipase transport system, ATPase and permease components:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Citrate cycle (TCA cycle):Fatty acid biosynthesis:Purine metabolism:Glycine serine and threonine metabolism:Valine leucine and isoleucine biosynthesis:Arginine and proline metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Glutathione metabolism:Pyruvate metabolism:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:One carbon pool by folate:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Lipoic acid metabolism:Nitrogen metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Ribosome:Protein export:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00049:L27:ftsY:ilvD:gatB:lipA:accD:gcvT:mreB:DAHP_synth_II:cit_synth_I:type_I_sec_PrtD:type_I_hlyD:SUF_assoc:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Folding Sorting and Degradation:Metabolism:Translation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Energy Metabolism:Carbohydrate Metabolism:Energy metabolism:Amino acids and amines:TCA cycle:Fatty acid and phospholipid metabolism:Biosynthesis:Protein synthesis:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:Protein fate:Protein and peptide secretion and trafficking:Amino acid biosynthesis:Aromatic amino acid family:Pyruvate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Lipoate:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Membrane Transport:Environmental Information Processing" 310 "Alanyl-tRNA synthetase:Ribosomal protein S12:GTPases - translation elongation factors:Ribosomal protein S15P/S13E:Ribosomal protein L7/L12:Ribosomal protein L10:Transcription antiterminator:Ribosomal protein L31:Ribosomal protein L29:Ribosomal protein L35:Ribosomal protein L20:Ribosomal protein L19:Ribosomal protein S1:Superoxide dismutase:Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase):Ribosome-associated protein Y (PSrp-1):TRAP-type C4-dicarboxylate transport system, periplasmic component:Preprotein translocase subunit YajC:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Aminoacyl-tRNA biosynthesis:Two-component system:Ribosome:RNA degradation:Protein export:Bacterial secretion system:rpmI_bact:L29:L31:small_GTP:alaS:rpsA:yajC:yfiA:dctP:L12:nusG:S15_bact:rpsL_bact:rplS_bact:rplT_bact:polynuc_phos:Intracellular trafficking, secretion, and vesicular transport:Unknown function:Nucleotide Metabolism:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Transcription:Degradation of RNA:Transcription factors:Protein synthesis:tRNA aminoacylation:Ribosomal proteins: synthesis and modification:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Carbohydrates, organic alcohols, and acids:Metabolism:General:Information storage and processing:Cellular processes and signaling:Metabolism" 311 "Energy production and conversion:tRNA-dihydrouridine synthase:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:Methionyl-tRNA synthetase:Ribonucleotide reductase, alpha subunit:Protein chain release factor A:Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A):Protoheme ferro-lyase (ferrochelatase):Orotidine-5'-phosphate decarboxylase:Aspartate/tyrosine/aromatic aminotransferase:Orotate phosphoribosyltransferase:ATPase components of ABC transporters with duplicated ATPase domains:2-methylthioadenine synthetase:Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit:Selenophosphate synthase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Multisubunit Na+/H+ antiporter, MnhC subunit:NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:Multisubunit Na+/H+ antiporter, MnhG subunit:Protein-disulfide isomerase:Saccharopine dehydrogenase and related proteins:Multisubunit Na+/H+ antiporter, MnhE subunit:Multisubunit Na+/H+ antiporter, MnhF subunit:Cyclopropane fatty acid synthase and related methyltransferases:Uncharacterized protein conserved in bacteria:ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Purine metabolism:Pyrimidine metabolism:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Bisphenol degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Selenocompound metabolism:Chloroalkane and chloroalkene degradation:Butanoate metabolism:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:prfB:efp:TIGR00089:hemH:metG:selD:hisC:CPA3_mnhG_phaG:pyrF:NrdJ_Z:Biosynthesis of cofactors, prosthetic groups, and carriers:Histidine family:Amino acid biosynthesis:Cations and iron carrying compounds:Transport and binding proteins:Translation factors:tRNA aminoacylation:Protein synthesis:2'-Deoxyribonucleotide metabolism:Pyrimidine ribonucleotide biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Signal Transduction:Environmental Information Processing:Translation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Heme, porphyrin, and cobalamin" 312 "Ribosomal protein S12:Ribosomal protein S7:Ribosomal protein S10:Ribosomal protein L3:Ribosomal protein L4:Ribosomal protein L23:Ribosomal protein L2:Ribosomal protein L22:Ribosomal protein S3:Ribosomal protein S19:Co-chaperonin GroES (HSP10):Ribosomal protein S18:Ribosomal protein L29:Ribosomal protein L21:Chaperonin GroEL (HSP60 family):Translation elongation factors (GTPases):Ribosomal protein S4 and related proteins:Translation, ribosomal structure and biogenesis:Posttranslational modification, protein turnover, chaperones:Ribosome:RNA degradation:L29:L21:S18:small_GTP:rpsL_bact:rpsC_bact:rpsD_bact:rpsG_bact:rplV_bact:rpsJ_bact:rpsS_bact:rplB_bact:GroEL:L3_bact:rplD_bact:Folding Sorting and Degradation:Cellular processes and signaling:Translation:Information storage and processing:General:Unknown function:Protein folding and stabilization:Protein fate:Ribosomal proteins: synthesis and modification:Protein synthesis:Genetic Information Processing" 313 "Energy production and conversion:Predicted flavoprotein:Catalase:Predicted transcriptional regulators:Arabinose efflux permease:Cytochrome c553:Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF:Predicted phosphatase:Phage terminase, small subunit:ABC-type branched-chain amino acid transport system, permease component:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Predicted membrane protein:Uncharacterized protein conserved in bacteria:Phage terminase-like protein, large subunit:Uncharacterized ABC-type transport system, ATPase component:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Tryptophan metabolism:Methane metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:resist_ArsH:fdxN_nitrog:urea_trans_UrtC:urea_trans_UrtD:Cellular processes and signaling:Energy Metabolism:Amino Acid Metabolism:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Nitrogen fixation:Transport and binding proteins:Amino acids, peptides and amines:Cellular processes:Detoxification:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 314 "Flagellar hook-associated protein:Flagellar biosynthesis pathway, component FlhA:Flagellin and related hook-associated proteins:Flagellar basal body rod protein:Flagellar basal-body P-ring protein:Flagellar hook protein FlgE:Flagellar basal body protein:Flagellar hook capping protein:Flagellar basal body L-ring protein:Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains:Flagellar basal body rod protein:Transcription:Cell motility:Flagellar assembly:Signal transduction mechanisms:FlgC:FlgB:FlhA:flgG_G_neg:flgK_ends:flagell_flgL:FlgEFG_subfam:Intracellular trafficking, secretion, and vesicular transport:Cell Motility:Cellular processes and signaling:Cellular Processes:Chemotaxis and motility:Cellular processes:Information storage and processing" 315 "" 316 "Methionyl-tRNA synthetase:dGTP triphosphohydrolase:Methylated DNA-protein cysteine methyltransferase:Superfamily II DNA and RNA helicases:Pseudouridylate synthases, 23S RNA-specific:Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases:Cation/multidrug efflux pump:Membrane-fusion protein:ABC-type multidrug transport system, ATPase and permease components:Predicted glycosyltransferases:Transcriptional regulator:Truncated, possibly inactive, lysyl-tRNA synthetase (class II):2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase:Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Purine metabolism:Lysine biosynthesis:Tyrosine metabolism:Selenocompound metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Microbial metabolism in diverse environments:RNA degradation:General function prediction only:rluA_subfam:metG:genX:ogt:2A0602:dapE_proteo:dGTP_triPase:RND_mfp:MsbA_rel:Defense mechanisms:Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Translation:Folding Sorting and Degradation:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Transport and binding proteins:Unknown substrate:Unknown function:General:Amino acid biosynthesis:Aspartate family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 317 "Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase:Translation initiation factor 3 (IF-3):Thiamine monophosphate synthase:Predicted aminomethyltransferase related to GcvT:Transcriptional regulators:ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain:Uncharacterized protein involved in cation transport:Amino acid transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Inorganic ion transport and metabolism:Alanine aspartate and glutamate metabolism:Glycine serine and threonine metabolism:Methane metabolism:Thiamine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:infC:ygfZ_signature:Defense mechanisms:Information storage and processing:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Protein synthesis:tRNA and rRNA base modification:Translation factors:Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized" 318 "Energy production and conversion:tRNA-dihydrouridine synthase:Malic enzyme:Sugar kinases, ribokinase family:Hypoxanthine-guanine phosphoribosyltransferase:Predicted permeases:Phosphatidylglycerophosphatase A and related proteins:Uncharacterized protein (competence- and mitomycin-induced):NaMN:DMB phosphoribosyltransferase:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Oligoketide cyclase/lipid transport protein:Signal transduction histidine kinase, nitrogen specific:Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Pentose phosphate pathway:Purine metabolism:Glycerophospholipid metabolism:Pyruvate metabolism:Carbon fixation in photosynthetic organisms:Riboflavin metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:General function prediction only:Signal transduction mechanisms:cinA_cterm:nifR3_yhdG:HGPRTase:cobT_DBIPRT:Cellular processes and signaling:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Salvage of nucleosides and nucleotides:DNA metabolism:DNA replication, recombination, and repair:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Heme, porphyrin, and cobalamin:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 319 "" 320 "1,4-alpha-glucan branching enzyme:Glycosidases:Transcriptional regulator:Fucose permease:FOG: CheY-like receiver:Methyl-accepting chemotaxis protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Type II secretory pathway, pullulanase PulA and related glycosidases:4-alpha-glucanotransferase:Flagellar hook capping protein:Maltooligosyl trehalose synthase:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell motility:Starch and sucrose metabolism:Metabolic pathways:Two-component system:Bacterial chemotaxis:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:malQ:branching_enzym:glgX_debranch:phage_TIGR02216:trehalose_TreY:trehalose_TreZ:treS_nterm:Metabolism:Cellular processes and signaling:Information storage and processing:Prophage functions:Mobile and extrachromosomal element functions:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Poorly characterized:Carbohydrate Metabolism" 321 "Energy production and conversion:GTPases - translation elongation factors:Ribosomal protein S17:4-hydroxybenzoate polyprenyltransferase and related prenyltransferases:Acetyltransferases:Dehydrogenases (flavoproteins):Fe-S oxidoreductase:Isopentenyldiphosphate isomerase:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Ribosome:General function prediction only:small_GTP:chlor_syn_BchG:BchJ:BchP-ChlP:BchE:IPP_isom_1:S17_bact:Chlorophyll and bacteriochlorphyll:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Translation:Global:Metabolism:Protein synthesis:Ribosomal proteins: synthesis and modification:Unknown function:General:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Metabolism:Information storage and processing:Metabolism:Poorly characterized" 322 "Energy production and conversion:FAD/FMN-containing dehydrogenases:Pseudouridylate synthases, 23S RNA-specific:Signal transduction histidine kinase:FOG: GGDEF domain:Uncharacterized protein related to deoxyribodipyrimidine photolyase:Translation, ribosomal structure and biogenesis:General function prediction only:Signal transduction mechanisms:rluA_subfam:GGDEF:Metabolism:Cellular processes and signaling:Information storage and processing:Poorly characterized:Signal transduction:tRNA and rRNA base modification:Protein synthesis:Other" 323 "Acetylglutamate semialdehyde dehydrogenase:Diaminopimelate decarboxylase:5-enolpyruvylshikimate-3-phosphate synthase:Peptidyl-tRNA hydrolase:Asparagine synthase (glutamine-hydrolyzing):Transcriptional regulator:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Predicted transcriptional regulators:Esterase/lipase:Permeases of the drug/metabolite transporter (DMT) superfamily:Uncharacterized conserved protein:Transcriptional regulator:Uncharacterized conserved protein:Pyrimidine reductase, riboflavin biosynthesis:Uncharacterized protein, possibly involved in aromatic compounds catabolism:Uncharacterized conserved protein:ABC-type sugar transport systems, ATPase components:L-asparaginase II:Site-specific recombinase XerD:Predicted transmembrane transcriptional regulator (anti-sigma factor):Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Alanine aspartate and glutamate metabolism:Lysine biosynthesis:Arginine and proline metabolism:Bisphenol degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Aminobenzoate degradation:Riboflavin metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:ribD_Cterm:unchar_dom_1:pth:TIGR00697:nspC:pro_imino_pep_1:aroA:argC:two_anch:Aromatic amino acid family:Energy Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Global:Metabolism:Central intermediary metabolism:Polyamine biosynthesis:Protein synthesis:Other:Hypothetical proteins:Conserved:Domain:Amino acid biosynthesis:Metabolism:Glutamate family:Information storage and processing:Metabolism:Poorly characterized" 324 "" 325 "Energy production and conversion:ABC-type sugar transport system, permease component:Glycosyltransferase:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:NADPH:quinone reductase and related Zn-dependent oxidoreductases:Signal transduction histidine kinase:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:ABC-type branched-chain amino acid transport systems, periplasmic component:ABC-type dipeptide transport system, periplasmic component:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):ATPase components of various ABC-type transport systems, contain duplicated ATPase:Sortase and related acyltransferases:Putative threonine efflux protein:Predicted phosphatase:Predicted membrane protein:Protein containing von Willebrand factor type A (vWA) domain:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Phage terminase-like protein, large subunit:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Glyoxylate and dicarboxylate metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:crot-CoA-red:Metabolism:Global:Poorly characterized:Membrane Transport:Environmental Information Processing:Metabolism:Lipid Metabolism:Carbohydrate Metabolism:Cellular processes and signaling:Metabolism" 326 "Energy production and conversion:Xaa-Pro aminopeptidase:Predicted ATPase of the PP-loop superfamily implicated in cell cycle control:Ribonucleotide reductase, alpha subunit:Predicted membrane protein:Glycosyltransferase:Pseudouridylate synthases, 23S RNA-specific:Cell division protein FtsI/penicillin-binding protein 2:Periplasmic component of the Tol biopolymer transport system:Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs:Uncharacterized protein conserved in bacteria:Dihydroneopterin aldolase:Uncharacterized Fe-S protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Uncharacterized protein conserved in bacteria:Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain:Uncharacterized conserved protein:Small-conductance mechanosensitive channel:ABC-type uncharacterized transport system, duplicated ATPase component:Site-specific recombinase XerD:Chaperone required for the assembly of the mitochondrial F1-ATPase:Uncharacterized conserved protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Peptidoglycan biosynthesis:Glycerolipid metabolism:Glycerophospholipid metabolism:Folate biosynthesis:Metabolic pathways:ABC transporters:General function prediction only:Function unknown:rluA_subfam:TIGR00023:folB_dom:lysidine_TilS_N:NrdJ_Z:tol_pal_ybgF:propeller_TolB:Intracellular trafficking, secretion, and vesicular transport:Fatty acid and phospholipid metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Nucleotide Metabolism:Poorly characterized:Lipid Metabolism:Metabolism:Cellular processes and signaling:Information storage and processing:Pathogenesis:Cellular processes:tRNA and rRNA base modification:Protein synthesis:2'-Deoxyribonucleotide metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis" 327 "Energy production and conversion:Ribosomal protein L28:Acyl carrier protein:Ribosomal protein L33:Ribosomal protein S20:Ribonuclease HI:Translation initiation factor 1 (IF-1):Bacterial nucleoid DNA-binding protein:Ferredoxin:Cold shock proteins:DNA-directed RNA polymerase, subunit K/omega:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized conserved small protein:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Purine metabolism:Pyrimidine metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Ribosome:RNA polymerase:DNA replication:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:infA:L28:S20:acyl_carrier:rpoZ:rpmJ_bact:rpmG_bact:rpmH_bact:thioredoxin:yccV:Poorly characterized:Nucleotide Metabolism:Genetic Information Processing:Transcription:Translation:Replication and Repair:Global:Metabolism:Energy metabolism:Electron transport:Fatty acid and phospholipid metabolism:Biosynthesis:Transcription:DNA-dependent RNA polymerase:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Information storage and processing:Metabolism:Metabolism" 328 "" 329 "Zn-dependent oligopeptidases:ATPases involved in chromosome partitioning:Transcriptional regulator:5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases:Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains):Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Adenine deaminase:Tellurite resistance protein and related permeases:Predicted metal-dependent hydrolase with the TIM-barrel fold:Membrane protein involved in the export of O-antigen and teichoic acid:Lysophospholipase:ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain:Transthyretin-like protein:Putative glycerate kinase:Uncharacterized protein involved in outer membrane biogenesis:Bacterial lipocalin:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Signal transduction histidine kinase:Predicted membrane protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Glyoxylate and dicarboxylate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:ade:hdxy_isourate:Defense mechanisms:Cellular processes and signaling:Information storage and processing:Salvage of nucleosides and nucleotides:Other:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Global:Signal Transduction:Environmental Information Processing:Amino Acid Metabolism:Nucleotide Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Metabolism" 330 "Energy production and conversion:Transcriptional regulator:Nitrogenase subunit NifH (ATPase):Cobalamin biosynthesis protein CobN and related Mg-chelatases:2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase:Nitrogenase molybdenum-iron protein, alpha and beta chains:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:DPOR_BchB:DPOR_bchL:BchM-ChlM:AcsF:photo_alph_chp1:photo_alph_chp2:Photosynthesis:Metabolism of Cofactors and Vitamins:Global:Metabolism:Energy metabolism:Metabolism:Biosynthesis of cofactors, prosthetic groups, and carriers:Chlorophyll and bacteriochlorphyll:Information storage and processing:Metabolism" 331 "Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:Formamidopyrimidine-DNA glycosylase:Predicted esterase:ABC-type Fe3+-hydroxamate transport system, periplasmic component:Spermidine/putrescine-binding periplasmic protein:Predicted permeases:Fe2+/Zn2+ uptake regulation proteins:ABC-type Mn2+/Zn2+ transport systems, permease components:ABC-type Mn/Zn transport systems, ATPase component:ABC-type spermidine/putrescine transport system, permease component I:Predicted transcriptional regulators:Disulfide bond formation protein DsbB:Transcriptional regulators:Sugar phosphate permease:Uncharacterized protein conserved in bacteria:Predicted periplasmic or secreted protein:Proline racemase:ABC-type Zn2+ transport system, periplasmic component/surface adhesin:Predicted phage phi-C31 gp36 major capsid-like protein:Phage-related protein:Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Arginine and proline metabolism:Metabolic pathways:ABC transporters:Base excision repair:General function prediction only:Function unknown:fpg:portal_HK97:major_cap_HK97:degP_htrA_DO:Information storage and processing:Prophage functions:Mobile and extrachromosomal element functions:Degradation of proteins, peptides, and glycopeptides:Protein fate:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism:Amino Acid Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling" 332 "Energy production and conversion:Isopropylmalate/homocitrate/citramalate synthases:Uncharacterized conserved protein:Predicted Fe-S oxidoreductases:NifU homolog involved in Fe-S cluster formation:Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes:Nitrogenase subunit NifH (ATPase):Nitrogenase molybdenum-iron protein, alpha and beta chains:Predicted NADH:ubiquinone oxidoreductase, subunit RnfB:Uncharacterized protein conserved in bacteria:Predicted NADH:ubiquinone oxidoreductase, subunit RnfC:Predicted NADH:ubiquinone oxidoreductase, subunit RnfA:Predicted NADH:ubiquinone oxidoreductase, subunit RnfD:Predicted NADH:ubiquinone oxidoreductase, subunit RnfG:Predicted NADH:ubiquinone oxidoreductase, subunit RnfE:Amino acid transport and metabolism:Inorganic ion transport and metabolism:Lysine biosynthesis:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Thiamine metabolism:Nitrogen metabolism:Metabolic pathways:Microbial metabolism in diverse environments:Sulfur relay system:General function prediction only:Function unknown:TIGR00049:nifD:nifE:nifN:nifK:nifH:nifB:rnfA:rnfB:rnfC:rnfD:rnfG:rnfE:nifX:TIGR02935:FeS_nifS:Biosynthesis of cofactors, prosthetic groups, and carriers:Electron transport:Energy metabolism:Nitrogen fixation:Central intermediary metabolism:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Genetic Information Processing:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Poorly characterized:Other" 333 "" 334 "" 335 "Glycosyltransferase:Topoisomerase IA:A/G-specific DNA glycosylase:HrpA-like helicases:Predicted acyltransferases:Signal transduction histidine kinase:Uncharacterized conserved protein:Lipid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Base excision repair:Function unknown:Signal transduction mechanisms:topA_bact:mutY:DEAH_box_HrpB:Poorly characterized:Replication and Repair:DNA metabolism:DNA replication, recombination, and repair:Unknown function:Enzymes of unknown specificity:Information storage and processing:Cellular processes and signaling:Metabolism:Genetic Information Processing" 336 "Aminoacyl-tRNA biosynthesis:Genetic Information Processing:Translation" 337 "Energy production and conversion:Hydrogenase maturation factor:Phosphoglycerate dehydrogenase and related dehydrogenases:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Mannitol-1-phosphate/altronate dehydrogenases:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Methylated DNA-protein cysteine methyltransferase:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type branched-chain amino acid transport systems, periplasmic component:Demethylmenaquinone methyltransferase:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Predicted permeases:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Alcohol dehydrogenase, class IV:Transcriptional regulators:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:Glucose/sorbosone dehydrogenases:Predicted acetyltransferase:Uncharacterized protein conserved in bacteria:Transcriptional activator of acetoin/glycerol metabolism:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Glycine serine and threonine metabolism:Valine leucine and isoleucine degradation:Lysine biosynthesis:Benzoate degradation:C5-Branched dibasic acid metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:hypF:ogt:Carbohydrate Metabolism:Protein modification and repair:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:DNA replication, recombination, and repair:DNA metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Amino Acid Metabolism:Energy Metabolism:Protein fate" 338 "Energy production and conversion:Molybdopterin biosynthesis enzyme:Zn-dependent hydrolases, including glyoxylases:Predicted Fe-S oxidoreductases:Transcriptional regulator:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component:Metal-dependent hydrolases of the beta-lactamase superfamily I:Na+/phosphate symporter:Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs:Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs:Predicted flavoprotein involved in K+ transport:Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs:Transcriptional activator of acetoin/glycerol metabolism:Uncharacterized conserved protein:Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C:Predicted secreted protein:Coenzyme transport and metabolism:Transcription:Inorganic ion transport and metabolism:Nitrotoluene degradation:Methane metabolism:Microbial metabolism in diverse environments:ABC transporters:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:PQQ_syn_pqqB:PQQ_syn_pqqE:PQQ_syn_pqqC:PQQ_PqqD:Energy Metabolism:Metabolism:Metabolism:Information storage and processing:Other:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Global:Membrane Transport:Environmental Information Processing:Xenobiotics Biodegradation and Metabolism:Poorly characterized" 339 "ATPase involved in DNA repair:SAM-dependent methyltransferases:Superfamily II DNA helicase:Prolipoprotein diacylglyceryltransferase:Periplasmic component of the Tol biopolymer transport system:UDP-glucose 4-epimerase:Uncharacterized conserved protein:Uncharacterized conserved protein:Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain:Membrane glycosyltransferase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Periplasmic glucans biosynthesis protein:Small-conductance mechanosensitive channel:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Glycerophospholipid metabolism:Metabolic pathways:RNA degradation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:lgt:recQ_fam:recN:TIGR00726:propeller_TolB:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Carbohydrate Metabolism:Lipid Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein fate:Protein modification and repair:Cellular processes:Pathogenesis:Unknown function:General:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 340 "Chromatin structure and dynamics:Energy production and conversion:Deacetylases, including yeast histone deacetylase and acetoin utilization protein:Thymidylate kinase:Nuclease subunit of the excinuclease complex:Glycosidases:Transcriptional regulator:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Permeases of the drug/metabolite transporter (DMT) superfamily:Cation/multidrug efflux pump:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:Transcription-repair coupling factor (superfamily II helicase):Primosomal protein N' (replication factor Y) - superfamily II helicase:Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes:Type II secretory pathway, pullulanase PulA and related glycosidases:Flagellar biosynthesis pathway, component FliR:Predicted CoA-binding protein:FOG: PAS/PAC domain:AraC-type DNA-binding domain-containing proteins:Uncharacterized protein with SCP/PR1 domains:16S RNA G1207 methylase RsmC:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Site-specific recombinase XerD:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell motility:Inorganic ion transport and metabolism:Pyrimidine metabolism:Metabolic pathways:ABC transporters:Flagellar assembly:Nucleotide excision repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:DTMP_kinase:uvrC:sensory_box:mfd:priA:glgX_debranch:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Genetic Information Processing:Cellular processes and signaling:Nucleotide Metabolism:Metabolism:Poorly characterized:Information storage and processing:DNA replication, recombination, and repair:Metabolism:DNA metabolism:Small molecule interactions:Regulatory functions:Nucleotide and nucleoside interconversions:Purines, pyrimidines, nucleosides, and nucleotides:Biosynthesis and degradation of polysaccharides:Energy metabolism:Metabolism:Global:Cell Motility:Cellular Processes:Membrane Transport:Environmental Information Processing:Replication and Repair" 341 "Phosphoenolpyruvate synthase/pyruvate phosphate dikinase:Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family):Signal transduction histidine kinase:Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain:Predicted ATPase or kinase:ABC-type cobalt transport system, ATPase component:Cold shock proteins:Uncharacterized conserved protein:Recombinational DNA repair protein (RecF pathway):Transcriptional regulator:Uracil-DNA glycosylase:Predicted P-loop-containing kinase:Phosphotransferase system, HPr-related proteins:SufE protein probably involved in Fe-S center assembly:Transcriptional regulators:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Phosphotransferase system, mannose/fructose-specific component IIA:Putative hemolysin:Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain:Uncharacterized protein conserved in bacteria:Carbohydrate transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Fructose and mannose metabolism:Amino sugar and nucleotide sugar metabolism:Pyruvate metabolism:Carbon fixation in photosynthetic organisms:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Phosphotransferase system (PTS):Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:HI0065_YjeE:reco:UDG_fam4:PTS_HPr_family:PHA_reg_PhaR:Phn_opern_protn:Metabolism:Cellular processes and signaling:Information storage and processing:PTS:Signal transduction:Enzymes of unknown specificity:Unknown function:DNA replication, recombination, and repair:DNA metabolism:DNA interactions:Regulatory functions:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Energy Metabolism:Poorly characterized:Carbohydrate Metabolism" 342 "Site-specific DNA methylase:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:Glutathione S-transferase:ABC-type spermidine/putrescine transport system, permease component II:Flagellar biosynthesis pathway, component FlhA:DNA polymerase III, delta subunit:TRAP-type C4-dicarboxylate transport system, large permease component:TRAP-type C4-dicarboxylate transport system, periplasmic component:Flagellar hook capping protein:Pyridoxal phosphate biosynthesis protein:ABC-type proline/glycine betaine transport systems, periplasmic components:Transcriptional regulators:TRAP-type C4-dicarboxylate transport system, small permease component:Uncharacterized protein conserved in bacteria:ABC-type proline/glycine betaine transport system, ATPase component:ABC-type proline/glycine betaine transport system, permease component:Bacteriophage tail assembly protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell motility:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Glutathione metabolism:Vitamin B6 metabolism:Metabolic pathways:ABC transporters:Flagellar assembly:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:pdxA:dctM:dctP:proV:FlhA:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Pyridoxine:Biosynthesis of cofactors, prosthetic groups, and carriers:Chemotaxis and motility:Cellular processes:Carbohydrates, organic alcohols, and acids:Amino acids, peptides and amines:Transport and binding proteins:Metabolism:Global:Cell Motility:Cellular Processes:Membrane Transport:Environmental Information Processing:Replication and Repair:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Metabolism of Other Amino Acids:Nucleotide Metabolism" 343 "FAD synthase:Pyridoxamine-phosphate oxidase:Aspartate/tyrosine/aromatic aminotransferase:Putative threonine efflux protein:Septum formation initiator:Signal transduction histidine kinase, nitrogen specific:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Riboflavin metabolism:Vitamin B6 metabolism:Metabolic pathways:Two-component system:Signal transduction mechanisms:ribF:sensory_box:pdxH:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism of Cofactors and Vitamins:Environmental Information Processing:Signal Transduction:Global:Metabolism:Regulatory functions:Small molecule interactions:Metabolism:Pyridoxine:Riboflavin, FMN, and FAD:Cellular processes and signaling:Metabolism" 344 "Energy production and conversion:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):NAD-dependent aldehyde dehydrogenases:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Lactate dehydrogenase and related dehydrogenases:Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB):Glycosyltransferases, probably involved in cell wall biogenesis:Predicted phosphohydrolases:Predicted acetamidase/formamidase:Septum formation initiator:Endoglucanase Y:Cell cycle control, cell division, chromosome partitioning:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Galactose metabolism:Ascorbate and aldarate metabolism:Fatty acid metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tyrosine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Starch and sucrose metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Methane metabolism:Limonene and pinene degradation:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:SSADH:VCBS_repeat:CelA:1-PFK:Carbohydrate Metabolism:Central intermediary metabolism:Other:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Global:Metabolism:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism" 345 "Nucleoside diphosphate kinase:Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A):Acyl carrier protein:Putative translation initiation inhibitor, yjgF family:Translation initiation factor 3 (IF-3):Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family:MoxR-like ATPases:Protease subunit of ATP-dependent Clp proteases:Bacterial nucleoid DNA-binding protein:Uncharacterized homolog of plant Iojap protein:Uncharacterized conserved protein:DnaK suppressor protein:Nucleotide transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:efp:iojap_ybeB:infC:acyl_carrier:thioredoxin:dksA:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Information storage and processing:General:Unknown function:Translation factors:Protein synthesis:Small molecule interactions:Regulatory functions:Biosynthesis:Fatty acid and phospholipid metabolism:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Poorly characterized:Nucleotide Metabolism:Metabolism" 346 "Xaa-Pro aminopeptidase:ABC-type amino acid transport system, permease component:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:ABC-type polar amino acid transport system, ATPase component:Predicted DNA-binding protein with the Helix-hairpin-helix motif:L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily:Amino acid transport and metabolism:Cell wall/membrane/envelope biogenesis:Glycine serine and threonine metabolism:Arginine and proline metabolism:Metabolic pathways:General function prediction only:Signal transduction mechanisms:HEQRo_perm_3TM:rSAM_link_UDG:Cellular processes and signaling:Amino Acid Metabolism:Global:Metabolism:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:Enzymes of unknown specificity:Metabolism:Metabolism:Poorly characterized" 347 "Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase:Thiamine monophosphate synthase:ABC-type nitrate/sulfonate/bicarbonate transport system, permease component:ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components:Long-chain acyl-CoA synthetases (AMP-forming):ABC-type sulfate/molybdate transport systems, ATPase component:Hydroxyethylthiazole kinase, sugar kinase family:Coenzyme transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Fatty acid metabolism:Thiamine metabolism:Metabolic pathways:ABC transporters:HMP-P_kinase:thiE:thiM:Metabolism:Thiamine:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Metabolism of Cofactors and Vitamins:Lipid Metabolism" 348 "" 349 "Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:Transaldolase:(acyl-carrier-protein) S-malonyltransferase:Aspartate/tyrosine/aromatic aminotransferase:Nucleoside-diphosphate-sugar epimerases:Leucyl-tRNA synthetase:Na+-driven multidrug efflux pump:Phosphatidylglycerophosphate synthase:UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase:UDP-N-acetylglucosamine enolpyruvyl transferase:Bacterial cell division membrane protein:Actin-like ATPase involved in cell division:D-alanine-D-alanine ligase and related ATP-grasp enzymes:Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains:Cell division septal protein:Periplasmic protein involved in polysaccharide export:DNA segregation ATPase FtsK/SpoIIIE and related proteins:Uncharacterized bacitracin resistance protein:Sugar transferases involved in lipopolysaccharide synthesis:3-methyladenine DNA glycosylase:Membrane-bound lytic murein transglycosylase B:Uncharacterized protein conserved in bacteria:DNA uptake lipoprotein:Predicted secreted (periplasmic) protein:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Pentose phosphate pathway:Fatty acid biosynthesis:Oxidative phosphorylation:Valine leucine and isoleucine biosynthesis:D-Alanine metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Glycerophospholipid metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Base excision repair:General function prediction only:Function unknown:fabD:gatA:TIGR00244:leuS_bact:pgsA:tag:undec_PP_bacA:matE:fsa_talC_mipB:murA:ftsA:D_ala_D_alaTIGR:ftsW:OM_YfiO:Defense mechanisms:Biosynthesis:Fatty acid and phospholipid metabolism:Pentose phosphate pathway:Energy metabolism:Metabolism:Metabolism:Global:Replication and Repair:Translation:Genetic Information Processing:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:DNA interactions:Carbohydrate Metabolism:DNA metabolism:DNA replication, recombination, and repair:Protein synthesis:tRNA aminoacylation:Protein fate:Protein and peptide secretion and trafficking:Transport and binding proteins:Other:Cellular processes:Cell division:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:Regulatory functions" 350 "Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Fructose-2,6-bisphosphatase:Uncharacterized protein conserved in bacteria:Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase:Uncharacterized iron-regulated protein:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Porphyrin and chlorophyll metabolism:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:Poorly characterized:Metabolism of Cofactors and Vitamins:Metabolism:Metabolism:Metabolism:Global" 351 "" 352 "Sugar kinases, ribokinase family:Chemotaxis protein histidine kinase and related kinases:FOG: CheY-like receiver:Methyl-accepting chemotaxis protein:Flagellin and related hook-associated proteins:Carbohydrate transport and metabolism:Cell motility:Two-component system:Bacterial chemotaxis:Flagellar assembly:Signal transduction mechanisms:put_DNA_pack:FlgM_jcvi:Prophage functions:Signal Transduction:Cellular Processes:Cell Motility:Mobile and extrachromosomal element functions:Environmental Information Processing:Cellular processes and signaling:Metabolism" 353 "Energy production and conversion:Deoxyribose-phosphate aldolase:Sugar kinases, ribokinase family:Heme/copper-type cytochrome/quinol oxidases, subunit 1:ABC-type sugar transport system, ATPase component:Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components:Transcriptional regulators of sugar metabolism:Methylase of chemotaxis methyl-accepting proteins:ABC-type sugar transport system, periplasmic component:Delta 1-pyrroline-5-carboxylate dehydrogenase:Integral membrane protein:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell motility:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid metabolism:Oxidative phosphorylation:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Function unknown:Signal transduction mechanisms:deoC:sensory_box:D_ribokin_bact:CtaD_CoxA:Electron transport:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Terpenoids and Polyketides:Xenobiotics Biodegradation and Metabolism:Environmental Information Processing:Signal Transduction:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:Metabolism:Other:Sugars:Regulatory functions:Small molecule interactions:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 354 "Energy production and conversion:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:Glycerol-3-phosphate dehydrogenase:Acyl carrier protein phosphodiesterase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Coenzyme transport and metabolism:Lipid transport and metabolism:Glycerophospholipid metabolism:Nitrogen metabolism:Function unknown:Poorly characterized:Energy Metabolism:Metabolism:Metabolism:Lipid Metabolism" 355 "Energy production and conversion:Acyl carrier protein:Site-specific DNA methylase:Isocitrate/isopropylmalate dehydrogenase:tRNA nucleotidyltransferase/poly(A) polymerase:Flagellar motor protein:Micrococcal nuclease (thermonuclease) homologs:Predicted membrane protein involved in D-alanine export:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Predicted enzyme involved in methoxymalonyl-ACP biosynthesis:Predicted membrane protein:Phage-related protein:Amino acid transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Cell motility:Glyoxylate and dicarboxylate metabolism:Butanoate metabolism:RNA degradation:Mismatch repair:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:portal_HK97:HAD-SF-IIIC:TTC:Information storage and processing:Carbohydrate Metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Prophage functions:Mobile and extrachromosomal element functions:Other:Energy metabolism:Replication and Repair:Folding Sorting and Degradation:Genetic Information Processing" 356 "Ketol-acid reductoisomerase:Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase:N-methylhydantoinase A/acetone carboxylase, beta subunit:Phosphoribosylamine-glycine ligase:Predicted S-adenosylmethionine-dependent methyltransferase:tRNA-(guanine-N1)-methyltransferase:Molecular chaperone:Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain:NADPH-dependent glutamate synthase beta chain and related oxidoreductases:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Demethylmenaquinone methyltransferase:Predicted permeases:Lysine 2,3-aminomutase:Transcriptional regulators:Uncharacterized conserved protein:Cell shape-determining protein:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases:FOG: GGDEF domain:Arabinose efflux permease:Uncharacterized conserved protein:Acetyl/propionyl-CoA carboxylase, alpha subunit:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Lysine degradation:Histidine metabolism:Tyrosine metabolism:Phenylalanine metabolism:Benzoate degradation:Phenylalanine tyrosine and tryptophan biosynthesis:Novobiocin biosynthesis:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:C5-Branched dibasic acid metabolism:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Sulfur relay system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:trmD:mreC:TIGR00238:GGDEF:trmU:mazG:ilvC:purD:hisC:gltD_gamma_fam:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Biosynthesis of Other Secondary Metabolites:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Folding Sorting and Degradation:Global:Metabolism:Energy metabolism:Electron transport:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Protein synthesis:tRNA and rRNA base modification:Unknown function:General:Amino acid biosynthesis:Pyruvate family:Histidine family:Signal transduction:Other:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 357 "ATPases involved in chromosome partitioning:Uncharacterized conserved protein:Predicted Rossmann fold nucleotide-binding protein:Pterin-4a-carbinolamine dehydratase:Lysophospholipase:Zn-dependent dipeptidase, microsomal dipeptidase homolog:Putative Mg2+ and Co2+ transporter CorB:Response regulator:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Inorganic ion transport and metabolism:Glycerophospholipid metabolism:Two-component system:General function prediction only:Function unknown:Signal transduction mechanisms:TIGR00730:Lipid Metabolism:Poorly characterized:Cellular processes and signaling:Metabolism:Conserved:Hypothetical proteins:Signal Transduction:Environmental Information Processing:Metabolism" 358 "3-polyprenyl-4-hydroxybenzoate decarboxylase:Nitrogen regulatory protein PII:Recombinational DNA repair protein (RecF pathway):Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2:Lhr-like helicases:Transglutaminase-like enzymes, putative cysteine proteases:D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4):Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Transcriptional regulator, contains sigma factor-related N-terminal domain:Predicted ATP-dependent endonuclease of the OLD family:ABC-type spermidine/putrescine transport systems, ATPase components:ABC-type uncharacterized transport systems, ATPase components:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Ubiquinone and other terpenoid-quinone biosynthesis:Oxidative phosphorylation:Peptidoglycan biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Two-component system:Nucleotide excision repair:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:ubiX_pad:recR:PBP4:potA:PpsR-CrtJ:Poorly characterized:Energy Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Replication and Repair:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Photosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transport and binding proteins:Amino acids, peptides and amines:Unknown function:Enzymes of unknown specificity:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 359 "N-methylhydantoinase A/acetone carboxylase, beta subunit:N-methylhydantoinase B/acetone carboxylase, alpha subunit:Glycine/D-amino acid oxidases (deaminating):Permeases of the drug/metabolite transporter (DMT) superfamily:Flagellar biosynthesis/type III secretory pathway ATPase:Predicted transcriptional regulators:Flagellar basal body rod protein:Flagellar hook-basal body protein:Flagellar basal body protein:Flagellar biosynthesis pathway, component FliQ:Flagellar basal body L-ring protein:Predicted enzyme of the cupin superfamily:Flagellar basal body rod protein:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Transcription:Cell motility:Glycine serine and threonine metabolism:Arginine and proline metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Flagellar assembly:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:fliI_yscN:flgG_G_neg:flgF:flgA_cterm:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Amino Acid Metabolism:Genetic Information Processing:Translation:Cellular Processes:Cell Motility:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:Cellular processes:Chemotaxis and motility:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 360 "Phenylalanyl-tRNA synthetase alpha subunit:Transketolase:Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase:Phosphoglycerate dehydrogenase and related dehydrogenases:Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase:Tryptophanyl-tRNA synthetase:Ribosome recycling factor:3-oxoacyl-(acyl-carrier-protein) synthase:Aspartate/tyrosine/aromatic aminotransferase:Threonyl-tRNA synthetase:ATPase components of ABC transporters with duplicated ATPase domains:S-adenosylhomocysteine hydrolase:Uridylate kinase:Cystathionine beta-lyases/cystathionine gamma-synthases:Signal peptidase I:Membrane proteins related to metalloendopeptidases:Predicted membrane-associated Zn-dependent proteases 1:3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:Acetyl-CoA carboxylase beta subunit:Preprotein translocase subunit SecG:DNA segregation ATPase FtsK/SpoIIIE and related proteins:Phosphoserine aminotransferase:Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems:Predicted hydrolase of the alpha/beta superfamily:Outer membrane protein/protective antigen OMA87:Cell cycle control, cell division, chromosome partitioning:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fatty acid biosynthesis:Purine metabolism:Pyrimidine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Tryptophan metabolism:Selenocompound metabolism:Pyruvate metabolism:Propanoate metabolism:Methane metabolism:Carbon fixation in photosynthetic organisms:Carbon fixation pathways in prokaryotes:Vitamin B6 metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:TIGR00054:tktlase_bact:trpS:thrS:pheS:frr:accD:secG:ahcY:O_suc_HS_sulf:PGDH:serC_2:GAPDH-I:fabA:pyrH_bact:sigpep_I_bact:OM_YaeT:ABC_ABC_ChvD:Intracellular trafficking, secretion, and vesicular transport:Amino acid biosynthesis:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Global:Metabolism:Energy metabolism:Amino acids and amines:Glycolysis/gluconeogenesis:Pentose phosphate pathway:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Nucleotide and nucleoside interconversions:Protein synthesis:tRNA aminoacylation:Translation factors:Protein fate:Protein and peptide secretion and trafficking:Degradation of proteins, peptides, and glycopeptides:Metabolism:Aspartate family:Serine family:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 361 "Energy production and conversion:Integral membrane protein possibly involved in chromosome condensation:3-oxoacyl-(acyl-carrier-protein) synthase:Predicted enzyme with a TIM-barrel fold:Biotin-(acetyl-CoA carboxylase) ligase:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:Pseudouridylate synthases, 23S RNA-specific:Predicted hydrolase of the metallo-beta-lactamase superfamily:Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit:Multisubunit Na+/H+ antiporter, MnhC subunit:NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit:Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I):Multisubunit Na+/H+ antiporter, MnhG subunit:Putative transcriptional regulator, homolog of Bvg accessory factor:Multisubunit Na+/H+ antiporter, MnhE subunit:Multisubunit Na+/H+ antiporter, MnhF subunit:Chaperone required for the assembly of the mitochondrial F1-ATPase:Cell cycle control, cell division, chromosome partitioning:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Oxidative phosphorylation:Purine metabolism:Pantothenate and CoA biosynthesis:Biotin metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:rluA_subfam:TIGR00044:birA_ligase:baf:CPA3_mnhG_phaG:NuoI:Pantothenate and coenzyme A:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Metabolism of Cofactors and Vitamins:Global:Metabolism:Energy metabolism:Electron transport:Protein synthesis:tRNA and rRNA base modification:Protein fate:Protein modification and repair:Transport and binding proteins:Cations and iron carrying compounds:Unknown function:Enzymes of unknown specificity:Biosynthesis of cofactors, prosthetic groups, and carriers:Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 362 "Transcriptional regulator:ABC-type dipeptide/oligopeptide/nickel transport systems, permease components:MoxR-like ATPases:FOG: CheY-like receiver:ATPase components of various ABC-type transport systems, contain duplicated ATPase:Predicted ATPase:Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes:Beta-lactamase class C and other penicillin binding proteins:Predicted signal-transduction protein containing cAMP-binding and CBS domains:Nitric oxide reductase large subunit:Predicted membrane protein:Predicted membrane protein:Nitric oxide reductase activation protein:Amino acid transport and metabolism:Lipid transport and metabolism:Transcription:Inorganic ion transport and metabolism:Purine metabolism:Pyrimidine metabolism:Penicillin and cephalosporin biosynthesis:Glycerophospholipid metabolism:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:DNA replication:Mismatch repair:Homologous recombination:General function prediction only:Function unknown:Signal transduction mechanisms:dnaq:prismane_assoc:Defense mechanisms:Electron transport:Energy metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Metabolism:Replication and Repair:Genetic Information Processing:Biosynthesis of Other Secondary Metabolites:Nucleotide Metabolism:Lipid Metabolism:Degradation of DNA:Energy Metabolism:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized:DNA metabolism" 363 "3-oxoacyl-(acyl-carrier-protein) synthase:Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II:Sugar kinases, ribokinase family:Enoyl-[acyl-carrier-protein] reductase (NADH):Fe2+/Zn2+ uptake regulation proteins:3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases:Sugar (pentulose and hexulose) kinases:ABC-type multidrug transport system, ATPase component:TRAP-type C4-dicarboxylate transport system, large permease component:TRAP-type C4-dicarboxylate transport system, periplasmic component:ABC-type polysaccharide/polyol phosphate export systems, permease component:Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit:Transcriptional regulator/sugar kinase:Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit:Xylose isomerase:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Predicted acetyltransferase:TRAP-type C4-dicarboxylate transport system, small permease component:ABC-type xylose transport system, periplasmic component:ABC-type xylose transport system, permease component:TRAP-type mannitol/chloroaromatic compound transport system, small permease component:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Pentose phosphate pathway:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Fatty acid biosynthesis:Synthesis and degradation of ketone bodies:Valine leucine and isoleucine degradation:Butanoate metabolism:Metabolic pathways:Microbial metabolism in diverse environments:ABC transporters:Two-component system:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:dctM:dctP:XylB:fabA:pcaJ_scoB_fam:pcaI_scoA_fam:xylose_isom_A:xylF:phenyl_ABC_PedC:PQQ_ABC_bind:PQQ_ABC_ATP:Defense mechanisms:Information storage and processing:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Biosynthesis:Fatty acid and phospholipid metabolism:Sugars:Energy metabolism:Cellular processes and signaling:Metabolism:Poorly characterized:Metabolism:Metabolism:Global:Signal Transduction:Membrane Transport:Environmental Information Processing:Amino Acid Metabolism:Lipid Metabolism:Carbohydrate Metabolism" 364 "Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases:ABC-type amino acid transport/signal transduction systems, periplasmic component/domain:Metal-dependent hydrolases of the beta-lactamase superfamily I:Precorrin isomerase:Phage tail tube protein FII:TRAP-type mannitol/chloroaromatic compound transport system, large permease component:TRAP-type mannitol/chloroaromatic compound transport system, small permease component:Glucose dehydrogenase:Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Porphyrin and chlorophyll metabolism:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Signal transduction mechanisms:dctM:tail_tube:PQQ_syn_pqqB:PQQ_syn_pqqC:PQQ_enz_alc_DH:PQQ_PqqD:PQQ_CXXCW:ABC_peri_MoxJ_2:4cys_cytochr:Mobile and extrachromosomal element functions:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Metabolism:Metabolism:Global:Translation:Genetic Information Processing:Prophage functions:Metabolism of Cofactors and Vitamins:Biosynthesis of cofactors, prosthetic groups, and carriers:Other:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 365 "Diaminopimelate decarboxylase:Conserved domain frequently associated with peptide methionine sulfoxide reductase:Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain:ATP-dependent Zn proteases:Glycine/D-amino acid oxidases (deaminating):5,10-methylenetetrahydrofolate reductase:Glutathionylspermidine synthase:Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis):Multidrug resistance efflux pump:Beta-lactamase class C and other penicillin binding proteins:Transcriptional regulators:Predicted Fe-S protein:Metal-dependent hydrolase:Cytochrome c biogenesis factor:Predicted integral membrane protein:Amino acid transport and metabolism:Transcription:Replication, recombination and repair:Posttranslational modification, protein turnover, chaperones:Glycine serine and threonine metabolism:Arginine and proline metabolism:Glutathione metabolism:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:Function unknown:RNAse_H_YqgF:TIGR00357:fadh2:efflux_EmrB:FtsH_fam:soxB:degP_htrA_DO:cytochro_ccmI:Defense mechanisms:Cellular processes and signaling:Energy Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Metabolism of Cofactors and Vitamins:Global:Metabolism:Energy metabolism:Amino acids and amines:Electron transport:Protein fate:Degradation of proteins, peptides, and glycopeptides:Transport and binding proteins:Other:Cellular processes:Adaptations to atypical conditions:Unknown function:General:Amino acid biosynthesis:Aspartate family:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 366 "Energy production and conversion:Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]:Uncharacterized conserved protein:Acetolactate synthase, small (regulatory) subunit:Thioredoxin reductase:Zn-dependent protease with chaperone function:Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily):Periplasmic serine proteases (ClpP class):Predicted permease:Integral membrane protein, interacts with FtsH:5,10-methylenetetrahydrofolate reductase:Glutaredoxin and related proteins:ATP-dependent protease HslVU (ClpYQ), ATPase subunit:Disulfide bond chaperones of the HSP33 family:Preprotein translocase subunit SecB:Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Membrane-bound lytic murein transglycosylase:Uncharacterized protein conserved in bacteria:Uncharacterized protein conserved in bacteria:Protein affecting phage T7 exclusion by the F plasmid:Predicted ATPase:Uncharacterized protein conserved in bacteria:Predicted aspartyl protease:Predicted membrane protein:Uncharacterized protein involved in tellurite resistance:Uncharacterized protein conserved in bacteria:Uncharacterized conserved protein:Amino acid transport and metabolism:Coenzyme transport and metabolism:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pyrimidine metabolism:Valine leucine and isoleucine biosynthesis:Butanoate metabolism:C5-Branched dibasic acid metabolism:One carbon pool by folate:Methane metabolism:Carbon fixation pathways in prokaryotes:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Protein export:Bacterial secretion system:General function prediction only:Function unknown:Signal transduction mechanisms:acolac_lg:acolac_sm:hslU:fadh2:secB:TRX_reduct:hyp_HI0043:GRX_bact:clan_AA_DTGA:oxido_grp_1:Intracellular trafficking, secretion, and vesicular transport:Metabolism:Cellular processes and signaling:Pyruvate family:Aspartate family:Amino acid biosynthesis:Enzymes of unknown specificity:Unknown function:Degradation of proteins, peptides, and glycopeptides:Protein and peptide secretion and trafficking:Protein folding and stabilization:Protein fate:Electron transport:Energy metabolism:Metabolism:Metabolism:Global:Membrane Transport:Environmental Information Processing:Folding Sorting and Degradation:Genetic Information Processing:Metabolism of Cofactors and Vitamins:Amino Acid Metabolism:Nucleotide Metabolism:Energy Metabolism:Carbohydrate Metabolism:Poorly characterized" 367 "" 368 "Trehalose-6-phosphate synthase:Nucleoside-diphosphate-sugar epimerases:Multimeric flavodoxin WrbA:Integral membrane protein, interacts with FtsH:UDP-glucose 4-epimerase:UDP-glucose pyrophosphorylase:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted redox protein, regulator of disulfide bond formation:Transcriptional regulators:Trehalose-6-phosphatase:Predicted membrane protein:Molybdenum cofactor biosynthesis enzyme:Uncharacterized conserved protein:Uncharacterized protein involved in biosynthesis of c-type cytochromes:Putative salt-induced outer membrane protein:Uncharacterized protein conserved in bacteria:Uncharacterized stress protein (general stress protein 26):Glucose dehydrogenase:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Pentose phosphate pathway:Pentose and glucuronate interconversions:Galactose metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Glycerolipid metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:RNA polymerase:Sulfur relay system:General function prediction only:Function unknown:T6PP:galU:trehalose_OtsA:moaA:sigma70-ECF:PQQ_membr_DH:osmo_induc_OsmC:Metabolism:Cellular processes and signaling:Information storage and processing:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Cell envelope:Molybdopterin:Biosynthesis of cofactors, prosthetic groups, and carriers:Adaptations to atypical conditions:Detoxification:Cellular processes:Metabolism:Metabolism:Global:Folding Sorting and Degradation:Transcription:Genetic Information Processing:Lipid Metabolism:Poorly characterized:Carbohydrate Metabolism" 369 "Energy production and conversion:Adenylosuccinate lyase:F0F1-type ATP synthase, beta subunit:F0F1-type ATP synthase, alpha subunit:Ribosomal protein L13:Enolase:DNA-directed RNA polymerase, alpha subunit/40 kD subunit:Ribosomal protein L17:Uncharacterized conserved protein:F0F1-type ATP synthase, gamma subunit:Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A):Preprotein translocase subunit SecD:F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit):F0F1-type ATP synthase, subunit a:Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor):Preprotein translocase subunit YidC:F0F1-type ATP synthase, subunit b:F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein):Alanine racemase:TRAP-type C4-dicarboxylate transport system, large permease component:TRAP-type C4-dicarboxylate transport system, small permease component:TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component:Uncharacterized protein conserved in bacteria:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:D-Alanine metabolism:Methane metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Ribosome:RNA degradation:RNA polymerase:Protein export:Bacterial secretion system:Secondary metabolites biosynthesis, transport and catabolism:Function unknown:efp:L17:tig:alr:dctM:2A0604s01:purB:atpA:TIGR01033:atpD:eno:rplM_bact:ATP_synt_6_or_A:ATP_synt_delta:ATPsyn_F1gamma:ATP_synt_epsi:rpoA:yidC_oxa1_cterm:Intracellular trafficking, secretion, and vesicular transport:Carbohydrates, organic alcohols, and acids:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Genetic Information Processing:Transcription:Translation:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Energy metabolism:ATP-proton motive force interconversion:Glycolysis/gluconeogenesis:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Regulatory functions:DNA interactions:Transcription:DNA-dependent RNA polymerase:Protein synthesis:Ribosomal proteins: synthesis and modification:Translation factors:Protein fate:Protein folding and stabilization:Protein and peptide secretion and trafficking:Transport and binding proteins:Metabolism:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 370 "Glycosyltransferase:Kef-type K+ transport systems, membrane components:Zn-dependent hydrolases, including glyoxylases:Predicted permease:Chemotaxis protein histidine kinase and related kinases:FOG: CheY-like receiver:Chemotaxis signal transduction protein:Methyl-accepting chemotaxis protein:Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases):Serine acetyltransferase:Transglutaminase-like enzymes, putative cysteine proteases:Transcriptional regulator:Methylase of chemotaxis methyl-accepting proteins:TRAP-type C4-dicarboxylate transport system, large permease component:Chemotaxis protein; stimulates methylation of MCP proteins:Acyl-CoA dehydrogenases:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Uncharacterized protein conserved in bacteria:Signal transduction histidine kinase regulating C4-dicarboxylate transport system:Amino acid transport and metabolism:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Cell motility:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Cysteine and methionine metabolism:Pyruvate metabolism:Sulfur metabolism:Biosynthesis of unsaturated fatty acids:Metabolic pathways:Microbial metabolism in diverse environments:Two-component system:Bacterial chemotaxis:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:dctM:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:Carbohydrates, organic alcohols, and acids:Transport and binding proteins:Metabolism:Global:Cell Motility:Cellular Processes:Signal Transduction:Environmental Information Processing:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism" 371 "" 372 "Energy production and conversion:Arginyl-tRNA synthetase:Ornithine carbamoyltransferase:Ribose 5-phosphate isomerase:Triosephosphate isomerase:Phosphoribosylaminoimidazole (AIR) synthetase:Adenosylmethionine-8-amino-7-oxononanoate aminotransferase:2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway):Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit:Dihydrodipicolinate synthase/N-acetylneuraminate lyase:Predicted aminomethyltransferase related to GcvT:Helicase subunit of the DNA excision repair complex:DNA polymerase sliding clamp subunit (PCNA homolog):Transcription elongation factor:Predicted thioesterase:Predicted SAM-dependent methyltransferases:Putative transcriptional regulator, homolog of Bvg accessory factor:Uncharacterized conserved protein:Acetyltransferases, including N-acetylases of ribosomal proteins:Holliday junction resolvasome, helicase subunit:Uncharacterized protein with SCP/PR1 domains:Uncharacterized protein conserved in bacteria:Predicted ATPase (AAA+ superfamily):Uncharacterized protein, similar to the N-terminal domain of Lon protease:NADH:ubiquinone oxidoreductase 17.2 kD subunit:Predicted integral membrane protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Fructose and mannose metabolism:Oxidative phosphorylation:Purine metabolism:Pyrimidine metabolism:Lysine biosynthesis:Inositol phosphate metabolism:Carbon fixation in photosynthetic organisms:Pantothenate and CoA biosynthesis:Aminoacyl-tRNA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:DNA replication:Nucleotide excision repair:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:rpiA:tim:argS:uvrb:ruvB:orni_carb_tr:dnan:baf:dapA:purM:gyrB:greA:ygfZ_signature:Poorly characterized:Carbohydrate Metabolism:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Genetic Information Processing:Translation:Replication and Repair:Global:Metabolism:Energy metabolism:Glycolysis/gluconeogenesis:Pentose phosphate pathway:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Transcription:Transcription factors:Protein synthesis:tRNA aminoacylation:tRNA and rRNA base modification:Amino acid biosynthesis:Aspartate family:Glutamate family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 373 "" 374 "Glutamate-1-semialdehyde aminotransferase:Undecaprenyl pyrophosphate synthase:Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase):Glutamine synthetase:Fatty acid/phospholipid biosynthesis enzyme:UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:SAM-dependent methyltransferases:Sugar kinases, ribokinase family:CDP-diglyceride synthetase:Uncharacterized membrane protein, putative virulence factor:ABC-type transport system involved in resistance to organic solvents, permease component:Cell division protein FtsI/penicillin-binding protein 2:UDP-N-acetylmuramyl tripeptide synthase:UDP-N-acetylmuramyl pentapeptide synthase:Polyphosphate kinase:Predicted UDP-glucose 6-dehydrogenase:ADP-ribose pyrophosphatase:UDP-glucose 4-epimerase:D-Tyr-tRNAtyr deacylase:Membrane protein involved in the export of O-antigen and teichoic acid:UTP:GlnB (protein PII) uridylyltransferase:ABC-type uncharacterized transport system, permease component:ABC-type uncharacterized transport system, permease component:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Inorganic ion transport and metabolism:Pentose and glucuronate interconversions:Fructose and mannose metabolism:Galactose metabolism:Ascorbate and aldarate metabolism:Oxidative phosphorylation:Purine metabolism:Alanine aspartate and glutamate metabolism:Lysine biosynthesis:Arginine and proline metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Peptidoglycan biosynthesis:Glycerolipid metabolism:Glycerophospholipid metabolism:Porphyrin and chlorophyll metabolism:Terpenoid backbone biosynthesis:Nitrogen metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:ABC transporters:Two-component system:RNA degradation:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:uppS:TIGR00056:plsX:TIGR00256:mraY:murE:murF:purK:galE:UTase_glnD:mviN:NDP-sugDHase:poly_P_kin:Cell envelope:Carbohydrate Metabolism:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Cofactors and Vitamins:Metabolism of Terpenoids and Polyketides:Genetic Information Processing:Folding Sorting and Degradation:Environmental Information Processing:Membrane Transport:Signal Transduction:Global:Metabolism:Central intermediary metabolism:Phosphorus compounds:Energy metabolism:Sugars:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis:Regulatory functions:Protein interactions:Protein synthesis:tRNA aminoacylation:Hypothetical proteins:Conserved:Unknown function:General:Metabolism:Biosynthesis and degradation of murein sacculus and peptidoglycan:Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides:Information storage and processing:Cellular processes and signaling:Metabolism:Poorly characterized" 375 "Dihydroorotate dehydrogenase:Dihydroorotase:Di- and tricarboxylate transporters:GMP synthase - Glutamine amidotransferase domain:Glycine/D-amino acid oxidases (deaminating):Predicted flavoproteins:Uncharacterized protein conserved in bacteria:Predicted permease, DMT superfamily:Amino acid transport and metabolism:Nucleotide transport and metabolism:Inorganic ion transport and metabolism:Pyrimidine metabolism:Phenylalanine metabolism:Nitrogen metabolism:Metabolic pathways:General function prediction only:Function unknown:TIGR00275:pyrC_dimer:pyrD_sub2:Enzymes of unknown specificity:Energy Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Global:Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesis:Unknown function:Metabolism:Metabolism:Poorly characterized" 376 "DNA mismatch repair enzyme (predicted ATPase):Replication, recombination and repair:Mismatch repair:mutl:Information storage and processing:DNA metabolism:Replication and Repair:Genetic Information Processing:DNA replication, recombination, and repair" 377 "Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases:Fe2+ transport system protein B:cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases:Uncharacterized protein conserved in bacteria:Fe2+ transport system protein A:DNA-binding HTH domain-containing proteins:Outer membrane protein W:Cell wall hydrolyses involved in spore germination:Predicted membrane protein:Signal transduction histidine kinase:Lipid transport and metabolism:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Propanoate metabolism:Metabolic pathways:Function unknown:Signal transduction mechanisms:small_GTP:Poorly characterized:Metabolism:Cellular processes and signaling:Information storage and processing:General:Unknown function:Metabolism:Global:Metabolism:Carbohydrate Metabolism" 378 "" 379 "Site-specific DNA methylase:Glycosyltransferase:ATPase components of ABC transporters with duplicated ATPase domains:Periplasmic serine proteases (ClpP class):Zn-dependent alcohol dehydrogenases:ABC-type spermidine/putrescine transport system, permease component I:Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Posttranslational modification, protein turnover, chaperones:Glycolysis / Gluconeogenesis:Fatty acid metabolism:Tyrosine metabolism:Chloroalkane and chloroalkene degradation:Naphthalene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Mismatch repair:General function prediction only:Function unknown:Signal transduction mechanisms:Intracellular trafficking, secretion, and vesicular transport:Cellular processes and signaling:Carbohydrate Metabolism:Lipid Metabolism:Amino Acid Metabolism:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Replication and Repair:Global:Metabolism:Information storage and processing:Metabolism:Metabolism:Poorly characterized" 380 "Energy production and conversion:(acyl-carrier-protein) S-malonyltransferase:Predicted membrane metal-binding protein:Heme/copper-type cytochrome/quinol oxidases, subunit 1:NAD-dependent aldehyde dehydrogenases:Predicted transcriptional regulators:Nitrate/nitrite transporter:Uncharacterized enzyme involved in inositol metabolism:Outer membrane receptor for monomeric catechols:Site-specific recombinase XerD:Carbohydrate transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose and glucuronate interconversions:Ascorbate and aldarate metabolism:Fatty acid metabolism:Oxidative phosphorylation:Valine leucine and isoleucine degradation:Lysine degradation:Arginine and proline metabolism:Histidine metabolism:Tryptophan metabolism:beta-Alanine metabolism:Glycerolipid metabolism:Inositol phosphate metabolism:Pyruvate metabolism:Chloroalkane and chloroalkene degradation:Propanoate metabolism:Limonene and pinene degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:General function prediction only:ComEC_N-term:TonB-siderophor:CtaD_CoxA:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Terpenoids and Polyketides:Metabolism of Other Amino Acids:Amino Acid Metabolism:Lipid Metabolism:Energy Metabolism:Metabolism:Carbohydrate Metabolism:Energy metabolism:Electron transport:Transport and binding proteins:Porins:Unknown function:General:Information storage and processing:Metabolism:Poorly characterized:Metabolism" 381 "Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase:dGTP triphosphohydrolase:Orotidine-5'-phosphate decarboxylase:Phosphopantothenoylcysteine synthetase/decarboxylase:DNA polymerase III, alpha subunit:ATPase involved in DNA replication initiation:Signal transduction histidine kinase:Predicted xylanase/chitin deacetylase:3-dehydroquinate dehydratase II:NAD-dependent protein deacetylases, SIR2 family:Predicted nucleoside-diphosphate sugar epimerases:Tellurite resistance protein and related permeases:Uncharacterized conserved protein:DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog:Predicted Rossmann fold nucleotide-binding protein:Transcriptional regulator/sugar kinase:Cytochrome P450:Uncharacterized conserved protein:Uncharacterized conserved protein:Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain:Lysophospholipase:Transthyretin-like protein:DNA polymerase III, gamma/tau subunits:NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding:Outer membrane protein and related peptidoglycan-associated (lipo)proteins:Uncharacterized protein, possibly involved in glyoxylate utilization:Flp pilus assembly protein, secretin CpaC:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid metabolism:Purine metabolism:Pyrimidine metabolism:Valine leucine and isoleucine degradation:Valine leucine and isoleucine biosynthesis:Tryptophan metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Amino sugar and nucleotide sugar metabolism:Aminobenzoate degradation:Nicotinate and nicotinamide metabolism:Pantothenate and CoA biosynthesis:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:RNA polymerase:DNA replication:Mismatch repair:Homologous recombination:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:Signal transduction mechanisms:DnaA:coaBC_dfp:polc:TIGR00730:ahpD_dom:aroQ:dGTP_triPase:pyrF:PpsR-CrtJ:TIGR02246:dnaX_nterm:sigma70-ECF:hdxy_isourate:UHCUDC:ura-cupin:Intracellular trafficking, secretion, and vesicular transport:Poorly characterized:Carbohydrate Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Cofactors and Vitamins:Xenobiotics Biodegradation and Metabolism:Genetic Information Processing:Transcription:Replication and Repair:Environmental Information Processing:Signal Transduction:Global:Metabolism:Energy metabolism:Photosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Other:Nucleotide and nucleoside interconversions:Pyrimidine ribonucleotide biosynthesis:DNA metabolism:DNA replication, recombination, and repair:Hypothetical proteins:Conserved:Unknown function:General:Amino acid biosynthesis:Aromatic amino acid family:Biosynthesis of cofactors, prosthetic groups, and carriers:Pantothenate and coenzyme A:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 382 "Energy production and conversion:Purine nucleoside phosphorylase:Delta-aminolevulinic acid dehydratase:Tryptophan synthase beta chain:Phosphoribosylanthranilate isomerase:Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family:Translation elongation factors (GTPases):Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins:2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases:3-deoxy-D-manno-octulosonic-acid transferase:Cytochrome c peroxidase:Predicted transcriptional regulator:Uncharacterized membrane-bound protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Purine metabolism:Glycine serine and threonine metabolism:Cysteine and methionine metabolism:Phenylalanine tyrosine and tryptophan biosynthesis:Lipopolysaccharide biosynthesis:Polycyclic aromatic hydrocarbon degradation:Naphthalene degradation:Porphyrin and chlorophyll metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Function unknown:trpB:salvage_mtnA:rrf2_super:apt:MTAP:Cellular processes and signaling:Information storage and processing:Aspartate family:Aromatic amino acid family:Amino acid biosynthesis:General:Unknown function:Salvage of nucleosides and nucleotides:Purines, pyrimidines, nucleosides, and nucleotides:Metabolism:Metabolism:Global:Xenobiotics Biodegradation and Metabolism:Metabolism of Cofactors and Vitamins:Glycan Biosynthesis and Metabolism:Amino Acid Metabolism:Poorly characterized:Nucleotide Metabolism:Metabolism" 383 "Energy production and conversion:DNA-directed RNA polymerase, beta' subunit/160 kD subunit:Pseudouridine synthase:Phosphate/sulphate permeases:Guanosine polyphosphate pyrophosphohydrolases/synthetases:3-oxoacyl-[acyl-carrier-protein] synthase III:ABC-type branched-chain amino acid transport systems, ATPase component:Carbamoylphosphate synthase large subunit (split gene in MJ):UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase:Branched-chain amino acid ABC-type transport system, permease components:dsRNA-specific ribonuclease:ABC-type Fe3+-siderophore transport system, permease component:Cystathionine beta-lyases/cystathionine gamma-synthases:Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit:UDP-N-acetylmuramyl tripeptide synthase:UDP-N-acetylmuramyl pentapeptide synthase:ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components:Multisubunit Na+/H+ antiporter, MnhE subunit:Uncharacterized conserved protein:ABC-type hemin transport system, periplasmic component:Uncharacterized conserved protein:Amino acid transport and metabolism:Nucleotide transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Fatty acid biosynthesis:Purine metabolism:Pyrimidine metabolism:Alanine aspartate and glutamate metabolism:Cysteine and methionine metabolism:Lysine biosynthesis:Selenocompound metabolism:Peptidoglycan biosynthesis:Sulfur metabolism:Metabolic pathways:Biosynthesis of secondary metabolites:ABC transporters:RNA polymerase:Function unknown:Signal transduction mechanisms:TruB:mraY:spoT_relA:fabH:murE:murF:CPSaseII_lrg:RNaseIII:rpoC_TIGR:Poorly characterized:Energy Metabolism:Lipid Metabolism:Nucleotide Metabolism:Amino Acid Metabolism:Metabolism of Other Amino Acids:Glycan Biosynthesis and Metabolism:Genetic Information Processing:Transcription:Environmental Information Processing:Membrane Transport:Global:Metabolism:Fatty acid and phospholipid metabolism:Biosynthesis:Purines, pyrimidines, nucleosides, and nucleotides:Pyrimidine ribonucleotide biosynthesis:Transcription:DNA-dependent RNA polymerase:RNA processing:Protein synthesis:tRNA and rRNA base modification:Cellular processes:Adaptations to atypical conditions:Cell envelope:Biosynthesis and degradation of murein sacculus and peptidoglycan:Information storage and processing:Cellular processes and signaling:Metabolism:Metabolism" 384 "Energy production and conversion:Arginase/agmatinase/formimionoglutamate hydrolase, arginase family:Phosphoglucomutase:Predicted EndoIII-related endonuclease:Putative translation initiation inhibitor, yjgF family:Leucyl aminopeptidase:CTP synthase (UTP-ammonia lyase):Lipoprotein signal peptidase:UDP-N-acetylmuramoylalanine-D-glutamate ligase:Enoyl-CoA hydratase/carnithine racemase:Lactate dehydrogenase and related dehydrogenases:Acyl carrier protein phosphodiesterase:3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase:Amidases related to nicotinamidase:Uncharacterized conserved protein:Uncharacterized protein conserved in bacteria:Nicotinic acid phosphoribosyltransferase:Transcriptional regulators:Beta-lactamase class C and other penicillin binding proteins:Methylmalonyl-CoA mutase, N-terminal domain/subunit:DNA-binding HTH domain-containing proteins:Putative hemolysin:Uncharacterized protein conserved in bacteria:Amino acid transport and metabolism:Nucleotide transport and metabolism:Carbohydrate transport and metabolism:Coenzyme transport and metabolism:Lipid transport and metabolism:Translation, ribosomal structure and biogenesis:Transcription:Replication, recombination and repair:Cell wall/membrane/envelope biogenesis:Inorganic ion transport and metabolism:Glycolysis / Gluconeogenesis:Pentose phosphate pathway:Galactose metabolism:Fatty acid metabolism:Purine metabolism:Pyrimidine metabolism:Valine leucine and isoleucine degradation:Geraniol degradation:Lysine degradation:Arginine and proline metabolism:Benzoate degradation:Tryptophan metabolism:beta-Alanine metabolism:D-Glutamine and D-glutamate metabolism:Glutathione metabolism:Starch and sucrose metabolism:Amino sugar and nucleotide sugar metabolism:Streptomycin biosynthesis:Peptidoglycan biosynthesis:Pyruvate metabolism:Aminobenzoate degradation:Glyoxylate and dicarboxylate metabolism:Propanoate metabolism:Butanoate metabolism:Carbon fixation pathways in prokaryotes:Nicotinate and nicotinamide metabolism:Limonene and pinene degradation:Caprolactam degradation:Metabolic pathways:Biosynthesis of secondary metabolites:Microbial metabolism in diverse environments:Two-component system:Protein export:Base excision repair:Secondary metabolites biosynthesis, transport and catabolism:General function prediction only:Function unknown:lspA:PyrG:acid_CoA_mut_C:nth:murD:agmatinase:bisphos_cysQ:NAPRTase:Intracellular trafficking, secretion, and vesicular transport:Defense mechanisms:Global:Cellular processes and signaling:Signal Transduction:Environmental Information Processing:Information storage and processing:Replication and Repair:Biosynthesis and degradation of murein sacculus and peptidoglycan:Folding Sorting and Degradation:Cell envelope:Pyridine nucleotides:Biosynthesis of cofactors, prosthetic groups, and carriers:Genetic Information Processing:Protein and peptide secretion and trafficking:Protein fate:Xenobiotics Biodegradation and Metabolism:Biosynthesis of Other Secondary Metabolites:DNA replication, recombination, and repair:Metabolism of Terpenoids and Polyketides:DNA metabolism:Metabolism of Cofactors and Vitamins:Metabolism:Glycan Biosynthesis and Metabolism:Metabolism of Other Amino Acids:Amino Acid Metabolism:Nucleotide Metabolism:Lipid Metabolism:Pyrimidine ribonucleotide biosynthesis:Energy Metabolism:Purines, pyrimidines, nucleosides, and nucleotides:Sulfur metabolism:Central intermediary metabolism:Poorly characterized:Carbohydrate Metabolism:Metabolism:Metabolism"