MMP0228 MMP0228 N2;N2-dimethylguanosine tRNA methyltransferase (NCBI)

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Methanococcus maripaludis S2

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Summary

Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
MMP0228 MMP0228 trm1 trm1, trmI, MMP0228 N2;N2-dimethylguanosine tRNA methyltransferase (NCBI) tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase) 236852 237973 + 15466049

Regulatory Modules

Residual Expression Plot
mmp-bicluster_0021 0.45
mmp-bicluster_0042 0.38

XReference

Uniprot NCBI Gene NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro
P0CW65 2762025 NP_987348.1;WP_011170172.1; 45357791 532415 CAF29784 IPR029063, IPR002905, IPR022923

Mutations

Transposon mutants

Title Insert TAG Module
MMP0228

Homology

Orthologues Paralogues

Functions

Catalytic Activity COG EC Description Protein families TIGR Roles
2 S-adenosyl-L-methionine + guanine(26) in tRNA = 2 S-adenosyl-L-homocysteine + N(2)-dimethylguanine(26) in tRNA. {ECO:0000255|HAMAP-Rule:MF_00290}. (J) COG1867 | N2,N2-dimethylguanosine tRNA methyltransferase (2.1.1.32) tRNA (guanine-N(2)-)-methyltransferase. Class I-like SAM-binding methyltransferase superfamily, Trm1 family Protein synthesis:tRNA and rRNA base modification

Essentiality

L1.Cm.T1 L1.Cm.T2 L1.cN.T1 L1.cN.T2 L1.T0 L2.Cm.T1 L2.Cm.T2 L2.cN.T1 L2.cN.T2 L2.T0
30 27 8 6 30 13 16 7 9 14

Product Synonyms

Product (LegacyBRC) Product (RefSeq)

Operon

Refseq

GI Number Accession Blast Conserved Domains
45357791 NP_987348.1 Run

GO Terms

String Network

Link to STRINGS STRINGS Network
MMP0228

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