MMP0697 MMP0697 Leucyl-tRNA synthetase (NCBI)

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Methanococcus maripaludis S2

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Summary

Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
MMP0697 MMP0697 leuS leuS, MMP0697 Leucyl-tRNA synthetase (NCBI) Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) 686587 689454 + 15466049

Regulatory Modules

Residual Expression Plot
mmp-bicluster_0143 0.30

XReference

Uniprot NCBI Gene NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro EggNOG
Q6LZD2 2761186 NP_987817.1; 45358260 532890 CAF30253 IPR001412, IPR002300, IPR020791, IPR004493, IPR013155, IPR015413, IPR014729, IPR009080, IPR009008 COG0495

Mutations

Line Position Effect Impact Class Percent Frequency Sample Title
UE3 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 UE3.152.09.M03 BX950229-MMP0697-687745-UE3.152.09.M03
UE3 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 55_Mmp_55_9-48491487 BX950229-MMP0697-687745-55_Mmp_55_9-48491487
UE2 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 TG_UE2 BX950229-MMP0697-687745-TG_UE2
HA2 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 EG_HA2_15 BX950229-MMP0697-687745-EG_HA2_15
UE3 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 67_Mmp_67_UA315209-48706724 BX950229-MMP0697-687745-67_Mmp_67_UA315209-48706724
HE2 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 TG_HE2 BX950229-MMP0697-687745-TG_HE2
UE3 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 UE3.152.03.M01 BX950229-MMP0697-687745-UE3.152.03.M01
UE3 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 UE3.152.10.M01 BX950229-MMP0697-687745-UE3.152.10.M01
HR1 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 TG_HR1 BX950229-MMP0697-687745-TG_HR1
HS3 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 EG_HS3_45 BX950229-MMP0697-687745-EG_HS3_45

Transposon mutants

Title Insert TAG Module
MMP0697

Homology

Orthologues Paralogues

Functions

Catalytic Activity COG EC Description Protein families TIGR Roles
ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu). {ECO:0000255|HAMAP-Rule:MF_00049}. (J) COG495 | Leucyl-tRNA synthetase (6.1.1.4) Leucine--tRNA ligase. Class-I aminoacyl-tRNA synthetase family Protein synthesis:tRNA aminoacylation

Essentiality

L1.Cm.T1 L1.Cm.T2 L1.cN.T1 L1.cN.T2 L1.T0 L2.Cm.T1 L2.Cm.T2 L2.cN.T1 L2.cN.T2 L2.T0
0 0 1 0 11 1 1 0 0 3

Product Synonyms

Product (LegacyBRC) Product (RefSeq)

Operon

Refseq

GI Number Accession Blast Conserved Domains
45358260 NP_987817.1 Run

GO Terms

String Network

Link to STRINGS STRINGS Network
MMP0697

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