Methanococcus maripaludis S2 Module 113 Residual: 0.27

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Summary

Residual: 0.27 Score: -15.8541 version: mmp_cmonkey_11_Oct_11

Members

MMP0058 coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin reductase (NCBI)

Details for MMP0058 - coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin reductase (NCBI)

GO Terms: GO:0018537

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0058

Tuberculist Genomic Region

MMP1695 F420-non-reducing hydrogenase subunit (NCBI)

Details for MMP1695 - F420-non-reducing hydrogenase subunit (NCBI)

GO Terms: GO:0006120, GO:0008137, GO:0050454

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1695

Tuberculist Genomic Region

MMP0372 F420-dependent methylenetetrahydromethanopterin dehydrogenase (NCBI)

Details for MMP0372 - F420-dependent methylenetetrahydromethanopterin dehydrogenase (NCBI)

GO Terms: GO:0015948, GO:0008901, GO:0030268

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0372

Tuberculist Genomic Region

MMP1696 F420-non-reducing hydrogenase subunit delta (NCBI)

Details for MMP1696 - F420-non-reducing hydrogenase subunit delta (NCBI)

GO Terms: GO:0015948

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1696

Tuberculist Genomic Region

MMP0817 coenzyme F420-reducing hydrogenase subunit beta (NCBI)

Details for MMP0817 - coenzyme F420-reducing hydrogenase subunit beta (NCBI)

GO Terms: GO:0050454

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0817

Tuberculist Genomic Region

MMP1697 heterodisulfide reductase, subunit A (NCBI)

Details for MMP1697 - heterodisulfide reductase, subunit A (NCBI)

GO Terms: GO:0006118, GO:0051912, GO:0009055, GO:0050660, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1697

Tuberculist Genomic Region

MMP1382 coenzyme F420-reducing hydrogenase subunit alpha (NCBI)

Details for MMP1382 - coenzyme F420-reducing hydrogenase subunit alpha (NCBI)

GO Terms: GO:0006118, GO:0008901, GO:0016151

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1382

Tuberculist Genomic Region

MMP1297 formate dehydrogenase beta subunit (NCBI)

Details for MMP1297 - formate dehydrogenase beta subunit (NCBI)

GO Terms: GO:0006118, GO:0009326, GO:0008863, GO:0009055, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1297

Tuberculist Genomic Region

MMP1383 coenzyme F420-reducing hydrogenase delta subunit (NCBI)

Details for MMP1383 - coenzyme F420-reducing hydrogenase delta subunit (NCBI)

GO Terms: GO:0006464, GO:0008047, GO:0008233

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1383

Tuberculist Genomic Region

MMP1298 formate dehydrogenase alpha subunit (NCBI)

Details for MMP1298 - formate dehydrogenase alpha subunit (NCBI)

GO Terms: GO:0006118, GO:0015942, GO:0009326, GO:0008863, GO:0030151

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1298

Tuberculist Genomic Region

MMP1384 coenzyme F420-reducing hydrogenase subunit gamma (NCBI)

Details for MMP1384 - coenzyme F420-reducing hydrogenase subunit gamma (NCBI)

GO Terms: GO:0006120, GO:0051539, GO:0051536, GO:0050454, GO:0008137

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1384

Tuberculist Genomic Region

MMP1299 carbonic anhydrase (NCBI)

Details for MMP1299 - carbonic anhydrase (NCBI)

GO Terms: GO:0015976, GO:0008270, GO:0004089

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1299

Tuberculist Genomic Region

MMP1691 tungsten containing formylmethanofuran dehydrogenase subunit B (NCBI)

Details for MMP1691 - tungsten containing formylmethanofuran dehydrogenase subunit B (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1691

Tuberculist Genomic Region

MMP1300 hypothetical protein (NCBI)

Details for MMP1300 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1300

Tuberculist Genomic Region

MMP1692 polyferredoxin, associated with F420-non-reducing hydrogenase (NCBI)

Details for MMP1692 - polyferredoxin, associated with F420-non-reducing hydrogenase (NCBI)

GO Terms: GO:0006118, GO:0009055, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1692

Tuberculist Genomic Region

MMP1301 Formate transporter (NCBI)

Details for MMP1301 - Formate transporter (NCBI)

GO Terms: GO:0006810, GO:0016020, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1301

Tuberculist Genomic Region

MMP1693 F420 non-reducing hydrogenase subunit (NCBI)

Details for MMP1693 - F420 non-reducing hydrogenase subunit (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1693

Tuberculist Genomic Region

MMP1302 hypothetical protein (NCBI)

Details for MMP1302 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1302

Tuberculist Genomic Region

MMP1694 F420-non-reducing hydrogenase subunit alpha (NCBI)

Details for MMP1694 - F420-non-reducing hydrogenase subunit alpha (NCBI)

GO Terms: GO:0006118, GO:0008901, GO:0016151

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1694

Tuberculist Genomic Region

MMP1385 coenzyme F420-reducing hydrogenase subunit beta (NCBI)

Details for MMP1385 - coenzyme F420-reducing hydrogenase subunit beta (NCBI)

GO Terms: GO:0050454

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1385

Tuberculist Genomic Region

Displaying 1 - 20 of 20

Motifs

Motif 1: e-value: 4 e-value: 91

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0719

predicted transcriptional regluator (NCBI)
 up-regulates 0.32

MMP0719

MMP0629

conserved hypothetical archaeal protein (NCBI)
 down-regulates -0.31

MMP0629

H2

 down-regulates -0.24

H2

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)

MMP1304

Response regulator receiver (NCBI)
 up-regulates 0.16

MMP0052

MMP1304

MMP0018

Transcriptional regulator, LysR Family Member (NCBI)

MMP1712

Transcriptional regulator, LysR Family Member (NCBI)
 up-regulates 0.10

MMP0018

MMP1712

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0006464 cellular protein modification process 5 0.03 1 0.0260
BP GO:0036211 protein modification process 5 0.03 1 0.0260
BP GO:0043412 macromolecule modification 5 0.03 1 0.0260
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0008901 ferredoxin hydrogenase activity 3 0.06 2 0.0012
MF GO:0016699 oxidoreductase activity, acting on hydro... 3 0.06 2 0.0012
MF GO:0016730 oxidoreductase activity, acting on iron-... 5 0.10 2 0.0039
MF GO:0051536 iron-sulfur cluster binding 67 1.39 5 0.0087
MF GO:0051540 metal cluster binding 67 1.39 5 0.0087
MF GO:0003824 catalytic activity 298 6.17 10 0.0437

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