Methanococcus maripaludis S2 Module 114 Residual: 0.23

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Summary

Residual: 0.23 Score: -21.6995 version: mmp_cmonkey_11_Oct_11

Members

MMP0058 coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin reductase (NCBI)

Details for MMP0058 - coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin reductase (NCBI)

GO Terms: GO:0018537

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0058

Tuberculist Genomic Region

MMP1384 coenzyme F420-reducing hydrogenase subunit gamma (NCBI)

Details for MMP1384 - coenzyme F420-reducing hydrogenase subunit gamma (NCBI)

GO Terms: GO:0006120, GO:0051539, GO:0051536, GO:0050454, GO:0008137

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1384

Tuberculist Genomic Region

MMP0372 F420-dependent methylenetetrahydromethanopterin dehydrogenase (NCBI)

Details for MMP0372 - F420-dependent methylenetetrahydromethanopterin dehydrogenase (NCBI)

GO Terms: GO:0015948, GO:0008901, GO:0030268

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0372

Tuberculist Genomic Region

MMP1691 tungsten containing formylmethanofuran dehydrogenase subunit B (NCBI)

Details for MMP1691 - tungsten containing formylmethanofuran dehydrogenase subunit B (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1691

Tuberculist Genomic Region

MMP0817 coenzyme F420-reducing hydrogenase subunit beta (NCBI)

Details for MMP0817 - coenzyme F420-reducing hydrogenase subunit beta (NCBI)

GO Terms: GO:0050454

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0817

Tuberculist Genomic Region

MMP1692 polyferredoxin, associated with F420-non-reducing hydrogenase (NCBI)

Details for MMP1692 - polyferredoxin, associated with F420-non-reducing hydrogenase (NCBI)

GO Terms: GO:0006118, GO:0009055, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1692

Tuberculist Genomic Region

MMP0822 coenzyme F420-non-reducing hydrogenase subunit gamma (NCBI)

Details for MMP0822 - coenzyme F420-non-reducing hydrogenase subunit gamma (NCBI)

GO Terms: GO:0006120, GO:0008137, GO:0051539

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0822

Tuberculist Genomic Region

MMP1693 F420 non-reducing hydrogenase subunit (NCBI)

Details for MMP1693 - F420 non-reducing hydrogenase subunit (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1693

Tuberculist Genomic Region

MMP0824 coenzyme F420-non-reducing hydrogenase subunit beta (NCBI)

Details for MMP0824 - coenzyme F420-non-reducing hydrogenase subunit beta (NCBI)

GO Terms: GO:0006118, GO:0009055, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0824

Tuberculist Genomic Region

MMP1694 F420-non-reducing hydrogenase subunit alpha (NCBI)

Details for MMP1694 - F420-non-reducing hydrogenase subunit alpha (NCBI)

GO Terms: GO:0006118, GO:0008901, GO:0016151

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1694

Tuberculist Genomic Region

MMP1378 hypothetical protein (NCBI)

Details for MMP1378 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1378

Tuberculist Genomic Region

MMP1695 F420-non-reducing hydrogenase subunit (NCBI)

Details for MMP1695 - F420-non-reducing hydrogenase subunit (NCBI)

GO Terms: GO:0006120, GO:0008137, GO:0050454

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1695

Tuberculist Genomic Region

MMP1382 coenzyme F420-reducing hydrogenase subunit alpha (NCBI)

Details for MMP1382 - coenzyme F420-reducing hydrogenase subunit alpha (NCBI)

GO Terms: GO:0006118, GO:0008901, GO:0016151

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1382

Tuberculist Genomic Region

MMP1696 F420-non-reducing hydrogenase subunit delta (NCBI)

Details for MMP1696 - F420-non-reducing hydrogenase subunit delta (NCBI)

GO Terms: GO:0015948

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1696

Tuberculist Genomic Region

MMP1383 coenzyme F420-reducing hydrogenase delta subunit (NCBI)

Details for MMP1383 - coenzyme F420-reducing hydrogenase delta subunit (NCBI)

GO Terms: GO:0006464, GO:0008047, GO:0008233

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1383

Tuberculist Genomic Region

MMP1697 heterodisulfide reductase, subunit A (NCBI)

Details for MMP1697 - heterodisulfide reductase, subunit A (NCBI)

GO Terms: GO:0006118, GO:0051912, GO:0009055, GO:0050660, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1697

Tuberculist Genomic Region

Displaying 1 - 16 of 16

Motifs

Motif 1: e-value: 0.0031 e-value: 0.15

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)

MMP1304

Response regulator receiver (NCBI)
 up-regulates 0.34

MMP0052

MMP1304

H2

 down-regulates -0.34

H2

MMP1100

putative transricptional regulator (NCBI)
 up-regulates 0.29

MMP1100

MMP1023

Transcriptional regulator, TetR Family Member (NCBI)
 down-regulates -0.14

MMP1023

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0006464 cellular protein modification process 5 0.03 1 0.0260
BP GO:0036211 protein modification process 5 0.03 1 0.0260
BP GO:0043412 macromolecule modification 5 0.03 1 0.0260
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0016491 oxidoreductase activity 78 1.41 7 0.0002
MF GO:0046995 oxidoreductase activity, acting on hydro... 8 0.14 3 0.0003
MF GO:0051536 iron-sulfur cluster binding 67 1.21 6 0.0006
MF GO:0051540 metal cluster binding 67 1.21 6 0.0006
MF GO:0008901 ferredoxin hydrogenase activity 3 0.05 2 0.0009
MF GO:0016699 oxidoreductase activity, acting on hydro... 3 0.05 2 0.0009
MF GO:0016730 oxidoreductase activity, acting on iron-... 5 0.09 2 0.0030

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