Methanococcus maripaludis S2 Module 123 Residual: 0.43

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Summary

Residual: 0.43 Score: -9.30279 version: mmp_cmonkey_11_Oct_11

Members

MMP0820 coenzyme F420-reducing hydrogenase subunit alpha (NCBI)

Details for MMP0820 - coenzyme F420-reducing hydrogenase subunit alpha (NCBI)

GO Terms: GO:0006118, GO:0008901, GO:0016151

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0820

Tuberculist Genomic Region

MMP1135 Flavodoxin:Beta-lactamase-like (NCBI)

Details for MMP1135 - Flavodoxin:Beta-lactamase-like (NCBI)

GO Terms: GO:0010181, GO:0016491, GO:0016787

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1135

Tuberculist Genomic Region

MMP1251 Conserved Hypothetical Protein with 2 CBS domains. (NCBI)

Details for MMP1251 - Conserved Hypothetical Protein with 2 CBS domains. (NCBI)

GO Terms: GO:0008152, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1251

Tuberculist Genomic Region

MMP1136 Rubrerythrin (NCBI)

Details for MMP1136 - Rubrerythrin (NCBI)

GO Terms: GO:0006118, GO:0006879, GO:0046914, GO:0008199, GO:0016491

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1136

Tuberculist Genomic Region

MMP1252 CBS domain (NCBI)

Details for MMP1252 - CBS domain (NCBI)

GO Terms: GO:0008152, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1252

Tuberculist Genomic Region

MMP1223 conserved hypothetical archaeal protein (NCBI)

Details for MMP1223 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1223

Tuberculist Genomic Region

MMP1661 hypothetical protein (NCBI)

Details for MMP1661 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1661

Tuberculist Genomic Region

MMP1229 conserved hypothetical protein (NCBI)

Details for MMP1229 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1229

Tuberculist Genomic Region

MMP1685 conserved hypothetical protein (NCBI)

Details for MMP1685 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1685

Tuberculist Genomic Region

MMP1347 archaeal histone B (NCBI)

Details for MMP1347 - archaeal histone B (NCBI)

GO Terms: GO:0005634, GO:0005622, GO:0043565, GO:0016986

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1347

Tuberculist Genomic Region

MMP0020 conserved hypothetical protein (NCBI)

Details for MMP0020 - conserved hypothetical protein (NCBI)

GO Terms: GO:0006355, GO:0003677

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0020

Tuberculist Genomic Region

MMP1439 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1 (NCBI)

Details for MMP1439 - 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1 (NCBI)

GO Terms: GO:0046872, GO:0046538, GO:0046537

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1439

Tuberculist Genomic Region

MMP0123 Phosphoribosylglycinamide formyltransferase 2 (NCBI)

Details for MMP0123 - Phosphoribosylglycinamide formyltransferase 2 (NCBI)

GO Terms: GO:0009113, GO:0005524, GO:0016742

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0123

Tuberculist Genomic Region

MMP1533 Conserved hypothetical Archael protein (NCBI)

Details for MMP1533 - Conserved hypothetical Archael protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1533

Tuberculist Genomic Region

MMP0624 conserved hypothetical protein (NCBI)

Details for MMP0624 - conserved hypothetical protein (NCBI)

GO Terms: GO:0010181

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0624

Tuberculist Genomic Region

MMP1534 conserved hypothetical protein (NCBI)

Details for MMP1534 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1534

Tuberculist Genomic Region

MMP0683 signal recognition particle receptor SRalpha (NCBI)

Details for MMP0683 - signal recognition particle receptor SRalpha (NCBI)

GO Terms: GO:0006614, GO:0016020, GO:0048500, GO:0017111, GO:0008312, GO:0005525

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0683

Tuberculist Genomic Region

MMP1642 ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain (NCBI)

Details for MMP1642 - ATP/GTP-binding site motif A (P-loop):Small GTP-binding protein domain (NCBI)

GO Terms: GO:0015684, GO:0005622, GO:0016021, GO:0009276, GO:0005525, GO:0015093

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1642

Tuberculist Genomic Region

MMP0763 hypothetical protein (NCBI)

Details for MMP0763 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0763

Tuberculist Genomic Region

MMP0628 probable Molybdenum-pterin binding protein (NCBI)

Details for MMP0628 - probable Molybdenum-pterin binding protein (NCBI)

GO Terms: GO:0006810, GO:0043190, GO:0005524, GO:0015412, GO:0030151

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0628

Tuberculist Genomic Region

MMP0772 hypothetical protein (NCBI)

Details for MMP0772 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0772

Tuberculist Genomic Region

MMP1154 heterosulfide reductase, subunit C1 (NCBI)

Details for MMP1154 - heterosulfide reductase, subunit C1 (NCBI)

GO Terms: GO:0006118, GO:0051912, GO:0051536, GO:0009055

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1154

Tuberculist Genomic Region

MMP0825 heterodisulfide reductase subunit A (NCBI)

Details for MMP0825 - heterodisulfide reductase subunit A (NCBI)

GO Terms: GO:0006118, GO:0051912, GO:0009055, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0825

Tuberculist Genomic Region

MMP1158 conserved hypothetical protein (NCBI)

Details for MMP1158 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1158

Tuberculist Genomic Region

MMP0908 CBS domain (NCBI)

Details for MMP0908 - CBS domain (NCBI)

GO Terms: GO:0008152, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0908

Tuberculist Genomic Region

MMP1697 heterodisulfide reductase, subunit A (NCBI)

Details for MMP1697 - heterodisulfide reductase, subunit A (NCBI)

GO Terms: GO:0006118, GO:0051912, GO:0009055, GO:0050660, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1697

Tuberculist Genomic Region

MMP1016 Conserved Hypothetical protein with 4 CBS domains. (NCBI)

Details for MMP1016 - Conserved Hypothetical protein with 4 CBS domains. (NCBI)

GO Terms: GO:0008152, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1016

Tuberculist Genomic Region

MMP1156 conserved hypothetical protein (NCBI)

Details for MMP1156 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1156

Tuberculist Genomic Region

MMP1067 Succinate dehydrogenase/fumarate reductase iron-sulfur subunit // Methanosarcina type heterodisulfide reductase subunit D (NCBI)

Details for MMP1067 - Succinate dehydrogenase/fumarate reductase iron-sulfur subunit // Methanosarcina type heterodisulfide reductase subunit D (NCBI)

GO Terms: GO:0006118, GO:0006099, GO:0009055, GO:0000104, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1067

Tuberculist Genomic Region

MMP1660 conserved hypothetical archeal protein (NCBI)

Details for MMP1660 - conserved hypothetical archeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1660

Tuberculist Genomic Region

MMP1134 type A flavoprotein (NCBI)

Details for MMP1134 - type A flavoprotein (NCBI)

GO Terms: GO:0010181, GO:0016491, GO:0016787

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1134

Tuberculist Genomic Region

Displaying 1 - 31 of 31

Motifs

Motif 1: e-value: 1500 e-value: 4600

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)

MMP0480

conserved hypothetical protein (NCBI)
 up-regulates 0.51

MMP0052

MMP0480

H2

 down-regulates -0.29

H2

MMP0097

Transcriptional regulator protein, Helix-turn-helix motif (NCBI)

MMP0527

conserved hypothetical archaeal protein (NCBI)
 up-regulates 0.28

MMP0097

MMP0527

GO Enrichment

Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0010181 FMN binding 10 0.19 3 0.0007
MF GO:0050662 coenzyme binding 28 0.54 3 0.0145
MF GO:0048037 cofactor binding 32 0.62 3 0.0209
MF GO:0051536 iron-sulfur cluster binding 67 1.30 4 0.0339
MF GO:0051540 metal cluster binding 67 1.30 4 0.0339
MF GO:0005488 binding 431 8.36 12 0.0464

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