Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 11 - 20 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

Title	Gene Count	Motif 1 e-value	Motif 2 e-value	Residual	TF Influences
Module_383	9 CD630_32690 - Type: Gene Product:Putative oligoendopeptidase F, M3B family \| Pathway: \| COG: Amino acid transport and metabolism CD630_31560 - Type: Gene Product:phage integrase \| Pathway: \| COG: Replication, recombination and repair CD630_19902 - cspC Type: Gene Product:Major cold shock protein CspC \| Pathway: \| COG: Transcription CD630_13950 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_32700 - Type: Gene Product:Putative magnesium transport ATPase, MgtC/SapBfamily \| Pathway: \| COG: Function unknown CD630_18080 - Type: Gene Product:Pyridoxal-dependent decarboxylase, group IVdecarboxylase family \| Pathway: \| COG: Amino acid transport and metabolism CD630_23100 - cspD Type: Gene Product:Cold shock protein D \| Pathway: \| COG: Transcription CD630_18070 - Type: Gene Product:Putative NADPH-dependent FMN reductase \| Pathway: \| COG: Function unknown CD630_12341 - Type: Gene Product:Putative phage protein \| Pathway: \| COG:	`NA`	`NA`	0.65	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_05590 - Type: Gene Product:Transcriptional regulator, ArsR family \| Pathway: \| COG: Transcription CD630_19100 - eutV Type: Gene Product:Two-component response regulator, Ethanolaminespecific \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_337	26 CD630_13781 - Type: Gene Product:Transcriptional regulator, Phage-type \| Pathway: \| COG: Function unknown CD630_35860 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_13782 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_08850 - glgP Type: Gene Product:Glycogen phosphorylase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_21460 - Type: Gene Product:Conserved hypothetical protein, UPF0027 family \| Pathway: \| COG: Replication, recombination and repair CD630_32890 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_32870 - Type: Gene Product:Putative oxidoreductase, FAD dependent \| Pathway: \| COG: Function unknown CD630_08120 - Type: Gene Product:Putative universal stress protein A (UspA) \| Pathway: \| COG: Signal transduction mechanisms CD630_22550 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_09040 - Type: Gene Product:Putative phage integrase \| Pathway: \| COG: Replication, recombination and repair CD630_22890 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_08840 - glgA Type: Gene Product:Glycogen synthase (Starch [bacterial glycogen]synthase) \| Pathway: Glycan biosynthesis \| COG: Carbohydrate transport and metabolism CD630_08820 - glgC Type: Gene Product:Glucose-1-phosphate adenylyltransferase \| Pathway: Glycan biosynthesis \| COG: Carbohydrate transport and metabolism CD630_07020 - Type: Gene Product:Putative membrane protein, DUF1275 family \| Pathway: \| COG: Function unknown CD630_08860 - Type: Gene Product:Putative alpha-amylase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_35870 - Type: Gene Product:Two-component response regulator, CheY family \| Pathway: \| COG: Signal transduction mechanisms CD630_35850 - Type: Gene Product:ABC-type transport system, ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_22880 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_32880 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_32860 - Type: Gene Product:Putative sodium:phosphate symporter \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_32900 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_32840 - HtrA Type: Gene Product:High temperature requirement A protease \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_08130 - Type: Gene Product:Putative PTS system, IIB component \| Pathway: \| COG: CD630_15790 - Type: Gene Product:Two-component sensor histidine kinase,sporulation-associated spo0A \| Pathway: \| COG: Signal transduction mechanisms CD630_35840 - Type: Gene Product:ABC-type transport system, permease \| Pathway: \| COG: Defense mechanisms CD630_08830 - glgD Type: Gene Product:Glycogen biosynthesis protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis	0.000000000008	`NA`	0.65	Inferelator: 5 Hypergeometric: 1 TF Influences from Inferelator CD630_06700 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription CD630_20480 - Type: Gene Product:Transcriptional regulator, RpiR family \| Pathway: \| COG: Transcription CD630_22140 - SinR Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_23900 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription CD630_35440 - Type: Gene Product:Transcriptional regulator, AsnC/Lrp family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test CD630_12750 - codY Type: Gene Product:Transcriptional regulator, GTP-sensingpleiotropic repressor \| Pathway: \| COG: Transcription
Module_207	8 CD630_06750 - Type: Gene Product:Putative acetyltransferase \| Pathway: \| COG: Function unknown CD630_08450 - Type: Gene Product:Putative nuclease \| Pathway: \| COG: Transcription CD630_13430 - glnA Type: Gene Product:Glutamine synthetase \| Pathway: \| COG: Amino acid transport and metabolism CD630_08460 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_21500 - Type: Gene Product:Putative endonuclease/exonuclease/phosphatase \| Pathway: \| COG: Function unknown CD630_24310 - Type: Gene Product:Putative nitrite/sulphite reductase \| Pathway: \| COG: Energy production and conversion CD630_35512 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_06550 - Type: Gene Product:Putative beta-lactamase-like protein \| Pathway: \| COG: Function unknown	`NA`	`NA`	0.65	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_28690 - Type: Gene Product:Transcriptional regulator, sigma-54-dependent \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_327	22 CD630_29470 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_29471 - Type: Gene Product:Hypothetical protein \| Pathway: \| COG: CD630_29430 - Type: Gene Product:Putative phage replication protein \| Pathway: \| COG: Replication, recombination and repair CD630_20120 - hydD Type: Gene Product:Putative hydrolase \| Pathway: \| COG: Function unknown CD630_29450 - Type: Gene Product:Putative bacteriophage resistance protein \| Pathway: \| COG: Function unknown CD630_07810 - Type: Gene Product:Putative penicillin-binding protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_29510 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: Function unknown CD630_14350 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_29490 - Type: Gene Product:Transcriptional regulator, Phage-type \| Pathway: \| COG: Transcription CD630_29460 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_20130 - hydR Type: Gene Product:Transcriptional regulator, TetR family \| Pathway: \| COG: Transcription CD630_29500 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_29440 - Type: Gene Product:Putative phage essential recombination functionprotein \| Pathway: \| COG: Replication, recombination and repair CD630_29520 - Type: Gene Product:Putative phage site-specific integrase \| Pathway: \| COG: Replication, recombination and repair CD630_29420 - Type: Gene Product:Putative phage resolvase/integrase \| Pathway: \| COG: CD630_14360 - Type: Gene Product:Putative hydrolase \| Pathway: \| COG: Defense mechanisms CD630_01540 - hpdC Type: Gene Product:4-hydroxyphenylacetate decarboxylase, regulatorysubunit \| Pathway: \| COG: Function unknown CD630_14340 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_29480 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: Transcription CD630_07820 - Type: Gene Product:Putative sporulation protein YunB \| Pathway: \| COG: Function unknown	0.000023	`NA`	0.65	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_11770 - fapR Type: Gene Product:Transcriptional regulator, DeoR family (Fattyacid and phospholipid biosynthesis regulator) \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_214	23 CD630_t0570 - tRNA-Ser Type: Gene Product: \| Pathway: \| COG: CD630_t0210 - tRNA-Lys Type: Gene Product: \| Pathway: \| COG: CD630_t0600 - tRNA-Trp Type: Gene Product: \| Pathway: \| COG: CD630_t0450 - tRNA-Val Type: Gene Product: \| Pathway: \| COG: CD630_03900 - bglG Type: Gene Product:Transcription antiterminator, PTS operonregulator \| Pathway: \| COG: Transcription CD630_11300 - Type: Gene Product:Putative lytic transglycosylase-like protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_t0720 - tRNA-Met Type: Gene Product: \| Pathway: \| COG: CD630_t0700 - tRNA-Asn Type: Gene Product: \| Pathway: \| COG: CD630_02921 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_03880 - bglF Type: Gene Product:PTS system, beta-glucoside-specific IIABCcomponent \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_08140 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_t0440 - tRNA-Arg Type: Gene Product: \| Pathway: \| COG: CD630_33872 - Type: Gene Product:Fragment of conjugative transposon proteinTn916-like, CTn7-Orf26 (C-terminal region) \| Pathway: \| COG: CD630_t0220 - tRNA-Cys Type: Gene Product: \| Pathway: \| COG: CD630_t0750 - tRNA-Val Type: Gene Product: \| Pathway: \| COG: CD630_11310 - Type: Gene Product:Putative solute-binding lipoprotein \| Pathway: \| COG: Amino acid transport and metabolism CD630_t0560 - tRNA-Lys Type: Gene Product: \| Pathway: \| COG: CD630_22841 - Type: Gene Product:Fragment of putative beta-lactamase inducer(C-terminal region) \| Pathway: \| COG: CD630_08160 - bglF Type: Gene Product:PTS system, beta-glucoside-specific IIABCcomponent (Disrupted IStron) \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_31382 - Type: Gene Product:Fragment of conserved hypothetical protein(Central region) \| Pathway: \| COG: CD630_03890 - bglA Type: Gene Product:6-phospho-beta-glucosidase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_11280 - polA Type: Gene Product:DNA polymerase I (POLI) \| Pathway: \| COG: Replication, recombination and repair CD630_08150 - Type: Gene Product:Transporter, Major Facilitator Superfamily (MFS) \| Pathway: \| COG: Carbohydrate transport and metabolism	0	6.2e-32	0.65	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_25080 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_288	21 CD630_12080 - Type: Gene Product:Putative RNA-binding S4-domain protein \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_12050 - ispA Type: Gene Product:Geranyltranstransferase \| Pathway: \| COG: Coenzyme transport and metabolism CD630_12060 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_24710 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_25560 - Type: Gene Product:PTS system, fructose/mannitol-family IIABcomponent \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_12090 - recN Type: Gene Product:DNA repair protein RecN (Recombination proteinN) \| Pathway: \| COG: Replication, recombination and repair CD630_11960 - spoIIIAE Type: Gene Product:Stage III sporulation protein AE \| Pathway: \| COG: Function unknown CD630_23290 - tal Type: Gene Product:Transaldolase \| Pathway: Carbohydrate degradation \| COG: Carbohydrate transport and metabolism CD630_23170 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_23300 - xpt Type: Gene Product:Xanthine phosphoribosyltransferase (XPRTase) \| Pathway: Purine metabolism \| COG: Nucleotide transport and metabolism CD630_25930 - Type: Gene Product:ABC-type transport system,pristinamycin/multidrug-family ATP-binding protein \| Pathway: \| COG: Function unknown CD630_25550 - Type: Gene Product:PTS system, fructose/mannitol-family IIBcomponent \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_23160 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_12020 - gcp Type: Gene Product:O-sialoglycoprotein endopeptidase, peptidase M22family \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_12070 - dxs Type: Gene Product:1-deoxy-D-xylulose-5-phosphate synthase \| Pathway: Metabolic intermediate biosynthesis \| COG: Coenzyme transport and metabolism CD630_12000 - Type: Gene Product:Conserved hypothetical protein, DUF322 familly \| Pathway: \| COG: Function unknown CD630_06271 - Type: Gene Product:Putative ferredoxin \| Pathway: \| COG: Energy production and conversion CD630_24720 - Type: Gene Product:Transcriptional regulator, ArsR family \| Pathway: \| COG: Function unknown CD630_12030 - xseA Type: Gene Product:Exodeoxyribonuclease 7 large subunit \| Pathway: \| COG: Replication, recombination and repair CD630_06280 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_12010 - nusB Type: Gene Product:N utilization substance protein B homolog(Protein NusB) \| Pathway: \| COG: Transcription	0.05	0.18	0.64	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_06480 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_23900 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_240	21 CD630_18700 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf29 \| Pathway: \| COG: Function unknown CD630_18690 - Type: Gene Product:Putative endonuclease relaxase Tn1549-like,CTn5-Orf28 \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_18711 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf31 \| Pathway: \| COG: CD630_18710 - Type: Gene Product:Putative oxidoreductase Tn1549-like, CTn5-Orf30 \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_32140 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_20010 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_11210 - pflC Type: Gene Product:Pyruvate formate-lyase 2-activating enzyme \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_04330 - Type: Gene Product:ABC-type transport system, multidrug-familypermease Tn1549-like, CTn2-Orf28 \| Pathway: \| COG: Defense mechanisms CD630_01450 - Type: Gene Product:Putative resolvase, S1 RNA-bindingdomain-containing protein \| Pathway: \| COG: Transcription CD630_18770 - vncS Type: Gene Product:Two-component sensor histidine kinase;Tn1549-like, CTn5-Orf37 \| Pathway: \| COG: Signal transduction mechanisms CD630_18740 - vexP2 Type: Gene Product:ABC-type transport system, ATP-binding proteinTn1549-like, CTn5-Orf34 \| Pathway: \| COG: Defense mechanisms CD630_11220 - Type: Gene Product:Transcriptional regulator, RmlC-type \| Pathway: \| COG: Transcription CD630_11200 - pflD Type: Gene Product:Formate acetyltransferase (Pyruvateformate-lyase) \| Pathway: \| COG: Energy production and conversion CD630_18760 - vncR Type: Gene Product:Two-component response regulator; Tn1549-like,CTn5-Orf36 \| Pathway: \| COG: Signal transduction mechanisms CD630_01460 - Type: Gene Product:Putative hydrolase \| Pathway: \| COG: Secondary metabolites biosynthesis, transport and catabolism CD630_04270 - Type: Gene Product:Transcriptional regulator, HTH-type Tn1549-like,CTn2-Orf22 \| Pathway: \| COG: Transcription CD630_18720 - Type: Gene Product:Putative iron-sulfur binding protein Tn1549-like,CTn5-Orf32 \| Pathway: \| COG: Energy production and conversion CD630_18730 - vexP1 Type: Gene Product:ABC-type transport system, permease Tn1549-like,CTn5-Orf33 \| Pathway: \| COG: Defense mechanisms CD630_04280 - Type: Gene Product:Transcriptional regulator, AraC familyTn1549-like, CTn2-Orf23 \| Pathway: \| COG: Transcription CD630_20020 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_18750 - vexP3 Type: Gene Product:ABC-type transport system, permease Tn1549-like,CTn5-Orf35 \| Pathway: \| COG: Defense mechanisms	0.01	0.82	0.64	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_18860 - Type: Gene Product:Transcriptional regulator, PadR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_331	21 CD630_16250 - vanS Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_02740 - Type: Gene Product:Putative iron-containing alcohol dehydrogenase \| Pathway: \| COG: Energy production and conversion CD630_06460 - Type: Gene Product:ABC-type transport system,lantibiotic/multidrug-family permease \| Pathway: \| COG: Function unknown CD630_16240 - vanR Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_08300 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_33250 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Energy production and conversion CD630_06440 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_22730 - Type: Gene Product:Putative sporulation integral membrane protein \| Pathway: \| COG: Function unknown CD630_r0080 - 23s_rRNA Type: Gene Product: \| Pathway: \| COG: CD630_29660 - adhE Type: Gene Product:Aldehyde-alcohol dehydrogenase \| Pathway: \| COG: Energy production and conversion CD630_30060 - Type: Gene Product:Alcohol dehydrogenase \| Pathway: \| COG: Energy production and conversion CD630_19580 - Type: Gene Product:Putative 4Fe-4S binding protein; putativeferredoxin; putative dehydrogenase; putative reductase \| Pathway: \| COG: Energy production and conversion CD630_08940 - Type: Gene Product:Putative iron-dependent hydrogenase \| Pathway: \| COG: Energy production and conversion CD630_16670 - Type: Gene Product:Putative maltose O-acetyltransferase \| Pathway: \| COG: Amino acid transport and metabolism CD630_23760 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_06430 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_07400 - Type: Gene Product:Putative pyridoxal phosphate-dependentaminotransferase \| Pathway: \| COG: Amino acid transport and metabolism CD630_16540 - Type: Gene Product:Putative lipoate-protein ligase \| Pathway: Protein modification \| COG: Coenzyme transport and metabolism CD630_00300 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_32500 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_20171 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG:	0.0000000013	`NA`	0.64	Inferelator: 2 Hypergeometric: 1 TF Influences from Inferelator CD630_16240 - vanR Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_17980 - Type: Gene Product:Transcriptional regulator, LysR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test CD630_32450 - prdR Type: Gene Product:Transcriptional regulator, sigma-54-dependent \| Pathway: \| COG: Transcription
Module_99	26 CD630_05940 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_10230 - Type: Gene Product:Putative transcriptional regulator, HTH \| Pathway: \| COG: Transcription CD630_23850 - Type: Gene Product:Putative diguanylate cyclase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_17520 - Type: Gene Product:Transcriptional regulator, TetR family \| Pathway: \| COG: Transcription CD630_23860 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_17560 - def1 Type: Gene Product:Peptide deformylase 1 (PDF 1) (Polypeptidedeformylase 1) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_17570 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_17540 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_25190 - Type: Gene Product:Integrase \| Pathway: \| COG: Replication, recombination and repair CD630_10240 - potA Type: Gene Product:ABC-type transport system, spermidine/putrescineATP-binding protein \| Pathway: \| COG: Amino acid transport and metabolism CD630_22280 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_23770 - Type: Gene Product:Putative hydrolase, NUDIX family \| Pathway: \| COG: Replication, recombination and repair CD630_23840 - Type: Gene Product:Putative diguanylate cyclase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_10260 - potC Type: Gene Product:ABC-type transport system, spermidine/putrescinepermease \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_05950 - Type: Gene Product:Putative nuclease, ParB-like \| Pathway: \| COG: Transcription CD630_17530 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_28420 - Type: Gene Product:Nitrilase (carbon-nitrogen hydrolase) \| Pathway: \| COG: Function unknown CD630_23830 - Type: Gene Product:Transcriptional regulator, sigma-54-dependent \| Pathway: \| COG: Transcription CD630_23780 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_17550 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_17551 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_22270 - Type: Gene Product:Putative radical SAM superfamily lipoprotein \| Pathway: \| COG: Energy production and conversion CD630_25180 - cwp29 Type: Gene Product:Cell surface protein \| Pathway: \| COG: Function unknown CD630_10250 - potB Type: Gene Product:ABC-type transport system, spermidine/putrescinepermease \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_10270 - potD Type: Gene Product:ABC-type transport system, spermidine/putrescinesolute-binding protein \| Pathway: \| COG: Amino acid transport and metabolism CD630_17580 - Type: Gene Product:Putative radical SAM superfamily protein \| Pathway: \| COG: Replication, recombination and repair	0.01	0.56	0.64	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_23830 - Type: Gene Product:Transcriptional regulator, sigma-54-dependent \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_334	6 CD630_06740 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_09780 - Type: Gene Product:Transcriptional regulator, beta-lactams repressorPhage-type \| Pathway: \| COG: CD630_18441 - Type: Gene Product:Fragment of putative methyltransferase(N-terminal region) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_17591 - Type: Gene Product:Fragment of conserved hypothetical protein,UPF0027 family (C-terminal region) \| Pathway: \| COG: CD630_01960 - Type: Gene Product:Fragment of conserved hypothetical protein,DUF111 family (Part 1) \| Pathway: \| COG: Function unknown, Function unknown	`NA`	`NA`	0.63	Inferelator: 0 Hypergeometric: 0 TF Influences from Inferelator `No TF influences from Inferelator` TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`