MSMEG_6104 MSMEG_6104 GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_6104	MSMEG_6104	folE	folE, MSMEG_6104, MSMEI_5945		GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I)				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0131	0.55
msm_bicluster_0197	0.52

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0R587	4537026;	WP_011731040.1, YP_890325.1	ABK75591, AFP42378, AIU11101	IPR001474, IPR018234, IPR020602	COG0302, ENOG4105EUJ	EOG6XHC8G

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
GTP + H(2)O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate, ECO:0000256|HAMAP-Rule:MF_00223, ECO:0000256|SAAS:SAAS00348637}.	msb:LJ00_30185, msg:MSMEI_5945, msm:MSMEG_6104	Cofactor biosynthesis, 7,8-dihydroneopterin triphosphate biosynthesis, 7,8-dihydroneopterin triphosphate from GTP: step 1/1. {ECO:0000256|HAMAP-Rule:MF_00223, ECO:0000256|SAAS:SAAS00348631}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0035998 GO:0005525 GO:0003934 GO:0005737 GO:0006730 GO:0046654 GO:0008270 -

GO:0035998

GO:0005525

GO:0003934

GO:0005737

GO:0006730

GO:0046654

GO:0008270

String Network

Link to STRINGS	STRINGS Network
MSMEG_6104

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