25707 P4Hc
Thalassiosira pseudonana

Genome Browser

Summary

Chromosome Product Transcript Start End Strand Short Name
25707 chr_22 P4Hc 347918 352320 + P4Hc

Synonyms

Hierarchical Clustering

Expression Profile Conditional Changes Cluster Dendrogram
Thaps_hclust_0031

Motif-Guided Biclusters

Normalized Mean Residue
Thaps_bicluster_0081
 0.42

Most Highly Correlated Transcripts

bd783

(bd783) Rieske superfamily
0.8843

bd1645

(bd1645) tpt
0.8758

bd1893

(bd1893) NA
0.8746

bd790

(bd790) ABCC_MRP_domain2
0.8551

bd298

(bd298) ABM superfamily
0.8548

bd1350

(bd1350) psaF
0.8496

bd1765

(bd1765) NA
0.8428

bd1161

(bd1161) NA
0.8376

bd463

(bd463) Aa_trans superfamily
0.8258

bd1380

(bd1380) ycf39
0.8252

Conserved Domains

Name CD Accession Definition Superfamily Bitscore E-Value From - To Hit Type PSSM ID
P4Hc Prolyl 4-hydroxylase alpha subunit homologues; Mammalian enzymes catalyse hydroxylation of collagen... cl17304 86.2878 5.35E-19 947 - 1117 specific 214780
2OG-FeII_Oxy_3 superfamily 2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and Fe(... - 86.2878 5.35E-19 947 - 1117 superfamily 266616

Homologs in Other Species

T. pseudonana P. tricornutum P. tricornutum DiatomCyc F. cylindrus Pseudo-nitzschia multiseries E. huxleyi C. reinhardtii A. thaliana P. sojae
Not available Not available 234605 Not available Not available Not available Not available Not available

KEGG

KEGG description KEGG Pathway
Not available Not available

GO Terms

GO:0016706 GO:0019538 GO:0004656 GO:0016222 -

GO:0016706

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

Details: 
Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.
GO Category: 
MF

GO:0019538

protein metabolic process

Details: 
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO Category: 
BP

GO:0004656

procollagen-proline 4-dioxygenase activity

Details: 
Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
GO Category: 
MF

GO:0016222

procollagen-proline 4-dioxygenase complex

Details: 
A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase.
GO Category: 
CC

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