GO:0004435

phosphatidylinositol phospholipase C activity

Details: 
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).
GO Category: 
MF
PI-PLCc_eukaryota
PI-PLCc_eukaryota
PI-PLCc_GDPD_SF superfamily
C2_PLC_like