alkylbase DNA N-glycosylase activity
name: alkylbase DNA N-glycosylase activity
Description: Catalysis of the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine. Enzymes with this activity recognize and remove alkylated purines and pyrimidines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic or apyrimidinic (AP) site.
|GO:0008725||DNA-3-methyladenine glycosylase I activity|
|GO:0043733||DNA-3-methyladenine glycosylase III activity|
|GO:0043736||DNA-3-methyladenine glycosylase IV activity|
|GO:0043916||DNA-7-methylguanine glycosylase activity|
|GO:0019104||DNA N-glycosylase activity|