Signal transduction mechanisms

id: T
name: Signal transduction mechanisms
namespace: cog subcategory
type: cog
obsolete: False

Child Functions

COG0271Stress-induced morphogen (activity unknown)
COG0317Guanosine polyphosphate pyrophosphohydrolases/synthetases
COG0467RecA-superfamily ATPases implicated in signal transduction
COG0478RIO-like serine/threonine protein kinase fused to N-terminal HTH domain
COG0515Serine/threonine protein kinase
COG0589Universal stress protein UspA and related nucleotide-binding proteins
COG0631Serine/threonine protein phosphatase
COG0639Diadenosine tetraphosphatase and related serine/threonine protein phosphatases
COG0642Signal transduction histidine kinase
COG0643Chemotaxis protein histidine kinase and related kinases
COG0664cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
COG0745Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COG0784FOG: CheY-like receiver
COG0834ABC-type amino acid transport/signal transduction systems, periplasmic component/domain
COG0835Chemotaxis signal transduction protein
COG0840Methyl-accepting chemotaxis protein
COG1217Predicted membrane GTPase involved in stress response
COG1221Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
COG1352Methylase of chemotaxis methyl-accepting proteins
COG1366Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
COG1391Glutamine synthetase adenylyltransferase
COG1493Serine kinase of the HPr protein, regulates carbohydrate metabolism
COG1551Carbon storage regulator (could also regulate swarming and quorum sensing)
COG1639Predicted signal transduction protein
COG1702Phosphate starvation-inducible protein PhoH, predicted ATPase
COG1716FOG: FHA domain
COG1718Serine/threonine protein kinase involved in cell cycle control
COG1734DnaK suppressor protein
COG1762Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)
COG1776Chemotaxis protein CheC, inhibitor of MCP methylation
COG1842Phage shock protein A (IM30), suppresses sigma54-dependent transcription
COG1854LuxS protein involved in autoinducer AI2 synthesis
COG1871Chemotaxis protein; stimulates methylation of MCP proteins
COG1875Predicted ATPase related to phosphate starvation-inducible protein PhoH
COG1956GAF domain-containing protein
COG1966Carbon starvation protein, predicted membrane protein
COG1974SOS-response transcriptional repressors (RecA-mediated autopeptidases)
COG1983Putative stress-responsive transcriptional regulator
COG2062Phosphohistidine phosphatase SixA
COG2112Predicted Ser/Thr protein kinase
COG2114Adenylate cyclase, family 3 (some proteins contain HAMP domain)
COG2172Anti-sigma regulatory factor (Ser/Thr protein kinase)
COG2197Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COG2198FOG: HPt domain
COG2199FOG: GGDEF domain
COG2200FOG: EAL domain
COG2201Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain
COG2202FOG: PAS/PAC domain
COG2203FOG: GAF domain
COG2204Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
COG2205Osmosensitive K+ channel histidine kinase
COG2206HD-GYP domain
COG2208Serine phosphatase RsbU, regulator of sigma subunit
COG2310Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1
COG2336Growth regulator
COG2337Growth inhibitor
COG2365Protein tyrosine/serine phosphatase
COG2453Predicted protein-tyrosine phosphatase
COG2508Regulator of polyketide synthase expression
COG2766Putative Ser protein kinase
COG2770FOG: HAMP domain
COG2905Predicted signal-transduction protein containing cAMP-binding and CBS domains
COG2972Predicted signal transduction protein with a C-terminal ATPase domain
COG3026Negative regulator of sigma E activity
COG3073Negative regulator of sigma E activity
COG3086Positive regulator of sigma E activity
COG3103SH3 domain protein
COG3109Activator of osmoprotectant transporter ProP
COG3143Chemotaxis protein
COG3275Putative regulator of cell autolysis
COG3279Response regulator of the LytR/AlgR family
COG3290Signal transduction histidine kinase regulating citrate/malate metabolism
COG3292Predicted periplasmic ligand-binding sensor domain
COG3300MHYT domain (predicted integral membrane sensor domain)
COG3322Predicted periplasmic ligand-binding sensor domain
COG3434Predicted signal transduction protein containing EAL and modified HD-GYP domains
COG3437Response regulator containing a CheY-like receiver domain and an HD-GYP domain
COG3447Predicted integral membrane sensor domain
COG3448CBS-domain-containing membrane protein
COG3452Predicted periplasmic ligand-binding sensor domain
COG3456Uncharacterized conserved protein, contains FHA domain
COG3476Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
COG3480Predicted secreted protein containing a PDZ domain
COG3604Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains
COG3605Signal transduction protein containing GAF and PtsI domains
COG3614Predicted periplasmic ligand-binding sensor domain
COG3629DNA-binding transcriptional activator of the SARP family
COG3642Mn2+-dependent serine/threonine protein kinase
COG3678P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein
COG3706Response regulator containing a CheY-like receiver domain and a GGDEF domain
COG3707Response regulator with putative antiterminator output domain
COG3712Fe2+-dicitrate sensor, membrane component
COG3806Anti-sigma factor
COG3829Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
COG3830ACT domain-containing protein
COG3835Sugar diacid utilization regulator
COG3848Phosphohistidine swiveling domain
COG3850Signal transduction histidine kinase, nitrate/nitrite-specific
COG3851Signal transduction histidine kinase, glucose-6-phosphate specific
COG3852Signal transduction histidine kinase, nitrogen specific
COG3887Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain
COG3916N-acyl-L-homoserine lactone synthetase
COG3920Signal transduction histidine kinase
COG3947Response regulator containing CheY-like receiver and SARP domains
COG4191Signal transduction histidine kinase regulating C4-dicarboxylate transport system
COG4192Signal transduction histidine kinase regulating phosphoglycerate transport system
COG4219Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component
COG4250Predicted sensor protein/domain
COG4251Bacteriophytochrome (light-regulated signal transduction histidine kinase)
COG4252Predicted transmembrane sensor domain
COG4512Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide
COG4564Signal transduction histidine kinase
COG4565Response regulator of citrate/malate metabolism
COG4566Response regulator
COG4567Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
COG4579Isocitrate dehydrogenase kinase/phosphatase
COG4585Signal transduction histidine kinase
COG4650Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain
COG4725Transcriptional activator, adenine-specific DNA methyltransferase
COG4753Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
COG4862Negative regulator of genetic competence, sporulation and motility
COG4936Predicted sensor domain
COG4943Predicted signal transduction protein containing sensor and EAL domains
COG4978Transcriptional regulator, effector-binding domain/component
COG4999Uncharacterized domain of BarA-like signal transduction histidine kinases
COG5000Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation
COG5001Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain
COG5002Signal transduction histidine kinase
COG5032Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family
COG5035Cell cycle control protein
COG5037Gluconate transport-inducing protein
COG504014-3-3 family protein
COG5041Casein kinase II, beta subunit
COG5057Phosphotyrosyl phosphatase activator
COG5126Ca2+-binding protein (EF-Hand superfamily)
COG5130Prenylated rab acceptor 1 and related proteins
COG5170Serine/threonine protein phosphatase 2A, regulatory subunit
COG5212Low-affinity cAMP phosphodiesterase
COG5238Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport
COG5253Phosphatidylinositol-4-phosphate 5-kinase
COG5261Protein involved in regulation of cellular morphogenesis/cytokinesis
COG5278Predicted periplasmic ligand-binding sensor domain
COG5329Phosphoinositide polyphosphatase (Sac family)
COG5408SPX domain-containing protein
COG5409EXS domain-containing protein
COG5411Phosphatidylinositol 5-phosphate phosphatase
COG5422RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
COG5432RING-finger-containing E3 ubiquitin ligase
COG5585NAD+--asparagine ADP-ribosyltransferase
COG5599Protein tyrosine phosphatase
COG5635Predicted NTPase (NACHT family)

Parent Functions

35631Cellular processes and signaling