nucleotide-excision repair

id: GO:0006289
name: nucleotide-excision repair
namespace: biological_process
type: go
obsolete: False

Description: A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).

Child Functions

GO:0000720pyrimidine dimer repair by nucleotide-excision repair
GO:0006283transcription-coupled nucleotide-excision repair
GO:0070911global genome nucleotide-excision repair

Parent Functions

GO:0006281DNA repair