GPI anchor biosynthetic process

id: GO:0006506
name: GPI anchor biosynthetic process
namespace: biological_process
type: go
obsolete: False

Description: The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.

Child Functions

GO:0018265GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine
GO:0018266GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine
GO:0018267GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine
GO:0018268GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine
GO:0018269GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine
GO:0018270GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine
GO:0050493GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine

Parent Functions

GO:0006497protein lipidation
GO:0006505GPI anchor metabolic process
GO:0006661phosphatidylinositol biosynthetic process