heparan sulfate proteoglycan biosynthetic process

id: GO:0015012
name: heparan sulfate proteoglycan biosynthetic process
namespace: biological_process
type: go
obsolete: False

Description: The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.

Parent Functions

GO:0030166proteoglycan biosynthetic process
GO:0030201heparan sulfate proteoglycan metabolic process
GO:0044272sulfur compound biosynthetic process