heparan sulfate proteoglycan biosynthetic process
name: heparan sulfate proteoglycan biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.
|GO:0030166||proteoglycan biosynthetic process|
|GO:0030201||heparan sulfate proteoglycan metabolic process|
|GO:0044272||sulfur compound biosynthetic process|