mitotic checkpoint complex

id: GO:0033597
name: mitotic checkpoint complex
namespace: cellular_component
type: go
obsolete: False

Description: A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.

Parent Functions

GO:0043234protein complex
GO:0044428nuclear part