protein targeting to ER
name: protein targeting to ER
Description: The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
|GO:0006614||SRP-dependent cotranslational protein targeting to membrane|
|GO:0006620||posttranslational protein targeting to membrane|
|GO:0072599||establishment of protein localization in endoplasmic reticulum|