protein targeting to ER

id: GO:0045047
name: protein targeting to ER
namespace: biological_process
type: go
obsolete: False

Description: The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.

Child Functions

GO:0006614SRP-dependent cotranslational protein targeting to membrane
GO:0006620posttranslational protein targeting to membrane

Parent Functions

GO:0006605protein targeting
GO:0072599establishment of protein localization in endoplasmic reticulum