synapse

id: GO:0045202
name: synapse
namespace: cellular_component
type: go
obsolete: False

Description: The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.

Child Functions

idname
GO:0031594neuromuscular junction
GO:0032279asymmetric synapse
GO:0032280symmetric synapse
GO:0060076excitatory synapse
GO:0060077inhibitory synapse

Parent Functions

idname
GO:0005575cellular_component