BRCA1-A complex

id: GO:0070531
name: BRCA1-A complex
namespace: cellular_component
type: go
obsolete: False

Description: A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.

Parent Functions

GO:0043234protein complex
GO:0044428nuclear part