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- spindle pole
- gamma-tubulin complex
- DNA binding
- antigen binding
- ubiquitin-protein ligase activity
- protein binding
- nucleus
- centriole
- ubiquitin-dependent protein catabolic process
- protein monoubiquitination
- cellular response to DNA damage stimulus
- zinc ion binding
- intrinsic apoptotic signaling pathway in response to DNA damage
- PML body
- nuclear speck
- ligase activity
- protein sumoylation
- SUMO ligase activity
- photoreceptor connecting cilium
- protein localization to nucleus
- ciliary basal body
- regulation of cell proliferation
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
- proteasome-mediated ubiquitin-dependent protein catabolic process
- DNA topoisomerase binding
- positive regulation of transcription, DNA-templated
- metal ion binding
- positive regulation of ubiquitin-protein ligase activity
- maintenance of protein location in nucleus
- protein K48-linked ubiquitination
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