Ptpn6 protein tyrosine phosphatase, non-receptor type 6 (15170)

Symbol Product Feature Type Strand Chr
15170 Ptpn6 protein tyrosine phosphatase, non-receptor type 6 protein-coding 6
Synonyms
70Z-SHP | Hcph | PTPTY-42 | Ptp1C | SH-PTP1 | SHP-1 | hcp | me
GO ID Category Definition Evidence
  • phosphotyrosine binding
  • negative regulation of humoral immune response mediated by circulating immunoglobulin
  • phosphoprotein phosphatase activity
  • protein tyrosine phosphatase activity
  • transmembrane receptor protein tyrosine phosphatase activity
  • protein binding
  • intracellular
  • nucleus
  • cytoplasm
  • protein dephosphorylation
  • signal transduction
  • cell proliferation
  • positive regulation of cell proliferation
  • positive regulation of phosphatidylinositol 3-kinase signaling
  • dephosphorylation
  • hydrolase activity
  • phosphatase activity
  • SH3 domain binding
  • peptidyl-tyrosine phosphorylation
  • cytokine-mediated signaling pathway
  • protein kinase binding
  • cell differentiation
  • platelet formation
  • abortive mitotic cell cycle
  • positive regulation of cell adhesion mediated by integrin
  • peptidyl-tyrosine dephosphorylation
  • intracellular signal transduction
  • megakaryocyte development
  • alpha-beta T cell receptor complex
  • negative regulation of T cell proliferation
  • SH2 domain binding
  • natural killer cell mediated cytotoxicity
  • negative regulation of MAP kinase activity
  • negative regulation of MAPK cascade
  • regulation of B cell differentiation
  • natural killer cell lectin-like receptor binding
  • negative regulation of peptidyl-tyrosine phosphorylation
  • B cell receptor signaling pathway
  • negative regulation of B cell receptor signaling pathway
  • negative regulation of T cell receptor signaling pathway
  • regulation of release of sequestered calcium ion into cytosol
  • regulation of ERK1 and ERK2 cascade
  • platelet aggregation
  • regulation of G1/S transition of mitotic cell cycle
Motif 1 Motif 2 Residual
PITA_153 |
Residual: 
0.91
0.91
PITA_165 |
Residual: 
0.26
0.26
TargetScan_114 |
Residual: 
0.26
0.26
TargetScan_180 |
Residual: 
0.73
0.73
Displaying 1 - 4 of 4
Entrez ID STRINGS Network
STRING
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