Tlr4 toll-like receptor 4 (21898)

Symbol Product Feature Type Strand Chr
21898 Tlr4 toll-like receptor 4 protein-coding 4
Synonyms
Lps | Ly87 | Ran/M1 | Rasl2-8
GO ID Category Definition Evidence
  • activation of MAPK activity
  • lipopolysaccharide binding
  • microglial cell activation
  • lipopolysaccharide receptor activity
  • activation of innate immune response
  • toll-like receptor signaling pathway
  • B cell proliferation involved in immune response
  • immune system process
  • nitric oxide production involved in inflammatory response
  • MyD88-dependent toll-like receptor signaling pathway
  • innate immune response-activating signal transduction
  • receptor activity
  • transmembrane signaling receptor activity
  • protein binding
  • cytoplasm
  • plasma membrane
  • integral component of plasma membrane
  • leukotriene metabolic process
  • inflammatory response
  • immune response
  • response to oxidative stress
  • signal transduction
  • activation of NF-kappaB-inducing kinase activity
  • I-kappaB phosphorylation
  • response to bacterium
  • external side of plasma membrane
  • cell surface
  • positive regulation of platelet activation
  • membrane
  • integral component of membrane
  • positive regulation of B cell proliferation
  • lipopolysaccharide-mediated signaling pathway
  • response to lipopolysaccharide
  • detection of lipopolysaccharide
  • interferon-gamma production
  • negative regulation of interferon-gamma production
  • negative regulation of interleukin-17 production
  • negative regulation of interleukin-23 production
  • negative regulation of interleukin-6 production
  • negative regulation of tumor necrosis factor production
  • positive regulation of chemokine production
  • positive regulation of interferon-alpha production
  • positive regulation of interferon-beta production
  • positive regulation of interferon-gamma production
  • positive regulation of interleukin-1 production
  • positive regulation of interleukin-10 production
  • positive regulation of interleukin-12 production
  • positive regulation of interleukin-6 production
  • positive regulation of interleukin-8 production
  • positive regulation of tumor necrosis factor production
  • positive regulation of stress-activated MAPK cascade
  • toll-like receptor 4 signaling pathway
  • macrophage activation
  • positive regulation of NF-kappaB import into nucleus
  • positive regulation of tumor necrosis factor biosynthetic process
  • positive regulation of apoptotic process
  • positive regulation of I-kappaB kinase/NF-kappaB signaling
  • positive regulation of DNA binding
  • phosphatidylinositol 3-kinase binding
  • positive regulation of interleukin-12 biosynthetic process
  • innate immune response
  • membrane raft
  • positive regulation of MHC class II biosynthetic process
  • positive regulation of interferon-beta biosynthetic process
  • positive regulation of interleukin-1 biosynthetic process
  • positive regulation of interleukin-13 biosynthetic process
  • positive regulation of interleukin-6 biosynthetic process
  • positive regulation of interleukin-8 biosynthetic process
  • positive regulation of nitric oxide biosynthetic process
  • response to ethanol
  • mast cell activation
  • positive regulation of transcription from RNA polymerase II promoter
  • positive regulation of JNK cascade
  • lipopolysaccharide receptor complex
  • perinuclear region of cytoplasm
  • positive regulation of lymphocyte proliferation
  • regulation of cytokine secretion
  • regulation of inflammatory response
  • positive regulation of inflammatory response
  • positive regulation of peptidyl-tyrosine phosphorylation
  • defense response to Gram-negative bacterium
  • positive regulation of sequence-specific DNA binding transcription factor activity
  • positive regulation of NF-kappaB transcription factor activity
  • positive regulation of nitric-oxide synthase biosynthetic process
  • regulation of sensory perception of pain
  • intestinal epithelial structure maintenance
  • positive regulation of macrophage cytokine production
  • negative regulation of ERK1 and ERK2 cascade
  • positive regulation of ERK1 and ERK2 cascade
  • positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
  • positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
  • response to fatty acid
  • cellular response to lipopolysaccharide
  • cellular response to lipoteichoic acid
Motif 1 Motif 2 Residual
PITA_88 |
Residual: 
0.26
0.26
PITA_90 |
Residual: 
0.22
0.22
TargetScan_76 |
Residual: 
0.19
0.19
TargetScan_81 |
Residual: 
0.23
0.23
Displaying 1 - 4 of 4
Entrez ID STRINGS Network
STRING
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