Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2 (76089) | Macrophage Network Portal

Summary

	Symbol	Product	Feature Type	Strand	Chr
76089	Rapgef2	Rap guanine nucleotide exchange factor (GEF) 2	protein-coding		3

Synonyms

Synonyms
5830453M24Rik \| CNRasGEF \| Pdzgef1 \| RA-GEF-1 \| mKIAA0313 \| nRapGEP

DB XRef

Ensembl	MGI	VEGA
ENSMUSG00000062232	MGI:2659071	OTTMUSG00000031912

GO Terms

GO ID	Category	Definition	Evidence
GO:0001568 GO:0001764 GO:0005085 GO:0005088 GO:0005096 GO:0005622 GO:0005737 GO:0005768 GO:0005770 GO:0005886 GO:0007165 GO:0007186 GO:0007218 GO:0007264 GO:0007275 GO:0007399 GO:0008285 GO:0010976 GO:0016020 GO:0017034 GO:0019901 GO:0019933 GO:0021591 GO:0021884 GO:0030054 GO:0030154 GO:0030165 GO:0031175 GO:0031547 GO:0031697 GO:0032092 GO:0032320 GO:0032486 GO:0032854 GO:0038180 GO:0043005 GO:0043025 GO:0043234 GO:0043950 GO:0045202 GO:0045860 GO:0046582 GO:0048022 GO:0048167 GO:0048471 GO:0050699 GO:0050774 GO:0051056 GO:0061028 GO:0070374 GO:0071320 GO:0071321 GO:0071880 GO:1901888 GO:1990090 GO:2000481 GO:2000670 GO:2001214 GO:2001224	Process Function Component	blood vessel development neuron migration guanyl-nucleotide exchange factor activity Ras guanyl-nucleotide exchange factor activity GTPase activator activity intracellular cytoplasm endosome late endosome plasma membrane signal transduction G-protein coupled receptor signaling pathway neuropeptide signaling pathway small GTPase mediated signal transduction multicellular organismal development nervous system development negative regulation of cell proliferation positive regulation of neuron projection development membrane Rap guanyl-nucleotide exchange factor activity protein kinase binding cAMP-mediated signaling ventricular system development forebrain neuron development cell junction cell differentiation PDZ domain binding neuron projection development brain-derived neurotrophic factor receptor signaling pathway beta-1 adrenergic receptor binding positive regulation of protein binding positive regulation of Ras GTPase activity Rap protein signal transduction positive regulation of Rap GTPase activity nerve growth factor signaling pathway neuron projection neuronal cell body protein complex positive regulation of cAMP-mediated signaling synapse positive regulation of protein kinase activity Rap GTPase activator activity negative regulation of melanin biosynthetic process regulation of synaptic plasticity perinuclear region of cytoplasm WW domain binding negative regulation of dendrite morphogenesis regulation of small GTPase mediated signal transduction establishment of endothelial barrier positive regulation of ERK1 and ERK2 cascade cellular response to cAMP cellular response to cGMP adenylate cyclase-activating adrenergic receptor signaling pathway regulation of cell junction assembly cellular response to nerve growth factor stimulus positive regulation of cAMP-dependent protein kinase activity positive regulation of dendritic cell apoptotic process positive regulation of vasculogenesis positive regulation of neuron migration	IMP IEA ISO IDA

Regulatory Modules

	Motif 1	Motif 2	Residual
PITA_109 \| PITA_109 Residual: 0.23			0.23
PITA_202 \| PITA_202 Residual: 0.26			0.26
PITA_204 \| PITA_204 Residual: 0.11			0.11
TargetScan_11 \| TargetScan_11 Residual: 0.20			0.20
TargetScan_149 \| TargetScan_149 Residual: 0.12			0.12
TargetScan_154 \| TargetScan_154 Residual: 0.23			0.23
TargetScan_192 \| TargetScan_192 Residual: 0.33			0.33
TargetScan_96 \| TargetScan_96 Residual: 0.24			0.24

Regulation

Displaying 1 - 8 of 8

Regulator Locus	Interaction	Weight

String Network

Entrez ID	STRINGS Network
STRING

Add comment

Log in or register to post comments