PITA_134 megaCluster: 8 Residual: 0.13 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_134	8	0.13	15	0	0.969828	0

Members

Displaying 1 - 21 of 21

107029 malic enzyme 2, NAD(+)-dependent, mitochondrial Details for - - malic enzyme 2, NAD(+)-dependent, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107029 Tuberculist Genomic Region	14228 FK506 binding protein 4 Details for - - FK506 binding protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14228 Tuberculist Genomic Region
16558 kinesin family member 16B Details for RP23-442B16.1 - kinesin family member 16B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16558 Tuberculist Genomic Region	17252 retinol dehydrogenase 11 Details for - - retinol dehydrogenase 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17252 Tuberculist Genomic Region
18971 polymerase (DNA directed), delta 1, catalytic subunit Details for - - polymerase (DNA directed), delta 1, catalytic subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18971 Tuberculist Genomic Region	20405 SH3-domain GRB2-like 1 Details for - - SH3-domain GRB2-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20405 Tuberculist Genomic Region
20822 TROVE domain family, member 2 Details for AL592403.2 - TROVE domain family, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20822 Tuberculist Genomic Region	211586 transcription factor Dp 2 Details for - - transcription factor Dp 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 211586 Tuberculist Genomic Region
216134 pyridoxal (pyridoxine, vitamin B6) kinase Details for - - pyridoxal (pyridoxine, vitamin B6) kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216134 Tuberculist Genomic Region	234865 nucleoporin 133 Details for - - nucleoporin 133 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234865 Tuberculist Genomic Region
66841 electron transferring flavoprotein, dehydrogenase Details for - - electron transferring flavoprotein, dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66841 Tuberculist Genomic Region	66863 leucine-zipper-like transcriptional regulator, 1 Details for - - leucine-zipper-like transcriptional regulator, 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66863 Tuberculist Genomic Region
71085 Rho GTPase activating protein 19 Details for - - Rho GTPase activating protein 19 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71085 Tuberculist Genomic Region	76044 non-SMC condensin II complex, subunit G2 Details for - - non-SMC condensin II complex, subunit G2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76044 Tuberculist Genomic Region
94181 N-acetylneuraminic acid synthase (sialic acid synthase) Details for RP23-117B19.4 - N-acetylneuraminic acid synthase (sialic acid synthase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 94181 Tuberculist Genomic Region	100532 RELT-like 1 Details for - - RELT-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100532 Tuberculist Genomic Region
11545 poly (ADP-ribose) polymerase family, member 1 Details for - - poly (ADP-ribose) polymerase family, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11545 Tuberculist Genomic Region	12721 coronin, actin binding protein 1A Details for - - coronin, actin binding protein 1A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12721 Tuberculist Genomic Region
13360 7-dehydrocholesterol reductase Details for - - 7-dehydrocholesterol reductase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13360 Tuberculist Genomic Region	67959 poly-U binding splicing factor 60 Details for - - poly-U binding splicing factor 60 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67959 Tuberculist Genomic Region
72519 transmembrane protein 55A Details for RP23-379L17.2 - transmembrane protein 55A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72519 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
SP1_MA0079.2, V_SP1_03_M02281, V_KROX_Q6_M00982, V_ZFP281_01_M01597, V_SP1_Q4_01_M00932	1, 1, 1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000025	NGCCCCGCCCC	V$ETF_Q6_M00695, V$SP1SP3_Q4_M01219, ZNF740_C2H2_full_monomeric_10_1	69	CCCGCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_02_M01303, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$SP1_Q2_01_M00933, V$CKROX_Q2_M01175, V$SP4_03_M02810, V$ZFP281_01_M01597, V$SP1_Q4_01_M00932, V$ZBP89_Q4_M01816, V$SP2_01_M01783, V$MAZ_Q6_M00649, V$EGR1_06_M02744, V$KLF7_03_M02773, V$KROX_Q6_M00982, V$UF1H3BETA_Q6_M01068, V$EGR1_Q6_M01873, V$SP1_03_M02281, V$GC_01_M00255, V$ZFP281_04_M02831, V$SP1_01_M00008, V$BCL6B_04_M02844, V$E2F3_Q6_M02089, V$WT1_Q6_01_M02036, V$MAZR_01_M00491, V$GKLF_02_M01588, V$SMAD4_04_M02898, V$ZFP410_04_M02936, V$MAZ_Q6_01_M02023, V$ZNF219_01_M01122, V$KLF15_Q2_M01714, V$CACD_01_M01113, V$ZFP740_03_M02834, Sp4.1, Egr1.1, Klf7.1, Zfp281.2, Bcl6b.2, Smad3.1, Zfp410.1, Zfp740.1, Zif268.1, Klf7.2, KLF16_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, KLF13_C2H2_full_monomeric_18_1, SP1_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.61	GCGCGA	V$ZFP161_04_M02933, V$E2F_03_M00516, Zfp161.2, E2F2.1, E2F3.1, Zfp161.1	1.85	CGCTCGGA	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.63	CCGCCG	NA	NA	0.81	CTAGACCA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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