PITA_160 megaCluster: 11 Residual: 0.21 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_160	11	0.21	15	0	0.904276	0

Members

Displaying 1 - 32 of 32

109900 argininosuccinate lyase Details for - - argininosuccinate lyase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109900 Tuberculist Genomic Region	16774 laminin, alpha 3 Details for - - laminin, alpha 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16774 Tuberculist Genomic Region
19139 phosphoribosyl pyrophosphate synthetase 1 Details for RP23-137E3.3 - phosphoribosyl pyrophosphate synthetase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19139 Tuberculist Genomic Region	216987 UTP6, small subunit (SSU) processome component, homolog (yeast) Details for RP23-253E9.3 - UTP6, small subunit (SSU) processome component, homolog (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216987 Tuberculist Genomic Region
227620 UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 Details for RP23-47P18.3 - UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227620 Tuberculist Genomic Region	66818 small integral membrane protein 7 Details for - - small integral membrane protein 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66818 Tuberculist Genomic Region
68636 fumarylacetoacetate hydrolase domain containing 1 Details for MNCb-4134 - fumarylacetoacetate hydrolase domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68636 Tuberculist Genomic Region	71706 solute carrier family 46, member 3 Details for - - solute carrier family 46, member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71706 Tuberculist Genomic Region
72103 aprataxin and PNKP like factor Details for - - aprataxin and PNKP like factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72103 Tuberculist Genomic Region	100503386 predicted gene 4980 Details for - - predicted gene 4980 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503386 Tuberculist Genomic Region
110446 acetyl-Coenzyme A acetyltransferase 1 Details for - - acetyl-Coenzyme A acetyltransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110446 Tuberculist Genomic Region	13194 damage specific DNA binding protein 1 Details for - - damage specific DNA binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13194 Tuberculist Genomic Region
20719 serine (or cysteine) peptidase inhibitor, clade B, member 6a Details for RP23-262J21.1 - serine (or cysteine) peptidase inhibitor, clade B, member 6a GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20719 Tuberculist Genomic Region	211986 transmembrane protein 18 Details for - - transmembrane protein 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 211986 Tuberculist Genomic Region
212285 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 Details for - - ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 212285 Tuberculist Genomic Region	230145 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 Details for RP23-337N2.6 - UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230145 Tuberculist Genomic Region
24014 ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) Details for - - ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 24014 Tuberculist Genomic Region	245670 Ras-related GTP binding B Details for RP23-180D16.3 - Ras-related GTP binding B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245670 Tuberculist Genomic Region
28040 DNA segment, Chr 6, Wayne State University 163, expressed Details for - - DNA segment, Chr 6, Wayne State University 163, expressed GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 28040 Tuberculist Genomic Region	56786 TMEM9 domain family, member B Details for - - TMEM9 domain family, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56786 Tuberculist Genomic Region
57344 arsenic (+3 oxidation state) methyltransferase Details for - - arsenic (+3 oxidation state) methyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57344 Tuberculist Genomic Region	58248 RIKEN cDNA 1700123O20 gene Details for MNCb-2990 - RIKEN cDNA 1700123O20 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 58248 Tuberculist Genomic Region
67201 glyoxalase domain containing 4 Details for RP23-147P4.6 - glyoxalase domain containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67201 Tuberculist Genomic Region	67834 isocitrate dehydrogenase 3 (NAD+) alpha Details for - - isocitrate dehydrogenase 3 (NAD+) alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67834 Tuberculist Genomic Region
74600 mitochondrial ribosomal protein L47 Details for - - mitochondrial ribosomal protein L47 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74600 Tuberculist Genomic Region	66335 ATPase, H+ transporting, lysosomal V1 subunit C1 Details for - - ATPase, H+ transporting, lysosomal V1 subunit C1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66335 Tuberculist Genomic Region
50799 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 Details for - - solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50799 Tuberculist Genomic Region	233056 zinc finger protein 790 Details for - - zinc finger protein 790 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233056 Tuberculist Genomic Region
68839 ankyrin repeat domain 46 Details for - - ankyrin repeat domain 46 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68839 Tuberculist Genomic Region	109778 biliverdin reductase A Details for RP23-26A12.2 - biliverdin reductase A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109778 Tuberculist Genomic Region
226646 NADH dehydrogenase (ubiquinone) Fe-S protein 2 Details for - - NADH dehydrogenase (ubiquinone) Fe-S protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226646 Tuberculist Genomic Region	66455 canopy 4 homolog (zebrafish) Details for - - canopy 4 homolog (zebrafish) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66455 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
ESRRB_nuclearreceptor_DBD_monomeric_11_1	0.40625	0.000018

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.05	AAAASWAANMAA	NA	3900	CAGGGGGCGGGG	SP1_MA0079.2, V$SP1_Q2_01_M00933, V$SP1_03_M02281, V$SP1_Q6_M00196, V$ZFP281_01_M01597, V$SP1_Q6_01_M00931, V$E2F3_Q6_M02089, V$SP4_Q5_M01273, V$SP4_03_M02810, V$SP1_Q4_01_M00932, V$GC_01_M00255, V$SP1_02_M01303, V$SP1SP3_Q4_M01219, V$SP2_01_M01783, V$KLF7_03_M02773, V$CKROX_Q2_M01175, V$SP1_01_M00008, V$ETF_Q6_M00695, V$MAZ_Q6_M00649, V$MAZ_Q6_01_M02023, V$EGR1_Q6_M01873, V$MAZR_01_M00491, V$ZBP89_Q4_M01816, V$UF1H3BETA_Q6_M01068, V$ZFP281_04_M02831, V$KROX_Q6_M00982, V$RNF96_01_M01199, V$SMAD4_04_M02898, V$CACBINDINGPROTEIN_Q6_M00720, V$ZNF219_01_M01122, V$E2F_Q2_M00803, V$WT1_Q6_M01118, V$EGR1_06_M02744, V$WT1_Q6_01_M02036, V$EKLF_Q5_M01874, V$CTCF_01_M01200, V$INSM1_01_M02268, Sp4.1, Klf7.1, Zfp281.2, Smad3.1, Egr1.1, Zfp740.1, Bcl6b.2, Zfp410.1, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, ZNF740_C2H2_full_monomeric_10_1, ZIC3_C2H2_full_monomeric_15_1, KLF13_C2H2_full_monomeric_18_1, ZIC1_C2H2_full_monomeric_14_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.17	ATCGCG	NA	1.27	GGCTTCCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.73	CCTGTTAA	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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