PITA_185 megaCluster: 2 Residual: 0.20 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_185	2	0.20	15	0.002	0.915089	0

Members

Displaying 1 - 22 of 22

11541 adenosine A2b receptor Details for RP23-330N10.1 - adenosine A2b receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11541 Tuberculist Genomic Region	11758 peroxiredoxin 6 Details for - - peroxiredoxin 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11758 Tuberculist Genomic Region
14733 glypican 1 Details for - - glypican 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14733 Tuberculist Genomic Region	14745 lysophosphatidic acid receptor 1 Details for RP23-170A3.2 - lysophosphatidic acid receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14745 Tuberculist Genomic Region
217344 rhomboid 5 homolog 2 (Drosophila) Details for RP23-313J14.3 - rhomboid 5 homolog 2 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217344 Tuberculist Genomic Region	230779 serine incorporator 2 Details for RP23-12J1.7 - serine incorporator 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230779 Tuberculist Genomic Region
30805 solute carrier family 22 (organic cation transporter), member 4 Details for RP23-354D12.1 - solute carrier family 22 (organic cation transporter), member 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30805 Tuberculist Genomic Region	74481 basic leucine zipper transcription factor, ATF-like 2 Details for - - basic leucine zipper transcription factor, ATF-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74481 Tuberculist Genomic Region
11540 adenosine A2a receptor Details for - - adenosine A2a receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11540 Tuberculist Genomic Region	11988 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 Details for - - solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11988 Tuberculist Genomic Region
17295 met proto-oncogene Details for - - met proto-oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17295 Tuberculist Genomic Region	232889 phospholipase A2, group IVC (cytosolic, calcium-independent) Details for - - phospholipase A2, group IVC (cytosolic, calcium-independent) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 232889 Tuberculist Genomic Region
23797 thymoma viral proto-oncogene 3 Details for - - thymoma viral proto-oncogene 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23797 Tuberculist Genomic Region	245126 T cell-interacting, activating receptor on myeloid cells 1 Details for - - T cell-interacting, activating receptor on myeloid cells 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245126 Tuberculist Genomic Region
246779 interleukin 27 Details for - - interleukin 27 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 246779 Tuberculist Genomic Region	269356 solute carrier family 4, sodium bicarbonate transporter-like, member 11 Details for - - solute carrier family 4, sodium bicarbonate transporter-like, member 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269356 Tuberculist Genomic Region
381560 X Kell blood group precursor related family member 8 homolog Details for RP23-442A20.2 - X Kell blood group precursor related family member 8 homolog GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381560 Tuberculist Genomic Region	56068 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 Details for RP23-340M18.4 - Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56068 Tuberculist Genomic Region
629303 predicted gene 11435 Details for RP23-320E6.1 - predicted gene 11435 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 629303 Tuberculist Genomic Region	70086 cysteinyl leukotriene receptor 2 Details for - - cysteinyl leukotriene receptor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70086 Tuberculist Genomic Region
72075 opioid growth factor receptor Details for RP23-74K21.5 - opioid growth factor receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72075 Tuberculist Genomic Region	98432 PH domain and leucine rich repeat protein phosphatase 1 Details for - - PH domain and leucine rich repeat protein phosphatase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 98432 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_HLF_01_M00260	0.227273	0.000000548

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.3	CCCCACCCCNR	Klf4_MA0039.2, SP1_MA0079.2, V$SP1_Q2_01_M00933, V$KLF7_03_M02773, V$SP4_Q5_M01273, V$GKLF_02_M01588, V$SP1_02_M01303, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$CACCCBINDINGFACTOR_Q6_M00721, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$CKROX_Q2_M01175, V$CACD_01_M01113, V$GC_01_M00255, V$EKLF_Q5_M01874, V$MAZ_Q6_M00649, V$SP1_03_M02281, V$MAZR_01_M00491, V$ZFP281_04_M02831, V$MAZ_Q6_01_M02023, V$BCL6B_04_M02844, V$KLF15_Q2_M01714, V$FKLF_Q5_M01837, V$ZBP89_Q4_M01816, V$KROX_Q6_M00982, V$ZNF219_01_M01122, V$ZFP740_03_M02834, V$CACBINDINGPROTEIN_Q6_M00720, V$ZFP410_04_M02936, V$SP1_01_M00008, V$EGR1_Q6_M01873, V$EGR2_Q6_M02092, V$SOX14_04_M02901, V$SP1SP3_Q4_M01219, V$AML2_Q3_01_M01854, V$EGR1_06_M02744, V$PAX4_03_M00378, V$GLI3_Q5_01_M01657, V$AML2_Q3_M01814, Klf7.1, Zfp281.2, Bcl6b.2, Zfp740.1, Zfp410.1, Sox13.2, Egr1.1, Smad3.1, Ascl2.2, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1	3.2	CTCMGCCYCCAG	SP1_MA0079.2, V$SP1_03_M02281, V$ZFP281_01_M01597, V$NFE4_Q5_M02105, V$ETF_Q6_M00695, V$SP1_Q2_01_M00933, V$SP1_Q6_M00196, V$GC_01_M00255

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
0.97	TCGCGC	V$E2F_03_M00516, V$ZFP161_04_M02933, V$E2F_Q6_01_M00920, V$E2F2_03_M02742, V$E2F1_Q3_01_M00938, V$E2F4DP1_01_M00738, V$E2F_02_M00050, V$E2F_01_M00024, V$E2F1DP1RB_01_M00740, V$ZF5_01_M00716, Zfp161.2, E2F2.1, E2F3.1, Zfp161.1	1.3	CTTCGCGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.71	CCGTGG	NA	NA	0.77	NNCYGTGG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-223	0.5	0.0000455

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